The role of altered nucleotide excision repair and UVB-induced DNA damage in melanomagenesis

International Journal of Molecular Sciences

Volumn 14, Issue 1, 2013, Pages 1132-1151

  Budden, Timothy ^a   Bowden, Nikola A ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

6 4 photoproducts; Apoptosis; Cell death; Cyclobutane pyrimidine dimers; DNA damage; DNA repair; Melanoma; Nucleotide excision repair; Ultraviolet light; UVB

Indexed keywords

B RAF KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLINE; CYTOSINE; DNA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; NUCLEIC ACID BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN P53; PYRIMIDINE DIMER; RAS PROTEIN; THYMINE; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP A PROTEIN; XERODERMA PIGMENTOSUM GROUP C PROTEIN; XERODERMA PIGMENTOSUM GROUP D PROTEIN; XERODERMA PIGMENTOSUM GROUP E PROTEIN;

AMINO ACID SUBSTITUTION; CANCER INCIDENCE; CANCER RISK; CARCINOGENESIS; CELL DEATH; CELL GROWTH; DNA DAMAGE; DNA STRUCTURE; EXCISION REPAIR; GENE MUTATION; GENETIC COMPLEMENTATION; HETEROZYGOSITY LOSS; HOMEOSTASIS; HUMAN; MELANOMA; MUTAGENICITY; NONHUMAN; ONCOGENE; RADIATION EXPOSURE; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN CANCER; TUMOR SUPPRESSOR GENE; ULTRAVIOLET B RADIATION; XERODERMA PIGMENTOSUM; DNA REPAIR; GENETICS; MUTATION; RADIATION INDUCED NEOPLASM; RADIATION RESPONSE; SIGNAL TRANSDUCTION; SKIN TUMOR; ULTRAVIOLET RADIATION;

DNA DAMAGE; DNA REPAIR; HUMANS; MELANOMA; MUTATION; NEOPLASMS, RADIATION-INDUCED; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

EID: 84878649723     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14011132     Document Type: Review

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