메뉴 건너뛰기




Volumn 330, Issue 1-2, 2013, Pages 18-26

Mitochondria, motor neurons and aging

Author keywords

Aging; Apoptosis; Calcium; Mitochondria; Motor neuron; Swelling

Indexed keywords

CALCIUM; CASPASE 3; CYTOCHROME C; DYNEIN ADENOSINE TRIPHOSPHATASE;

EID: 84878597712     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2013.03.019     Document Type: Article
Times cited : (47)

References (52)
  • 1
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • M.T. Lin, and M.F. Beal Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Nature 443 2006 787 795
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 2
    • 60349108806 scopus 로고    scopus 로고
    • Mitochondrial medicine for aging and neurodegenerative diseases
    • P.H. Reddy Mitochondrial medicine for aging and neurodegenerative diseases Neuromolecular Med 10 2008 291 315
    • (2008) Neuromolecular Med , vol.10 , pp. 291-315
    • Reddy, P.H.1
  • 3
    • 34347353834 scopus 로고    scopus 로고
    • Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies
    • R.H. Swerdlow Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies J Neurosci Res 85 2007 3416 3428
    • (2007) J Neurosci Res , vol.85 , pp. 3416-3428
    • Swerdlow, R.H.1
  • 4
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic & degenerative diseases, aging and cancer: A dawn for evolutionary medicine
    • D.C. Wallace A mitochondrial paradigm of metabolic & degenerative diseases, aging and cancer: a dawn for evolutionary medicine Annu Rev Genet 39 2005 359 407
    • (2005) Annu Rev Genet , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 5
    • 77952499066 scopus 로고    scopus 로고
    • Programmed cell death and apoptosis in aging and life span regulation
    • J. Shen, and J. Tower Programmed cell death and apoptosis in aging and life span regulation Discov Med 8 2009 223 226
    • (2009) Discov Med , vol.8 , pp. 223-226
    • Shen, J.1    Tower, J.2
  • 6
    • 0034647003 scopus 로고    scopus 로고
    • Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
    • M. Li, V.O. Ona, C. Guegan, M. Chen, V. Jackson-Lewis, and L.J. Andrews Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model Science 288 2000 335 339
    • (2000) Science , vol.288 , pp. 335-339
    • Li, M.1    Ona, V.O.2    Guegan, C.3    Chen, M.4    Jackson-Lewis, V.5    Andrews, L.J.6
  • 7
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • R.M. Friedlander Apoptosis and caspases in neurodegenerative diseases N Engl J Med 348 2003 1365 1375
    • (2003) N Engl J Med , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 8
    • 2442621492 scopus 로고    scopus 로고
    • Role of AIF in caspase-dependent and caspase-independent cell death
    • S.P. Cregan, V.L. Dawson, and R.S. Slack Role of AIF in caspase-dependent and caspase-independent cell death Oncogene 23 2004 2785 2796
    • (2004) Oncogene , vol.23 , pp. 2785-2796
    • Cregan, S.P.1    Dawson, V.L.2    Slack, R.S.3
  • 11
    • 33749265862 scopus 로고    scopus 로고
    • Formation of elongated giant mitochondria in DFO-induced cellular senescence: Involvement of enhanced fusion process through modulation of Fis1
    • Y.S. Yoon, D.S. Yoon, I.K. Lim, S.H. Yoon, H.Y. Chung, and M. Rojo Formation of elongated giant mitochondria in DFO-induced cellular senescence: Involvement of enhanced fusion process through modulation of Fis1 J Cell Physiol 209 2006 468 480
    • (2006) J Cell Physiol , vol.209 , pp. 468-480
    • Yoon, Y.S.1    Yoon, D.S.2    Lim, I.K.3    Yoon, S.H.4    Chung, H.Y.5    Rojo, M.6
  • 13
    • 4544280654 scopus 로고    scopus 로고
    • Mitochondria and aging: A role for the permeability transition?
    • M. Crompton Mitochondria and aging: a role for the permeability transition? Aging Cell 3 2004 3 6
    • (2004) Aging Cell , vol.3 , pp. 3-6
    • Crompton, M.1
  • 14
    • 25444474703 scopus 로고    scopus 로고
    • Mitochondria take center stage in aging and neurodegeneration
    • M.F. Beal Mitochondria take center stage in aging and neurodegeneration Ann Neurol 58 2005 495 505
    • (2005) Ann Neurol , vol.58 , pp. 495-505
    • Beal, M.F.1
  • 15
    • 73349132395 scopus 로고    scopus 로고
    • Role of mitochondria in neurodegenerative diseases: Mitochondria as a therapeutic target in Alzheimer's disease
    • P.H. Reddy Role of mitochondria in neurodegenerative diseases: mitochondria as a therapeutic target in Alzheimer's disease CNS Spectr 14 2009 8 13
    • (2009) CNS Spectr , vol.14 , pp. 8-13
    • Reddy, P.H.1
  • 17
    • 0039251419 scopus 로고    scopus 로고
    • Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase
    • A.G. Estévez, J.P. Crow, J.B. Sampson, C. Reiter, Y. Zhuang, and G.J. Richardson Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase Science 24 1999 2498 2500
    • (1999) Science , vol.24 , pp. 2498-2500
    • Estévez, A.G.1    Crow, J.P.2    Sampson, J.B.3    Reiter, C.4    Zhuang, Y.5    Richardson, G.J.6
  • 18
    • 0029671220 scopus 로고    scopus 로고
    • Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis
    • M. Wiedau-Pazos, J.J. Goto, S. Rabizadeh, E.D. Gralla, J.A. Roe, and M.K. Lee Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis Science 271 1996 515 518
    • (1996) Science , vol.271 , pp. 515-518
    • Wiedau-Pazos, M.1    Goto, J.J.2    Rabizadeh, S.3    Gralla, E.D.4    Roe, J.A.5    Lee, M.K.6
  • 19
    • 17444427385 scopus 로고    scopus 로고
    • Increased production of reactive oxygen species contributes to motor neuron death in a compression mouse model of spinal cord injury
    • W. Xu, L. Chi, R. Xu, Y. Ke, C. Luo, and J. Cai Increased production of reactive oxygen species contributes to motor neuron death in a compression mouse model of spinal cord injury Spinal Cord 43 2005 204 213
    • (2005) Spinal Cord , vol.43 , pp. 204-213
    • Xu, W.1    Chi, L.2    Xu, R.3    Ke, Y.4    Luo, C.5    Cai, J.6
  • 20
    • 77952312535 scopus 로고    scopus 로고
    • Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration
    • C.J. Youngmok, M.S. Lustgarten, Y. Liu, F.L. Muller, A. Bhattacharya, and H. Liang Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration FASEB J 24 2010 1376 1390
    • (2010) FASEB J , vol.24 , pp. 1376-1390
    • Youngmok, C.J.1    Lustgarten, M.S.2    Liu, Y.3    Muller, F.L.4    Bhattacharya, A.5    Liang, H.6
  • 21
    • 16844366080 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and its role in motor neuron degeneration in ALS
    • G. Manfredi, and Z. Xu Mitochondrial dysfunction and its role in motor neuron degeneration in ALS Mitochondrion 5 2005 77 87
    • (2005) Mitochondrion , vol.5 , pp. 77-87
    • Manfredi, G.1    Xu, Z.2
  • 22
    • 0034175513 scopus 로고    scopus 로고
    • Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases
    • D. Frey, C. Schneider, L. Xu, J. Borg, W. Spooren, and P. Caroni Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases J Neurosci 20 2000 2534 2542
    • (2000) J Neurosci , vol.20 , pp. 2534-2542
    • Frey, D.1    Schneider, C.2    Xu, L.3    Borg, J.4    Spooren, W.5    Caroni, P.6
  • 25
    • 0037734370 scopus 로고    scopus 로고
    • Mutations in dynein link motor neuron degeneration to defects in retrograde transport
    • M. Hafezparast, R. Klocke, C. Ruhrberg, A. Marquardt, A. Ahmad-Annuar, and S. Bowen Mutations in dynein link motor neuron degeneration to defects in retrograde transport Science 300 2003 808 812
    • (2003) Science , vol.300 , pp. 808-812
    • Hafezparast, M.1    Klocke, R.2    Ruhrberg, C.3    Marquardt, A.4    Ahmad-Annuar, A.5    Bowen, S.6
  • 26
    • 0037198698 scopus 로고    scopus 로고
    • Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive deterioration
    • B. LaMonte, K.E. Wallace, B.A. Holloway, S.S. Shelly, J. Ascano, and M. Tokito Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive deterioration Neuron 34 2002 715 727
    • (2002) Neuron , vol.34 , pp. 715-727
    • Lamonte, B.1    Wallace, K.E.2    Holloway, B.A.3    Shelly, S.S.4    Ascano, J.5    Tokito, M.6
  • 30
    • 39149122810 scopus 로고    scopus 로고
    • Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease
    • P.H. Reddy, and M.F. Beal Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease Trends Mol Med 14 2008 45 54
    • (2008) Trends Mol Med , vol.14 , pp. 45-54
    • Reddy, P.H.1    Beal, M.F.2
  • 31
    • 50949127216 scopus 로고    scopus 로고
    • Correlated light and electron microscopy illuminates the role of mitochondrial inner membrane remodeling during apoptosis
    • T.G. Frey, and M.G. Sun Correlated light and electron microscopy illuminates the role of mitochondrial inner membrane remodeling during apoptosis Biochim Biophys Acta 1777 2008 847 852
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 847-852
    • Frey, T.G.1    Sun, M.G.2
  • 32
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • D.R. Green, and J.C. Reed Mitochondria and apoptosis Science 281 1998 309 1312
    • (1998) Science , vol.281 , pp. 309-1312
    • Green, D.R.1    Reed, J.C.2
  • 33
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • G. Kroemer, and J.C. Reed Mitochondrial control of cell death Nat Med 6 2000 513 519
    • (2000) Nat Med , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 35
    • 0344348821 scopus 로고    scopus 로고
    • Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1 mediated caspase-9 activation and apoptosis
    • Y. Hu, M.A. Benedict, L. Ding, and G. Nunez Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1 mediated caspase-9 activation and apoptosis EMBO J 18 1999 3586 3595
    • (1999) EMBO J , vol.18 , pp. 3586-3595
    • Hu, Y.1    Benedict, M.A.2    Ding, L.3    Nunez, G.4
  • 36
    • 0033573020 scopus 로고    scopus 로고
    • Caspase-9 and Apaf-1 form an active holoenzyme
    • J. Rodriguez, and Y. Lazebnik Caspase-9 and Apaf-1 form an active holoenzyme Genes Dev 13 1999 3179 3184
    • (1999) Genes Dev , vol.13 , pp. 3179-3184
    • Rodriguez, J.1    Lazebnik, Y.2
  • 37
    • 0036187036 scopus 로고    scopus 로고
    • Three-dimensional structure of the apoptosome: Implications for assembly
    • D. Acehan, X. Jiang, D.G. Morgan, J.E. Heuser, X. Wang, and C.W. Akey Three-dimensional structure of the apoptosome: implications for assembly Mol Cell 9 2002 423 432
    • (2002) Mol Cell , vol.9 , pp. 423-432
    • Acehan, D.1    Jiang, X.2    Morgan, D.G.3    Heuser, J.E.4    Wang, X.5    Akey, C.W.6
  • 38
    • 33747508562 scopus 로고    scopus 로고
    • Caspase-3 immunoreactivity in different cortical areas of young and aging macaque (Macaca mulatta) monkeys
    • A. Zhang, D.E. Lorke, Wu Sheng-Xi, and D.T. Yew Caspase-3 immunoreactivity in different cortical areas of young and aging macaque (Macaca mulatta) monkeys Neurosignals 15 2006 64 73
    • (2006) Neurosignals , vol.15 , pp. 64-73
    • Zhang, A.1    Lorke, D.E.2    Sheng-Xi, W.3    Yew, D.T.4
  • 39
    • 21544458763 scopus 로고    scopus 로고
    • Axonal dynactin p150 Glued transports caspase-8 to drive retrograde olfactory receptor neuron apoptosis
    • C. Carson, M. Saleh, F.W. Fung, D.W. Nicholson, and A.J. Roskams Axonal dynactin p150 Glued transports caspase-8 to drive retrograde olfactory receptor neuron apoptosis J Neurosci 25 2005 6092 6104
    • (2005) J Neurosci , vol.25 , pp. 6092-6104
    • Carson, C.1    Saleh, M.2    Fung, F.W.3    Nicholson, D.W.4    Roskams, A.J.5
  • 40
    • 0037686243 scopus 로고    scopus 로고
    • Megamitochondria formation - Physiology and pathology
    • T. Wakabayashi Megamitochondria formation - physiology and pathology J Cell Mol Med 6 2002 497 538
    • (2002) J Cell Mol Med , vol.6 , pp. 497-538
    • Wakabayashi, T.1
  • 42
    • 68649104009 scopus 로고    scopus 로고
    • Mitochondrial calcium function and dysfunction in the central nervous system
    • D.G. Nicholls Mitochondrial calcium function and dysfunction in the central nervous system BBA - Bioenergetics 1787 2009 1416 1424
    • (2009) BBA - Bioenergetics , vol.1787 , pp. 1416-1424
    • Nicholls, D.G.1
  • 43
    • 34547457567 scopus 로고    scopus 로고
    • Calcium-induced precipitate formation in brain mitochondria: Composition, calcium capacity, and retention
    • T. Kristian, N.B. Pivovarova, G. Fiskum, and S.B. Andrews Calcium-induced precipitate formation in brain mitochondria: composition, calcium capacity, and retention J Neurochem 102 2007 1346 1356
    • (2007) J Neurochem , vol.102 , pp. 1346-1356
    • Kristian, T.1    Pivovarova, N.B.2    Fiskum, G.3    Andrews, S.B.4
  • 44
    • 3042595335 scopus 로고    scopus 로고
    • Excitotoxic calcium overload in a subpopulation of mitochondria triggers delayed death in hippocampal neurons
    • N.B. Pivarova, H.V. Nguyen, C.A. Winters, C.A. Brantner, C.L. Smith, and S.B. Andrews Excitotoxic calcium overload in a subpopulation of mitochondria triggers delayed death in hippocampal neurons J Neurosci 24 2004 5611 5622
    • (2004) J Neurosci , vol.24 , pp. 5611-5622
    • Pivarova, N.B.1    Nguyen, H.V.2    Winters, C.A.3    Brantner, C.A.4    Smith, C.L.5    Andrews, S.B.6
  • 46
    • 0033572328 scopus 로고    scopus 로고
    • Quantitative energy-dispersive X-ray microanalysis of calcium dynamics in cell suspensions during stimulation on a subsecond time scale: Preparative and analytical aspects as exemplified with paramecium cells
    • M. Hardt, and H. Plattner Quantitative energy-dispersive X-ray microanalysis of calcium dynamics in cell suspensions during stimulation on a subsecond time scale: preparative and analytical aspects as exemplified with paramecium cells J Struct Biol 128 1999 187 199
    • (1999) J Struct Biol , vol.128 , pp. 187-199
    • Hardt, M.1    Plattner, H.2
  • 47
    • 34248194944 scopus 로고    scopus 로고
    • New insights into mitochondrial fusion
    • Y. Zhang, and D.C. Chan New insights into mitochondrial fusion FEBS Lett 581 2007 2168 2173
    • (2007) FEBS Lett , vol.581 , pp. 2168-2173
    • Zhang, Y.1    Chan, D.C.2
  • 48
    • 10644296253 scopus 로고    scopus 로고
    • Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis
    • R. Sugioka, S. Shimizu, and Y. Tsujimoto Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis J Biol Chem 279 2004 52726 52734
    • (2004) J Biol Chem , vol.279 , pp. 52726-52734
    • Sugioka, R.1    Shimizu, S.2    Tsujimoto, Y.3
  • 49
    • 21644455319 scopus 로고    scopus 로고
    • Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization
    • M. Neuspiel, R. Zunino, S. Gangaraju, P. Rippstein, and H. McBride Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization J Biol Chem 280 2005 25060 25070
    • (2005) J Biol Chem , vol.280 , pp. 25060-25070
    • Neuspiel, M.1    Zunino, R.2    Gangaraju, S.3    Rippstein, P.4    McBride, H.5
  • 50
    • 71849118179 scopus 로고
    • Mitochondrial dysfunction in amyotrophic lateral sclerosis
    • P. Shi, J. Gal, D.M. Kwinter, X. Liu, and H. Zhu Mitochondrial dysfunction in amyotrophic lateral sclerosis BBA-Mol Basis Dis 2010 1802 45 51
    • (1802) BBA-Mol Basis Dis , vol.2010 , pp. 45-51
    • Shi, P.1    Gal, J.2    Kwinter, D.M.3    Liu, X.4    Zhu, H.5
  • 51
    • 65549128133 scopus 로고    scopus 로고
    • Muscle mitochondrial uncopling dismantles neuromuscular junction and triggers distal degeneration of motor neurons
    • L. Dupuis, J.L. Gonzalez de Aguila, A. Echaniz-Laguna, J. Eschbach, R. Frédérique, and H. Oudart Muscle mitochondrial uncopling dismantles neuromuscular junction and triggers distal degeneration of motor neurons PLoS One 4 2009 e5390
    • (2009) PLoS One , vol.4 , pp. 5390
    • Dupuis, L.1    Gonzalez De Aguila, J.L.2    Echaniz-Laguna, A.3    Eschbach, J.4    Frédérique, R.5    Oudart, H.6
  • 52
    • 84863068365 scopus 로고    scopus 로고
    • Early detachment of neuromuscular junction proteins in ALS mice with SODG93A mutation
    • H. Narai, Y. Manabe, M. Nagai, I. Pagano, Y. Ohta, and T. Murakami Early detachment of neuromuscular junction proteins in ALS mice with SODG93A mutation Neurol Int 1 2009 57 60
    • (2009) Neurol Int , vol.1 , pp. 57-60
    • Narai, H.1    Manabe, Y.2    Nagai, M.3    Pagano, I.4    Ohta, Y.5    Murakami, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.