-
1
-
-
0035159732
-
Role of T- and B-lymphocytes in pulmonary host defences
-
Moore BB, Moore TA, Toews GB. Role of T- and B-lymphocytes in pulmonary host defences. Eur Respir J 2001; 18:846-56.
-
(2001)
Eur Respir J
, vol.18
, pp. 846-856
-
-
Moore, B.B.1
Moore, T.A.2
Toews, G.B.3
-
2
-
-
78650015441
-
Encyclopedia of Respiratory Medicine
-
In: Laurent GL, Shapiro S, eds. Maryland Heights, MO, USA: Elsevier,
-
Lee CG, Elias JA. Transgenic models. In: Laurent GL, Shapiro S, eds. Encyclopedia of Respiratory Medicine. Maryland Heights, MO, USA: Elsevier, 2006:283-7.
-
(2006)
Transgenic models
, pp. 283-287
-
-
Lee, C.G.1
Elias, J.A.2
-
3
-
-
0037314229
-
New insights into the pathogenesis of asthma
-
Elias JA, Lee CG, Zheng T, Ma B, Homer RJ, Zhu Z. New insights into the pathogenesis of asthma. J Clin Invest 2003; 111:291-7.
-
(2003)
J Clin Invest
, vol.111
, pp. 291-297
-
-
Elias, J.A.1
Lee, C.G.2
Zheng, T.3
Ma, B.4
Homer, R.J.5
Zhu, Z.6
-
4
-
-
37349093009
-
Toll-like receptors, Notch ligands, and cytokines drive the chronicity of lung inflammation
-
Raymond T, Schaller M, Hogaboam CM, Lukacs NW, Rochford R, Kunkel SL. Toll-like receptors, Notch ligands, and cytokines drive the chronicity of lung inflammation. Proc Am Thorac Soc 2007; 4:635-41.
-
(2007)
Proc Am Thorac Soc
, vol.4
, pp. 635-641
-
-
Raymond, T.1
Schaller, M.2
Hogaboam, C.M.3
Lukacs, N.W.4
Rochford, R.5
Kunkel, S.L.6
-
5
-
-
0033923153
-
Interleukin 4 and 13 participation in mycobacterial (type-1) and schistosomal (type-2) antigen-elicited pulmonary granuloma formation: multiparameter analysis of cellular recruitment, chemokine expression and cytokine networks
-
Ruth JH, Warmington KS, Shang X, Lincoln P, Evanoff H, Kunkel SL, Chensue SW. Interleukin 4 and 13 participation in mycobacterial (type-1) and schistosomal (type-2) antigen-elicited pulmonary granuloma formation: multiparameter analysis of cellular recruitment, chemokine expression and cytokine networks. Cytokine 2000; 12:432-44.
-
(2000)
Cytokine
, vol.12
, pp. 432-444
-
-
Ruth, J.H.1
Warmington, K.S.2
Shang, X.3
Lincoln, P.4
Evanoff, H.5
Kunkel, S.L.6
Chensue, S.W.7
-
6
-
-
63549104097
-
Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma
-
Nevala WK, Vachon CM, Leontovich AA, Scott CG, Thompson MA, Markovic SN. Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma. Clin Cancer Res 2009; 15:1931-9.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1931-1939
-
-
Nevala, W.K.1
Vachon, C.M.2
Leontovich, A.A.3
Scott, C.G.4
Thompson, M.A.5
Markovic, S.N.6
-
7
-
-
4143052494
-
Innate immunity dictates cytokine polarization relevant to the development of pulmonary fibrosis
-
Strieter RM, Keane MP. Innate immunity dictates cytokine polarization relevant to the development of pulmonary fibrosis. J Clin Invest 2004; 114:165-8.
-
(2004)
J Clin Invest
, vol.114
, pp. 165-168
-
-
Strieter, R.M.1
Keane, M.P.2
-
8
-
-
2642522640
-
Genetic transformation of mouse embryos by microinjection of purified DNA
-
Gordon JW, Scangos GA, Plotkin DJ, Barbosa JA, Ruddle FH. Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci U S A 1980; 77:7380-4.
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, pp. 7380-7384
-
-
Gordon, J.W.1
Scangos, G.A.2
Plotkin, D.J.3
Barbosa, J.A.4
Ruddle, F.H.5
-
9
-
-
66149102465
-
Targeted transgenesis at the HPRT locus: an efficient strategy to achieve tightly controlled in vivo conditional expression with the tet system
-
Palais G, Nguyen Dinh Cat A, Friedman H et al. Targeted transgenesis at the HPRT locus: an efficient strategy to achieve tightly controlled in vivo conditional expression with the tet system. Physiol Genomics 2009; 37:140-6.
-
(2009)
Physiol Genomics
, vol.37
, pp. 140-146
-
-
Palais, G.1
Nguyen Dinh Cat, A.2
Friedman, H.3
-
10
-
-
0033955101
-
Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombination
-
Cvetkovic B, Yang B, Williamson RA, Sigmund CD. Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombination. J Biol Chem 2000; 275:1073-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 1073-1078
-
-
Cvetkovic, B.1
Yang, B.2
Williamson, R.A.3
Sigmund, C.D.4
-
11
-
-
65549111799
-
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells
-
Nyabi O, Naessens M, Haigh K et al. Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells. Nucleic Acids Res 2009; 37:e55.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Nyabi, O.1
Naessens, M.2
Haigh, K.3
-
12
-
-
78650009412
-
High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi
-
Hohenstein P, Slight J, Ozdemir DD, Burn SF, Berry R, Hastie ND. High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi. Pathogenetics 2008; 1:3.
-
(2008)
Pathogenetics
, vol.1
, pp. 3
-
-
Hohenstein, P.1
Slight, J.2
Ozdemir, D.D.3
Burn, S.F.4
Berry, R.5
Hastie, N.D.6
-
13
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999; 21:70-1.
-
(1999)
Nat Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
14
-
-
0034606218
-
Interferon γ induction of pulmonary emphysema in the adult murine lung
-
Wang Z, Zheng T, Zhu Z, Homer RJ, Riese RJ, Chapman HA Jr, Shapiro SD, Elias JA. Interferon γ induction of pulmonary emphysema in the adult murine lung. J Exp Med 2000; 192:1587-600.
-
(2000)
J Exp Med
, vol.192
, pp. 1587-1600
-
-
Wang, Z.1
Zheng, T.2
Zhu, Z.3
Homer, R.J.4
Riese, R.J.5
Chapman Jr, H.A.6
Shapiro, S.D.7
Elias, J.A.8
-
15
-
-
33749370410
-
IL-12 overexpression in mice as a model for Sjögren lung disease
-
McGrath-Morrow S, Laube B, Tzou SC, Cho C, Cleary J, Kimura H, Rose NR, Caturegli P. IL-12 overexpression in mice as a model for Sjögren lung disease. Am J Physiol Lung Cell Mol Physiol 2006; 291:L837-46.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
McGrath-Morrow, S.1
Laube, B.2
Tzou, S.C.3
Cho, C.4
Cleary, J.5
Kimura, H.6
Rose, N.R.7
Caturegli, P.8
-
16
-
-
16044371529
-
Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity
-
Rankin JA, Picarella DE, Geba GP et al. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci U S A 1996; 93:7821-5.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 7821-7825
-
-
Rankin, J.A.1
Picarella, D.E.2
Geba, G.P.3
-
17
-
-
33646407318
-
Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis
-
Ma B, Blackburn MR, Lee CG et al. Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. J Clin Invest 2006; 116:1274-83.
-
(2006)
J Clin Invest
, vol.116
, pp. 1274-1283
-
-
Ma, B.1
Blackburn, M.R.2
Lee, C.G.3
-
18
-
-
17444454662
-
Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma
-
Lee JJ, McGarry MP, Farmer SC et al. Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma. J Exp Med 1997; 185:2143-56.
-
(1997)
J Exp Med
, vol.185
, pp. 2143-2156
-
-
Lee, J.J.1
McGarry, M.P.2
Farmer, S.C.3
-
19
-
-
0036141448
-
Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology
-
Temann UA, Ray P, Flavell RA. Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology. J Clin Invest 2002; 109:29-39.
-
(2002)
J Clin Invest
, vol.109
, pp. 29-39
-
-
Temann, U.A.1
Ray, P.2
Flavell, R.A.3
-
20
-
-
0037144530
-
Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways
-
Lee CG, Homer RJ, Cohn L et al. Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways. J Biol Chem 2002; 277:35466-74.
-
(2002)
J Biol Chem
, vol.277
, pp. 35466-35474
-
-
Lee, C.G.1
Homer, R.J.2
Cohn, L.3
-
21
-
-
12144257806
-
Immunoregulatory effects of regulated, lung-targeted expression of IL-10 in vivo
-
Spight D, Zhao B, Haas M, Wert S, Denenberg A, Shanley TP. Immunoregulatory effects of regulated, lung-targeted expression of IL-10 in vivo. Am J Physiol Lung Cell Mol Physiol 2005; 288:L251-65.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.288
-
-
Spight, D.1
Zhao, B.2
Haas, M.3
Wert, S.4
Denenberg, A.5
Shanley, T.P.6
-
22
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999; 103:779-88.
-
(1999)
J Clin Invest
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
Zhang, Y.7
Elias, J.A.8
-
23
-
-
0037338023
-
Transgenic modeling of interleukin-13 in the lung
-
Elias JA, Zheng T, Lee CG, Homer RJ, Chen Q, Ma B, Blackburn M, Zhu Z. Transgenic modeling of interleukin-13 in the lung. Chest 2003; 3(Suppl):339S-45S.
-
(2003)
Chest
, vol.3
, Issue.SUPPL.
-
-
Elias, J.A.1
Zheng, T.2
Lee, C.G.3
Homer, R.J.4
Chen, Q.5
Ma, B.6
Blackburn, M.7
Zhu, Z.8
-
24
-
-
33645796414
-
Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling
-
Ma B, Liu W, Homer RJ, Lee PJ, Coyle AJ, Lora JM, Lee CG, Elias JA. Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol 2006; 176:4968-78.
-
(2006)
J Immunol
, vol.176
, pp. 4968-4978
-
-
Ma, B.1
Liu, W.2
Homer, R.J.3
Lee, P.J.4
Coyle, A.J.5
Lora, J.M.6
Lee, C.G.7
Elias, J.A.8
-
25
-
-
0037087365
-
IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling
-
Zhu Z, Ma B, Zheng T, Homer RJ, Lee CG, Charo IF, Noble P, Elias JA. IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol 2002; 168:2953-62.
-
(2002)
J Immunol
, vol.168
, pp. 2953-2962
-
-
Zhu, Z.1
Ma, B.2
Zheng, T.3
Homer, R.J.4
Lee, C.G.5
Charo, I.F.6
Noble, P.7
Elias, J.A.8
-
27
-
-
0042388120
-
Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway
-
Blackburn MR, Lee CG, Young HW, Zhu Z, Chunn JL, Kang MJ, Banerjee SK, Elias JA. Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. J Clin Invest 2003; 112:332-44.
-
(2003)
J Clin Invest
, vol.112
, pp. 332-344
-
-
Blackburn, M.R.1
Lee, C.G.2
Young, H.W.3
Zhu, Z.4
Chunn, J.L.5
Kang, M.J.6
Banerjee, S.K.7
Elias, J.A.8
-
28
-
-
0036679426
-
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling
-
Lanone S, Zheng T, Zhu Z et al. Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling. J Clin Invest 2002; 110:463-74.
-
(2002)
J Clin Invest
, vol.110
, pp. 463-474
-
-
Lanone, S.1
Zheng, T.2
Zhu, Z.3
-
29
-
-
7044260315
-
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung
-
Lee CG, Link H, Baluk P et al. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med 2004; 10:1095-103.
-
(2004)
Nat Med
, vol.10
, pp. 1095-1103
-
-
Lee, C.G.1
Link, H.2
Baluk, P.3
-
31
-
-
33748588423
-
+ T helper cells
-
+ T helper cells. Cell 2006; 126:1121-33.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
32
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H, Li Z, Yang XO et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005; 6:1133-41.
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
-
33
-
-
43549110961
-
Regulation of inflammatory responses by IL-17F
-
Yang XO, Chang SH, Park H et al. Regulation of inflammatory responses by IL-17F. J Exp Med 2008; 205:1063-75.
-
(2008)
J Exp Med
, vol.205
, pp. 1063-1075
-
-
Yang, X.O.1
Chang, S.H.2
Park, H.3
-
34
-
-
17944364849
-
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense
-
Ye P, Rodriguez FH, Kanaly S et al. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J Exp Med 2001; 194:519-27.
-
(2001)
J Exp Med
, vol.194
, pp. 519-527
-
-
Ye, P.1
Rodriguez, F.H.2
Kanaly, S.3
-
35
-
-
33846456273
-
IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection
-
Wu Q, Martin RJ, Rino JG, Breed R, Torres RM, Chu HW. IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes Infect 2007; 9:78-86.
-
(2007)
Microbes Infect
, vol.9
, pp. 78-86
-
-
Wu, Q.1
Martin, R.J.2
Rino, J.G.3
Breed, R.4
Torres, R.M.5
Chu, H.W.6
-
36
-
-
34447281733
-
Interleukin 25 promotes the initiation of proallergic type 2 responses
-
Angkasekwinai P, Park H, Wang YH, Chang SH, Corry DB, Liu YJ, Zhu Z, Dong C. Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med 2007; 204:1509-17.
-
(2007)
J Exp Med
, vol.204
, pp. 1509-1517
-
-
Angkasekwinai, P.1
Park, H.2
Wang, Y.H.3
Chang, S.H.4
Corry, D.B.5
Liu, Y.J.6
Zhu, Z.7
Dong, C.8
-
37
-
-
0030068217
-
Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
-
JID - 7505876
-
Hilton DJ, Zhang JG, Metcalf D, Alexander WS, Nicola NA, Willson TA. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc Natl Acad Sci U S A JID - 7505876 1996; 93:497-501.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 497-501
-
-
Hilton, D.J.1
Zhang, J.G.2
Metcalf, D.3
Alexander, W.S.4
Nicola, N.A.5
Willson, T.A.6
-
38
-
-
0028917463
-
Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common γ chain shared by receptors for interleukins 2, 4, 7, 9, and 15
-
Obiri NI, Debinski W, Leonard WJ, Puri RK. Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common γ chain shared by receptors for interleukins 2, 4, 7, 9, and 15. J Biol Chem 1995; 270:15.
-
(1995)
J Biol Chem
, vol.270
, pp. 15
-
-
Obiri, N.I.1
Debinski, W.2
Leonard, W.J.3
Puri, R.K.4
-
39
-
-
33744919804
-
IL-4 receptor α is an important modulator of IL-4 and IL-13 receptor binding: implications for the development of therapeutic targets
-
Andrews AL, Holloway JW, Holgate ST, Davies DE. IL-4 receptor α is an important modulator of IL-4 and IL-13 receptor binding: implications for the development of therapeutic targets. J Immunol 2006; 176:7456-61.
-
(2006)
J Immunol
, vol.176
, pp. 7456-7461
-
-
Andrews, A.L.1
Holloway, J.W.2
Holgate, S.T.3
Davies, D.E.4
-
40
-
-
0037195960
-
Kinetic analysis of the interleukin-13 receptor complex
-
Andrews AL, Holloway JW, Puddicombe SM, Holgate ST, Davies DE. Kinetic analysis of the interleukin-13 receptor complex. J Biol Chem 2002; 277:46073-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 46073-46078
-
-
Andrews, A.L.1
Holloway, J.W.2
Puddicombe, S.M.3
Holgate, S.T.4
Davies, D.E.5
-
41
-
-
70349330351
-
Cytoplasmic tail of IL-13Rα2 regulates IL-4 signal transduction
-
Andrews AL, Nordgren IK, Kirby I, Holloway JW, Holgate ST, Davies DE, Tavassoli A. Cytoplasmic tail of IL-13Rα2 regulates IL-4 signal transduction. Biochem Soc Trans 2009; 37(Pt 4):873-6.
-
(2009)
Biochem Soc Trans
, vol.37
, Issue.PART 4
, pp. 873-876
-
-
Andrews, A.L.1
Nordgren, I.K.2
Kirby, I.3
Holloway, J.W.4
Holgate, S.T.5
Davies, D.E.6
Tavassoli, A.7
-
42
-
-
44449167278
-
Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis
-
Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME. Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis. Proc Natl Acad Sci U S A 2008; 105:7240-5.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 7240-7245
-
-
Munitz, A.1
Brandt, E.B.2
Mingler, M.3
Finkelman, F.D.4
Rothenberg, M.E.5
-
43
-
-
37349073223
-
Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain
-
Ramalingam TR, Pesce JT, Sheikh F et al. Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain. Nat Immunol 2008; 9:25-33.
-
(2008)
Nat Immunol
, vol.9
, pp. 25-33
-
-
Ramalingam, T.R.1
Pesce, J.T.2
Sheikh, F.3
-
44
-
-
0033010373
-
The IL-4 receptor: signaling mechanisms and biologic functions
-
Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE. The IL-4 receptor: signaling mechanisms and biologic functions. Annu Rev Immunol 1999; 17:701-38.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 701-738
-
-
Nelms, K.1
Keegan, A.D.2
Zamorano, J.3
Ryan, J.J.4
Paul, W.E.5
-
45
-
-
58749091674
-
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways
-
Wills-Karp M, Finkelman FD. Untangling the complex web of IL-4- and IL-13-mediated signaling pathways. Sci Signal 2008; 1:pe55.
-
(2008)
Sci Signal
, vol.1
-
-
Wills-Karp, M.1
Finkelman, F.D.2
-
46
-
-
0037393323
-
IL-13 receptors and signaling pathways: an evolving web
-
Hershey GK. IL-13 receptors and signaling pathways: an evolving web. J Allergy Clin Immunol 2003; 111:677-90.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 677-690
-
-
Hershey, G.K.1
-
47
-
-
0033564686
-
Differences between IL-4- and IL-4 receptor α-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling
-
Mohrs M, Ledermann B, Kohler G, Dorfmuller A, Gessner A, Brombacher F. Differences between IL-4- and IL-4 receptor α-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling. J Immunol 1999; 162:7302-8.
-
(1999)
J Immunol
, vol.162
, pp. 7302-7308
-
-
Mohrs, M.1
Ledermann, B.2
Kohler, G.3
Dorfmuller, A.4
Gessner, A.5
Brombacher, F.6
-
48
-
-
0032554784
-
Differences between IL-4R α-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses
-
Barner M, Mohrs M, Brombacher F, Kopf M. Differences between IL-4R α-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Curr Biol 1998; 8:669-72.
-
(1998)
Curr Biol
, vol.8
, pp. 669-672
-
-
Barner, M.1
Mohrs, M.2
Brombacher, F.3
Kopf, M.4
-
49
-
-
0032167603
-
The murine IL-13 receptor α2: molecular cloning, characterization, and comparison with murine IL-13 receptor α1
-
Donaldson DD, Whitters MJ, Fitz LJ et al. The murine IL-13 receptor α2: molecular cloning, characterization, and comparison with murine IL-13 receptor α1. J Immunol 1998; 161:2317-24.
-
(1998)
J Immunol
, vol.161
, pp. 2317-2324
-
-
Donaldson, D.D.1
Whitters, M.J.2
Fitz, L.J.3
-
50
-
-
0035353154
-
The interleukin-13 receptor α2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway
-
Kawakami K, Taguchi J, Murata T, Puri RK. The interleukin-13 receptor α2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway. Blood 2001; 97:2673-9.
-
(2001)
Blood
, vol.97
, pp. 2673-2679
-
-
Kawakami, K.1
Taguchi, J.2
Murata, T.3
Puri, R.K.4
-
51
-
-
40449124503
-
IL-13 receptor α2 selectively inhibits IL-13-induced responses in the murine lung
-
Zheng T, Liu W, Oh SY et al. IL-13 receptor α2 selectively inhibits IL-13-induced responses in the murine lung. J Immunol 2008; 180:522-9.
-
(2008)
J Immunol
, vol.180
, pp. 522-529
-
-
Zheng, T.1
Liu, W.2
Oh, S.Y.3
-
52
-
-
0037451128
-
Regulation and function of the interleukin 13 receptor α2 during a T helper cell type 2-dominant immune response
-
Chiaramonte MG, Mentink-Kane M, Jacobson BA et al. Regulation and function of the interleukin 13 receptor α2 during a T helper cell type 2-dominant immune response. J Exp Med 2003; 197:687-701.
-
(2003)
J Exp Med
, vol.197
, pp. 687-701
-
-
Chiaramonte, M.G.1
Mentink-Kane, M.2
Jacobson, B.A.3
-
53
-
-
44849117539
-
Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
-
Kondo Y, Yoshimoto T, Yasuda K et al. Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int Immunol 2008; 20:791-800.
-
(2008)
Int Immunol
, vol.20
, pp. 791-800
-
-
Kondo, Y.1
Yoshimoto, T.2
Yasuda, K.3
-
54
-
-
44649129170
-
A novel IL-1 family cytokine, IL-33, potently activates human eosinophils
-
Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J Allergy Clin Immunol 2008;121:1484-90.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 1484-1490
-
-
Cherry, W.B.1
Yoon, J.2
Bartemes, K.R.3
Iijima, K.4
Kita, H.5
-
55
-
-
58149300244
-
+ T cells and promotes allergic-induced airway inflammation independent of IL-4
-
+ T cells and promotes allergic-induced airway inflammation independent of IL-4. J Immunol 2008; 181:4780-90.
-
(2008)
J Immunol
, vol.181
, pp. 4780-4790
-
-
Kurowska-Stolarska, M.1
Kewin, P.2
Murphy, G.3
-
56
-
-
75149148187
-
IL-33 receptor (T1/ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii
-
Jones LA, Roberts F, Nickdel MB, Brombacher F, McKenzie AN, Henriquez FL, Alexander J, Roberts CW. IL-33 receptor (T1/ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii. Eur J Immunol 2010; 40:426-36.
-
(2010)
Eur J Immunol
, vol.40
, pp. 426-436
-
-
Jones, L.A.1
Roberts, F.2
Nickdel, M.B.3
Brombacher, F.4
McKenzie, A.N.5
Henriquez, F.L.6
Alexander, J.7
Roberts, C.W.8
-
57
-
-
77956467548
-
Characterization of ST2 transgenic mice with resistance to IL-33
-
Ohto-Ozaki H, Kuroiwa K, Mato N, Matsuyama Y, Hayakawa M, Tamemoto H, Tominaga SI. Characterization of ST2 transgenic mice with resistance to IL-33. Eur J Immunol 2010; 40:2632-42.
-
(2010)
Eur J Immunol
, vol.40
, pp. 2632-2642
-
-
Ohto-Ozaki, H.1
Kuroiwa, K.2
Mato, N.3
Matsuyama, Y.4
Hayakawa, M.5
Tamemoto, H.6
Tominaga, S.I.7
-
58
-
-
68949181883
-
TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
-
Garlanda C, Anders HJ, Mantovani A. TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol 2009; 30:439-46.
-
(2009)
Trends Immunol
, vol.30
, pp. 439-446
-
-
Garlanda, C.1
Anders, H.J.2
Mantovani, A.3
-
59
-
-
64849087206
-
The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response
-
Bulek K, Swaidani S, Qin J et al. The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response. J Immunol 2009; 182:2601-9.
-
(2009)
J Immunol
, vol.182
, pp. 2601-2609
-
-
Bulek, K.1
Swaidani, S.2
Qin, J.3
-
60
-
-
0037100265
-
Cutting edge: changes in histone acetylation at the IL-4 and IFN-γ loci accompany Th1/Th2 differentiation
-
Fields PE, Kim ST, Flavell RA. Cutting edge: changes in histone acetylation at the IL-4 and IFN-γ loci accompany Th1/Th2 differentiation. J Immunol 2002; 169:647-50.
-
(2002)
J Immunol
, vol.169
, pp. 647-650
-
-
Fields, P.E.1
Kim, S.T.2
Flavell, R.A.3
-
61
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000; 100:655-69.
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
62
-
-
0347994894
-
Antigen-driven effector CD8 T cell function regulated by T-bet
-
Sullivan BM, Juedes A, Szabo SJ, Von Herrath M, Glimcher LH. Antigen-driven effector CD8 T cell function regulated by T-bet. Proc Natl Acad Sci U S A 2003; 100:15818-23.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15818-15823
-
-
Sullivan, B.M.1
Juedes, A.2
Szabo, S.J.3
Von Herrath, M.4
Glimcher, L.H.5
-
63
-
-
0030764961
-
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
-
Zhang DH, Cohn L, Ray P, Bottomly K, Ray A. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J Biol Chem 1997; 272:21597-603.
-
(1997)
J Biol Chem
, vol.272
, pp. 21597-21603
-
-
Zhang, D.H.1
Cohn, L.2
Ray, P.3
Bottomly, K.4
Ray, A.5
-
64
-
-
1242274405
-
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
-
Pai SY, Truitt ML, Ho IC. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci U S A 2004; 101:1993-8.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1993-1998
-
-
Pai, S.Y.1
Truitt, M.L.2
Ho, I.C.3
-
65
-
-
9244263631
-
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses
-
Zhu J, Min B, Hu-Li J et al. Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol 2004; 5:1157-65.
-
(2004)
Nat Immunol
, vol.5
, pp. 1157-1165
-
-
Zhu, J.1
Min, B.2
Hu-Li, J.3
-
66
-
-
1342321662
-
GATA-3 in human T cell helper type 2 development
-
Skapenko A, Leipe J, Niesner U et al. GATA-3 in human T cell helper type 2 development. J Exp Med 2004; 199:423-8.
-
(2004)
J Exp Med
, vol.199
, pp. 423-428
-
-
Skapenko, A.1
Leipe, J.2
Niesner, U.3
-
67
-
-
0033973582
-
Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
-
Ouyang W, Lohning M, Gao Z, Assenmacher M, Ranganath S, Radbruch A, Murphy KM. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment. Immunity 2000; 12:27-37.
-
(2000)
Immunity
, vol.12
, pp. 27-37
-
-
Ouyang, W.1
Lohning, M.2
Gao, Z.3
Assenmacher, M.4
Ranganath, S.5
Radbruch, A.6
Murphy, K.M.7
-
68
-
-
0035879115
-
Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo
-
Nawijn MC, Dingjan GM, Ferreira R, Lambrecht BN, Karis A, Grosveld F, Savelkoul H, Hendriks RW. Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo. J Immunol 2001; 167:724-32.
-
(2001)
J Immunol
, vol.167
, pp. 724-732
-
-
Nawijn, M.C.1
Dingjan, G.M.2
Ferreira, R.3
Lambrecht, B.N.4
Karis, A.5
Grosveld, F.6
Savelkoul, H.7
Hendriks, R.W.8
-
69
-
-
22044443908
-
Immune responses to Nippostrongylus brasiliensis and tuberculin protein in GATA-3-transgenic mice
-
Ozawa H, Tamauchi H, Ito M, Terashima M, Inoue M, Hozumi K, Habu S, Watanabe N. Immune responses to Nippostrongylus brasiliensis and tuberculin protein in GATA-3-transgenic mice. Immunol Lett 2005; 99:228-35.
-
(2005)
Immunol Lett
, vol.99
, pp. 228-235
-
-
Ozawa, H.1
Tamauchi, H.2
Ito, M.3
Terashima, M.4
Inoue, M.5
Hozumi, K.6
Habu, S.7
Watanabe, N.8
-
70
-
-
0037639876
-
Th2 immune responses in GATA-3-transgenic mice infected with Heligmosomoides polygyrus
-
JID - 9211652
-
Watanabe N, Tamauchi H, Ozawa H, Ito MF, Ovary Z, Habu S. Th2 immune responses in GATA-3-transgenic mice infected with Heligmosomoides polygyrus. Int Arch Allergy Immunol JID - 9211652 2003; 131(Suppl 1):11-4.
-
(2003)
Int Arch Allergy Immunol
, vol.131
, Issue.SUPPL. 1
, pp. 11-14
-
-
Watanabe, N.1
Tamauchi, H.2
Ozawa, H.3
Ito, M.F.4
Ovary, Z.5
Habu, S.6
-
71
-
-
33744829230
-
Involvement of GATA-3-dependent Th2 lymphocyte activation in airway hyperresponsiveness
-
Yamashita N, Tashimo H, Ishida H et al. Involvement of GATA-3-dependent Th2 lymphocyte activation in airway hyperresponsiveness. Am J Physiol Lung Cell Mol Physiol 2006; 290:L1045-51.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Yamashita, N.1
Tashimo, H.2
Ishida, H.3
-
72
-
-
36249026516
-
Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis
-
Matsuno Y, Ishii Y, Yoh K et al. Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis. Am J Respir Crit Care Med 2007; 176:1015-25.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 1015-1025
-
-
Matsuno, Y.1
Ishii, Y.2
Yoh, K.3
-
73
-
-
0032538985
-
c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms
-
Ho IC, Lo D, Glimcher LH. c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms. J Exp Med 1998; 188:1859-66.
-
(1998)
J Exp Med
, vol.188
, pp. 1859-1866
-
-
Ho, I.C.1
Lo, D.2
Glimcher, L.H.3
-
75
-
-
33745748325
-
Transcription factors T-bet and GATA-3 regulate development of airway remodeling
-
JID - 9421642
-
Kiwamoto T, Ishii Y, Morishima Y et al. Transcription factors T-bet and GATA-3 regulate development of airway remodeling. Am J Respir Crit Care Med JID - 9421642 2006; 174:141-51.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 141-151
-
-
Kiwamoto, T.1
Ishii, Y.2
Morishima, Y.3
-
76
-
-
0037117557
-
T-bet regulates IgG class switching and pathogenic autoantibody production
-
Peng SL, Szabo SJ, Glimcher LH. T-bet regulates IgG class switching and pathogenic autoantibody production. Proc Natl Acad Sci U S A 2002; 99:5545-50.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 5545-5550
-
-
Peng, S.L.1
Szabo, S.J.2
Glimcher, L.H.3
-
77
-
-
33845949008
-
Th1 and type 1 cytotoxic T cells dominate responses in T-bet overexpression transgenic mice that develop contact dermatitis
-
Ishizaki K, Yamada A, Yoh K et al. Th1 and type 1 cytotoxic T cells dominate responses in T-bet overexpression transgenic mice that develop contact dermatitis. J Immunol 2007; 178:605-12.
-
(2007)
J Immunol
, vol.178
, pp. 605-612
-
-
Ishizaki, K.1
Yamada, A.2
Yoh, K.3
-
78
-
-
66349134549
-
Overexpression of T-bet in T cells accelerates autoimmune glomerulonephritis in mice with a dominant Th1 background
-
Shimohata H, Yamada A, Yoh K, Ishizaki K, Morito N, Yamagata K, Takahashi S. Overexpression of T-bet in T cells accelerates autoimmune glomerulonephritis in mice with a dominant Th1 background. J Nephrol 2009; 22:123-9.
-
(2009)
J Nephrol
, vol.22
, pp. 123-129
-
-
Shimohata, H.1
Yamada, A.2
Yoh, K.3
Ishizaki, K.4
Morito, N.5
Yamagata, K.6
Takahashi, S.7
-
79
-
-
77953442986
-
Foxa2 programs Th2 cell-mediated innate immunity in the developing lung
-
Chen G, Wan H, Luo F, Zhang L, Xu Y, Lewkowich I, Wills-Karp M, Whitsett JA. Foxa2 programs Th2 cell-mediated innate immunity in the developing lung. J Immunol 2010; 184:6133-41.
-
(2010)
J Immunol
, vol.184
, pp. 6133-6141
-
-
Chen, G.1
Wan, H.2
Luo, F.3
Zhang, L.4
Xu, Y.5
Lewkowich, I.6
Wills-Karp, M.7
Whitsett, J.A.8
-
80
-
-
33746342994
-
+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
-
+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 2006; 212:8-27.
-
(2006)
Immunol Rev
, vol.212
, pp. 8-27
-
-
Sakaguchi, S.1
Ono, M.2
Setoguchi, R.3
-
81
-
-
33744984785
-
Th17: an effector CD4 T cell lineage with regulatory T cell ties
-
Weaver CT, Harrington LE, Mangan PR, Gavrieli M, Murphy KM. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 2006; 24:677-88.
-
(2006)
Immunity
, vol.24
, pp. 677-688
-
-
Weaver, C.T.1
Harrington, L.E.2
Mangan, P.R.3
Gavrieli, M.4
Murphy, K.M.5
-
82
-
-
70049101558
-
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
-
Yu D, Rao S, Tsai LM et al. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity 2009; 31:457-68.
-
(2009)
Immunity
, vol.31
, pp. 457-468
-
-
Yu, D.1
Rao, S.2
Tsai, L.M.3
-
83
-
-
33847343549
-
Retinoid-related orphan receptor γ controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen
-
Tilley SL, Jaradat M, Stapleton C et al. Retinoid-related orphan receptor γ controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen. J Immunol 2007; 178:3208-18.
-
(2007)
J Immunol
, vol.178
, pp. 3208-3218
-
-
Tilley, S.L.1
Jaradat, M.2
Stapleton, C.3
-
84
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J, Owyang A, Oldham E et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005; 23:479-90.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
|