메뉴 건너뛰기




Volumn 2013, Issue , 2013, Pages

Role of regulatory T cells in pathogenesis and biological therapy of multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; BASILIXIMAB; BETA INTERFERON; CD20 ANTIBODY; CD52 ANTIGEN; DACLIZUMAB; FINGOLIMOD; GAMMA INTERFERON; GLATIRAMER; IMMUNOMODULATING AGENT; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MONOCLONAL ANTIBODY; NATALIZUMAB; OCRELIZUMAB; OFATIMUMAB; RITUXIMAB; UNCLASSIFIED DRUG;

EID: 84878633653     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/963748     Document Type: Review
Times cited : (90)

References (105)
  • 1
    • 33646162855 scopus 로고    scopus 로고
    • A unified theory of central tolerance in the thymus
    • 2-s2.0-33646162855 10.1016/j.it.2006.03.004
    • Liu Y. J., A unified theory of central tolerance in the thymus. Trends in Immunology 2006 27 5 215 221 2-s2.0-33646162855 10.1016/j.it.2006.03.004
    • (2006) Trends in Immunology , vol.27 , Issue.5 , pp. 215-221
    • Liu, Y.J.1
  • 2
    • 23144450643 scopus 로고    scopus 로고
    • Regulatory T cells: Development, function and role in autoimmunity
    • DOI 10.1016/j.autrev.2005.01.007, PII S1568997205000194
    • Lan R. Y., Ansari A. A., Lian Z. X., Gershwin M. E., Regulatory T cells: development, function and role in autoimmunity. Autoimmunity Reviews 2005 4 6 351 363 2-s2.0-23144450643 10.1016/j.autrev.2005.01.007 (Pubitemid 41080072)
    • (2005) Autoimmunity Reviews , vol.4 , Issue.6 , pp. 351-363
    • Lan, R.Y.1    Ansari, A.A.2    Lian, Z.-X.3    Gershwin, M.E.4
  • 3
    • 77954141914 scopus 로고    scopus 로고
    • FOXP3 + regulatory T cells in the human immune system
    • 2-s2.0-77954141914 10.1038/nri2785
    • Sakaguchi S., Miyara M., Costantino C. M., Hafler D. A., FOXP3 + regulatory T cells in the human immune system. Nature Reviews Immunology 2010 10 7 490 500 2-s2.0-77954141914 10.1038/nri2785
    • (2010) Nature Reviews Immunology , vol.10 , Issue.7 , pp. 490-500
    • Sakaguchi, S.1    Miyara, M.2    Costantino, C.M.3    Hafler, D.A.4
  • 5
    • 78650209225 scopus 로고    scopus 로고
    • T Regulatory cells maintain intestinal homeostasis by suppressing γ δ T cells
    • 2-s2.0-78650209225 10.1016/j.immuni.2010.10.014
    • Park S. G., Mathur R., Long M., Hosh N., Hao L., Hayden M. S., Ghosh S., T Regulatory cells maintain intestinal homeostasis by suppressing γ δ T cells. Immunity 2010 33 5 791 803 2-s2.0-78650209225 10.1016/j.immuni.2010.10.014
    • (2010) Immunity , vol.33 , Issue.5 , pp. 791-803
    • Park, S.G.1    Mathur, R.2    Long, M.3    Hosh, N.4    Hao, L.5    Hayden, M.S.6    Ghosh, S.7
  • 6
    • 79952938313 scopus 로고    scopus 로고
    • Maturation of effector regulatory T cells
    • 2-s2.0-79952938313 10.1038/ni0411-283
    • Ohkura N., Sakaguchi S., Maturation of effector regulatory T cells. Nature Immunology 2011 12 4 283 284 2-s2.0-79952938313 10.1038/ni0411-283
    • (2011) Nature Immunology , vol.12 , Issue.4 , pp. 283-284
    • Ohkura, N.1    Sakaguchi, S.2
  • 7
    • 78650731638 scopus 로고    scopus 로고
    • Foxo: In command of T lymphocyte homeostasis and tolerance
    • 2-s2.0-78650731638 10.1016/j.it.2010.10.005
    • Ouyang W., Li M. O., Foxo: in command of T lymphocyte homeostasis and tolerance. Trends in Immunology 2011 32 1 26 33 2-s2.0-78650731638 10.1016/j.it.2010.10.005
    • (2011) Trends in Immunology , vol.32 , Issue.1 , pp. 26-33
    • Ouyang, W.1    Li, M.O.2
  • 8
    • 27544446622 scopus 로고    scopus 로고
    • + regulatory T cells in the absence of interleukin 2 signaling
    • DOI 10.1038/ni1264, PII N1264
    • + regulatory T cells in the absence of interleukin 2 signaling. Nature Immunology 2005 6 11 1152 1159 2-s2.0-27544446622 10.1038/ni1264 (Pubitemid 41541793)
    • (2005) Nature Immunology , vol.6 , Issue.11 , pp. 1152-1159
    • D'Cruz, L.M.1    Klein, L.2
  • 9
    • 15544384475 scopus 로고    scopus 로고
    • + T regulatory cell development during the neonatal period
    • DOI 10.1084/jem.20041179
    • + T regulatory cell development during the neonatal period. Journal of Experimental Medicine 2005 201 5 769 777 2-s2.0-15544384475 10.1084/jem.20041179 (Pubitemid 40403028)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.5 , pp. 769-777
    • Bayer, A.L.1    Yu, A.2    Adeegbe, D.3    Malek, T.R.4
  • 10
    • 15444374646 scopus 로고    scopus 로고
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • DOI 10.1084/jem.20041982
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. Journal of Experimental Medicine 2005 201 5 723 735 2-s2.0-15444374646 10.1084/jem.20041982 (Pubitemid 40395118)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.5 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 11
    • 78649447854 scopus 로고    scopus 로고
    • Regulatory T cells: The suppressor arm of the immune system
    • 2-s2.0-78649447854 10.1016/j.autrev.2010.08.013
    • Langier S., Sade K., Kivity S., Regulatory T cells: the suppressor arm of the immune system. Autoimmunity Reviews 2010 10 2 112 115 2-s2.0-78649447854 10.1016/j.autrev.2010.08.013
    • (2010) Autoimmunity Reviews , vol.10 , Issue.2 , pp. 112-115
    • Langier, S.1    Sade, K.2    Kivity, S.3
  • 12
    • 65549136983 scopus 로고    scopus 로고
    • + T regulatory cell-mediated suppression
    • 2-s2.0-65549136983 10.1016/j.immuni.2009.04.010
    • + T regulatory cell-mediated suppression. Immunity 2009 30 5 636 645 2-s2.0-65549136983 10.1016/j.immuni. 2009.04.010
    • (2009) Immunity , vol.30 , Issue.5 , pp. 636-645
    • Shevach, E.M.1
  • 13
    • 78649897032 scopus 로고    scopus 로고
    • Human regulatory T cells in autoimmune diseases
    • 2-s2.0-78649897032 10.1016/j.coi.2010.08.012
    • Cvetanovich G. L., Hafler D. A., Human regulatory T cells in autoimmune diseases. Current Opinion in Immunology 2010 22 6 753 760 2-s2.0-78649897032 10.1016/j.coi.2010.08.012
    • (2010) Current Opinion in Immunology , vol.22 , Issue.6 , pp. 753-760
    • Cvetanovich, G.L.1    Hafler, D.A.2
  • 15
    • 78049318852 scopus 로고    scopus 로고
    • + regulatory T cells
    • 2-s2.0-78049318852 10.1016/j.coi.2010.08.004
    • + regulatory T cells. Current Opinion in Immunology 2010 22 5 575 582 2-s2.0-78049318852 10.1016/j.coi.2010.08.004
    • (2010) Current Opinion in Immunology , vol.22 , Issue.5 , pp. 575-582
    • Hori, S.1
  • 16
    • 84862777225 scopus 로고    scopus 로고
    • Extrathymically generated regulatory T cells control mucosal TH2 inflammation
    • Josefowicz S. Z., Niec R. E., Kim H. Y., Treuting P., Chinen T., Zheng Y., Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature 2012 482 7385 395 399
    • (2012) Nature , vol.482 , Issue.7385 , pp. 395-399
    • Josefowicz, S.Z.1    Niec, R.E.2    Kim, H.Y.3    Treuting, P.4    Chinen, T.5    Zheng, Y.6
  • 18
    • 80054880898 scopus 로고    scopus 로고
    • Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naive/memory Breg ratio during a relapse but not in remission
    • Knippenberg S., Peelen E., Smolders J., Thewissen M., Menheere P., Cohen Tervaert J. W., Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naive/memory Breg ratio during a relapse but not in remission. Journal of Neuroimmunology 2011 239 1-2 80 86
    • (2011) Journal of Neuroimmunology , vol.239 , Issue.1-2 , pp. 80-86
    • Knippenberg, S.1    Peelen, E.2    Smolders, J.3    Thewissen, M.4    Menheere, P.5    Cohen Tervaert, J.W.6
  • 20
    • 77950070632 scopus 로고    scopus 로고
    • + T cell immunity
    • 2-s2.0-77950070632 10.1038/nri2729
    • + T cell immunity. Nature Reviews Immunology 2010 10 4 236 247 2-s2.0-77950070632 10.1038/nri2729
    • (2010) Nature Reviews Immunology , vol.10 , Issue.4 , pp. 236-247
    • Lund, F.E.1    Randall, T.D.2
  • 21
    • 78649499723 scopus 로고    scopus 로고
    • Regulatory B cells: Evidence, developmental origin and population diversity
    • 2-s2.0-78649499723 10.1016/j.molimm.2010.09.010
    • Vitale G., Mion F., Pucillo C., Regulatory B cells: evidence, developmental origin and population diversity. Molecular Immunology 2010 48 1-3 1 8 2-s2.0-78649499723 10.1016/j.molimm.2010.09.010
    • (2010) Molecular Immunology , vol.48 , Issue.1-3 , pp. 1-8
    • Vitale, G.1    Mion, F.2    Pucillo, C.3
  • 22
    • 84868619716 scopus 로고    scopus 로고
    • Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions
    • Yoshizaki A., Miyagaki T., DiLillo D. J., Matsushita T., Horikawa M., Kountikov E. I., Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. Nature 2012 491 7423 264 268
    • (2012) Nature , vol.491 , Issue.7423 , pp. 264-268
    • Yoshizaki, A.1    Miyagaki, T.2    Dilillo, D.J.3    Matsushita, T.4    Horikawa, M.5    Kountikov, E.I.6
  • 23
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis
    • DOI 10.1146/annurev.immunol.23.021704.115707
    • Sospedra M., Martin R., Immunology of multiple sclerosis. Annual Review of Immunology 2005 23 683 747 2-s2.0-17644396349 10.1146/annurev.immunol.23. 021704.115707 (Pubitemid 40563183)
    • (2005) Annual Review of Immunology , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 24
    • 84860735624 scopus 로고    scopus 로고
    • Vitamin D and multiple sclerosis: Epidemiology, immunology, and genetics
    • Simon K. C., Munger K. L., Ascherio A., Vitamin D and multiple sclerosis: epidemiology, immunology, and genetics. Current Opinion in Neurology 2012 25 3 246 251
    • (2012) Current Opinion in Neurology , vol.25 , Issue.3 , pp. 246-251
    • Simon, K.C.1    Munger, K.L.2    Ascherio, A.3
  • 25
    • 77955251897 scopus 로고    scopus 로고
    • Vitamin D: Modulator of the immune system
    • 2-s2.0-77955251897 10.1016/j.coph.2010.04.001
    • Baeke F., Takiishi T., Korf H., Gysemans C., Mathieu C., Vitamin D: modulator of the immune system. Current Opinion in Pharmacology 2010 10 4 482 496 2-s2.0-77955251897 10.1016/j.coph.2010.04.001
    • (2010) Current Opinion in Pharmacology , vol.10 , Issue.4 , pp. 482-496
    • Baeke, F.1    Takiishi, T.2    Korf, H.3    Gysemans, C.4    Mathieu, C.5
  • 26
    • 84863988286 scopus 로고    scopus 로고
    • Type17 T-cells in central nervous system autoimmunity and tumors
    • Okada H., Khoury S. J., Type17 T-cells in central nervous system autoimmunity and tumors. Journal of Clinical Immunology 2012 32 4 802 808
    • (2012) Journal of Clinical Immunology , vol.32 , Issue.4 , pp. 802-808
    • Okada, H.1    Khoury, S.J.2
  • 27
    • 84869885852 scopus 로고    scopus 로고
    • Capture, crawl, cross: The T cell code to breach the blood-brain barriers
    • Engelhardt B., Ransohoff R. M., Capture, crawl, cross: the T cell code to breach the blood-brain barriers. Trends in Immunology 2012 33 12 579 589
    • (2012) Trends in Immunology , vol.33 , Issue.12 , pp. 579-589
    • Engelhardt, B.1    Ransohoff, R.M.2
  • 30
    • 0035896737 scopus 로고    scopus 로고
    • The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system
    • DOI 10.1084/jem.193.8.967
    • Becher B., Durell B. G., Miga A. V., Hickey W. F., Noelle R. J., The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system. Journal of Experimental Medicine 2001 193 8 967 974 2-s2.0-0035896737 10.1084/jem.193.8.967 (Pubitemid 32525869)
    • (2001) Journal of Experimental Medicine , vol.193 , Issue.8 , pp. 967-974
    • Becher, B.1    Durell, B.G.2    Miga, A.V.3    Hickey, W.F.4    Noelle, R.J.5
  • 32
    • 56149125346 scopus 로고    scopus 로고
    • Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
    • 2-s2.0-56149125346
    • O'Connor R. A., Prendergast C. T., Sabatos C. A., Lau C. W. Z., Leech M. D., Wraith D. C., Anderton S. M., Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis. Journal of Immunology 2008 181 6 3750 3754 2-s2.0-56149125346
    • (2008) Journal of Immunology , vol.181 , Issue.6 , pp. 3750-3754
    • O'Connor, R.A.1    Prendergast, C.T.2    Sabatos, C.A.3    Lau, C.W.Z.4    Leech, M.D.5    Wraith, D.C.6    Anderton, S.M.7
  • 33
    • 77956536780 scopus 로고    scopus 로고
    • T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
    • 2-s2.0-77956536780 10.1111/j.1365-2249.2010.04143.x
    • Fletcher J. M., Lalor S. J., Sweeney C. M., Tubridy N., Mills K. H. G., T cells in multiple sclerosis and experimental autoimmune encephalomyelitis. Clinical and Experimental Immunology 2010 162 1 1 11 2-s2.0-77956536780 10.1111/j.1365-2249.2010.04143.x
    • (2010) Clinical and Experimental Immunology , vol.162 , Issue.1 , pp. 1-11
    • Fletcher, J.M.1    Lalor, S.J.2    Sweeney, C.M.3    Tubridy, N.4    Mills, K.H.G.5
  • 35
    • 84867774238 scopus 로고    scopus 로고
    • What do effective treatments for multiple sclerosis tell us about the molecular mechanisms involved in pathogenesis?
    • Buzzard K. A., Broadley S. A., Butzkueven H., What do effective treatments for multiple sclerosis tell us about the molecular mechanisms involved in pathogenesis? International Journal of Molecular Sciences 2012 13 10 12665 12709
    • (2012) International Journal of Molecular Sciences , vol.13 , Issue.10 , pp. 12665-12709
    • Buzzard, K.A.1    Broadley, S.A.2    Butzkueven, H.3
  • 36
    • 70149122373 scopus 로고    scopus 로고
    • + T cells in multiple sclerosis
    • 2-s2.0-70149122373 10.1002/ana.21744
    • + T cells in multiple sclerosis. Annals of Neurology 2009 66 2 132 141 2-s2.0-70149122373 10.1002/ana.21744
    • (2009) Annals of Neurology , vol.66 , Issue.2 , pp. 132-141
    • Friese, M.A.1    Fugger, L.2
  • 38
    • 84862764046 scopus 로고    scopus 로고
    • Immunoregulatory T cells in multiple sclerosis and the effect of interferon beta and glatiramer acetate treatment on T cell subpopulations
    • Praksova P., Stourac P., Bednarik J., Vlckova E., Mikulkova Z., Michalek J., Immunoregulatory T cells in multiple sclerosis and the effect of interferon beta and glatiramer acetate treatment on T cell subpopulations. Journal of the Neurological Sciences 2012 319 1-2 18 23
    • (2012) Journal of the Neurological Sciences , vol.319 , Issue.1-2 , pp. 18-23
    • Praksova, P.1    Stourac, P.2    Bednarik, J.3    Vlckova, E.4    Mikulkova, Z.5    Michalek, J.6
  • 39
    • 33846817153 scopus 로고    scopus 로고
    • + regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients
    • DOI 10.1111/j.1365-2249.2006.03271.x
    • + regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients. Clinical and Experimental Immunology 2007 147 3 412 418 2-s2.0-33846817153 10.1111/j.1365-2249.2006.03271.x (Pubitemid 46208041)
    • (2007) Clinical and Experimental Immunology , vol.147 , Issue.3 , pp. 412-418
    • Feger, U.1    Luther, C.2    Poeschel, S.3    Melms, A.4    Tolosa, E.5    Wiendl, H.6
  • 42
    • 84862733981 scopus 로고    scopus 로고
    • Regulatory T cells in the central nervous system
    • Lowther D. E., Hafler D. A., Regulatory T cells in the central nervous system. Immunological Reviews 2012 248 1 156 169
    • (2012) Immunological Reviews , vol.248 , Issue.1 , pp. 156-169
    • Lowther, D.E.1    Hafler, D.A.2
  • 43
    • 78649526238 scopus 로고    scopus 로고
    • + regulatory T cells in human autoimmune diseases
    • 2-s2.0-78649526238 10.1038/nri2889
    • + regulatory T cells in human autoimmune diseases. Nature Reviews Immunology 2010 10 12 849 859 2-s2.0-78649526238 10.1038/nri2889
    • (2010) Nature Reviews Immunology , vol.10 , Issue.12 , pp. 849-859
    • Buckner, J.H.1
  • 45
    • 78649600894 scopus 로고    scopus 로고
    • Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis
    • 2-s2.0-78649600894 10.1002/eji.201040558
    • Schneider-Hohendorf T., Stenner M. P., Weidenfeller C., Zozulya A. L., Simon O. J., Schwab N., Wiendl H., Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis. European Journal of Immunology 2010 40 12 3581 3590 2-s2.0-78649600894 10.1002/eji.201040558
    • (2010) European Journal of Immunology , vol.40 , Issue.12 , pp. 3581-3590
    • Schneider-Hohendorf, T.1    Stenner, M.P.2    Weidenfeller, C.3    Zozulya, A.L.4    Simon, O.J.5    Schwab, N.6    Wiendl, H.7
  • 46
    • 0036838536 scopus 로고    scopus 로고
    • + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. Journal of Immunology 2002 169 9 4712 4716 2-s2.0-0036838536 (Pubitemid 35217131)
    • (2002) Journal of Immunology , vol.169 , Issue.9 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 48
    • 0017645154 scopus 로고
    • Immunoglobulin containing cells in multiple sclerosis plaques
    • Esiri M. M., Immunoglobulin containing cells in multiple sclerosis plaques. Lancet 1977 2 8036 478 480 2-s2.0-0017645154 (Pubitemid 8166586)
    • (1977) Lancet , vol.2 , Issue.8036 , pp. 478-480
    • Esiri, M.M.1
  • 49
    • 0032950794 scopus 로고    scopus 로고
    • Identification of autoantibodies associated with myelin damage in multiple sclerosis
    • DOI 10.1038/5532
    • Genain C. P., Cannella B., Hauser S. L., Raine C. S., Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nature Medicine 1999 5 2 170 175 2-s2.0-0032950794 10.1038/5532 (Pubitemid 29068523)
    • (1999) Nature Medicine , vol.5 , Issue.2 , pp. 170-175
    • Genain, C.P.1    Cannella, B.2    Hauser, S.L.3    Raine, C.S.4
  • 50
    • 79551695835 scopus 로고    scopus 로고
    • Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis
    • 2-s2.0-79551695835 10.1093/brain/awq350
    • Lovato L., Willis S. N., Rodig S. J., Caron T., Almendinger S. E., Howell O. W., Reynolds R., O'Connor K. C., Hafler D. A., Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis. Brain 2011 134 2 534 541 2-s2.0-79551695835 10.1093/brain/awq350
    • (2011) Brain , vol.134 , Issue.2 , pp. 534-541
    • Lovato, L.1    Willis, S.N.2    Rodig, S.J.3    Caron, T.4    Almendinger, S.E.5    Howell, O.W.6    Reynolds, R.7    O'Connor, K.C.8    Hafler, D.A.9
  • 51
    • 34249700046 scopus 로고    scopus 로고
    • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    • DOI 10.1093/brain/awm038
    • Magliozzi R., Howell O., Vora A., Serafini B., Nicholas R., Puopolo M., Reynolds R., Aloisi F., Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 2007 130 4 1089 1104 2-s2.0-34249700046 10.1093/brain/awm038 (Pubitemid 47355604)
    • (2007) Brain , vol.130 , Issue.4 , pp. 1089-1104
    • Magliozzi, R.1    Howell, O.2    Vora, A.3    Serafini, B.4    Nicholas, R.5    Puopolo, M.6    Reynolds, R.7    Aloisi, F.8
  • 52
    • 2442708947 scopus 로고    scopus 로고
    • Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
    • Serafini B., Rosicarelli B., Magliozzi R., Stigliano E., Aloisi F., Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathology 2004 14 2 164 174 2-s2.0-2442708947 (Pubitemid 38656388)
    • (2004) Brain Pathology , vol.14 , Issue.2 , pp. 164-174
    • Serafini, B.1    Rosicarelli, B.2    Magliozzi, R.3    Stigliano, E.4    Aloisi, F.5
  • 53
    • 70349577131 scopus 로고    scopus 로고
    • Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis
    • 2-s2.0-70349577131 10.1097/NEN.0b013e3181b4bf8f
    • Kooi E. J., Geurts J. J., van Horssen J., Bø L., van der Valk P., Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis. Journal of Neuropathology and Experimental Neurology 2009 68 9 1021 1028 2-s2.0-70349577131 10.1097/NEN.0b013e3181b4bf8f
    • (2009) Journal of Neuropathology and Experimental Neurology , vol.68 , Issue.9 , pp. 1021-1028
    • Kooi, E.J.1    Geurts, J.J.2    Van Horssen, J.3    Bø, L.B.4    Van Der Valk, P.5
  • 55
    • 83555178479 scopus 로고    scopus 로고
    • Th17 expansion in MS patients is counterbalanced by an expanded CD39+ regulatory T cell population during remission but not during relapse
    • Peelen E., Damoiseaux J., Smolders J., Knippenberg S., Menheere P., Tervaert J. W., Th17 expansion in MS patients is counterbalanced by an expanded CD39+ regulatory T cell population during remission but not during relapse. Journal of Neuroimmunology 2011 240-241 97 103
    • (2011) Journal of Neuroimmunology , vol.240-241 , pp. 97-103
    • Peelen, E.1    Damoiseaux, J.2    Smolders, J.3    Knippenberg, S.4    Menheere, P.5    Tervaert, J.W.6
  • 56
    • 84864431745 scopus 로고    scopus 로고
    • Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter
    • Varrin-Doyer M., Spencer C. M., Schulze-Topphoff U., Nelson P. A., Stroud R. M., Cree B. A., Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Annals of Neurology 2012 72 1 53 64
    • (2012) Annals of Neurology , vol.72 , Issue.1 , pp. 53-64
    • Varrin-Doyer, M.1    Spencer, C.M.2    Schulze-Topphoff, U.3    Nelson, P.A.4    Stroud, R.M.5    Cree, B.A.6
  • 57
    • 77953273617 scopus 로고    scopus 로고
    • Understanding the development and function of T follicular helper cells
    • 2-s2.0-77953273617 10.1038/cmi.2010.24
    • Nurieva R. I., Chung Y., Understanding the development and function of T follicular helper cells. Cellular and Molecular Immunology 2010 7 3 190 197 2-s2.0-77953273617 10.1038/cmi.2010.24
    • (2010) Cellular and Molecular Immunology , vol.7 , Issue.3 , pp. 190-197
    • Nurieva, R.I.1    Chung, Y.2
  • 58
    • 10344250945 scopus 로고    scopus 로고
    • A serum autoantibody marker of neuromyelitis optica: Distinction from multiple sclerosis
    • DOI 10.1016/S0140-6736(04)17551-X, PII S014067360417551X
    • Lennon P. V. A., Wingerchuk D. M., Kryzer T. J., Pittock S. J., Lucchinetti C. F., Fujihara K., Nakashima I., Weinshenker B. G., A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 2004 364 9451 2106 2112 2-s2.0-10344250945 10.1016/S0140-6736(04)17551-X (Pubitemid 39626806)
    • (2004) Lancet , vol.364 , Issue.9451 , pp. 2106-2112
    • Lennon, P.V.A.1    Wingerchuk, D.M.2    Kryzer, T.J.3    Pittock, S.J.4    Lucchinetti, C.F.5    Fujihara, K.6    Nakashima, I.7    Weinshenker, B.G.8
  • 60
    • 72749086379 scopus 로고    scopus 로고
    • Association of anti-Helicobacter pylori neutrophil-activating protein antibody response with anti-aquaporin-4 autoimmunity in Japanese patients with multiple sclerosis and neuromyelitis optica
    • 2-s2.0-72749086379 10.1177/1352458509348961
    • Li W., Minohara M., Piao H., Matsushita T., Masaki K., Matsuoka T., Isobe N., Su J. J., Ohyagi Y., Kira J. I., Association of anti-Helicobacter pylori neutrophil-activating protein antibody response with anti-aquaporin-4 autoimmunity in Japanese patients with multiple sclerosis and neuromyelitis optica. Multiple Sclerosis 2009 15 12 1411 1421 2-s2.0-72749086379 10.1177/1352458509348961
    • (2009) Multiple Sclerosis , vol.15 , Issue.12 , pp. 1411-1421
    • Li, W.1    Minohara, M.2    Piao, H.3    Matsushita, T.4    Masaki, K.5    Matsuoka, T.6    Isobe, N.7    Su, J.J.8    Ohyagi, Y.9    Kira, J.I.10
  • 61
    • 84867919274 scopus 로고    scopus 로고
    • Cross-immunoreactivity between bacterial aquaporin-Z and human aquaporin-4: Potential relevance to neuromyelitis optica
    • Ren Z., Wang Y., Duan T., Patel J., Liggett T., Loda E., Cross-immunoreactivity between bacterial aquaporin-Z and human aquaporin-4: potential relevance to neuromyelitis optica. Journal of Immunology 2012 189 9 4602 4611
    • (2012) Journal of Immunology , vol.189 , Issue.9 , pp. 4602-4611
    • Ren, Z.1    Wang, Y.2    Duan, T.3    Patel, J.4    Liggett, T.5    Loda, E.6
  • 62
    • 78650092261 scopus 로고    scopus 로고
    • Cytokine and chemokine profiles in neuromyelitis optica: Significance of interleukin-6
    • 2-s2.0-78650092261 10.1177/1352458510379247
    • Uzawa A., Mori M., Arai K., Sato Y., Hayakawa S., Masuda S., Taniguchi J., Kuwabara S., Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6. Multiple Sclerosis 2010 16 12 1443 1452 2-s2.0-78650092261 10.1177/1352458510379247
    • (2010) Multiple Sclerosis , vol.16 , Issue.12 , pp. 1443-1452
    • Uzawa, A.1    Mori, M.2    Arai, K.3    Sato, Y.4    Hayakawa, S.5    Masuda, S.6    Taniguchi, J.7    Kuwabara, S.8
  • 63
    • 80052082720 scopus 로고    scopus 로고
    • Interleukin-17-secreting T cells in neuromyelitis optica and multiple sclerosis during relapse
    • Wang H. H., Dai Y. Q., Qiu W., Lu Z. Q., Peng F. H., Wang Y. G., Interleukin-17-secreting T cells in neuromyelitis optica and multiple sclerosis during relapse. Journal of Clinical Neuroscience 2011 18 10 1313 1317
    • (2011) Journal of Clinical Neuroscience , vol.18 , Issue.10 , pp. 1313-1317
    • Wang, H.H.1    Dai, Y.Q.2    Qiu, W.3    Lu, Z.Q.4    Peng, F.H.5    Wang, Y.G.6
  • 64
    • 84861138201 scopus 로고    scopus 로고
    • Aquaporin 4 and neuromyelitis optica
    • Papadopoulos M. C., Verkman A. S., Aquaporin 4 and neuromyelitis optica. Lancet Neurology 2012 11 6 535 544
    • (2012) Lancet Neurology , vol.11 , Issue.6 , pp. 535-544
    • Papadopoulos, M.C.1    Verkman, A.S.2
  • 65
    • 77955456303 scopus 로고    scopus 로고
    • Interferon beta treatment in neuromyelitis optica: Increase in relapses and aquaporin 4 antibody titers
    • 2-s2.0-77955456303 10.1001/archNeurology.2010.188
    • Palace J., Leite M. I., Nairne A., Vincent A., Interferon beta treatment in neuromyelitis optica: increase in relapses and aquaporin 4 antibody titers. Archives of Neurology 2010 67 8 1016 1017 2-s2.0-77955456303 10.1001/archNeurology.2010.188
    • (2010) Archives of Neurology , vol.67 , Issue.8 , pp. 1016-1017
    • Palace, J.1    Leite, M.I.2    Nairne, A.3    Vincent, A.4
  • 67
    • 77955665655 scopus 로고    scopus 로고
    • Overlapping and distinct mechanisms of action of multiple sclerosis therapies
    • 2-s2.0-77955665655 10.1016/j.clineuro.2010.05.002
    • Graber J. J., McGraw C. A., Kimbrough D., Dhib-Jalbut S., Overlapping and distinct mechanisms of action of multiple sclerosis therapies. Clinical Neurology and Neurosurgery 2010 112 7 583 591 2-s2.0-77955665655 10.1016/j.clineuro.2010.05.002
    • (2010) Clinical Neurology and Neurosurgery , vol.112 , Issue.7 , pp. 583-591
    • Graber, J.J.1    McGraw, C.A.2    Kimbrough, D.3    Dhib-Jalbut, S.4
  • 68
    • 84856805188 scopus 로고    scopus 로고
    • + regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis
    • + regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis. Journal of Neuroimmunology 2012 242 1-2 39 46
    • (2012) Journal of Neuroimmunology , vol.242 , Issue.1-2 , pp. 39-46
    • Chen, M.1    Chen, G.2    Deng, S.3    Liu, X.4    Hutton, G.J.5
  • 71
    • 79953890862 scopus 로고    scopus 로고
    • Glatiramer acetate in the treatment of multiple sclerosis: Emerging concepts regarding its mechanism of action
    • 2-s2.0-79953890862 10.2165/11588120-000000000-00000
    • Lalive P. H., Neuhaus O., Benkhoucha M., Burger D., Hohlfeld R., Zamvil S. S., Weber M. S., Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action. CNS Drugs 2011 25 5 401 414 2-s2.0-79953890862 10.2165/11588120-000000000-00000
    • (2011) CNS Drugs , vol.25 , Issue.5 , pp. 401-414
    • Lalive, P.H.1    Neuhaus, O.2    Benkhoucha, M.3    Burger, D.4    Hohlfeld, R.5    Zamvil, S.S.6    Weber, M.S.7
  • 74
    • 79957973246 scopus 로고    scopus 로고
    • Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients
    • 2-s2.0-79957973246 10.1016/j.jneuroim.2011.02.010
    • Skarica M., Eckstein C., Whartenby K. A., Calabresi P. A., Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients. Journal of Neuroimmunology 2011 235 1-2 70 76 2-s2.0-79957973246 10.1016/j.jneuroim.2011.02.010
    • (2011) Journal of Neuroimmunology , vol.235 , Issue.1-2 , pp. 70-76
    • Skarica, M.1    Eckstein, C.2    Whartenby, K.A.3    Calabresi, P.A.4
  • 76
    • 84872289860 scopus 로고    scopus 로고
    • A genetic variant of the anti-apoptotic protein Akt predicts natalizumab-induced lymphocytosis and post-natalizumab multiple sclerosis reactivation
    • Rossi S., Motta C., Studer V., Monteleone F., De Chiara V., Buttari F., A genetic variant of the anti-apoptotic protein Akt predicts natalizumab-induced lymphocytosis and post-natalizumab multiple sclerosis reactivation. Multiple Sclerosis 2013 19 1 59 68
    • (2013) Multiple Sclerosis , vol.19 , Issue.1 , pp. 59-68
    • Rossi, S.1    Motta, C.2    Studer, V.3    Monteleone, F.4    De Chiara, V.5    Buttari, F.6
  • 77
    • 84865483379 scopus 로고    scopus 로고
    • Natalizumab-associated progressive multifocal leukoencephalopathy
    • Mancini N., Clementi M., Burioni R., Natalizumab-associated progressive multifocal leukoencephalopathy. New England Journal of Medicine 2012 367 9 871 872
    • (2012) New England Journal of Medicine , vol.367 , Issue.9 , pp. 871-872
    • Mancini, N.1    Clementi, M.2    Burioni, R.3
  • 78
    • 84873185064 scopus 로고    scopus 로고
    • Natalizumab therapy for multiple sclerosis
    • Chataway J., Miller D. H., Natalizumab therapy for multiple sclerosis. Neurotherapeutics 2013 10 1 19 28
    • (2013) Neurotherapeutics , vol.10 , Issue.1 , pp. 19-28
    • Chataway, J.1    Miller, D.H.2
  • 79
    • 15944382687 scopus 로고    scopus 로고
    • Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy
    • Shelburne S. A., Visnegarwala F., Darcourt J., Graviss E. A., Giordano T. P., White A. C., Hamill R. J., Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy. AIDS 2005 19 4 399 406 2-s2.0-15944382687 (Pubitemid 40446186)
    • (2005) AIDS , vol.19 , Issue.4 , pp. 399-406
    • Shelburne, S.A.1    Visnegarwala, F.2    Darcourt, J.3    Graviss, E.A.4    Giordano, T.P.5    White Jr., A.C.6    Hamill, R.J.7
  • 81
    • 78449244305 scopus 로고    scopus 로고
    • Neurologyogical S1P signaling as an emerging mechanism of action of oral FTY720 (Fingolimod) in multiple sclerosis
    • 2-s2.0-78449244305 10.1007/s12272-010-1008-5
    • Lee C. W., Choi J. W., Chun J., Neurologyogical S1P signaling as an emerging mechanism of action of oral FTY720 (Fingolimod) in multiple sclerosis. Archives of Pharmacal Research 2010 33 10 1567 1574 2-s2.0-78449244305 10.1007/s12272-010-1008-5
    • (2010) Archives of Pharmacal Research , vol.33 , Issue.10 , pp. 1567-1574
    • Lee, C.W.1    Choi, J.W.2    Chun, J.3
  • 83
    • 84871309340 scopus 로고    scopus 로고
    • Simultaneous Pml-Iris after discontinuation of natalizumab in a patient with MS
    • Marousi S., Travasarou M., Karageorgiou C. E., Gheuens S., Koralnik I. J., Simultaneous Pml-Iris after discontinuation of natalizumab in a patient with MS. Neurology 2012 79 21 2160
    • (2012) Neurology , vol.79 , Issue.21 , pp. 2160
    • Marousi, S.1    Travasarou, M.2    Karageorgiou, C.E.3    Gheuens, S.4    Koralnik, I.J.5
  • 84
    • 70349333237 scopus 로고    scopus 로고
    • The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo
    • 2-s2.0-70349333237 10.4049/jimmunol.0901011
    • Wolf A. M., Eller K., Zeiser R., Dürr C., Gerlach U. V., Sixt M., Markut L., Gastl G., Rosenkranz A. R., Wolf D., The sphingosine 1-phosphate receptor agonist FTY720 potently inhibits regulatory T cell proliferation in vitro and in vivo. Journal of Immunology 2009 183 6 3751 3760 2-s2.0-70349333237 10.4049/jimmunol.0901011
    • (2009) Journal of Immunology , vol.183 , Issue.6 , pp. 3751-3760
    • Wolf, A.M.1    Eller, K.2    Zeiser, R.3    Dürr, C.4    Gerlach, U.V.5    Sixt, M.6    Markut, L.7    Gastl, G.8    Rosenkranz, A.R.9    Wolf, D.10
  • 86
    • 0029058317 scopus 로고
    • The major histocompatibility complex in man
    • 2-s2.0-0029058317
    • Buc M., The major histocompatibility complex in man. Folia Biologica 1995 41 3-4 119 122 2-s2.0-0029058317
    • (1995) Folia Biologica , vol.41 , Issue.3-4 , pp. 119-122
    • Buc, M.1
  • 88
    • 84856297433 scopus 로고    scopus 로고
    • Treatment of multiple sclerosis with anti-CD20 antibodies
    • Barun B., Bar-Or A., Treatment of multiple sclerosis with anti-CD20 antibodies. Clinical Immunology 2012 142 1 31 37
    • (2012) Clinical Immunology , vol.142 , Issue.1 , pp. 31-37
    • Barun, B.1    Bar-Or, A.2
  • 89
    • 84859376769 scopus 로고    scopus 로고
    • A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand
    • Ray A., Basu S., Williams C. B., Salzman N. H., Dittel B. N., A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand. Journal of Immunology 2012 188 7 3188 3198
    • (2012) Journal of Immunology , vol.188 , Issue.7 , pp. 3188-3198
    • Ray, A.1    Basu, S.2    Williams, C.B.3    Salzman, N.H.4    Dittel, B.N.5
  • 90
    • 0018949401 scopus 로고
    • Characterization of a human B lymphocyte-specific antigen
    • Stashenko P., Nadler L. M., Hardy R., Schlossman S. F., Characterization of a human B lymphocyte-specific antigen. Journal of Immunology 1980 125 4 1678 1685 2-s2.0-0018949401 (Pubitemid 10018582)
    • (1980) Journal of Immunology , vol.125 , Issue.4 , pp. 1678-1685
    • Stashenko, P.1    Nadler, L.M.2    Hardy, R.3    Schlossman, S.F.4
  • 92
    • 0028870425 scopus 로고
    • Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes
    • 2-s2.0-0028870425
    • Rowan W. C., Hale G., Tite J. P., Brett S. J., Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes. International Immunology 1995 7 1 69 77 2-s2.0-0028870425
    • (1995) International Immunology , vol.7 , Issue.1 , pp. 69-77
    • Rowan, W.C.1    Hale, G.2    Tite, J.P.3    Brett, S.J.4
  • 93
    • 0034033048 scopus 로고    scopus 로고
    • The CD45 tyrosine phosphatase regulates Campath-1H (CD52)-induced TCR-dependent signal transduction in human T cells
    • Hederer R. A., Guntermann C., Miller N., Nagy P., Szollosi J., Damjanovich S., Hale G., Alexander D. R., The CD45 tyrosine phosphatase regulates Campath-1H (CD52)-induced TCR-dependent signal transduction in human T cells. International Immunology 2000 12 4 505 516 2-s2.0-0034033048 (Pubitemid 30199356)
    • (2000) International Immunology , vol.12 , Issue.4 , pp. 505-516
    • Hederer, R.A.1    Guntermann, C.2    Miller, N.3    Nagy, P.4    Szollosi, J.5    Damjanovich, S.6    Hale, G.7    Alexander, D.R.8
  • 94
  • 96
    • 77249114139 scopus 로고    scopus 로고
    • B-Cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis
    • 2-s2.0-77249114139 10.1007/s10875-009-9327-3
    • Thompson S. A. J., Jones J. L., Cox A. L., Compston D. A. S., Coles A. J., B-Cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis. Journal of Clinical Immunology 2010 30 1 99 105 2-s2.0-77249114139 10.1007/s10875-009-9327-3
    • (2010) Journal of Clinical Immunology , vol.30 , Issue.1 , pp. 99-105
    • Thompson, S.A.J.1    Jones, J.L.2    Cox, A.L.3    Compston, D.A.S.4    Coles, A.J.5
  • 97
    • 0033552391 scopus 로고    scopus 로고
    • Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis
    • DOI 10.1016/S0140-6736(99)02429-0
    • Coles A. J., Wing M., Smith S., Coraddu F., Greer S., Taylor C., Weetman A., Hale G., Chatterjee V. K., Waldmann H., Compston A., Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis. Lancet 1999 354 9191 1691 1695 2-s2.0-0033552391 10.1016/S0140-6736(99)02429-0 (Pubitemid 29533060)
    • (1999) Lancet , vol.354 , Issue.9191 , pp. 1691-1695
    • Coles, A.J.1    Wing, M.2    Smith, S.3    Coraddu, F.4    Greer, S.5    Taylor, C.6    Weetman, A.7    Hale, G.8    Chatterjee, V.K.9    Waldmann, H.10    Compston, A.11
  • 99
    • 84856252354 scopus 로고    scopus 로고
    • Immune mechanisms of new therapeutic strategies in multiple sclerosis-A focus on alemtuzumab
    • Klotz L., Meuth S. G., Wiendl H., Immune mechanisms of new therapeutic strategies in multiple sclerosis-A focus on alemtuzumab. Clinical Immunology 2012 142 1 25 30
    • (2012) Clinical Immunology , vol.142 , Issue.1 , pp. 25-30
    • Klotz, L.1    Meuth, S.G.2    Wiendl, H.3
  • 100
    • 84873145686 scopus 로고    scopus 로고
    • Daclizumab therapy for multiple sclerosis
    • Bielekova B., Daclizumab therapy for multiple sclerosis. Neurotherapeutics 2013 10 1 55 67
    • (2013) Neurotherapeutics , vol.10 , Issue.1 , pp. 55-67
    • Bielekova, B.1
  • 101
    • 84863410319 scopus 로고    scopus 로고
    • Anti-CD25 (daclizumab) monoclonal antibody therapy in relapsing-remitting multiple sclerosis
    • Martin R., Anti-CD25 (daclizumab) monoclonal antibody therapy in relapsing-remitting multiple sclerosis. Clinical Immunology 2012 142 1 9 14
    • (2012) Clinical Immunology , vol.142 , Issue.1 , pp. 9-14
    • Martin, R.1
  • 102
    • 44849118898 scopus 로고    scopus 로고
    • Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation
    • 2-s2.0-44849118898 10.1002/eji.200738108
    • Brusko T., Bluestone J., Clinical application of regulatory T cells for treatment of type 1 diabetes and transplantation. European Journal of Immunology 2008 38 4 931 934 2-s2.0-44849118898 10.1002/eji.200738108
    • (2008) European Journal of Immunology , vol.38 , Issue.4 , pp. 931-934
    • Brusko, T.1    Bluestone, J.2
  • 105
    • 79955678019 scopus 로고    scopus 로고
    • Biomarkers of disease activity in multiple sclerosis
    • 2-s2.0-79955678019 10.1016/j.jns.2011.03.026
    • Graber J. J., Dhib-Jalbut S., Biomarkers of disease activity in multiple sclerosis. Journal of the Neurological Sciences 2011 305 1-2 1 10 2-s2.0-79955678019 10.1016/j.jns.2011.03.026
    • (2011) Journal of the Neurological Sciences , vol.305 , Issue.1-2 , pp. 1-10
    • Graber, J.J.1    Dhib-Jalbut, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.