Polyinosinic:polycytidylic acid induces protein kinase D-dependent disassembly of apical junctions and barrier dysfunction in airway epithelial cells

Journal of Allergy and Clinical Immunology

Volumn 128, Issue 6, 2011, Pages

  Rezaee, Fariba ^a   Meednu, Nida ^a   Emo, Jason A ^a   Saatian, Bahman ^a   Chapman, Timothy J ^a   Naydenov, Nayden G ^a   De Benedetto, Anna ^a   Beck, Lisa A ^a   Ivanov, Andrei I ^a   Georas, Steve N ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

adherens junctions; Asthma; epithelial permeability; polyI:C; protein kinase C; tight junctions; Toll like receptor 3

Indexed keywords

1 (5 IODO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BETA CATENIN; BLEBBISTATIN; DOUBLE STRANDED RNA; OCCLUDIN; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN KINASE D; PROTEIN ZO1; UVOMORULIN;

ACTIN FILAMENT; APICAL JUNCTION DISASSEMBLY; ARTICLE; BARRIER DYSFUNCTION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG ANTAGONISM; ELECTRIC RESISTANCE; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; MEMBRANE DAMAGE; MEMBRANE STRUCTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM;

EID: 82555205301     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.08.035     Document Type: Article

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