JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses food intake and gastric emptying with the elevation of plasma peptide YY and glucagon-like peptide-1 in a dietary fat-dependent manner

Journal of Pharmacology and Experimental Therapeutics

Volumn 336, Issue 3, 2011, Pages 850-856

  Hata, Takahiro ^a   Mera, Yasuko ^a   Ishii, Yukihito ^a   Tadaki, Hironobu ^a   Tomimoto, Daisuke ^a   Kuroki, Yukiharu ^a   Kawai, Takashi ^a   Ohta, Takeshi ^a   Kakutani, Makoto ^a  

^a JAPAN TOBACCO INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ; CHOLESTEROL; DIETHYL 2 [[3 DIMETHYLCARBAMOYL 4 [(4' TRIFLUOROMETHYLBIPHENYL 2 CARBONYL) AMINO] PHENYL]ACETYLOXYMETHYL] 2 PHENYLMALONATE; FATTY ACID; GLUCAGON LIKE PEPTIDE 1; JTT 130; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITOR; PEPTIDE YY; TETRAHYDROLIPSTATIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FAT INTAKE; FOOD INTAKE; LIPID DIET; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SATIETY; STOMACH EMPTYING;

ANIMALS; APPETITE DEPRESSANTS; BENZAMIDES; BIOLOGICAL MARKERS; CARRIER PROTEINS; DIETARY FATS; EATING; GASTRIC EMPTYING; GLUCAGON-LIKE PEPTIDE 1; MALE; MALONATES; PEPTIDE YY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79951961905     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.176560     Document Type: Article

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