Homologous recombination is involved in transcription-coupled repair of UV damage in Saccharomyces cerevisiae

EMBO Journal

Volumn 24, Issue 11, 2005, Pages 1999-2010

  Aboussekhra, Abdelilah ^a   Al Sharif, Ibtehaj S ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

RAD26; RAD51; S. cerevisiae; Transcription coupled repair; UV damage

Indexed keywords

ADENOSINE TRIPHOSPHATASE; PROTEIN RAD1; PROTEIN RAD14; RAD51 PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DIPLOIDY; DNA STRAND; DNA TRANSCRIPTION; EXCISION REPAIR; FUNGAL GENE; GENE DELETION; HAPLOIDY; HOMOLOGOUS RECOMBINATION; MICROBIAL ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAD26 GENE; RADIATION INJURY REPAIR; SACCHAROMYCES CEREVISIAE; ULTRAVIOLET RADIATION; YEAST CELL;

ADENOSINE TRIPHOSPHATASES; CELL CYCLE; DIPLOIDY; DNA DAMAGE; DNA REPAIR; DNA, FUNGAL; DNA-BINDING PROTEINS; ENDONUCLEASES; HAPLOIDY; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 21244483140     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600665     Document Type: Article

References (50)

1. Abbott DW, Thompson ME, Robinson-Benion C, Tomlinson G, Jensen RA, Holt JT (1999) BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair. J Biol Chem 274: 18808-18812
2. Aboussekhra A, Chanet R, Adjiri A, Fabre F (1992) Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins. Mol Cell Biol 12: 3224-3234
3. Aboussekhra A, Thoma F (1998) Nucleotide excision repair and photolyase preferentially repair the nontranscribed strand of RNA polymerase III-transcribed genes in Saccharomyces cerevisiae. Genes Dev 12: 411-421
4. Aboussekhra A, Vialard JE, Morrison DE, de la Torre-Ruiz MA, Cernakova L, Fabre F, Lowndes NF (1996) A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription. EMBO J 15: 3912-3922
5. Aguilera A (2002) The connection between transcription and genomic instability. EMBO J 21: 195-201
6. Awrey DE, Weilbaecher RG, Hemming SA, Orlicky SM, Kane CM, Edwards AM (1997) Transcription elongation through DNA arrest sites. A multistep process involving both RNA polymerase II subunit RPB9 and TFIIS. J Biol Chem 272: 14747-14754
7. Basile G, Aker M, Mortimer RK (1992) Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51. Mol Cell Biol 12: 3235-3246
8. Baumann P, Benson FE, West SC (1996) Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell 87: 757-766
9. Benson FE, Stasiak A, West SC (1994) Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA. EMBO J 13: 5764-5771
10. Bhatia PK, Verhage RA, Brouwer J, Friedberg EC (1996) Molecular cloning and characterization of Saccharomyces cerevisiae RAD28, the yeast homolog of the human Cockayne syndrome A (CSA) gene. J Bacteriol 178: 5977-5988
11. Chavez S, Beilharz T, Rondon AG, Erdjument-Bromage H, Tempst P, Svejstrup JQ, Lithgow T, Aguilera A (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19: 5824-5834
12. de Boer J, Hoeijmakers JH (2000) Nucleotide excision repair and human syndromes. Carcinogenesis 21: 453-460
13. de Laat WL, Jaspers NG, Hoeijmakers JH (1999) Molecular mechanism of nucleotide excision repair. Genes Dev 13: 768-785
14. Eisen JA, Sweder KS, Hanawalt PC (1995) Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nudac Acids Res 23: 2715-2723
15. Game JC (2000) The Saccharomyces repair genes at the end of the century. Mutat Res 451: 277-293
16. Gonzalez-Barrera S, Garcia-Rubio M, Aguilera A (2002) Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae. Genetics 162: 603-614
17. Guzder SN, Habraken Y, Sung P, Prakash L, Prakash S (1996) RAD26, the yeast homolog of human Cockayne's syndrome group B gene, encodes a DNA-dependent ATPase. J Biol Chem 271: 18314-18317
18. Guzder SN, Sung P, Prakash L, Prakash S (1993) Yeast DNA-repair gene RAD14 encodes a zinc metalloprotein with affinity for ultraviolet-damaged DNA. Proc Natl Acad Sci USA 90: 5433-5437
19. Hanawalt PC (2002) Subpathways of nucleotide excision repair and their regulation. Oncogene 21: 8949-8956
20. Hanawalt PC, Ford JM, Lloyd DR (2003) Functional characterization of global genomic DNA repair and its implications for cancer. Mutat Res 544: 107-114
21. Hemming SA, Edwards AM (2000) Yeast RNA polymerase II subunit RPB9. Mapping of domains required for transcription elongation. J Biol Chem 275: 2288-2294
22. Hemming SA, Jansma DB, Macgregor PF, Goryachev A, Friesen JD, Edwards AM (2000) RNA polymerase II subunit Rpb9 regulates transcription elongation in vivo. J Biol Chem 275: 35506-35511
23. Henning KA, Li L, Iyer N, McDaniel LD, Reagan MS, Legerski R, Schultz RA, Stefanini M, Lehmann AR, Mayne LV, Friedberg EC (1995) The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell 82: 555-564
24. Kadyk LC, Hartwell LH (1993) Replication-dependent sister chromatid recombination in rad1 mutants of Saccharomyces cerevisiae. Genetics 133: 469-487
25. Kaine BP, Mehr IJ, Woese CR (1994) The sequence, and its evolutionary implications, of a Thermococcus celer protein associated with transcription. Proc Natl Acad Sci USA 91: 3854-3856
26. Le Page F, Randrianarison V, Marot D, Cabannes J, Perricaudet M, Feunteun J, Sarasin A (2000) BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells. Cancer Res 60: 5548-5552
27. Lee SK, Yu SL, Prakash L, Prakash S (2001) Requirement for yeast RAD26, a homolog of the human CSB gene, in elongation by RNA polymerase II. Mol Cell Biol 21: 8651-8656
28. Lee SK, Yu SL, Prakash L, Prakash S (2002) Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription, implications for Cockayne syndrome. Cell 109: 823-834
29. Li S, Smerdon MJ (2002) Rpb4 and Rpb9 mediate subpathways of transcription-coupled DNA repair in Saccharomyces cerevisiae. EMBO J 21: 5921-5929
30. Lommel L, Carswell-Crumpton C, Hanawalt PC (1995) Preferential repair of the transcribed DNA strand in the dihydrofolate reductase gene throughout the cell cycle in UV-irradiated human cells. Mutat Res 336: 181-192
31. Petersen LN, Orren DK, Bohr VA (1995) Gene-specific and strand-specific DNA repair in the G1 and G2 phases of the cell cycle. Mol Cell Biol 15: 3731-3737
32. Rodriguez K, Talamantez J, Huang W, Reed SH, Wang Z, Chen L, Feaver WJ, Friedberg EC, Tomkinson AE (1998) Affinity purification and partial characterization of a yeast multiprotein complex for nucleotide excision repair using histidine-tagged Rad14 protein. J Biol Chem 273: 34180-34189
33. Selby CP, Sancar A (1993) Molecular mechanism of transcription-repair coupling. Science 260: 53-58
34. Selby CP, Sancar A (1997) Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase H. J Biol Chem 272: 1885-1890
35. Shinohara A, Ogawa H, Ogawa T (1992) Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein. Cell 69: 457-470
36. Stauffer ME, Chazin WJ (2004) Physical interaction between replication protein A and Rad51 promotes exchange on single-stranded DNA. J Biol Chem 279: 25638-25645
37. Sugiyama T, Zaitseva EM, Kowalczykowski SC (1997) A single-stranded DNA-binding protein is needed for efficient presynaptic complex formation by the Saccharomyces cerevisiae Rad51 protein. J Biol Chem 272: 7940-7945
38. Svejstrup JQ (2002) Mechanisms of transcription-coupled DNA repair. Nat Rev Mol Cell Biol 3: 21-29
39. Svejstrup JQ (2003) Rescue of arrested RNA polymerase II complexes. J Cell Sci 116: 447-451
40. Teng Y, Waters R (2000) Excision repair at the level of the nucleotide in the upstream control region, the coding sequence and in the region where transcription terminates of the Saccharomyces cerevisiae MFA2 gene and the role of RAD26. Nucleic Acids Res 28: 1114-1119
41. Thoma F (1999) Light and dark in chromatin repair: repair of UV-induced DNA lesions by photolyase and nucleotide excision repair. EMBO J 18: 6585-6598
42. Tomkinson AE, Bardwell AJ, Bardwell L, Tappe NJ, Friedberg EC (1993) Yeast DNA repair and recombination proteins Rad1 and Radio constitute a single-stranded-DNA endonuclease. Nature 362: 860-862
43. Tornaletti S, Reines D, Hanawalt PC (1999) Structural characterization of RNA polymerase II complexes arrested by a cyclobutane pyrimidine dimer in the transcribed strand of template DNA. J Biol Chem 274: 24124-24130
44. Troelstra C, van Gool A, de Wit J, Vermeulen W, Bootsma D, Hoeijmakers JH (1992) ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell 71: 939-953
45. van Gool AJ, Verhage R, Swagemakers SM, van de Putte P, Brouwer J, Troelstra C, Bootsma D, Hoeijmakers JH (1994) RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6. EMBO J 13: 5361-5369
46. van Hoffen A, Natarajan AT, Mayne LV, van Zeeland AA, Mullenders LH, Venema J (1993) Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells. Nucleic Acids Res 21: 5890-5895
47. Venema J, Mullenders LH, Natarajan AT, van Zeeland AA, Mayne LV (1990) The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc Natl Acad Sci USA 87: 4707-4711
48. Venkitaraman AR (2002) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108: 171-182
49. Verhage RA, van Gool AJ, de Groot N, Hoeijmakers JH, van de Putte P, Brouwer J (1996) Double mutants of Saccharomyces cerevisiae with alterations in global genome and transcription-coupled repair. Mol Cell Biol 16: 496-502
50. Wellinger RE, Thoma F (1997) Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene. EMBO J 16: 5046-5056