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Volumn 84, Issue 2, 2013, Pages 394-400

In vitro and ex vivo models of human asthma

Author keywords

Asthma; Bronchial epithelium; In vitro models; Inflammation; Remodelling

Indexed keywords

MONTELUKAST; PEPTIDOLEUKOTRIENE; PRANLUKAST; ZAFIRLUKAST; ZILEUTON;

EID: 84878274373     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.12.014     Document Type: Article
Times cited : (61)

References (111)
  • 3
    • 58849124607 scopus 로고    scopus 로고
    • The Brussels declaration: The need for change in asthma management
    • S. Holgate The Brussels declaration: the need for change in asthma management Eur. Respir. J. 32 6 2008 1433 1442
    • (2008) Eur. Respir. J. , vol.32 , Issue.6 , pp. 1433-1442
    • Holgate, S.1
  • 4
    • 48249085691 scopus 로고    scopus 로고
    • Cluster analysis and clinical asthma phenotypes
    • P. Haldar Cluster analysis and clinical asthma phenotypes Am. J. Respir. Crit. Care Med. 178 3 2008 218 224
    • (2008) Am. J. Respir. Crit. Care Med. , vol.178 , Issue.3 , pp. 218-224
    • Haldar, P.1
  • 5
    • 84862024217 scopus 로고    scopus 로고
    • Untangling asthma phenotypes and endotypes
    • I. Agache Untangling asthma phenotypes and endotypes Allergy 67 7 2012 835 846
    • (2012) Allergy , vol.67 , Issue.7 , pp. 835-846
    • Agache, I.1
  • 6
    • 79959363586 scopus 로고    scopus 로고
    • Human asthma phenotypes: From the clinic, to cytokines, and back again
    • N.R. Bhakta, and P.G. Woodruff Human asthma phenotypes: from the clinic, to cytokines, and back again Immunol. Rev. 242 1 2011 220 232
    • (2011) Immunol. Rev. , vol.242 , Issue.1 , pp. 220-232
    • Bhakta, N.R.1    Woodruff, P.G.2
  • 8
    • 64649100473 scopus 로고    scopus 로고
    • Diagnostic and therapeutic value of airway challenges in asthma
    • D.W. Cockcroft, and B.E. Davis Diagnostic and therapeutic value of airway challenges in asthma Curr. Allergy Asthma Rep. 9 3 2009 247 253
    • (2009) Curr. Allergy Asthma Rep. , vol.9 , Issue.3 , pp. 247-253
    • Cockcroft, D.W.1    Davis, B.E.2
  • 9
    • 79955022468 scopus 로고    scopus 로고
    • Exhaled nitric oxide in asthma in adults: The end is the beginning?
    • K. Kostikas Exhaled nitric oxide in asthma in adults: the end is the beginning? Curr. Med. Chem. 18 10 2011 1423 1431
    • (2011) Curr. Med. Chem. , vol.18 , Issue.10 , pp. 1423-1431
    • Kostikas, K.1
  • 10
    • 70349241725 scopus 로고    scopus 로고
    • Inflammatory phenotypes in adult asthma: Clinical applications
    • P.G. Gibson Inflammatory phenotypes in adult asthma: clinical applications Clin. Respir. J. 3 4 2009 198 206
    • (2009) Clin. Respir. J. , vol.3 , Issue.4 , pp. 198-206
    • Gibson, P.G.1
  • 11
    • 0029903432 scopus 로고    scopus 로고
    • Bronchoscopy as a research tool for the study of asthma pathogenesis and effects of antiasthma drugs
    • (discussion S64-6)
    • R. Djukanovic Bronchoscopy as a research tool for the study of asthma pathogenesis and effects of antiasthma drugs J. Allergy Clin. Immunol. 98 5 Pt 2 1996 S41 S45 (discussion S64-6)
    • (1996) J. Allergy Clin. Immunol. , vol.98 , Issue.5 PART 2
    • Djukanovic, R.1
  • 12
    • 78649335507 scopus 로고    scopus 로고
    • Biomarkers in asthma and allergic rhinitis
    • Z. Diamant Biomarkers in asthma and allergic rhinitis Pulm. Pharmacol. Ther. 23 6 2010 468 481
    • (2010) Pulm. Pharmacol. Ther. , vol.23 , Issue.6 , pp. 468-481
    • Diamant, Z.1
  • 13
    • 84863229915 scopus 로고    scopus 로고
    • Asthma outcomes: Biomarkers
    • S.J. Szefler Asthma outcomes: biomarkers J. Allergy Clin. Immunol. 129 3 Suppl. 2012 S9 S23
    • (2012) J. Allergy Clin. Immunol. , vol.129 , Issue.3 SUPPL.
    • Szefler, S.J.1
  • 14
    • 31144451043 scopus 로고    scopus 로고
    • Biomarkers predicting response to corticosteroid therapy in asthma
    • C.E. Brightling, R.H. Green, and I.D. Pavord Biomarkers predicting response to corticosteroid therapy in asthma Treat. Respir. Med. 4 5 2005 309 316
    • (2005) Treat. Respir. Med. , vol.4 , Issue.5 , pp. 309-316
    • Brightling, C.E.1    Green, R.H.2    Pavord, I.D.3
  • 15
    • 80053084755 scopus 로고    scopus 로고
    • Lebrikizumab treatment in adults with asthma
    • J. Corren Lebrikizumab treatment in adults with asthma N. Engl. J. Med. 365 12 2011 1088 1098
    • (2011) N. Engl. J. Med. , vol.365 , Issue.12 , pp. 1088-1098
    • Corren, J.1
  • 16
    • 0035891664 scopus 로고    scopus 로고
    • Remodeling in asthma and chronic obstructive lung disease
    • P.K. Jeffery Remodeling in asthma and chronic obstructive lung disease Am. J. Respir. Crit. Care Med. 164 10 Pt. 2 2001 S28 S38
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , Issue.10 PART 2
    • Jeffery, P.K.1
  • 17
    • 0033060552 scopus 로고    scopus 로고
    • How much asthma is really attributable to atopy?
    • N. Pearce, J. Pekkanen, and R. Beasley How much asthma is really attributable to atopy? Thorax 54 3 1999 268 272
    • (1999) Thorax , vol.54 , Issue.3 , pp. 268-272
    • Pearce, N.1    Pekkanen, J.2    Beasley, R.3
  • 18
    • 79959369140 scopus 로고    scopus 로고
    • The sentinel role of the airway epithelium in asthma pathogenesis
    • S.T. Holgate The sentinel role of the airway epithelium in asthma pathogenesis Immunol. Rev. 242 1 2011 205 219
    • (2011) Immunol. Rev. , vol.242 , Issue.1 , pp. 205-219
    • Holgate, S.T.1
  • 19
    • 77957113600 scopus 로고    scopus 로고
    • A large-scale, consortium-based genomewide association study of asthma
    • M.F. Moffatt A large-scale, consortium-based genomewide association study of asthma N. Engl. J. Med. 363 13 2010 1211 1221
    • (2010) N. Engl. J. Med. , vol.363 , Issue.13 , pp. 1211-1221
    • Moffatt, M.F.1
  • 20
    • 0037173639 scopus 로고    scopus 로고
    • Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
    • P. Van Eerdewegh Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness Nature 418 6896 2002 426 430
    • (2002) Nature , vol.418 , Issue.6896 , pp. 426-430
    • Van Eerdewegh, P.1
  • 21
    • 79953279646 scopus 로고    scopus 로고
    • Genome-wide association studies for discovery of genes involved in asthma
    • L. Akhabir, and A.J. Sandford Genome-wide association studies for discovery of genes involved in asthma Respirology 16 3 2011 396 406
    • (2011) Respirology , vol.16 , Issue.3 , pp. 396-406
    • Akhabir, L.1    Sandford, A.J.2
  • 22
    • 83155173902 scopus 로고    scopus 로고
    • Genetic and genomic approaches to asthma: New insights for the origins
    • Y. Zhang, M.F. Moffatt, and W.O. Cookson Genetic and genomic approaches to asthma: new insights for the origins Curr. Opin. Pulm. Med. 18 1 2012 6 13
    • (2012) Curr. Opin. Pulm. Med. , vol.18 , Issue.1 , pp. 6-13
    • Zhang, Y.1    Moffatt, M.F.2    Cookson, W.O.3
  • 23
    • 67649205370 scopus 로고    scopus 로고
    • Breakdown in epithelial barrier function in patients with asthma: Identification of novel therapeutic approaches
    • (quiz 35-6)
    • E.J. Swindle, J.E. Collins, and D.E. Davies Breakdown in epithelial barrier function in patients with asthma: identification of novel therapeutic approaches J. Allergy Clin. Immunol. 124 1 2009 23 34 (quiz 35-6)
    • (2009) J. Allergy Clin. Immunol. , vol.124 , Issue.1 , pp. 23-34
    • Swindle, E.J.1    Collins, J.E.2    Davies, D.E.3
  • 24
    • 80052219553 scopus 로고    scopus 로고
    • Defective epithelial barrier function in asthma
    • (e1-12)
    • C. Xiao Defective epithelial barrier function in asthma J. Allergy Clin. Immunol. 128 3 2011 549 556 (e1-12)
    • (2011) J. Allergy Clin. Immunol. , vol.128 , Issue.3 , pp. 549-556
    • Xiao, C.1
  • 26
    • 70249121493 scopus 로고    scopus 로고
    • Rethinking the pathogenesis of asthma
    • S.T. Holgate, and D.E. Davies Rethinking the pathogenesis of asthma Immunity 31 3 2009 362 367
    • (2009) Immunity , vol.31 , Issue.3 , pp. 362-367
    • Holgate, S.T.1    Davies, D.E.2
  • 27
    • 84555195154 scopus 로고    scopus 로고
    • A Drosophila asthma model-what the fly tells us about inflammatory diseases of the lung
    • T. Roeder A Drosophila asthma model-what the fly tells us about inflammatory diseases of the lung Adv. Exp. Med. Biol. 710 2012 37 47
    • (2012) Adv. Exp. Med. Biol. , vol.710 , pp. 37-47
    • Roeder, T.1
  • 28
    • 50849090306 scopus 로고    scopus 로고
    • The non-human primate as a model for studying COPD and asthma
    • C.G. Plopper, and D.M. Hyde The non-human primate as a model for studying COPD and asthma Pulm. Pharmacol. Ther. 21 5 2008 755 766
    • (2008) Pulm. Pharmacol. Ther. , vol.21 , Issue.5 , pp. 755-766
    • Plopper, C.G.1    Hyde, D.M.2
  • 29
    • 34250763237 scopus 로고    scopus 로고
    • Animal models of asthma
    • G.R. Zosky, and P.D. Sly Animal models of asthma Clin. Exp. Allergy 37 7 2007 973 988
    • (2007) Clin. Exp. Allergy , vol.37 , Issue.7 , pp. 973-988
    • Zosky, G.R.1    Sly, P.D.2
  • 30
    • 47749090524 scopus 로고    scopus 로고
    • Use of alternative animals as asthma models
    • N. Kirschvink, and P. Reinhold Use of alternative animals as asthma models Curr. Drug Targets 9 6 2008 470 484
    • (2008) Curr. Drug Targets , vol.9 , Issue.6 , pp. 470-484
    • Kirschvink, N.1    Reinhold, P.2
  • 31
    • 47749152971 scopus 로고    scopus 로고
    • Experimental bronchial asthma-The strength of the species rat
    • T. Tschernig Experimental bronchial asthma-the strength of the species rat Curr. Drug Targets 9 6 2008 466 469
    • (2008) Curr. Drug Targets , vol.9 , Issue.6 , pp. 466-469
    • Tschernig, T.1
  • 32
    • 0034493299 scopus 로고    scopus 로고
    • Animal models of bronchial asthma
    • I. Szelenyi Animal models of bronchial asthma Inflamm. Res. 49 12 2000 639 654
    • (2000) Inflamm. Res. , vol.49 , Issue.12 , pp. 639-654
    • Szelenyi, I.1
  • 33
    • 0026874218 scopus 로고
    • Chronic lower airway disease in the dog and cat
    • P. Padrid Chronic lower airway disease in the dog and cat Probl. Vet. Med. 4 2 1992 320 344
    • (1992) Probl. Vet. Med. , vol.4 , Issue.2 , pp. 320-344
    • Padrid, P.1
  • 34
    • 33746576456 scopus 로고    scopus 로고
    • Heaves, an asthma-like equine disease, involves airway smooth muscle remodeling
    • B. Herszberg Heaves, an asthma-like equine disease, involves airway smooth muscle remodeling J. Allergy Clin. Immunol. 118 2 2006 382 388
    • (2006) J. Allergy Clin. Immunol. , vol.118 , Issue.2 , pp. 382-388
    • Herszberg, B.1
  • 35
    • 80053300921 scopus 로고    scopus 로고
    • Heaves, an asthma-like disease of horses
    • M. Leclere, A. Lavoie-Lamoureux, and J.P. Lavoie Heaves, an asthma-like disease of horses Respirology 16 7 2011 1027 1046
    • (2011) Respirology , vol.16 , Issue.7 , pp. 1027-1046
    • Leclere, M.1    Lavoie-Lamoureux, A.2    Lavoie, J.P.3
  • 36
    • 64049085035 scopus 로고    scopus 로고
    • Mechanism of action of clinically approved adjuvants
    • B.N. Lambrecht Mechanism of action of clinically approved adjuvants Curr. Opin. Immunol. 21 1 2009 23 29
    • (2009) Curr. Opin. Immunol. , vol.21 , Issue.1 , pp. 23-29
    • Lambrecht, B.N.1
  • 37
    • 33750803442 scopus 로고    scopus 로고
    • Pertussis toxin is superior to TLR ligands in enhancing pathogenic autoimmunity, targeted at a neo-self antigen, by triggering robust expansion of Th1 cells and their cytokine production
    • C. Fujimoto Pertussis toxin is superior to TLR ligands in enhancing pathogenic autoimmunity, targeted at a neo-self antigen, by triggering robust expansion of Th1 cells and their cytokine production J. Immunol. 177 10 2006 6896 6903
    • (2006) J. Immunol. , vol.177 , Issue.10 , pp. 6896-6903
    • Fujimoto, C.1
  • 38
    • 0142012149 scopus 로고    scopus 로고
    • Mouse model of airway remodeling: Strain differences
    • K. Shinagawa, and M. Kojima Mouse model of airway remodeling: strain differences Am. J. Respir. Crit. Care Med. 168 8 2003 959 967
    • (2003) Am. J. Respir. Crit. Care Med. , vol.168 , Issue.8 , pp. 959-967
    • Shinagawa, K.1    Kojima, M.2
  • 39
    • 59849125377 scopus 로고    scopus 로고
    • Comparison of acute inflammatory and chronic structural asthma-like responses between C57BL/6 and BALB/c mice
    • C.L. Van Hove Comparison of acute inflammatory and chronic structural asthma-like responses between C57BL/6 and BALB/c mice Int. Arch. Allergy Immunol. 149 3 2009 195 207
    • (2009) Int. Arch. Allergy Immunol. , vol.149 , Issue.3 , pp. 195-207
    • Van Hove, C.L.1
  • 40
    • 33748546919 scopus 로고    scopus 로고
    • Current animal models of bronchial asthma
    • I. Kurucz, and I. Szelenyi Current animal models of bronchial asthma Curr. Pharm. Des. 12 25 2006 3175 3194
    • (2006) Curr. Pharm. Des. , vol.12 , Issue.25 , pp. 3175-3194
    • Kurucz, I.1    Szelenyi, I.2
  • 41
    • 77949897036 scopus 로고    scopus 로고
    • Importance of cytokines in murine allergic airway disease and human asthma
    • F.D. Finkelman Importance of cytokines in murine allergic airway disease and human asthma J. Immunol. 184 4 2010 1663 1674
    • (2010) J. Immunol. , vol.184 , Issue.4 , pp. 1663-1674
    • Finkelman, F.D.1
  • 42
    • 33845870421 scopus 로고    scopus 로고
    • Promise and pitfalls in animal-based asthma research: Building a better mousetrap
    • D.B. Corry, and C.G. Irvin Promise and pitfalls in animal-based asthma research: building a better mousetrap Immunol. Res. 35 3 2006 279 294
    • (2006) Immunol. Res. , vol.35 , Issue.3 , pp. 279-294
    • Corry, D.B.1    Irvin, C.G.2
  • 43
    • 78650028281 scopus 로고    scopus 로고
    • Transgenic modelling of cytokine polarization in the lung
    • C.S. Dela Cruz Transgenic modelling of cytokine polarization in the lung Immunology 132 1 2011 9 17
    • (2011) Immunology , vol.132 , Issue.1 , pp. 9-17
    • Dela Cruz, C.S.1
  • 44
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • H. Hammad House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells Nat. Med. 15 4 2009 410 416
    • (2009) Nat. Med. , vol.15 , Issue.4 , pp. 410-416
    • Hammad, H.1
  • 45
    • 80051548418 scopus 로고    scopus 로고
    • Asthma translational medicine: Report card
    • K. Mullane Asthma translational medicine: report card Biochem. Pharmacol. 82 6 2011 567 585
    • (2011) Biochem. Pharmacol. , vol.82 , Issue.6 , pp. 567-585
    • Mullane, K.1
  • 46
    • 5644221318 scopus 로고    scopus 로고
    • Insights into the pathogenesis of asthma utilizing murine models
    • C. Taube, A. Dakhama, and E.W. Gelfand Insights into the pathogenesis of asthma utilizing murine models Int. Arch. Allergy Immunol. 135 2 2004 173 186
    • (2004) Int. Arch. Allergy Immunol. , vol.135 , Issue.2 , pp. 173-186
    • Taube, C.1    Dakhama, A.2    Gelfand, E.W.3
  • 47
    • 36049007283 scopus 로고    scopus 로고
    • Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers
    • S. Saglani Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers Am. J. Respir. Crit. Care Med. 176 9 2007 858 864
    • (2007) Am. J. Respir. Crit. Care Med. , vol.176 , Issue.9 , pp. 858-864
    • Saglani, S.1
  • 48
    • 0031732187 scopus 로고    scopus 로고
    • Afferent receptors in the airways and cough
    • J.G. Widdicombe Afferent receptors in the airways and cough Respir. Physiol. 114 1 1998 5 15
    • (1998) Respir. Physiol. , vol.114 , Issue.1 , pp. 5-15
    • Widdicombe, J.G.1
  • 49
    • 0035126626 scopus 로고    scopus 로고
    • Neural regulation of airway smooth muscle tone
    • B.J. Canning, and A. Fischer Neural regulation of airway smooth muscle tone Respir. Physiol. 125 1-2 2001 113 127
    • (2001) Respir. Physiol. , vol.125 , Issue.12 , pp. 113-127
    • Canning, B.J.1    Fischer, A.2
  • 50
    • 0028817013 scopus 로고
    • Airway hyperresponsiveness in asthma: A problem of limited smooth muscle relaxation with inspiration
    • G. Skloot, S. Permutt, and A. Togias Airway hyperresponsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration J. Clin. Invest. 96 5 1995 2393 2403
    • (1995) J. Clin. Invest. , vol.96 , Issue.5 , pp. 2393-2403
    • Skloot, G.1    Permutt, S.2    Togias, A.3
  • 51
    • 80051670719 scopus 로고    scopus 로고
    • Animal models of asthma: Value, limitations and opportunities for alternative approaches
    • A.M. Holmes, R. Solari, and S.T. Holgate Animal models of asthma: value, limitations and opportunities for alternative approaches Drug Discov. Today 16 15-16 2011 659 670
    • (2011) Drug Discov. Today , vol.16 , Issue.1516 , pp. 659-670
    • Holmes, A.M.1    Solari, R.2    Holgate, S.T.3
  • 52
    • 0029986125 scopus 로고    scopus 로고
    • Safety aspects of local endobronchial allergen challenge in asthmatic patients
    • N. Krug Safety aspects of local endobronchial allergen challenge in asthmatic patients Am. J. Respir. Crit. Care Med. 153 4 Pt 1 1996 1391 1397
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , Issue.4 PART 1 , pp. 1391-1397
    • Krug, N.1
  • 53
    • 81255154034 scopus 로고    scopus 로고
    • Artificial airways for the study of respiratory disease
    • E.J. Swindle, and D.E. Davies Artificial airways for the study of respiratory disease Expert Rev. Respir. Med. 5 6 2011 757 765
    • (2011) Expert Rev. Respir. Med. , vol.5 , Issue.6 , pp. 757-765
    • Swindle, E.J.1    Davies, D.E.2
  • 54
    • 0037975657 scopus 로고    scopus 로고
    • The early allergic response in small airways of human precision-cut lung slices
    • A. Wohlsen The early allergic response in small airways of human precision-cut lung slices Eur. Respir. J. 21 6 2003 1024 1032
    • (2003) Eur. Respir. J. , vol.21 , Issue.6 , pp. 1024-1032
    • Wohlsen, A.1
  • 55
    • 77956870517 scopus 로고    scopus 로고
    • Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices
    • S. Switalla Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices Toxicol. Appl. Pharmacol. 2010
    • (2010) Toxicol. Appl. Pharmacol.
    • Switalla, S.1
  • 56
    • 48449094129 scopus 로고    scopus 로고
    • Ex vivo testing of immune responses in precision-cut lung slices
    • M. Henjakovic Ex vivo testing of immune responses in precision-cut lung slices Toxicol. Appl. Pharmacol. 231 1 2008 68 76
    • (2008) Toxicol. Appl. Pharmacol. , vol.231 , Issue.1 , pp. 68-76
    • Henjakovic, M.1
  • 57
    • 37348999950 scopus 로고    scopus 로고
    • Pharmacological characterization of indacaterol, a novel once daily inhaled 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices
    • R.G. Sturton Pharmacological characterization of indacaterol, a novel once daily inhaled 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices J. Pharmacol. Exp. Ther. 324 1 2008 270 275
    • (2008) J. Pharmacol. Exp. Ther. , vol.324 , Issue.1 , pp. 270-275
    • Sturton, R.G.1
  • 58
    • 0033485406 scopus 로고    scopus 로고
    • Essential role for both CD80 and CD86 costimulation, but not CD40 interactions, in allergen-induced Th2 cytokine production from asthmatic bronchial tissue: Role for alphabeta, but not gammadelta, T cells
    • Z.H. Jaffar Essential role for both CD80 and CD86 costimulation, but not CD40 interactions, in allergen-induced Th2 cytokine production from asthmatic bronchial tissue: role for alphabeta, but not gammadelta, T cells J. Immunol. 163 11 1999 6283 6291
    • (1999) J. Immunol. , vol.163 , Issue.11 , pp. 6283-6291
    • Jaffar, Z.H.1
  • 59
    • 0033964866 scopus 로고    scopus 로고
    • Role of B7-CD28/CTLA-4 costimulation and NF-kappa B in allergen-induced T cell chemotaxis by IL-16 and RANTES
    • R. Hidi Role of B7-CD28/CTLA-4 costimulation and NF-kappa B in allergen-induced T cell chemotaxis by IL-16 and RANTES J. Immunol. 164 1 2000 412 418
    • (2000) J. Immunol. , vol.164 , Issue.1 , pp. 412-418
    • Hidi, R.1
  • 60
    • 0035217153 scopus 로고    scopus 로고
    • The role of CD28-B7 costimulation in allergen-induced cytokine release by bronchial mucosa from patients with moderately severe asthma
    • J.L. Lordan The role of CD28-B7 costimulation in allergen-induced cytokine release by bronchial mucosa from patients with moderately severe asthma J. Allergy Clin. Immunol. 108 6 2001 976 981
    • (2001) J. Allergy Clin. Immunol. , vol.108 , Issue.6 , pp. 976-981
    • Lordan, J.L.1
  • 61
    • 77952783111 scopus 로고    scopus 로고
    • Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients
    • P. Vijayanand Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients J. Immunol. 184 8 2010 4568 4574
    • (2010) J. Immunol. , vol.184 , Issue.8 , pp. 4568-4574
    • Vijayanand, P.1
  • 62
    • 79960414056 scopus 로고    scopus 로고
    • Role of interleukin-1 and MyD88-dependent signaling in rhinovirus infection
    • C.A. Stokes Role of interleukin-1 and MyD88-dependent signaling in rhinovirus infection J. Virol. 85 15 2011 7912 7921
    • (2011) J. Virol. , vol.85 , Issue.15 , pp. 7912-7921
    • Stokes, C.A.1
  • 63
    • 84860320293 scopus 로고    scopus 로고
    • Rhinovirus-induced MMP-9 expression is dependent on Fra-1, which is modulated by formoterol and dexamethasone
    • C.E. Tacon Rhinovirus-induced MMP-9 expression is dependent on Fra-1, which is modulated by formoterol and dexamethasone J. Immunol. 188 9 2012 4621 4630
    • (2012) J. Immunol. , vol.188 , Issue.9 , pp. 4621-4630
    • Tacon, C.E.1
  • 64
    • 79960015037 scopus 로고    scopus 로고
    • Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides
    • R. Vinhas Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides Allergy 66 8 2011 1088 1098
    • (2011) Allergy , vol.66 , Issue.8 , pp. 1088-1098
    • Vinhas, R.1
  • 65
    • 0035086672 scopus 로고    scopus 로고
    • The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus
    • H. Wan The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus Clin. Exp. Allergy 31 2 2001 279 294
    • (2001) Clin. Exp. Allergy , vol.31 , Issue.2 , pp. 279-294
    • Wan, H.1
  • 66
    • 84859839025 scopus 로고    scopus 로고
    • Functional effects of nanoparticle exposure on Calu-3 airway epithelial cells
    • A. Banga Functional effects of nanoparticle exposure on Calu-3 airway epithelial cells Cell Physiol. Biochem. 29 1-2 2012 197 212
    • (2012) Cell Physiol. Biochem. , vol.29 , Issue.12 , pp. 197-212
    • Banga, A.1
  • 67
    • 83655190177 scopus 로고    scopus 로고
    • Cigarette smoke impairs airway epithelial barrier function and cell-cell contact recovery
    • I.H. Heijink Cigarette smoke impairs airway epithelial barrier function and cell-cell contact recovery Eur. Respir. J. 39 2 2012 419 428
    • (2012) Eur. Respir. J. , vol.39 , Issue.2 , pp. 419-428
    • Heijink, I.H.1
  • 68
    • 60849116458 scopus 로고    scopus 로고
    • Cigarette smoke facilitates allergen penetration across respiratory epithelium
    • K. Gangl Cigarette smoke facilitates allergen penetration across respiratory epithelium Allergy 64 3 2009 398 405
    • (2009) Allergy , vol.64 , Issue.3 , pp. 398-405
    • Gangl, K.1
  • 69
    • 79955750451 scopus 로고    scopus 로고
    • Evaluation of the Calu-3 cell line as a model of in vitro respiratory syncytial virus infection
    • J.L. Harcourt Evaluation of the Calu-3 cell line as a model of in vitro respiratory syncytial virus infection J. Virol. Methods 174 1-2 2011 144 149
    • (2011) J. Virol. Methods , vol.174 , Issue.12 , pp. 144-149
    • Harcourt, J.L.1
  • 70
    • 82555205301 scopus 로고    scopus 로고
    • Polyinosinic:polycytidylic acid induces protein kinase D-dependent disassembly of apical junctions and barrier dysfunction in airway epithelial cells
    • (e11)
    • F. Rezaee Polyinosinic:polycytidylic acid induces protein kinase D-dependent disassembly of apical junctions and barrier dysfunction in airway epithelial cells J. Allergy Clin. Immunol. 128 6 2011 1216 1224 (e11)
    • (2011) J. Allergy Clin. Immunol. , vol.128 , Issue.6 , pp. 1216-1224
    • Rezaee, F.1
  • 71
    • 0035984581 scopus 로고    scopus 로고
    • Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis
    • F. Bucchieri Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis Am. J. Respir. Cell Mol. Biol. 27 2 2002 179 185
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.27 , Issue.2 , pp. 179-185
    • Bucchieri, F.1
  • 72
    • 0032937261 scopus 로고    scopus 로고
    • Differences between cytokine release from bronchial epithelial cells of asthmatic patients and non-asthmatic subjects: Effect of exposure to diesel exhaust particles
    • J.L. Devalia Differences between cytokine release from bronchial epithelial cells of asthmatic patients and non-asthmatic subjects: effect of exposure to diesel exhaust particles Int. Arch. Allergy Immunol. 118 2-4 1999 437 439
    • (1999) Int. Arch. Allergy Immunol. , vol.118 , Issue.24 , pp. 437-439
    • Devalia, J.L.1
  • 73
    • 33645566960 scopus 로고    scopus 로고
    • Enhanced upregulation of smooth muscle related transcripts by TGF beta2 in asthmatic (myo) fibroblasts
    • J. Wicks Enhanced upregulation of smooth muscle related transcripts by TGF beta2 in asthmatic (myo) fibroblasts Thorax 61 4 2006 313 319
    • (2006) Thorax , vol.61 , Issue.4 , pp. 313-319
    • Wicks, J.1
  • 74
    • 0035423346 scopus 로고    scopus 로고
    • Airway smooth muscle cell proliferation is increased in asthma
    • P.R. Johnson Airway smooth muscle cell proliferation is increased in asthma Am. J. Respir. Crit. Care Med. 164 3 2001 474 477
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , Issue.3 , pp. 474-477
    • Johnson, P.R.1
  • 75
    • 0031794739 scopus 로고    scopus 로고
    • Alveolar macrophage interleukin (IL)-10 and IL-12 production in atopic asthma
    • A. Magnan Alveolar macrophage interleukin (IL)-10 and IL-12 production in atopic asthma Allergy 53 11 1998 1092 1095
    • (1998) Allergy , vol.53 , Issue.11 , pp. 1092-1095
    • Magnan, A.1
  • 76
    • 33644627581 scopus 로고    scopus 로고
    • Functional and phenotypical comparison of myofibroblasts derived from biopsies and bronchoalveolar lavage in mild asthma and scleroderma
    • K. Larsen Functional and phenotypical comparison of myofibroblasts derived from biopsies and bronchoalveolar lavage in mild asthma and scleroderma Respir. Res. 7 2006 11
    • (2006) Respir. Res. , vol.7 , pp. 11
    • Larsen, K.1
  • 77
    • 17144403499 scopus 로고    scopus 로고
    • Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
    • P.A. Wark Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus J. Exp. Med. 201 6 2005 937 947
    • (2005) J. Exp. Med. , vol.201 , Issue.6 , pp. 937-947
    • Wark, P.A.1
  • 78
    • 77955300029 scopus 로고    scopus 로고
    • Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma
    • L. Uller Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma Thorax 65 7 2010 626 632
    • (2010) Thorax , vol.65 , Issue.7 , pp. 626-632
    • Uller, L.1
  • 79
    • 79955634439 scopus 로고    scopus 로고
    • Exogenous IFN-beta has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus
    • (e9)
    • J.A. Cakebread Exogenous IFN-beta has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus J. Allergy Clin. Immunol. 127 5 2011 1148 1154 (e9)
    • (2011) J. Allergy Clin. Immunol. , vol.127 , Issue.5 , pp. 1148-1154
    • Cakebread, J.A.1
  • 80
    • 78650653743 scopus 로고    scopus 로고
    • The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia
    • A.A. Pezzulo The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia Am. J. Physiol. Lung Cell Mol. Physiol. 300 1 2011 L25 L31
    • (2011) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.300 , Issue.1
    • Pezzulo, A.A.1
  • 81
    • 82155175243 scopus 로고    scopus 로고
    • IL-13-induced MUC5AC production and goblet cell differentiation is steroid resistant in human airway cells
    • S. Kanoh, T. Tanabe, and B.K. Rubin IL-13-induced MUC5AC production and goblet cell differentiation is steroid resistant in human airway cells Clin. Exp. Allergy 41 12 2011 1747 1756
    • (2011) Clin. Exp. Allergy , vol.41 , Issue.12 , pp. 1747-1756
    • Kanoh, S.1    Tanabe, T.2    Rubin, B.K.3
  • 82
    • 79951667883 scopus 로고    scopus 로고
    • Effects of IL-13 on mucociliary differentiation of pediatric asthmatic bronchial epithelial cells
    • S. Thavagnanam Effects of IL-13 on mucociliary differentiation of pediatric asthmatic bronchial epithelial cells Pediatr. Res. 69 2 2011 95 100
    • (2011) Pediatr. Res. , vol.69 , Issue.2 , pp. 95-100
    • Thavagnanam, S.1
  • 83
    • 79955368069 scopus 로고    scopus 로고
    • IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides
    • S. Zuyderduyn IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides Respir. Res. 12 2011 59
    • (2011) Respir. Res. , vol.12 , pp. 59
    • Zuyderduyn, S.1
  • 84
    • 0036037574 scopus 로고    scopus 로고
    • Effect of ozone and nitrogen dioxide on the permeability of bronchial epithelial cell cultures of non-asthmatic and asthmatic subjects
    • H. Bayram Effect of ozone and nitrogen dioxide on the permeability of bronchial epithelial cell cultures of non-asthmatic and asthmatic subjects Clin. Exp. Allergy 32 9 2002 1285 1292
    • (2002) Clin. Exp. Allergy , vol.32 , Issue.9 , pp. 1285-1292
    • Bayram, H.1
  • 85
    • 80052232772 scopus 로고    scopus 로고
    • Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution
    • T.L. Hackett Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution Am. J. Respir. Cell Mol. Biol. 45 5 2011 1090 1100
    • (2011) Am. J. Respir. Cell Mol. Biol. , vol.45 , Issue.5 , pp. 1090-1100
    • Hackett, T.L.1
  • 86
    • 0027080197 scopus 로고
    • The effects of salmeterol and salbutamol on ciliary beat frequency of cultured human bronchial epithelial cells, in vitro
    • J.L. Devalia The effects of salmeterol and salbutamol on ciliary beat frequency of cultured human bronchial epithelial cells, in vitro Pulm. Pharmacol. 5 4 1992 257 263
    • (1992) Pulm. Pharmacol. , vol.5 , Issue.4 , pp. 257-263
    • Devalia, J.L.1
  • 87
    • 0031785140 scopus 로고    scopus 로고
    • Comparison of ciliary activity and inflammatory mediator release from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic asthmatic patients and the effect of diesel exhaust particles in vitro
    • H. Bayram Comparison of ciliary activity and inflammatory mediator release from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic asthmatic patients and the effect of diesel exhaust particles in vitro J. Allergy Clin. Immunol. 102 5 1998 771 782
    • (1998) J. Allergy Clin. Immunol. , vol.102 , Issue.5 , pp. 771-782
    • Bayram, H.1
  • 88
    • 0033919590 scopus 로고    scopus 로고
    • Secretory differentiation of serially passaged normal human nasal epithelial cells by retinoic acid: Expression of mucin and lysozyme
    • J.H. Yoon Secretory differentiation of serially passaged normal human nasal epithelial cells by retinoic acid: expression of mucin and lysozyme Ann. Otol. Rhinol. Laryngol. 109 6 2000 594 601
    • (2000) Ann. Otol. Rhinol. Laryngol. , vol.109 , Issue.6 , pp. 594-601
    • Yoon, J.H.1
  • 89
    • 10844284696 scopus 로고    scopus 로고
    • Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins
    • R.D. Ramirez Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins Cancer Res. 64 24 2004 9027 9034
    • (2004) Cancer Res. , vol.64 , Issue.24 , pp. 9027-9034
    • Ramirez, R.D.1
  • 90
    • 33644512890 scopus 로고    scopus 로고
    • A three-dimensional model of differentiation of immortalized human bronchial epithelial cells
    • M.B. Vaughan A three-dimensional model of differentiation of immortalized human bronchial epithelial cells Differentiation 74 4 2006 141 148
    • (2006) Differentiation , vol.74 , Issue.4 , pp. 141-148
    • Vaughan, M.B.1
  • 91
    • 55049093300 scopus 로고    scopus 로고
    • Characterization of side population cells from human airway epithelium
    • T.L. Hackett Characterization of side population cells from human airway epithelium Stem Cells 26 10 2008 2576 2585
    • (2008) Stem Cells , vol.26 , Issue.10 , pp. 2576-2585
    • Hackett, T.L.1
  • 92
    • 77956538031 scopus 로고    scopus 로고
    • Airway basal stem cells: A perspective on their roles in epithelial homeostasis and remodeling
    • J.R. Rock, S.H. Randell, and B.L. Hogan Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling Dis. Model. Mech. 3 9-10 2010 545 556
    • (2010) Dis. Model. Mech. , vol.3 , Issue.910 , pp. 545-556
    • Rock, J.R.1    Randell, S.H.2    Hogan, B.L.3
  • 93
    • 40549117517 scopus 로고    scopus 로고
    • Bronchial epithelial spheroids: An alternative culture model to investigate epithelium inflammation-mediated COPD
    • G. Deslee Bronchial epithelial spheroids: an alternative culture model to investigate epithelium inflammation-mediated COPD Respir. Res. 8 2007 86
    • (2007) Respir. Res. , vol.8 , pp. 86
    • Deslee, G.1
  • 94
    • 79960861882 scopus 로고    scopus 로고
    • Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix
    • X. Wu Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix Am. J. Respir. Cell Mol. Biol. 44 6 2011 914 921
    • (2011) Am. J. Respir. Cell Mol. Biol. , vol.44 , Issue.6 , pp. 914-921
    • Wu, X.1
  • 95
    • 34248223108 scopus 로고    scopus 로고
    • Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis
    • W. Yu Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis Mol. Biol. Cell 18 5 2007 1693 1700
    • (2007) Mol. Biol. Cell , vol.18 , Issue.5 , pp. 1693-1700
    • Yu, W.1
  • 96
    • 78649325909 scopus 로고    scopus 로고
    • Airway branching morphogenesis in three dimensional culture
    • S.R. Franzdottir Airway branching morphogenesis in three dimensional culture Respir. Res. 11 2010 162
    • (2010) Respir. Res. , vol.11 , pp. 162
    • Franzdottir, S.R.1
  • 97
    • 16544380146 scopus 로고    scopus 로고
    • The use of 3-D cultures for high-throughput screening: The multicellular spheroid model
    • L.A. Kunz-Schughart The use of 3-D cultures for high-throughput screening: the multicellular spheroid model J. Biomol. Screen. 9 4 2004 273 285
    • (2004) J. Biomol. Screen. , vol.9 , Issue.4 , pp. 273-285
    • Kunz-Schughart, L.A.1
  • 98
    • 77953914467 scopus 로고    scopus 로고
    • Acute cytotoxicity and apoptotic effects after l-Pam exposure in different cocultures of the proximal and distal respiratory system
    • C. Pohl Acute cytotoxicity and apoptotic effects after l-Pam exposure in different cocultures of the proximal and distal respiratory system J. Biotechnol. 148 1 2010 31 37
    • (2010) J. Biotechnol. , vol.148 , Issue.1 , pp. 31-37
    • Pohl, C.1
  • 99
    • 33845433256 scopus 로고    scopus 로고
    • Epithelial-derived TGF-beta2 modulates basal and wound-healing subepithelial matrix homeostasis
    • p. L1277-85
    • H.G. Thompson Epithelial-derived TGF-beta2 modulates basal and wound-healing subepithelial matrix homeostasis Am. J. Physiol. Lung Cell Mol. Physiol. 291 6 2006 p. L1277-85
    • (2006) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.291 , Issue.6
    • Thompson, H.G.1
  • 100
    • 69449101937 scopus 로고    scopus 로고
    • Airway epithelium stimulates smooth muscle proliferation
    • N.K. Malavia Airway epithelium stimulates smooth muscle proliferation Am. J. Respir. Cell Mol. Biol. 41 3 2009 297 304
    • (2009) Am. J. Respir. Cell Mol. Biol. , vol.41 , Issue.3 , pp. 297-304
    • Malavia, N.K.1
  • 101
    • 40749093735 scopus 로고    scopus 로고
    • Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model
    • A.A. Tomei, M.M. Choe, and M.A. Swartz Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model Am. J. Physiol. Lung Cell Mol. Physiol. 294 1 2008 L79 L86
    • (2008) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.294 , Issue.1
    • Tomei, A.A.1    Choe, M.M.2    Swartz, M.A.3
  • 103
    • 76749166268 scopus 로고    scopus 로고
    • Interactions between endothelial cells and epithelial cells in a combined cell model of airway mucosa: Effects on tight junction permeability
    • F. Chowdhury Interactions between endothelial cells and epithelial cells in a combined cell model of airway mucosa: effects on tight junction permeability Exp. Lung Res. 36 1 2010 1 11
    • (2010) Exp. Lung Res. , vol.36 , Issue.1 , pp. 1-11
    • Chowdhury, F.1
  • 104
    • 79952310806 scopus 로고    scopus 로고
    • An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier
    • A.D. Lehmann An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier Eur. J. Pharm. Biopharm. 77 3 2011 398 406
    • (2011) Eur. J. Pharm. Biopharm. , vol.77 , Issue.3 , pp. 398-406
    • Lehmann, A.D.1
  • 105
    • 16444371242 scopus 로고    scopus 로고
    • A three-dimensional cellular model of the human respiratory tract to study the interaction with particles
    • B.M. Rothen-Rutishauser, S.G. Kiama, and P. Gehr A three-dimensional cellular model of the human respiratory tract to study the interaction with particles Am. J. Respir. Cell Mol. Biol. 32 4 2005 281 289
    • (2005) Am. J. Respir. Cell Mol. Biol. , vol.32 , Issue.4 , pp. 281-289
    • Rothen-Rutishauser, B.M.1    Kiama, S.G.2    Gehr, P.3
  • 106
    • 78649503402 scopus 로고    scopus 로고
    • Macrophages and dendritic cells express tight junction proteins and exchange particles in an in vitro model of the human airway wall
    • F. Blank Macrophages and dendritic cells express tight junction proteins and exchange particles in an in vitro model of the human airway wall Immunobiology 216 1-2 2011 86 95
    • (2011) Immunobiology , vol.216 , Issue.12 , pp. 86-95
    • Blank, F.1
  • 107
    • 84855332758 scopus 로고    scopus 로고
    • Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa
    • L226-37
    • A.T. Nguyen Hoang Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa Am. J. Physiol. Lung Cell Mol. Physiol. 302 2 2012 L226-37
    • (2012) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.302 , Issue.2
    • Nguyen Hoang, A.T.1
  • 108
    • 77953101663 scopus 로고    scopus 로고
    • On-chip epithelial barrier function assays using electrical impedance spectroscopy
    • T. Sun On-chip epithelial barrier function assays using electrical impedance spectroscopy Lab. Chip 10 12 2010 1611 1617
    • (2010) Lab. Chip , vol.10 , Issue.12 , pp. 1611-1617
    • Sun, T.1
  • 109
    • 77954038080 scopus 로고    scopus 로고
    • Reconstituting organ-level lung functions on a chip
    • D. Huh Reconstituting organ-level lung functions on a chip Science 328 5986 2010 1662 1668
    • (2010) Science , vol.328 , Issue.5986 , pp. 1662-1668
    • Huh, D.1
  • 110
    • 34250660588 scopus 로고    scopus 로고
    • Physiological 3D tissue model of the airway wall and mucosa
    • M.M. Choe, A.A. Tomei, and M.A. Swartz Physiological 3D tissue model of the airway wall and mucosa Nat. Protoc. 1 1 2006 357 362
    • (2006) Nat. Protoc. , vol.1 , Issue.1 , pp. 357-362
    • Choe, M.M.1    Tomei, A.A.2    Swartz, M.A.3
  • 111
    • 84865121019 scopus 로고    scopus 로고
    • Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction
    • X. Huang Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction Am. J. Respir. Cell Mol. Biol. 2012
    • (2012) Am. J. Respir. Cell Mol. Biol.
    • Huang, X.1


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