Pathogenesis of NSAID-induced gastric damage: Importance of cyclooxygenase inhibition and gastric hypermotility

World Journal of Gastroenterology

Volumn 18, Issue 18, 2012, Pages 2147-2160

  Takeuchi, Koji ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Gastric damage; Gastric motility; Neutrophil; Non steroidal anti inflammatory drug; Pathogenesis

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; ATROPINE; CD18 ANTIGEN; CIMETIDINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DEXAMETHASONE; DICLOFENAC; FLURBIPROFEN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; INDOMETACIN; MYELOPEROXIDASE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; ROFECOXIB; TUMOR NECROSIS FACTOR; ANTIULCER AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR;

ADRENALECTOMY; ARTHRITIS; CELL INTERACTION; CLINICAL EFFECTIVENESS; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME INHIBITION; HELICOBACTER INFECTION; HUMAN; INTESTINAL DYSMOTILITY; MEMBRANE PERMEABILITY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVIEW; RHEUMATOID ARTHRITIS; STOMACH INJURY; STOMACH MOTILITY; STOMACH PROTECTION; STOMACH ULCER; TOXICOLOGICAL PARAMETERS; UPREGULATION; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ENZYMOLOGY; GASTROINTESTINAL MOTILITY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RISK ASSESSMENT; RISK FACTOR; STOMACH MUCOSA;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; GASTRIC MUCOSA; GASTROINTESTINAL MOTILITY; HUMANS; RECEPTORS, PROSTAGLANDIN E; RISK ASSESSMENT; RISK FACTORS; STOMACH ULCER;

EID: 84866264476     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v18.i18.2147     Document Type: Review

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