Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: Involvement of transcription factor NRF2

Toxicology Letters

Volumn 148, Issue 3, 2004, Pages 199-210

  Abu Bakar, A'Edah ^a   Satarug, Soisungwan ^a   Marks, Geoffrey C ^a   Lang, Matti A ^c   Moore, Michael R ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b QUEENSLAND HEALTH   (Australia)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Cadmium; Coumarin 7 hydroxylase; Cytochrome P450 2A5; Nrf2; Stress response gene

Indexed keywords

CADMIUM; CADMIUM CHLORIDE; COUMARIN 7 HYDROXYLASE; CYTOCHROME P450 2A5; LIVER ENZYME; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; KIDNEY MICROSOME; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN INDUCTION; REACTION TIME; STRAIN DIFFERENCE; UPREGULATION;

ACUTE DISEASE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BLOTTING, NORTHERN; BLOTTING, WESTERN; CADMIUM POISONING; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY; LIVER; MALE; MICE; MICE, INBRED DBA; MICE, KNOCKOUT; MICROSOMES; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NF-E2-RELATED FACTOR 2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATORS;

EID: 1642271442     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2003.10.029     Document Type: Article

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