PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

Journal of Experimental Medicine

Volumn 210, Issue 4, 2013, Pages 757-774

  Zinselmeyer, Bernd H ^a   Heydari, Sara ^a   Sacristán, Catarina ^b   Nayak, Debasis ^a   Cammer, Michael ^b   Herz, Jasmin ^a   Cheng, Xiaoxiao ^c   Davis, Simon J ^c   Dustin, Michael L ^b   McGavern, Dorian B ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; CD274 PROTEIN, MOUSE; DIFFERENTIATION ANTIGEN; PD 1 ANTIGEN, MOUSE; PD-1 ANTIGEN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MOTILITY; CYTOKINE PRODUCTION; EFFECTOR CELL; IMMUNOLOGICAL SYNAPSE; IMMUNOREGULATION; IN VIVO STUDY; INTRACELLULAR SIGNALING; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; VIRUS LOAD; ANIMAL; CELL MOTION; CELLULAR IMMUNITY; GENETICS; IMMUNOLOGY; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE MUTANT;

ANIMALS; ANTIGENS, CD274; ANTIGENS, DIFFERENTIATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; IMMUNITY, CELLULAR; INTERFERON-GAMMA; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, KNOCKOUT; VIRAL LOAD;

MLCS; MLOWN;

EID: 84878625979     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121416     Document Type: Article

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