Bronchial epithelial spheroids: an alternative culture model to investigate epithelium inflammation-mediated COPD

Respiratory Research

Volumn 8, Issue , 2007, Pages

  Deslee, Gaetan ^a   Dury, Sandra ^a   Perotin, Jeanne M ^a   Al Alam, Denise ^b   Vitry, Fabien ^a   Boxio, Rachel ^a   Gangloff, Sophie C ^b   Guenounou, Moncef ^b   Lebargy, François ^a   Belaaouaj, Abderrazzaq ^a  

^a HÔPITAL MAISON BLANCHE   (France)

^b UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BRONCHUS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CULTURE TECHNIQUE; HUMAN; METHODOLOGY; MULTICELLULAR SPHEROID; PATHOLOGY; PNEUMONIA; RESPIRATORY TRACT MUCOSA;

BRONCHI; CELL CULTURE TECHNIQUES; HUMANS; PNEUMONIA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; SPHEROIDS, CELLULAR;

EID: 40549117517     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-8-86     Document Type: Article

References (51)

1. Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS, . GOLD Scientific Committee Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 2001, 163:1256-1276. GOLD Scientific Committee.
2. Celli BR, MacNee W, . ATS/ERS Task Force Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 2004, 23:932-946. ATS/ERS Task Force.
3. Donaldson GC, Seemungal TA, Bhowmik A, Wedzicha JA. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002, 57:847-852. 10.1136/thorax.57.10.847, 12324669.
4. Halpin DM, Miravittles M. Chronic obstructive pulmonary disease: the disease and its burden to society. Proc Am Thorac Soc 2006, 3:619-623. 10.1513/pats.200603-093SS, 16963544.
5. Saetta M, Turato G, Maestrelli P, Mapp CE, Fabbri LM. Cellular and structural bases of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001, 163:1304-1309.
6. Shapiro SD, Ingenito EP. The pathogenesis of chronic obstructive pulmonary disease. Advances in the past 100 years. Am J Respir Cell Mol Biol 2005, 32:367-372. 10.1165/rcmb.F296, 15837726.
7. Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004, 364:709-721. 10.1016/S0140-6736(04)16900-6, 15325838.
8. MacNee W. Pathogenesis of obstructive pulmonary disease. Proc Am Thor Soc 2005, 2:258-266.
9. Rusznak C, Mills PR, Devalia JL, Sapsford RJ, Davies RJ, Lozewicz S. Effect of cigarette smoke on the permeability and IL-1 beta and sICAM-1 release from cultured human bronchial epithelial cells of never-smokers, smokers, and patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2000, 23:530-536.
10. Cromwell O, Hamid Q, Corrigan CJ, Barkans J, Meng Q, Collins PD, Kay AB. Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1 beta and tumor necrosis factor-alpha. Immunology 1992, 77:330-337. 1421719, 1478679.
11. Patel IS, Roberts NJ, Lloyd-Owen SJ, Sapsford RJ, Wedzicha JA. Airway epithelial inflammatory responses and clinical parameters in COPD. Eur Respir J 2003, 22:94-99. 10.1183/09031936.03.00093703, 12882457.
12. Schulz C, Kratzel K, Wolf K, Schroll S, Kohler M, Pfeifer M. Activation of bronchial epithelial cells in smokers without airway obstruction and patients with COPD. Chest 2004, 125:1706-1713. 10.1378/chest.125.5.1706, 15136380.
13. Profita M, Chiappara G, Mirabella F, Di Giorgi R, Chimenti L, Costanzo G, Riccobono L, Bellia V, Bousquet J, Vignola AM. Effect of cilomilast (Ariflo) on TNF-alpha, IL-8 and GM-CSF release by airway cells of patients with COPD. Thorax 2003, 58:573-579. 10.1136/thorax.58.7.573, 12832668.
14. Denning GM, Wollenweber LA, Railsback MA, Cox CD, Stoll LL, Britigan BE. Pseudomonas pyocianin increases interleukin-8 expression by human airway epithelial cells. Infect Immun 1998, 66:5777-5784. 108730, 9826354.
15. Khair OA, Devalia JL, Abdelaziz MM, Sapsford RJ, Tarraf H, Davies RJ. Effect of Haemophilus influenzae endotoxin on the synthesis of IL-6, IL-8, TNF-alpha and expression of ICAM-1 in cultured human bronchial epithelial cells. Eur Respir J 1994, 7:2109-2116. 10.1183/09031936.94.07122109, 7713191.
16. Palmberg L, Larsson BM, Malmberg P, Larsson K. Induction of IL-8 production in human alveolar macrophages and human bronchial epithelial cells in vitro by swine dust. Thorax 1998, 53:260-264.
17. Maestrelli P, Saetta M, Mapp CE, Fabbri LM. Remodelling in response to infection and injury. Airway inflammation and hypersecretion of mucus in smoking subjects with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001, 164:S76-80.
18. Castillon N, Hinnrasky J, Zahm JM, Kaplan H, Bonnet N, Corlieu P, Klossek JM, Taouil K, Avril-Deplanque A, Peault B, Puchelle E. Polarized expresion of cystic fibrosis transmembrane conductance regulator and associated epithelial proteins during the regeneration of human airway surface epithelium in three-dimensional culture. Lab Invest 2002, 82:989-98.
19. Carterson AJ, Höner zu Bentrup K, Ott CM, Clarke MS, Pierson DL, Vanderburg CR, Buchanan KL, Nickerson CA, Schurr MJ. A549 lung epithelial cells grown as three-dimensional aggregates: alternative tissue culture model for Pseudomonas aeruginosa pathogenesis. Inf Immun 2005, 73:1129-1140.
20. Jorissen M, Van der Schueren B, Van den Berghe H, Cassiman JJ. The preservation and regeneration of cilia on human nasal epithelial cells cultured in vitro. Arch Otorhinolaryngol 1989, 246:308-314. 10.1007/BF00463582, 2590043.
21. Castillon N, Avril-Deplanque A, Coraux C, Delenda C, Peault B, Danos O, Puchelle E. Regeneration of a well-differentiated human airway surface epithelium by spheroid and lentivirus vector-transduced airway cells. J Gene Med 2004, 6:846-856. 10.1002/jgm.570, 15293343.
22. Laoukili J, Perret E, Willems T, Minty A, Parthoens E, Houcine O, Coste A, Joressen M, Marano F, Caput D, Tournier F. IL-13 alters mucociliary differentiation and ciliary beating of human respiratory cells. J Clin Invest 2001, 108:1817-1824. 209466, 11748265, 10.1172/JCI200113557.
23. Pedersen PS, Frederiksen O, Holstein-Rathlou NH, Larsen PL, Qvortrup K. Ion transport in epithelial spheroids derived from human airway cells. Am J Physiol 1999, 276:L75-L80.
24. Bridges MA, Walker DC, Harris RA, Wilson BR, Davidson AG. Cultured human nasal epithelial multicellular spheroids: polar cyst-like model tissues. Biochem Cell Biol 1991, 69:102-108.
25. Fabbri LM, Hurd SS, . GOLD Scientific Committee Global strategy for the diagnosis, management and prevention of COPD: 2003 update. Eur Respir J 2003, 22:1-2. 10.1183/09031936.03.00063703, 12882441, GOLD Scientific Committee.
26. Celli BR, Cote CG, Marin JM, Casanova C, Montes de Oca M, Mendez RA, Pinto Plata V, Cabral HJ. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med 2004, 350:1005-1012. 10.1056/NEJMoa021322, 14999112.
27. Chevillard M, Hinnrasky J, Zahm JM, Plotowski MC, Puchelle E. Proliferation, differentiation and ciliary beating of human respiratory ciliated cells in primary culture. Cell Tissue Res 1991, 264:49-55. 10.1007/BF00305721, 2054845.
28. Evans SM, Blyth DI, Wong T, Sanjar S, West MR. Decreased distribution of lung epithelial junction proteins after intratracheal antigen or lipopolysaccharide challenge: correlation with neutrophil influx and levels of BALF sE-cadherin. Am J Respir Cell Mol Biol 2002, 27:446-454.
29. Kobayashi N, Dezawa M, Nagata H, Yuasa S, Konno A. Immunohistochemichal study of E-cadherin and ZO-1 in allergic nasal epithelium of the guinea pig. Int Arch Allergy Immunol 1998, 116:196-205. 10.1159/000023945, 9693267.
30. Jang YJ, Kim HG, Koo TW, Chung PS. Localization of ZO-1 and E-cadherin in the nasal polyp epithelium. Eur Arch Otorhinolaryngol 2002, 259:465-469.
31. Devalia JL, Sapsford RJ, Wells CW, Richman P, Davies RJ. Culture and comparison of human bronchial and nasal epithelial cells in vitro. Respir Med 1990, 84:303-312.
32. Woolhouse IS, Bayley DL, Stockley RA. Sputum chemotactic activity in chronic obstructive pulmonary disease: effect of alpha(1)-antitrypsin deficiency and the role of leukotriene B(4) and interleukin 8. Thorax 2002, 57:709-714. 10.1136/thorax.57.8.709, 12149532.
33. Beeh KM, Kornmann O, Buhl R, Culpitt SV, Giembycz MA, Barnes PJ. Neutrophil chemotactic activity of sputum from patients with COPD: role of interleukin 8 and leukotriene B4. Chest 2003, 123:1240-1247. 10.1378/chest.123.4.1240, 12684317.
34. Trudeau J, Hu H, Chibana K, Chu HW, Westcott JY, Wenzel SE. Selective downregulation of prostaglandin E2-related pathways by the Th2 cytokine IL-13. J Allergy Clin Immunol 2006, 117:1446-1454. 10.1016/j.jaci.2006.01.049, 16751012.
35. Aldonyte R, Jansson L, Piitulainen E, Janciauskiene S. Circulating monocytes from healthy subjects and COPD patients. Respir Res 2003, 4:11. 239032, 14624669, 10.1186/1465-9921-4-11.
36. Dentener MA, Louis R, Cloots RH, Henket M, Wouters EF. Differences in local versus systemic TNFalpha production in COPD: inhibitory effect of hyaluronan on LPS induced blood cell TNFalpha release. Thorax 2006, 61:478-484. 10.1136/thx.2005.053330, 16517575.
37. Chaudhuri N, Dower SK, Whyte MK, Sabroe I. Toll-like receptors and chronic lung disease. Clin Sci (London) 2005, 109:125-133. 16033327.
38. Sabroe I, Whyte MK, Wilson AG, Dower SK, Hubbard R, Hall I. Toll-like receptor (TLR) 4 polymorphisms and COPD. Thorax 2004, 59:81.
39. Berclaz PY, Carey B, Fillipi MD, Wernke-Dollries K, Geraci N, Cush S, Richardson T, Kitzmiller J, O'Connor M, Hermoyian C, Korfhagen T, Whitsett JA, Trapnell BC. GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS. Am J Respir Cell Mol Biol 2007, 36:114-121. 10.1165/rcmb.2006-0174OC, 16917076.
40. Montuschi P, Kharitonov SA, Ciabattoni G, Barnes PJ. Exhaled leukotrienes and prostaglandins in COPD. Thorax 2003, 58:585-588. 10.1136/thorax.58.7.585, 12832671.
41. Carpagnano GE, Kharitonov SA, Foschino-Barbaro MP, Resta O, Gramiccioni E, Barnes PJ. Increased inflammatory markers in the exhaled breath condensate of cigarette smokers. Eur Respir J 2003, 21:589-593.
42. Kostikas K, Gaga M, Papatheodorou G, Karamanis T, Orphanidou D, Loukides S. Leukotriene B4 in exhaled breath condensate and sputum supernatant in patients with COPD and asthma. Chest 2005, 127:1553-1559. 10.1378/chest.127.5.1553, 15888827.
43. Biernacki WA, Kharitonov SA, Barnes PJ. Increased leukotriene B4 and 8-isoprostane in exhaled breath condensate of patients with exacerbations of COPD. Thorax 2003, 58:294-298. 10.1136/thorax.58.4.294, 12668789.
44. Klockmann MT, Jahn HU, Hippenstiel S, Kramer HJ, Suttorp N. Interaction of human neutrophils with airway epithelial cells: reduction of leukotriene B4 generation by epithelial cell derived prostaglandin E2. J Cell Physiol 1998, 175:268-275. 10.1002/(SICI)1097-4652(199806)175:3<268::AID-JCP4>3.0.CO;2-M, 9572471.
45. Santus P, Sola A, Carlucci P, Fumagalli F, Di Gennaro A, Mondoni M, Carnini C, Centanni S, Sala A. Lipid peroxidation and 5-lipoxygenase activity in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2005, 171:838-843. 10.1164/rccm.200404-558OC, 15579728.
46. Hasday JD, Bascom R, Costa JJ, Fitzgerald T, Dubin W. Bacterial endotoxin is an active component of cigarette smoke. Chest 1999, 115:829-835. 10.1378/chest.115.3.829, 10084499.
47. Michel O, Nagy AM, Schroeven M, Duchateau J, Neve J, Fondu P, Sergysels R. Dose-response relationship to inhaled endotoxin in normal subjects. Am J Respir Crit Care Med 1997, 156:1157-1164.
48. Sandstrom T, Bjermer L, Rylander R. Lipopolysaccharide (LPS) inhalation in healthy subjects increases neutrophils, lymphocytes and fibronectin levels in bronchoalveolar lavage fluid. Eur Respir J 1992, 5:992-996.
49. Roos-Engstrand E, Wallin A, Bucht A, Pourazar J, Sandstrom T, Blomberg A. Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure. Eur Respir J 2005, 25:797-803. 10.1183/09031936.05.00078804, 15863635.
50. Schwartz DA, Donham KJ, Olenchock SA, Popendorf WJ, Van Fossen DS, Burmeister LF, Merchant JA. Determinants of longitudinal changes in spirometric function among swine confinement operators and farmers. Am J Respir Crit Care Med 1995, 151:47-53.
51. Vernooy JH, Dentener MA, Van Suylen RJ, Buurman WA, Wouters EF. Long-term intratracheal lipopolysaccharide exposure in mice results in chronic lung inflammation and persistent pathology. Am J Respir Cell Mol Biol 2002, 26:152-159.