Eicosapentaenoic acid and docosahexaenoic acid exert anti-inflammatory and antinociceptive effects in rodents at low doses

Nutrition Research

Volumn 33, Issue 5, 2013, Pages 422-433

  Nobre, Maria Elizabeth Pereira ^a,b   Correia, Alyne Oliveira ^a   Borges, Marília de Brito ^a   Sampaio, Thayga Maria Araújo ^a   Chakraborty, Solon Arcoverde ^a   Gonçalves, Danilo de Oliveira ^c   Brito, Gerly Anne de Castro ^c   Leal, Luzia Kalyne Almeida Moreira ^c   Felipe, Cícero Francisco Bezerra ^a   Lucetti, Daniel Luna ^a   Arida, Ricardo Mário ^b   De Barros Viana, Glauce Socorro ^a,c  

^a Faculty of Medicine Estácio of Juazeiro do Norte FMJ   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Anti inflammatory and anti nociceptive actions; Antioxidant effects; Cytotoxicity; Lipid peroxidation; Neutrophils; Omega 3 polyunsaturated fatty acids

Indexed keywords

ACETIC ACID; DEXAMETHASONE; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; INDOMETACIN; LACTATE DEHYDROGENASE; MORPHINE; MYELOPEROXIDASE; NALOXONE; OMEGA 3 FATTY ACID; PROSTAGLANDIN SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME INHIBITION; ENZYME RELEASE; EXPERIMENTAL TEST; FORMALIN TEST; HARGREAVES TEST; HOT PLATE TEST; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; LEUKOCYTE MIGRATION; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; MICROGLIA; MOUSE; NEUTROPHIL; NOCICEPTION; NOCICEPTIVE PAIN; NONHUMAN; PAW EDEMA; PERITONEAL CAVITY; PERITONITIS; PRIORITY JOURNAL; RAT; RODENT; THERMAL STIMULATION; WITHDRAWAL REFLEX; WRITHING TEST;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARRAGEENAN; CELL SURVIVAL; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; EICOSAPENTAENOIC ACID; FORMALDEHYDE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; MALE; MICE; NEUTROPHILS; NOCICEPTION; PAIN MEASUREMENT; PERITONITIS; PEROXIDASE; RATS; RATS, WISTAR; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TUMOR NECROSIS FACTOR-ALPHA;

MUS; RATTUS; RODENTIA;

EID: 84878164363     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2013.02.011     Document Type: Article

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