-
1
-
-
1642271442
-
Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2
-
Abu-Bakar A., Satarug S., Marks G.C., Lang M.A., Moore M.R. Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2. Toxicol. Lett. 2004, 148:199-210.
-
(2004)
Toxicol. Lett.
, vol.148
, pp. 199-210
-
-
Abu-Bakar, A.1
Satarug, S.2
Marks, G.C.3
Lang, M.A.4
Moore, M.R.5
-
2
-
-
26944445430
-
Evidence for induced microsomal bilirubin degradation by cytochrome P450 2A5
-
Abu-Bakar A., Moore M.R., Lang M.A. Evidence for induced microsomal bilirubin degradation by cytochrome P450 2A5. Biochem. Pharmacol. 2005, 70:1527-1535.
-
(2005)
Biochem. Pharmacol.
, vol.70
, pp. 1527-1535
-
-
Abu-Bakar, A.1
Moore, M.R.2
Lang, M.A.3
-
3
-
-
34247371476
-
Regulation of CYP2A5 gene by the transcription factor nuclear factor (erythroid-derived 2)-like 2
-
Abu-Bakar A., Lamsa V., Arpiainen S., Moore M.R., Lang M.A., Hakkola J. Regulation of CYP2A5 gene by the transcription factor nuclear factor (erythroid-derived 2)-like 2. Drug Metab. Dispos. 2007, 35:787-794.
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 787-794
-
-
Abu-Bakar, A.1
Lamsa, V.2
Arpiainen, S.3
Moore, M.R.4
Lang, M.A.5
Hakkola, J.6
-
4
-
-
81255211643
-
Inducible bilirubin oxidase: a novel function for the mouse cytochrome P450 2A5
-
Abu-Bakar A., Arthur D.M., Aganovic S., Ng J.C., Lang M.A. Inducible bilirubin oxidase: a novel function for the mouse cytochrome P450 2A5. Toxicol. Appl. Pharmacol. 2011, 257:14-22.
-
(2011)
Toxicol. Appl. Pharmacol.
, vol.257
, pp. 14-22
-
-
Abu-Bakar, A.1
Arthur, D.M.2
Aganovic, S.3
Ng, J.C.4
Lang, M.A.5
-
5
-
-
84860507435
-
Metabolism of bilirubin by human cytochrome P450 2A6
-
Abu-Bakar A., Arthur D.M., Wikman A.S., Rahnasto M., Juvonen R.O., Vepsalainen J., Raunio H., Ng J.C., Lang M.A. Metabolism of bilirubin by human cytochrome P450 2A6. Toxicol. Appl. Pharmacol. 2012, 261:50-58.
-
(2012)
Toxicol. Appl. Pharmacol.
, vol.261
, pp. 50-58
-
-
Abu-Bakar, A.1
Arthur, D.M.2
Wikman, A.S.3
Rahnasto, M.4
Juvonen, R.O.5
Vepsalainen, J.6
Raunio, H.7
Ng, J.C.8
Lang, M.A.9
-
6
-
-
84871281717
-
Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver
-
Abu-Bakar A., Hakkola J., Juvonen R., Rahnasto-Rilla M., Raunio H., Lang M.A. Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver. Curr. Drug Metab. 2013, 14:137-150.
-
(2013)
Curr. Drug Metab.
, vol.14
, pp. 137-150
-
-
Abu-Bakar, A.1
Hakkola, J.2
Juvonen, R.3
Rahnasto-Rilla, M.4
Raunio, H.5
Lang, M.A.6
-
7
-
-
15744390146
-
Regulation of the Cyp2a5 gene involves an aryl hydrocarbon receptor-dependent pathway
-
Arpiainen S., Raffalli-Mathieu F., Lang M.A., Pelkonen O., Hakkola J. Regulation of the Cyp2a5 gene involves an aryl hydrocarbon receptor-dependent pathway. Mol. Pharmacol. 2005, 67:1325-1333.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 1325-1333
-
-
Arpiainen, S.1
Raffalli-Mathieu, F.2
Lang, M.A.3
Pelkonen, O.4
Hakkola, J.5
-
8
-
-
34248156695
-
Aryl hydrocarbon receptor nuclear translocator and upstream stimulatory factor regulate Cytochrome P450 2a5 transcription through a common E-box site
-
Arpiainen S., Lamsa V., Pelkonen O., Yim S.H., Gonzalez F.J., Hakkola J. Aryl hydrocarbon receptor nuclear translocator and upstream stimulatory factor regulate Cytochrome P450 2a5 transcription through a common E-box site. J. Mol. Biol. 2007, 369:640-652.
-
(2007)
J. Mol. Biol.
, vol.369
, pp. 640-652
-
-
Arpiainen, S.1
Lamsa, V.2
Pelkonen, O.3
Yim, S.H.4
Gonzalez, F.J.5
Hakkola, J.6
-
9
-
-
51549103448
-
Coactivator PGC-1alpha regulates the fasting inducible xenobiotic-metabolizing enzyme CYP2A5 in mouse primary hepatocytes
-
Arpiainen S., Jarvenpaa S.M., Manninen A., Viitala P., Lang M.A., Pelkonen O., Hakkola J. Coactivator PGC-1alpha regulates the fasting inducible xenobiotic-metabolizing enzyme CYP2A5 in mouse primary hepatocytes. Toxicol. Appl. Pharmacol. 2008, 232:135-141.
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.232
, pp. 135-141
-
-
Arpiainen, S.1
Jarvenpaa, S.M.2
Manninen, A.3
Viitala, P.4
Lang, M.A.5
Pelkonen, O.6
Hakkola, J.7
-
10
-
-
0033015263
-
Predictive ability of a predischarge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns
-
Bhutani V.K., Johnson L., Sivieri E.M. Predictive ability of a predischarge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns. Pediatrics 1999, 103:6-14.
-
(1999)
Pediatrics
, vol.103
, pp. 6-14
-
-
Bhutani, V.K.1
Johnson, L.2
Sivieri, E.M.3
-
11
-
-
84857744956
-
Rescue of bilirubin-induced neonatal lethality in a mouse model of Crigler-Najjar syndrome type I by AAV9-mediated gene transfer
-
Bortolussi G., Zentilin L., Baj G., Giraudi P., Bellarosa C., Giacca M., Tiribelli C., Muro A.F. Rescue of bilirubin-induced neonatal lethality in a mouse model of Crigler-Najjar syndrome type I by AAV9-mediated gene transfer. FASEB J. 2012, 26:1052-1063.
-
(2012)
FASEB J.
, vol.26
, pp. 1052-1063
-
-
Bortolussi, G.1
Zentilin, L.2
Baj, G.3
Giraudi, P.4
Bellarosa, C.5
Giacca, M.6
Tiribelli, C.7
Muro, A.F.8
-
12
-
-
0028276410
-
Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man
-
Bosma P.J., Seppen J., Goldhoorn B., Bakker C., Oude Elferink R.P., Chowdhury J.R., Chowdhury N.R., Jansen P.L. Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man. J. Biol. Chem. 1994, 269:17960-17964.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17960-17964
-
-
Bosma, P.J.1
Seppen, J.2
Goldhoorn, B.3
Bakker, C.4
Oude Elferink, R.P.5
Chowdhury, J.R.6
Chowdhury, N.R.7
Jansen, P.L.8
-
14
-
-
5044220926
-
A link between hyperbilirubinemia, oxidative stress and injury to neocortical synaptosomes
-
Brito M.A., Brites D., Butterfield D.A. A link between hyperbilirubinemia, oxidative stress and injury to neocortical synaptosomes. Brain Res. 2004, 1026:33-43.
-
(2004)
Brain Res.
, vol.1026
, pp. 33-43
-
-
Brito, M.A.1
Brites, D.2
Butterfield, D.A.3
-
15
-
-
39749156518
-
Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid
-
Brito M.A., Lima S., Fernandes A., Falcao A.S., Silva R.F., Butterfield D.A., Brites D. Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid. Neurotoxicology 2008, 29:259-269.
-
(2008)
Neurotoxicology
, vol.29
, pp. 259-269
-
-
Brito, M.A.1
Lima, S.2
Fernandes, A.3
Falcao, A.S.4
Silva, R.F.5
Butterfield, D.A.6
Brites, D.7
-
16
-
-
36549090063
-
Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells
-
Brito M.A., Rosa A.I., Falcao A.S., Fernandes A., Silva R.F., Butterfield D.A., Brites D. Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells. Neurobiol. Dis. 2008, 29:30-40.
-
(2008)
Neurobiol. Dis.
, vol.29
, pp. 30-40
-
-
Brito, M.A.1
Rosa, A.I.2
Falcao, A.S.3
Fernandes, A.4
Silva, R.F.5
Butterfield, D.A.6
Brites, D.7
-
17
-
-
21344458602
-
Quantitative real-time RT-PCR - a perspective
-
Bustin S.A., Benes V., Nolan T., Pfaffl M.W. Quantitative real-time RT-PCR - a perspective. J. Mol. Endocrinol. 2005, 34:597-601.
-
(2005)
J. Mol. Endocrinol.
, vol.34
, pp. 597-601
-
-
Bustin, S.A.1
Benes, V.2
Nolan, T.3
Pfaffl, M.W.4
-
18
-
-
0036170810
-
The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways
-
Cai Y., Konishi T., Han G., Campwala K.H., French S.W., Wan Y.J. The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways. Eur. J. Pharm. Sci. 2002, 15:89-96.
-
(2002)
Eur. J. Pharm. Sci.
, vol.15
, pp. 89-96
-
-
Cai, Y.1
Konishi, T.2
Han, G.3
Campwala, K.H.4
French, S.W.5
Wan, Y.J.6
-
19
-
-
0030014639
-
Liver injury and expression of cytochromes P450: evidence that regulation of CYP2A5 is different from that of other major xenobiotic metabolizing CYP enzymes
-
Camus-Randon A.M., Raffalli F., Bereziat J.C., McGregor D., Konstandi M., Lang M.A. Liver injury and expression of cytochromes P450: evidence that regulation of CYP2A5 is different from that of other major xenobiotic metabolizing CYP enzymes. Toxicol. Appl. Pharmacol. 1996, 138:140-148.
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.138
, pp. 140-148
-
-
Camus-Randon, A.M.1
Raffalli, F.2
Bereziat, J.C.3
McGregor, D.4
Konstandi, M.5
Lang, M.A.6
-
20
-
-
0031418206
-
Distinct time courses of increase in cytochromes P450 1A2, 2A5 and glutathione S-transferases during the progressive hepatitis associated with Helicobacter hepaticus
-
Chomarat P., Sipowicz M.A., Diwan B.A., Fornwald L.W., Awasthi Y.C., Anver M.R., Rice J.M., Anderson L.M., Wild C.P. Distinct time courses of increase in cytochromes P450 1A2, 2A5 and glutathione S-transferases during the progressive hepatitis associated with Helicobacter hepaticus. Carcinogenesis 1997, 18:2179-2190.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2179-2190
-
-
Chomarat, P.1
Sipowicz, M.A.2
Diwan, B.A.3
Fornwald, L.W.4
Awasthi, Y.C.5
Anver, M.R.6
Rice, J.M.7
Anderson, L.M.8
Wild, C.P.9
-
21
-
-
0032551717
-
Role of bilirubin in the regulation of the total peroxyl radical trapping antioxidant activity of plasma in sickle cell disease
-
Dailly E., Urien S., Barre J., Reinert P., Tillement J.P. Role of bilirubin in the regulation of the total peroxyl radical trapping antioxidant activity of plasma in sickle cell disease. Biochem. Biophys. Res. Commun. 1998, 248:303-306.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.248
, pp. 303-306
-
-
Dailly, E.1
Urien, S.2
Barre, J.3
Reinert, P.4
Tillement, J.P.5
-
22
-
-
77951675685
-
A proteomic approach to the bilirubin-induced toxicity in neuronal cells reveals a protective function of DJ-1 protein
-
Deganuto M., Cesaratto L., Bellarosa C., Calligaris R., Vilotti S., Renzone G., Foti R., Scaloni A., Gustincich S., Quadrifoglio F., Tiribelli C., Tell G. A proteomic approach to the bilirubin-induced toxicity in neuronal cells reveals a protective function of DJ-1 protein. Proteomics 2010, 10:1645-1657.
-
(2010)
Proteomics
, vol.10
, pp. 1645-1657
-
-
Deganuto, M.1
Cesaratto, L.2
Bellarosa, C.3
Calligaris, R.4
Vilotti, S.5
Renzone, G.6
Foti, R.7
Scaloni, A.8
Gustincich, S.9
Quadrifoglio, F.10
Tiribelli, C.11
Tell, G.12
-
23
-
-
0029129079
-
Hyperbilirubinemia results in reduced oxidative injury in neonatal Gunn rats exposed to hyperoxia
-
Dennery P.A., McDonagh A.F., Spitz D.R., Rodgers P.A., Stevenson D.K. Hyperbilirubinemia results in reduced oxidative injury in neonatal Gunn rats exposed to hyperoxia. Free Radic. Biol. Med. 1995, 19:395-404.
-
(1995)
Free Radic. Biol. Med.
, vol.19
, pp. 395-404
-
-
Dennery, P.A.1
McDonagh, A.F.2
Spitz, D.R.3
Rodgers, P.A.4
Stevenson, D.K.5
-
24
-
-
33745955744
-
Plasmodium berghei (ANKA): infection induces CYP2A5 and 2E1 while depressing other CYP isoforms in the mouse liver
-
De-Oliveira A.C., Da-Matta A.C., Paumgartten F.J. Plasmodium berghei (ANKA): infection induces CYP2A5 and 2E1 while depressing other CYP isoforms in the mouse liver. Exp. Parasitol. 2006, 113:256-261.
-
(2006)
Exp. Parasitol.
, vol.113
, pp. 256-261
-
-
De-Oliveira, A.C.1
Da-Matta, A.C.2
Paumgartten, F.J.3
-
25
-
-
2442535969
-
Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells
-
Dhakshinamoorthy S., Porter A.G. Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells. J. Biol. Chem. 2004, 279:20096-20107.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20096-20107
-
-
Dhakshinamoorthy, S.1
Porter, A.G.2
-
26
-
-
79957489940
-
Neuroprotection of taurine against bilirubin-induced elevation of apoptosis and intracellular free calcium ion in vivo
-
Gao X., Yang X., Zhang B. Neuroprotection of taurine against bilirubin-induced elevation of apoptosis and intracellular free calcium ion in vivo. Toxicol. Mech. Methods 2011, 21:383-387.
-
(2011)
Toxicol. Mech. Methods
, vol.21
, pp. 383-387
-
-
Gao, X.1
Yang, X.2
Zhang, B.3
-
27
-
-
84861397542
-
Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups
-
Gazzin S., Zelenka J., Zdrahalova L., Konickova R., Zabetta C.C., Giraudi P.J., Berengeno A.L., Raseni A., Robert M.C., Vitek L., Tiribelli C. Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups. Pediatr. Res. 2012, 71:653-660.
-
(2012)
Pediatr. Res.
, vol.71
, pp. 653-660
-
-
Gazzin, S.1
Zelenka, J.2
Zdrahalova, L.3
Konickova, R.4
Zabetta, C.C.5
Giraudi, P.J.6
Berengeno, A.L.7
Raseni, A.8
Robert, M.C.9
Vitek, L.10
Tiribelli, C.11
-
28
-
-
1642579541
-
Endoplasmic reticulum stress due to altered cellular redox status positively regulates murine hepatic CYP2A5 expression
-
Gilmore W.J., Kirby G.M. Endoplasmic reticulum stress due to altered cellular redox status positively regulates murine hepatic CYP2A5 expression. J. Pharmacol. Exp. Ther. 2004, 308:600-608.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 600-608
-
-
Gilmore, W.J.1
Kirby, G.M.2
-
29
-
-
2542543703
-
Bilirubin as an antioxidant: kinetic studies of the reaction of bilirubin with peroxyl radicals in solution, micelles, and lipid bilayers
-
Hatfield G.L., Barclay L.R. Bilirubin as an antioxidant: kinetic studies of the reaction of bilirubin with peroxyl radicals in solution, micelles, and lipid bilayers. Org. Lett. 2004, 6:1539-1542.
-
(2004)
Org. Lett.
, vol.6
, pp. 1539-1542
-
-
Hatfield, G.L.1
Barclay, L.R.2
-
30
-
-
79951957030
-
Partial bile duct ligation in mice: a novel model of acute cholestasis
-
Heinrich S., Georgiev P., Weber A., Vergopoulos A., Graf R., Clavien P.-A. Partial bile duct ligation in mice: a novel model of acute cholestasis. Surgery 2011, 149:445-451.
-
(2011)
Surgery
, vol.149
, pp. 445-451
-
-
Heinrich, S.1
Georgiev, P.2
Weber, A.3
Vergopoulos, A.4
Graf, R.5
Clavien, P.-A.6
-
31
-
-
79954574488
-
Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents
-
Higgins L.G., Hayes J.D. Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents. Drug Metab. Rev. 2011, 43:92-137.
-
(2011)
Drug Metab. Rev.
, vol.43
, pp. 92-137
-
-
Higgins, L.G.1
Hayes, J.D.2
-
32
-
-
38649113944
-
Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein
-
Higgins L.G., Cavin C., Itoh K., Yamamoto M., Hayes J.D. Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein. Toxicol. Appl. Pharmacol. 2008, 226:328-337.
-
(2008)
Toxicol. Appl. Pharmacol.
, vol.226
, pp. 328-337
-
-
Higgins, L.G.1
Cavin, C.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
33
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 1999, 13:76-86.
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
34
-
-
0027952645
-
Overexpression of a cytochrome P-450 of the 2a family (Cyp2a-5) in chemically induced hepatomas from female mice
-
Jounaidi Y., Bonfils C., Perin F., Negishi M., Lange R. Overexpression of a cytochrome P-450 of the 2a family (Cyp2a-5) in chemically induced hepatomas from female mice. Eur. J. Biochem. 1994, 219:791-798.
-
(1994)
Eur. J. Biochem.
, vol.219
, pp. 791-798
-
-
Jounaidi, Y.1
Bonfils, C.2
Perin, F.3
Negishi, M.4
Lange, R.5
-
35
-
-
0022213443
-
Selective induction of coumarin 7-hydroxylase by pyrazole in D2 mice
-
Juvonen R.O., Kaipainen P.K., Lang M.A. Selective induction of coumarin 7-hydroxylase by pyrazole in D2 mice. Eur. J. Biochem. 1985, 152:3-8.
-
(1985)
Eur. J. Biochem.
, vol.152
, pp. 3-8
-
-
Juvonen, R.O.1
Kaipainen, P.K.2
Lang, M.A.3
-
36
-
-
0028114747
-
Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice
-
Kirby G.M., Chemin I., Montesano R., Chisari F.V., Lang M.A., Wild C.P. Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice. Mol. Carcinog. 1994, 11:74-80.
-
(1994)
Mol. Carcinog.
, vol.11
, pp. 74-80
-
-
Kirby, G.M.1
Chemin, I.2
Montesano, R.3
Chisari, F.V.4
Lang, M.A.5
Wild, C.P.6
-
37
-
-
0028004322
-
Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome P450 and carcinogen metabolism in male hamster liver
-
Kirby G.M., Pelkonen P., Vatanasapt V., Camus A.M., Wild C.P., Lang M.A. Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome P450 and carcinogen metabolism in male hamster liver. Mol. Carcinog. 1994, 11:81-89.
-
(1994)
Mol. Carcinog.
, vol.11
, pp. 81-89
-
-
Kirby, G.M.1
Pelkonen, P.2
Vatanasapt, V.3
Camus, A.M.4
Wild, C.P.5
Lang, M.A.6
-
38
-
-
79952797177
-
CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis
-
Kirby G.M., Nichols K.D., Antenos M. CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis. Curr. Drug Metab. 2011, 12:186-197.
-
(2011)
Curr. Drug Metab.
, vol.12
, pp. 186-197
-
-
Kirby, G.M.1
Nichols, K.D.2
Antenos, M.3
-
39
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
Kobayashi A., Kang M.-i, Okawa H., Zenke Y., Chiba T., Igarashi K., Ohtsuji M. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol. Cell. Biol. 2004, 24:7130-7139.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.-I.2
Okawa, H.3
Zenke, Y.4
Chiba, T.5
Igarashi, K.6
Ohtsuji, M.7
-
40
-
-
0031813641
-
Induction of CYP2A5 by pyrazole and its derivatives in mouse primary hepatocytes
-
Kojo A., Viitala P., Pasanen M., Pelkonen O., Raunio H., Juvonen R. Induction of CYP2A5 by pyrazole and its derivatives in mouse primary hepatocytes. Arch. Toxicol. 1998, 72:336-341.
-
(1998)
Arch. Toxicol.
, vol.72
, pp. 336-341
-
-
Kojo, A.1
Viitala, P.2
Pasanen, M.3
Pelkonen, O.4
Raunio, H.5
Juvonen, R.6
-
41
-
-
38749124436
-
Bilirubin inhibits Plasmodium falciparum growth through the generation of reactive oxygen species
-
Kumar S., Guha M., Choubey V., Maity P., Srivastava K., Puri S.K., Bandyopadhyay U. Bilirubin inhibits Plasmodium falciparum growth through the generation of reactive oxygen species. Free Radic. Biol. Med. 2008, 44:602-613.
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 602-613
-
-
Kumar, S.1
Guha, M.2
Choubey, V.3
Maity, P.4
Srivastava, K.5
Puri, S.K.6
Bandyopadhyay, U.7
-
42
-
-
80053992490
-
Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression
-
Kundu R., Dasgupta S., Biswas A., Bhattacharya S., Pal B.C., Bhattacharya S., Rao P.G., Barua N.C., Bordoloi M., Bhattacharya S. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Biochem. Pharmacol. 2011, 82:1186-1197.
-
(2011)
Biochem. Pharmacol.
, vol.82
, pp. 1186-1197
-
-
Kundu, R.1
Dasgupta, S.2
Biswas, A.3
Bhattacharya, S.4
Pal, B.C.5
Bhattacharya, S.6
Rao, P.G.7
Barua, N.C.8
Bordoloi, M.9
Bhattacharya, S.10
-
43
-
-
77952332154
-
Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver
-
Lamsa V., Levonen A.L., Leinonen H., Yla-Herttuala S., Yamamoto M., Hakkola J. Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver. Chem. Res. Toxicol. 2010, 23:977-985.
-
(2010)
Chem. Res. Toxicol.
, vol.23
, pp. 977-985
-
-
Lamsa, V.1
Levonen, A.L.2
Leinonen, H.3
Yla-Herttuala, S.4
Yamamoto, M.5
Hakkola, J.6
-
44
-
-
84867795104
-
Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2
-
Lamsa V., Levonen A.L., Sormunen R., Yamamoto M., Hakkola J. Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2. Toxicol. Sci. 2012, 130:132-144.
-
(2012)
Toxicol. Sci.
, vol.130
, pp. 132-144
-
-
Lamsa, V.1
Levonen, A.L.2
Sormunen, R.3
Yamamoto, M.4
Hakkola, J.5
-
45
-
-
0036765785
-
Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
-
Maglich J.M., Stoltz C.M., Goodwin B., Hawkins-Brown D., Moore J.T., Kliewer S.A. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol. Pharmacol. 2002, 62:638-646.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 638-646
-
-
Maglich, J.M.1
Stoltz, C.M.2
Goodwin, B.3
Hawkins-Brown, D.4
Moore, J.T.5
Kliewer, S.A.6
-
46
-
-
0022871603
-
Effect of bilirubin on the membrane potential of rat brain synaptosomes
-
Mayor F., Diez-Guerra J., Valdivieso F., Mayor F. Effect of bilirubin on the membrane potential of rat brain synaptosomes. J. Neurochem. 1986, 47:363-369.
-
(1986)
J. Neurochem.
, vol.47
, pp. 363-369
-
-
Mayor, F.1
Diez-Guerra, J.2
Valdivieso, F.3
Mayor, F.4
-
47
-
-
77953291331
-
Controversies in bilirubin biochemistry and their clinical relevance
-
McDonagh A.F. Controversies in bilirubin biochemistry and their clinical relevance. Semin. Fetal Neonatal Med. 2010, 15:141-147.
-
(2010)
Semin. Fetal Neonatal Med.
, vol.15
, pp. 141-147
-
-
McDonagh, A.F.1
-
48
-
-
0025737103
-
Regulation of mouse glutathione S-transferases by chemoprotectors. Molecular evidence for the existence of three distinct alpha-class glutathione S-transferase subunits, Ya1, Ya2, and Ya3, in mouse liver
-
McLellan L.I., Kerr L.A., Cronshaw A.D., Hayes J.D. Regulation of mouse glutathione S-transferases by chemoprotectors. Molecular evidence for the existence of three distinct alpha-class glutathione S-transferase subunits, Ya1, Ya2, and Ya3, in mouse liver. Biochem. J. 1991, 276(Pt 2):461-469.
-
(1991)
Biochem. J.
, vol.276
, Issue.PART 2
, pp. 461-469
-
-
McLellan, L.I.1
Kerr, L.A.2
Cronshaw, A.D.3
Hayes, J.D.4
-
49
-
-
20144385916
-
Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: direct cross-talk between phase I and II drug-metabolizing enzymes
-
Miao W., Hu L., Scrivens P.J., Batist G. Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: direct cross-talk between phase I and II drug-metabolizing enzymes. J. Biol. Chem. 2005, 280:20340-20348.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20340-20348
-
-
Miao, W.1
Hu, L.2
Scrivens, P.J.3
Batist, G.4
-
50
-
-
0033990325
-
Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis
-
Nebert D.W., Roe A.L., Dieter M.Z., Solis W.A., Yang Y., Dalton T.P. Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis. Biochem. Pharmacol. 2000, 59:65-85.
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 65-85
-
-
Nebert, D.W.1
Roe, A.L.2
Dieter, M.Z.3
Solis, W.A.4
Yang, Y.5
Dalton, T.P.6
-
51
-
-
0028239795
-
Free and albumin-bound bilirubin are efficient co-antioxidants for a-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation
-
Neuzil J., Stocker R. Free and albumin-bound bilirubin are efficient co-antioxidants for a-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation. J. Biol. Chem. 1994, 269:16712-16719.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16712-16719
-
-
Neuzil, J.1
Stocker, R.2
-
52
-
-
38949094972
-
Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress
-
Nichols K.D., Kirby G.M. Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress. Biochem. Pharmacol. 2008, 75:1230-1239.
-
(2008)
Biochem. Pharmacol.
, vol.75
, pp. 1230-1239
-
-
Nichols, K.D.1
Kirby, G.M.2
-
53
-
-
0024337946
-
Detection and characterization of a low affinity form of cytosolic Ah receptor in livers of mice nonresponsive to induction of cytochrome P1-450 by 3-methylcholanthrene
-
Okey A.B., Vella L.M., Harper P.A. Detection and characterization of a low affinity form of cytosolic Ah receptor in livers of mice nonresponsive to induction of cytochrome P1-450 by 3-methylcholanthrene. Mol. Pharmacol. 1989, 35:823-830.
-
(1989)
Mol. Pharmacol.
, vol.35
, pp. 823-830
-
-
Okey, A.B.1
Vella, L.M.2
Harper, P.A.3
-
54
-
-
33748920475
-
Matrix metalloproteinase-9 is an important factor in hepatic regeneration after partial hepatectomy in mice
-
Olle E.W., Ren X., McClintock S.D., Warner R.L., Deogracias M.P., Johnson K.J., Colletti L.M. Matrix metalloproteinase-9 is an important factor in hepatic regeneration after partial hepatectomy in mice. Hepatology 2006, 44:540-549.
-
(2006)
Hepatology
, vol.44
, pp. 540-549
-
-
Olle, E.W.1
Ren, X.2
McClintock, S.D.3
Warner, R.L.4
Deogracias, M.P.5
Johnson, K.J.6
Colletti, L.M.7
-
55
-
-
0016706001
-
Genetic expression of aryl hydrocarbon hydroxylase by 2,3,7,8-tetrachlorodibenzo-p-dioxin: evidence for a receptor mutation in genetically non-responsive mice
-
Poland A., Glover E. Genetic expression of aryl hydrocarbon hydroxylase by 2,3,7,8-tetrachlorodibenzo-p-dioxin: evidence for a receptor mutation in genetically non-responsive mice. Mol. Pharmacol. 1975, 11:389-398.
-
(1975)
Mol. Pharmacol.
, vol.11
, pp. 389-398
-
-
Poland, A.1
Glover, E.2
-
56
-
-
0023777834
-
Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver
-
Prochaska H.J., Talalay P. Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver. Cancer Res. 1988, 48:4776-4782.
-
(1988)
Cancer Res.
, vol.48
, pp. 4776-4782
-
-
Prochaska, H.J.1
Talalay, P.2
-
57
-
-
34748904643
-
Translational control of nrf2 protein in activation of antioxidant response by oxidants
-
Purdom-Dickinson S.E., Sheveleva E.V., Sun H., Chen Q.M. Translational control of nrf2 protein in activation of antioxidant response by oxidants. Mol. Pharmacol. 2007, 72:1074-1081.
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 1074-1081
-
-
Purdom-Dickinson, S.E.1
Sheveleva, E.V.2
Sun, H.3
Chen, Q.M.4
-
58
-
-
0036210930
-
Heterogeneous nuclear ribonucleoprotein A1 and regulation of the xenobiotic-inducible gene Cyp2a5
-
Raffalli-Mathieu F., Glisovic T., Ben-David Y., Lang M.A. Heterogeneous nuclear ribonucleoprotein A1 and regulation of the xenobiotic-inducible gene Cyp2a5. Mol. Pharmacol. 2002, 61:795-799.
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 795-799
-
-
Raffalli-Mathieu, F.1
Glisovic, T.2
Ben-David, Y.3
Lang, M.A.4
-
59
-
-
61349117533
-
Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species
-
Reisman S.A., Yeager R.L., Yamamoto M., Klaassen C.D. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species. Toxicol. Sci. 2009, 108:35-47.
-
(2009)
Toxicol. Sci.
, vol.108
, pp. 35-47
-
-
Reisman, S.A.1
Yeager, R.L.2
Yamamoto, M.3
Klaassen, C.D.4
-
61
-
-
0036073635
-
Apoptosis in murine hepatoma hepa 1c1c7 wild-type, C12, and C4 cells mediated by bilirubin
-
Seubert J.M., Darmon A.J., El-Kadi A.O., D'Souza S.J., Bend J.R. Apoptosis in murine hepatoma hepa 1c1c7 wild-type, C12, and C4 cells mediated by bilirubin. Mol. Pharmacol. 2002, 62:257-264.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 257-264
-
-
Seubert, J.M.1
Darmon, A.J.2
El-Kadi, A.O.3
D'Souza, S.J.4
Bend, J.R.5
-
62
-
-
0034857845
-
Endocytosis in rat cultured astrocytes is inhibited by unconjugated bilirubin
-
Silva R.F., Mata L.M., Gulbenkian S., Brites D. Endocytosis in rat cultured astrocytes is inhibited by unconjugated bilirubin. Neurochem. Res. 2001, 26:793-800.
-
(2001)
Neurochem. Res.
, vol.26
, pp. 793-800
-
-
Silva, R.F.1
Mata, L.M.2
Gulbenkian, S.3
Brites, D.4
-
63
-
-
0030801282
-
Increased oxidative DNA damage and hepatocyte overexpression of specific cytochrome P450 isoforms in hepatitis of mice infected with Helicobacter hepaticus
-
Sipowicz M.A., Chomarat P., Diwan B.A., Anver M.A., Awasthi Y.C., Ward J.M., Rice J.M., Kasprzak K.S., Wild C.P., Anderson L.M. Increased oxidative DNA damage and hepatocyte overexpression of specific cytochrome P450 isoforms in hepatitis of mice infected with Helicobacter hepaticus. Am. J. Pathol. 1997, 151:933-941.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 933-941
-
-
Sipowicz, M.A.1
Chomarat, P.2
Diwan, B.A.3
Anver, M.A.4
Awasthi, Y.C.5
Ward, J.M.6
Rice, J.M.7
Kasprzak, K.S.8
Wild, C.P.9
Anderson, L.M.10
-
64
-
-
0023132858
-
Bilirubin is an antioxidant of possible physiological importance
-
Stocker R., Yamamoto Y., McDonagh A. Bilirubin is an antioxidant of possible physiological importance. Science 1987, 235:1043-1046.
-
(1987)
Science
, vol.235
, pp. 1043-1046
-
-
Stocker, R.1
Yamamoto, Y.2
McDonagh, A.3
-
65
-
-
0032522541
-
Pyrazole-inducible proteins in DBA/2 mouse liver bind with high affinity to the 3'-untranslated regions of the mRNAs of coumarin hydroxylase (CYP2A5) and c-jun
-
Thulke-Gross M., Hergenhahn M., Tilloy-Ellul A., Lang M., Bartsch H. Pyrazole-inducible proteins in DBA/2 mouse liver bind with high affinity to the 3'-untranslated regions of the mRNAs of coumarin hydroxylase (CYP2A5) and c-jun. Biochem. J. 1998, 331(Pt 2):473-481.
-
(1998)
Biochem. J.
, vol.331
, Issue.PART 2
, pp. 473-481
-
-
Thulke-Gross, M.1
Hergenhahn, M.2
Tilloy-Ellul, A.3
Lang, M.4
Bartsch, H.5
-
66
-
-
4344618829
-
Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I
-
Ulvila J., Arpiainen S., Pelkonen O., Aida K., Sueyoshi T., Negishi M., Hakkola J. Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I. Biochem. J. 2004, 381:887-894.
-
(2004)
Biochem. J.
, vol.381
, pp. 887-894
-
-
Ulvila, J.1
Arpiainen, S.2
Pelkonen, O.3
Aida, K.4
Sueyoshi, T.5
Negishi, M.6
Hakkola, J.7
-
67
-
-
79956137679
-
Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin
-
Vaz A.R., Silva S.L., Barateiro A., Fernandes A., Falcao A.S., Brito M.A., Brites D. Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin. Exp. Neurol. 2011, 229:381-390.
-
(2011)
Exp. Neurol.
, vol.229
, pp. 381-390
-
-
Vaz, A.R.1
Silva, S.L.2
Barateiro, A.3
Fernandes, A.4
Falcao, A.S.5
Brito, M.A.6
Brites, D.7
-
68
-
-
0017833560
-
Hepatic accumulation and intracellular binding of conjugated bilirubin
-
Wolkoff A.W., Ketley J.N., Waggoner J.G., Berk P.D., Jakoby W.B. Hepatic accumulation and intracellular binding of conjugated bilirubin. J. Clin. Invest. 1978, 61:142-149.
-
(1978)
J. Clin. Invest.
, vol.61
, pp. 142-149
-
-
Wolkoff, A.W.1
Ketley, J.N.2
Waggoner, J.G.3
Berk, P.D.4
Jakoby, W.B.5
-
69
-
-
0018485896
-
Role of ligandin in transfer of bilirubin from plasma into liver
-
Wolkoff A.W., Goresky C.A., Sellin J., Gatmaitan Z., Arias I.M. Role of ligandin in transfer of bilirubin from plasma into liver. Am. J. Physiol. Gastrointest. Liver Physiol. 2012, 236:G638-G648.
-
(2012)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.236
-
-
Wolkoff, A.W.1
Goresky, C.A.2
Sellin, J.3
Gatmaitan, Z.4
Arias, I.M.5
-
70
-
-
79959968604
-
A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression
-
(e374)
-
Yang H., Li T.W.H., Peng J., Tang X., Ko K.S., Xia M., Aller M.A. A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression. Gastroenterology 2011, 141:378-388. (e374).
-
(2011)
Gastroenterology
, vol.141
, pp. 378-388
-
-
Yang, H.1
Li, T.W.H.2
Peng, J.3
Tang, X.4
Ko, K.S.5
Xia, M.6
Aller, M.A.7
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