Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression

Biochemical Pharmacology

Volumn 82, Issue 9, 2011, Pages 1186-1197

  Kundu, Rakesh ^a   Dasgupta, Suman ^a   Biswas, Anindita ^a   Bhattacharya, Sushmita ^a   Pal, Bikas C ^b   Bhattacharya, Shelley ^a   Rao, P G ^c   Barua, N C ^c   Bordoloi, Manobjyoti ^c   Bhattacharya, Samir ^a,c  

^a VISVA BHARATI UNIVERSITY   (India)

^b INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^c CSIR NORTH EAST INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Bilirubin; Carlinoside; Liver damage; Nrf2; UGT1A1

Indexed keywords

BILIRUBIN; CARLINOSIDE; FLAVONE; GLUCURONOSYLTRANSFERASE 1A1; GLYCOSIDE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GLUCURONIDATION; HUMAN; HUMAN CELL; INTESTINE; LIVER CELL; LIVER INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT;

ANIMALS; BILIRUBIN; CARBON TETRACHLORIDE; DRUG-INDUCED LIVER INJURY; FLAVONES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCURONOSYLTRANSFERASE; GLYCOSIDES; HEP G2 CELLS; HUMANS; MOLECULAR STRUCTURE; NF-E2-RELATED FACTOR 2; PROMOTER REGIONS, GENETIC; RATS;

EID: 80053992490     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.07.069     Document Type: Article

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