-
1
-
-
0002789076
-
The Forensic Pharmacology Of Drugs Of Abuse.
-
London: Arnold
-
Drummer O, Odell M. The Forensic Pharmacology Of Drugs Of Abuse. London: Arnold, 2001.
-
(2001)
-
-
Drummer, O.1
Odell, M.2
-
2
-
-
33947489961
-
Isolation, structure and partial synthesis of an active constituent of hashish
-
Gaoni Y, Mechoulam R. Isolation, structure and partial synthesis of an active constituent of hashish. J Am Chem Soc 1964; 86:1646-1647.
-
(1964)
J Am Chem Soc
, vol.86
, pp. 1646-1647
-
-
Gaoni, Y.1
Mechoulam, R.2
-
3
-
-
18444376760
-
International union of pharmacology, XXVII. Classification of cannabinoid receptors
-
Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG. International union of pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 2002; 54: 161-202.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
Mechoulam, R.11
Pertwee, R.G.12
-
4
-
-
84886701939
-
United Nation Office on drugs and crime
-
UNODC, World Drug Report 2011, United Nation Publications
-
UNODC, World Drug Report 2011. United Nation Office on drugs and crime. United Nation Publications, 2011, 175-193.
-
(2011)
, pp. 175-193
-
-
-
6
-
-
0028323255
-
Design, synthesis and pharmacology of cannabimimetic indoles
-
Huffman JW, Dai D, Martin BR, Compton DR. Design, synthesis and pharmacology of cannabimimetic indoles. Bioorg Med Chem Lett 1994; 4:563-566.
-
(1994)
Bioorg Med Chem Lett
, vol.4
, pp. 563-566
-
-
Huffman, J.W.1
Dai, D.2
Martin, B.R.3
Compton, D.R.4
-
7
-
-
84866742397
-
A characterization of synthetic cannabinoid exposures reported to the National Poison Data System in 2010
-
Hoyte CO, Jacob J, Monte AA, Al-Jumaan M, Bronstein AC, Heard KJ. A characterization of synthetic cannabinoid exposures reported to the National Poison Data System in 2010. Ann Emerg Med 2012; 60:435-438.
-
(2012)
Ann Emerg Med
, vol.60
, pp. 435-438
-
-
Hoyte, C.O.1
Jacob, J.2
Monte, A.A.3
Al-Jumaan, M.4
Bronstein, A.C.5
Heard, K.J.6
-
8
-
-
84878034827
-
-
EMCDDA-Europol 2011 Annual Report on the implementation of Council Decision 2005/387/JHA,Accessed Feburary 21
-
EMCDDA-Europol 2011 Annual Report on the implementation of Council Decision 2005/387/JHA.http://www.emcdda.europa.eu/attachements.cfm/att_155113_EN_EMCDDA-Europol%20Annual%20Report%202011_2012_final.pdf. Accessed Feburary 21, 2013.
-
(2013)
-
-
-
9
-
-
77954954841
-
Spice drugs as a new trend: Mode of action, identification and legislation
-
Vardakou I, Pistos C, Spiliopoulou Ch. Spice drugs as a new trend: Mode of action, identification and legislation. Toxicol Lett 2010; 197:157-162.
-
(2010)
Toxicol Lett
, vol.197
, pp. 157-162
-
-
Vardakou, I.1
Pistos, C.2
Spiliopoulou, C.H.3
-
10
-
-
66249133962
-
Spice and other herbal blends: Harmless incense or cannabinoid designer drugs?
-
Auwärter V, Dresen S, Weinmann W, Mueller M, Puetz M, Ferreiros N. 'Spice' and other herbal blends: Harmless incense or cannabinoid designer drugs?. J Mass Spectrom 2009; 44:832-837.
-
(2009)
J Mass Spectrom
, vol.44
, pp. 832-837
-
-
Auwärter, V.1
Dresen, S.2
Weinmann, W.3
Mueller, M.4
Puetz, M.5
Ferreiros, N.6
-
11
-
-
84866760136
-
Analysis of synthetic cannabinoids in herbal blends by means of nano-liquid hromatography
-
Merola G, Aturkib Z, D'Oraziob G, Gottardoc R, Macchiaa T, Tagliaroc F, Fanalib S. Analysis of synthetic cannabinoids in herbal blends by means of nano-liquid hromatography. J Pharm Biomed Anal 2012; 71:45-53.
-
(2012)
J Pharm Biomed Anal
, vol.71
, pp. 45-53
-
-
Merola, G.1
Aturkib, Z.2
D'Oraziob, G.3
Gottardoc, R.4
Macchiaa, T.5
Tagliaroc, F.6
Fanalib, S.7
-
12
-
-
84860587471
-
LC-MS/MS method for the quantitation of metabolites of eight commonly-used synthetic cannabinoids in human urine--an Australian perspective
-
de Jager AD, Warner JV, Henman M, Ferguson W, Hall. LC-MS/MS method for the quantitation of metabolites of eight commonly-used synthetic cannabinoids in human urine--an Australian perspective. J Chromatogr B Analyt Technol Biomed Life Sci 2012; 897:22-31.
-
(2012)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.897
, pp. 22-31
-
-
de Jager, A.D.1
Warner, J.V.2
Henman, M.3
Ferguson, W.H.4
-
13
-
-
79955031826
-
Chromatography-mass spectrometry studies on the metabolism of synthetic cannabinoids JWH-018 and JWH-073, psychoactive components of smoking mixtures
-
Grigoryev A, Savchuk S, Melnik A, Moskaleva N, Dzhurko J, Ershov M, Nosyrev A, Vedenin A, Izotov B, Zabirova I, Rozhanets V. Chromatography-mass spectrometry studies on the metabolism of synthetic cannabinoids JWH-018 and JWH-073, psychoactive components of smoking mixtures. J Chromatogr B Analyt Technol Biomed Life Sci 2011; 879:1126-1136.
-
(2011)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.879
, pp. 1126-1136
-
-
Grigoryev, A.1
Savchuk, S.2
Melnik, A.3
Moskaleva, N.4
Dzhurko, J.5
Ershov, M.6
Nosyrev, A.7
Vedenin, A.8
Izotov, B.9
Zabirova, I.10
Rozhanets, V.11
-
14
-
-
77952291222
-
Chemical analysis of synthetic cannabinoids as designer drugs in herbal products
-
Uchiyama N, Kikura-Hanajiri R, Ogata J, Goda Y. Chemical analysis of synthetic cannabinoids as designer drugs in herbal products. Forensic Sci Int 2010; 198:31-38.
-
(2010)
Forensic Sci Int
, vol.198
, pp. 31-38
-
-
Uchiyama, N.1
Kikura-Hanajiri, R.2
Ogata, J.3
Goda, Y.4
-
15
-
-
84878084843
-
-
EMCDDA-Europol 2008 Annual Report on the Implementation of Council Decision 2005/387/JHA. Annex 2: New psychoactive substances reported to the EMCDDA and Europol for the first time in 2008 under the terms of Council Decision, 005/387/JHA,Accessed Feburary 21
-
EMCDDA-Europol 2008 Annual Report on the Implementation of Council Decision 2005/387/JHA. Annex 2: New psychoactive substances reported to the EMCDDA and Europol for the first time in 2008 under the terms of Council Decision, 005/387/JHA. http://www.emcdda.europa.eu/attachements.cfm/att_77263_EN_EMCDDA-Europol_Annual_Report_Art10_2008.pdf. Accessed Feburary 21, 2013.
-
(2013)
-
-
-
16
-
-
84878056500
-
-
EMCDDA, 2009 Annual report on the state of the drugs problem in Europe. European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 2009,Accessed February 19
-
EMCDDA, 2009 Annual report on the state of the drugs problem in Europe. European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 2009. http://www.emcdda.europa.eu/attachements.cfm/att_93236_EN_EMCDDA_AR2009_EN.pdf. Accessed February 19, 2013.
-
(2013)
-
-
-
17
-
-
84878053454
-
-
EMCDDA, 2010 Annual report on the state of the drugs problem in Europe. European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 2010,Accessed February 19
-
EMCDDA, 2010 Annual report on the state of the drugs problem in Europe. European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 2010. http://www.emcdda.europa.eu/ attachements.cfm/att_120104_EN_EMCDDA_AR2010_EN.pdf. Accessed February 19, 2013.
-
(2013)
-
-
-
18
-
-
84862657058
-
Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-[(5-fluoropentyl)-1Hindol- 3yl]-(4-methylnaphthalen-1-yl)methanone using GC-MS, NMR analysis and a flash chromatography system
-
Moosmann B, Kneisel S, Girreser U, Brecht V, Westphal F, Auwärter V. Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-[(5-fluoropentyl)-1Hindol- 3yl]-(4-methylnaphthalen-1-yl)methanone using GC-MS, NMR analysis and a flash chromatography system. Forensic Sci Int 2012; 220:17-22.
-
(2012)
Forensic Sci Int
, vol.220
, pp. 17-22
-
-
Moosmann, B.1
Kneisel, S.2
Girreser, U.3
Brecht, V.4
Westphal, F.5
Auwärter, V.6
-
19
-
-
70349117752
-
Withdrawal phenomena and dependence syndrome after the consumption of spice gold
-
Moosmann B, Kneisel S, Girreser U, Brecht V, Westphal F, Auwärter V. Withdrawal phenomena and dependence syndrome after the consumption of "spice gold". Dtsch Arztebl Int 2009; 106:464-467.
-
(2009)
Dtsch Arztebl Int
, vol.106
, pp. 464-467
-
-
Moosmann, B.1
Kneisel, S.2
Girreser, U.3
Brecht, V.4
Westphal, F.5
Auwärter, V.6
-
20
-
-
84855507862
-
Beyond THC: The new generation of cannabinoid designer drugs
-
Fattore L, Fratta W. Beyond THC: The new generation of cannabinoid designer drugs. Front Behav Neurosci 2011; 5:60-66.
-
(2011)
Front Behav Neurosci
, vol.5
, pp. 60-66
-
-
Fattore, L.1
Fratta, W.2
-
21
-
-
84878033423
-
-
AAPCC Issues Statement on the Synthetic Drug Abuse Prevention Act, American Association of Poison Control Centre, 2012,Accessed February 21
-
AAPCC Issues Statement on the Synthetic Drug Abuse Prevention Act. American Association of Poison Control Centre, 2012. http://www.aapcc.org/press/2/. Accessed February 21, 2013.
-
(2013)
-
-
-
22
-
-
84890798099
-
-
University of Michigan News Service: Ann Arbor, MI, 2012,Accessed Feburary 21
-
Johnston, LD, O'Malley PM, Bachman JG, Schulenberg JE. The rise in teen marijuana use stalls, synthetic marijuana use levels, and use of 'bath salts' is very low. University of Michigan News Service: Ann Arbor, MI, 2012. htttp://www.monitoringthefuture. org/pressreleases/12drugpr.pdf. Accessed Feburary 21, 2013.
-
(2013)
The rise in teen marijuana use stalls, synthetic marijuana use levels, and use of 'bath salts' is very low.
-
-
Johnston, L.D.1
O'Malley, P.M.2
Bachman, J.G.3
Schulenberg, J.E.4
-
24
-
-
80053020632
-
Synthetic cannabinoid use: A case series of adolescents
-
Castellanos D, Singh S, Thornton G, Avila M, Moreno A. Synthetic cannabinoid use: A case series of adolescents. J Adolesc Health 2011; 49:347-349.
-
(2011)
J Adolesc Health
, vol.49
, pp. 347-349
-
-
Castellanos, D.1
Singh, S.2
Thornton, G.3
Avila, M.4
Moreno, A.5
-
25
-
-
0032802188
-
Pharmacology of cannabinoid receptor ligands
-
Pertwee RG. Pharmacology of cannabinoid receptor ligands. Curr Med Chem 1999; 6:635-664.
-
(1999)
Curr Med Chem
, vol.6
, pp. 635-664
-
-
Pertwee, R.G.1
-
26
-
-
0032926695
-
The effects of cannabinoids on the brain
-
Ameri A. The effects of cannabinoids on the brain. Prog Neurobiol 1999; 58:315-348.
-
(1999)
Prog Neurobiol
, vol.58
, pp. 315-348
-
-
Ameri, A.1
-
27
-
-
0037207070
-
Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition
-
Hájos N, Freund TF. Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition. Chem Phys Lipids 2002; 121:73-82.
-
(2002)
Chem Phys Lipids
, vol.121
, pp. 73-82
-
-
Hájos, N.1
Freund, T.F.2
-
28
-
-
34748841430
-
The future of cannabinoids as analgesic agents: A pharmacologic, pharmacokinetic, and pharmacodynamic overview
-
McCarberg BH, Barkin RL. The future of cannabinoids as analgesic agents: A pharmacologic, pharmacokinetic, and pharmacodynamic overview. Am J Ther 2007; 14:475-483.
-
(2007)
Am J Ther
, vol.14
, pp. 475-483
-
-
McCarberg, B.H.1
Barkin, R.L.2
-
29
-
-
47349126394
-
Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists
-
Ashton JC, Wright JL, McPartland JM, Tyndall JDA. Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists. Curr Med Chem 2008; 15:1428-1443.
-
(2008)
Curr Med Chem
, vol.15
, pp. 1428-1443
-
-
Ashton, J.C.1
Wright, J.L.2
McPartland, J.M.3
Tyndall, J.D.A.4
-
30
-
-
78049346634
-
vitro phase I metabolism of the synthetic cannabimimetic JWH-018
-
Wintermeyer A, Möller I, Thevis M, et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018. Anal Bioanal Chem 2010; 398:2141-2153.
-
(2010)
Anal Bioanal Chem
, vol.398
, pp. 2141-2153
-
-
Wintermeyer, A.1
Möller, I.2
Thevis, M.3
-
31
-
-
77954175124
-
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression
-
Rieder SA, Chauhan A, Singh U, Nagarkatti M, Nagarkatti P. Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. Immunobiology 2010; 215:598-605.
-
(2010)
Immunobiology
, vol.215
, pp. 598-605
-
-
Rieder, S.A.1
Chauhan, A.2
Singh, U.3
Nagarkatti, M.4
Nagarkatti, P.5
-
32
-
-
70949091684
-
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
-
Qamri Z, Preet A, Nasser MW, Bass CE, Leone G, Barsky SH, Ganju RK. Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. Mol Cancer Ther 2009; 8:3117-3129.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3117-3129
-
-
Qamri, Z.1
Preet, A.2
Nasser, M.W.3
Bass, C.E.4
Leone, G.5
Barsky, S.H.6
Ganju, R.K.7
-
33
-
-
70249094588
-
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-methanandamide and JWH-015: Involvement of CB2
-
Olea-Herrero N, Vara D, Malagarie-Cazenave S, Díaz-Laviada I. Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-methanandamide and JWH-015: Involvement of CB2. Br J Cancer 2009; 101:940-950.
-
(2009)
Br J Cancer
, vol.101
, pp. 940-950
-
-
Olea-Herrero, N.1
Vara, D.2
Malagarie-Cazenave, S.3
Díaz-Laviada, I.4
-
34
-
-
26844504226
-
Identification and functional characterization of brainstem cannabinoid CB2 receptors
-
Van Sickle MD, Duncan M, Kingsley PJ, et al. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 2005; 310:329-332.
-
(2005)
Science
, vol.310
, pp. 329-332
-
-
Van Sickle, M.D.1
Duncan, M.2
Kingsley, P.J.3
-
35
-
-
56649122099
-
mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: Electrophysiological and FRET assay analysis
-
Hojo M, Sudo Y, Ando Y, Minami K, Takada M, Matsubara T, Kanaide M, Taniyama K, Sumikawa K, Uezono Y. mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: Electrophysiological and FRET assay analysis. J Pharmacol Sci 2008; 108:308-319.
-
(2008)
J Pharmacol Sci
, vol.108
, pp. 308-319
-
-
Hojo, M.1
Sudo, Y.2
Ando, Y.3
Minami, K.4
Takada, M.5
Matsubara, T.6
Kanaide, M.7
Taniyama, K.8
Sumikawa, K.9
Uezono, Y.10
-
36
-
-
77950803144
-
Opioids and cannabinoids interactions: Involvement in pain management
-
Desroches J, Beaulieu P. Opioids and cannabinoids interactions: Involvement in pain management. Curr Drug Targets 2010; 11:462-473.
-
(2010)
Curr Drug Targets
, vol.11
, pp. 462-473
-
-
Desroches, J.1
Beaulieu, P.2
-
37
-
-
0012872233
-
Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding
-
Aung MM, Griffin G, Huffman JW, Wu M-J, Keel C, Yang B, Showalter VM, Abood ME, Martin BR. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend 2000; 60:133-140.
-
(2000)
Drug Alcohol Depend
, vol.60
, pp. 133-140
-
-
Aung, M.M.1
Griffin, G.2
Huffman, J.W.3
Wu, M.-J.4
Keel, C.5
Yang, B.6
Showalter, V.M.7
Abood, M.E.8
Martin, B.R.9
-
38
-
-
23644461192
-
1-Pentyl-3- phenylacetylindoles, a new class of cannabimimetic indoles
-
Huffman JW, Szklennik PV, Almond A, Bushell K, Selley DE, He H, Cassidy MP, Wiley JL, Martin BR. 1-Pentyl-3- phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett 2005; 15:4110-4113.
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 4110-4113
-
-
Huffman, J.W.1
Szklennik, P.V.2
Almond, A.3
Bushell, K.4
Selley, D.E.5
He, H.6
Cassidy, M.P.7
Wiley, J.L.8
Martin, B.R.9
-
39
-
-
21044448570
-
Recent developments in the medicinal chemistry of cannabinomimetic indoles, pyrroles and indenes
-
Huffman JW, Padgett LW. Recent developments in the medicinal chemistry of cannabinomimetic indoles, pyrroles and indenes. Curr Med Chem 2005; 12:1395-1411.
-
(2005)
Curr Med Chem
, vol.12
, pp. 1395-1411
-
-
Huffman, J.W.1
Padgett, L.W.2
-
40
-
-
0037248374
-
3-Indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor
-
Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR. 3-Indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor. Bioorg Med Chem 2003; 11:539-549.
-
(2003)
Bioorg Med Chem
, vol.11
, pp. 539-549
-
-
Huffman, J.W.1
Mabon, R.2
Wu, M.J.3
Lu, J.4
Hart, R.5
Hurst, D.P.6
Reggio, P.H.7
Wiley, J.L.8
Martin, B.R.9
-
41
-
-
77955897603
-
Use of high resolution accurate mass spectrometry to detect reported and previously unreported cannabinomimetics in "herbal high" products
-
Hudson S, Ramsey J, King L, Timbers S, Maynard S, Dargan PI, Wood DM. Use of high resolution accurate mass spectrometry to detect reported and previously unreported cannabinomimetics in "herbal high" products. J Anal Toxicol 2010; 34:252-260.
-
(2010)
J Anal Toxicol
, vol.34
, pp. 252-260
-
-
Hudson, S.1
Ramsey, J.2
King, L.3
Timbers, S.4
Maynard, S.5
Dargan, P.I.6
Wood, D.M.7
-
42
-
-
84155164719
-
A survey study to characterize use of Spice products (synthetic cannabinoids)
-
Vandrey R, Dunn KE, Fry JA, Girling ER. A survey study to characterize use of Spice products (synthetic cannabinoids). Drug Alcohol Depend 2012; 120:238-241.
-
(2012)
Drug Alcohol Depend
, vol.120
, pp. 238-241
-
-
Vandrey, R.1
Dunn, K.E.2
Fry, J.A.3
Girling, E.R.4
-
43
-
-
84878056890
-
-
UNODC, Synthetic cannabinoids in herbal products, United Nations Office on Drugs and Crime, 2011,Last accessed February 19
-
UNODC, Synthetic cannabinoids in herbal products. United Nations Office on Drugs and Crime, 2011. http://www.unodc.org/documents/scientific/Synthetic_Cannabinoids.pdf. Last accessed February 19, 2013.
-
(2013)
-
-
-
44
-
-
79959567447
-
A preliminary investigation on the distribution of cannabinoids in man
-
Gronewold A, Skopp G. A preliminary investigation on the distribution of cannabinoids in man. Forensic Sci Int 2011; 210:7- 11.
-
(2011)
Forensic Sci Int
, vol.210
, pp. 7-11
-
-
Gronewold, A.1
Skopp, G.2
-
45
-
-
80053166693
-
Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases
-
Chimalakonda KC, Bratton SM, Le VH, Yiew KH, Dineva A, Moran CL, James LP, Moran JH, Radominska-Pandya A. Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases. Drug Metab Dispos 2011; 39:1967-1976.
-
(2011)
Drug Metab Dispos
, vol.39
, pp. 1967-1976
-
-
Chimalakonda, K.C.1
Bratton, S.M.2
Le, V.H.3
Yiew, K.H.4
Dineva, A.5
Moran, C.L.6
James, L.P.7
Moran, J.H.8
Radominska-Pandya, A.9
-
46
-
-
84878101477
-
-
EMCDDA, Understanding the 'Spice' phenomenon, European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 2009,Last accessed February 19
-
EMCDDA, Understanding the 'Spice' phenomenon. European Monitoring Centre for Drugs and Drug Addiction, Lisbon, 2009. http://www.emcdda.europa.eu/attachements.cfm/att_80086_EN_Spice%20Thematic%20paper%20%E2%80%94%20final%20version.pdf. Last accessed February 19, 2013.
-
(2013)
-
-
-
47
-
-
84859853678
-
A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors
-
Seely KA, Brents LK, Radominska-Pandya A, Endres GW, Keyes GS, Moran JH, Prather PL. A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors. Curr Res Toxicol 2012; 4:825-827.
-
(2012)
Curr Res Toxicol
, vol.4
, pp. 825-827
-
-
Seely, K.A.1
Brents, L.K.2
Radominska-Pandya, A.3
Endres, G.W.4
Keyes, G.S.5
Moran, J.H.6
Prather, P.L.7
-
48
-
-
84857372061
-
Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity
-
Brents LK, Gallus-Zawada A, Radominska-Pandya A, Vasiljevik T, Prisinzano TE, Fantegrossi WE, Moran JH, Prather PL. Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. Biochem Pharmacol 2012; 83:952-961.
-
(2012)
Biochem Pharmacol
, vol.83
, pp. 952-961
-
-
Brents, L.K.1
Gallus-Zawada, A.2
Radominska-Pandya, A.3
Vasiljevik, T.4
Prisinzano, T.E.5
Fantegrossi, W.E.6
Moran, J.H.7
Prather, P.L.8
-
49
-
-
84866989897
-
Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids
-
Seely KA, Lapoint J, Moran JH, Fattore L. Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids. Prog Neuropsychopharmacol Biol Psychiatry 2012; 39:234-243.
-
(2012)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.39
, pp. 234-243
-
-
Seely, K.A.1
Lapoint, J.2
Moran, J.H.3
Fattore, L.4
-
50
-
-
80052277722
-
Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB1 and CB2 receptors
-
Uchiyama N, Kikura-Hanajiri R, Goda Y. Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB1 and CB2 receptors. Chem Pharm Bull 2011; 59:1203-1205.
-
(2011)
Chem Pharm Bull
, vol.59
, pp. 1203-1205
-
-
Uchiyama, N.1
Kikura-Hanajiri, R.2
Goda, Y.3
-
51
-
-
33744827120
-
Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes
-
Ghosh S, Preet A, Groopman JE, Ganju RK. Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes. Mol Immunol 2006; 43:2169-2179.
-
(2006)
Mol Immunol
, vol.43
, pp. 2169-2179
-
-
Ghosh, S.1
Preet, A.2
Groopman, J.E.3
Ganju, R.K.4
-
52
-
-
33846828655
-
CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells: Potential role for CB2-selective ligands as immunosuppressive agents
-
Lombard C, Nagarkatti M, Nagarkatti P. CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells: Potential role for CB2-selective ligands as immunosuppressive agents. Clin Immunol 2007; 122:259-270.
-
(2007)
Clin Immunol
, vol.122
, pp. 259-270
-
-
Lombard, C.1
Nagarkatti, M.2
Nagarkatti, P.3
-
53
-
-
33749544716
-
Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain
-
Onaivi ES, Ishiguro H, Gong JP, Patel S, Perchuk A, Meozzi PA, et al. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Ann N Y Acad Sci 2006; 1074:514-536.
-
(2006)
Ann N Y Acad Sci
, vol.1074
, pp. 514-536
-
-
Onaivi, E.S.1
Ishiguro, H.2
Gong, J.P.3
Patel, S.4
Perchuk, A.5
Meozzi, P.A.6
-
54
-
-
33845959991
-
Cannabinoid CB2 receptor: A new target for controlling neural cell survival?
-
Fernández-Ruiz J, Romero J, Velasco G, Tolón RM, Ramos JA, Guzmán M. Cannabinoid CB2 receptor: A new target for controlling neural cell survival? Trends Pharmacol Sci 2007; 28:39-45.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 39-45
-
-
Fernández-Ruiz, J.1
Romero, J.2
Velasco, G.3
Tolón, R.M.4
Ramos, J.A.5
Guzmán, M.6
-
55
-
-
45749134610
-
Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: From mice to human subjects
-
Onaivi ES, Ishiguro H, Gong JP, Patel S, Meozzi PA, Myers L, Perchuk A, Mora Z, Tagliaferro PA, Gardner E, Brusco A, Akinshola BE, Hope B, Lujilde J, Inada T, Iwasaki S, Macharia D, Teasenfitz L, Arinami T, Uhl GR. Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: From mice to human subjects. PLoS One 2008; 3:1640.
-
(2008)
PLoS One
, vol.3
, pp. 1640
-
-
Onaivi, E.S.1
Ishiguro, H.2
Gong, J.P.3
Patel, S.4
Meozzi, P.A.5
Myers, L.6
Perchuk, A.7
Mora, Z.8
Tagliaferro, P.A.9
Gardner, E.10
Brusco, A.11
Akinshola, B.E.12
Hope, B.13
Lujilde, J.14
Inada, T.15
Iwasaki, S.16
Macharia, D.17
Teasenfitz, L.18
Arinami, T.19
Uhl, G.R.20
more..
-
56
-
-
53549086169
-
Functional expression of brain neuronal CB2 cannabinoid receptors are involved in the effects of drugs of abuse and in depression
-
Onaivi ES, Ishiguro H, Gong JP, Patel S, Meozzi PA, Myers L, Perchuk A, Mora Z, Tagliaferro PA, Gardner E, Brusco A, Akinshola BE, Liu QR, Chirwa SS, Hope B, Lujilde J, Inada T, Iwasaki S, Macharia D, Teasenfitz L, Arinami T, Uhl GR. Functional expression of brain neuronal CB2 cannabinoid receptors are involved in the effects of drugs of abuse and in depression. Ann N Y Acad Sci 2008; 1139:434-449.
-
(2008)
Ann N Y Acad Sci
, vol.1139
, pp. 434-449
-
-
Onaivi, E.S.1
Ishiguro, H.2
Gong, J.P.3
Patel, S.4
Meozzi, P.A.5
Myers, L.6
Perchuk, A.7
Mora, Z.8
Tagliaferro, P.A.9
Gardner, E.10
Brusco, A.11
Akinshola, B.E.12
Liu, Q.R.13
Chirwa, S.S.14
Hope, B.15
Lujilde, J.16
Inada, T.17
Iwasaki, S.18
Macharia, D.19
Teasenfitz, L.20
Arinami, T.21
Uhl, G.R.22
more..
-
57
-
-
80052213796
-
Brain cannabinoid CB2 receptors modulate cocaine's actions in mice
-
Xi ZX, Peng XQ, Li X, Song R, Zhang HY, Liu QR, Yang HJ, Bi GH, Li J, Gardner EL. Brain cannabinoid CB2 receptors modulate cocaine's actions in mice. Nat Neurosci 2011; 14:1160-1166.
-
(2011)
Nat Neurosci
, vol.14
, pp. 1160-1166
-
-
Xi, Z.X.1
Peng, X.Q.2
Li, X.3
Song, R.4
Zhang, H.Y.5
Liu, Q.R.6
Yang, H.J.7
Bi, G.H.8
Li, J.9
Gardner, E.L.10
-
58
-
-
0036019422
-
Anandamide receptors
-
Di Marzo V, De Petrocellis L, Fezza F, Ligresti A, Bisogno T. Anandamide receptors. Prostaglandins Leukot Essent Fatty Acids 2002; 66:377-391.
-
(2002)
Prostaglandins Leukot Essent Fatty Acids
, vol.66
, pp. 377-391
-
-
Di Marzo, V.1
De Petrocellis, L.2
Fezza, F.3
Ligresti, A.4
Bisogno, T.5
-
59
-
-
73549098434
-
Ligand- and heterodimerdirected signaling of the CB(1) cannabinoid receptor
-
Hudson BD, Hébert TE, Kelly ME. Ligand- and heterodimerdirected signaling of the CB(1) cannabinoid receptor. Mol Pharmacol 2010; 77:1-9.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 1-9
-
-
Hudson, B.D.1
Hébert, T.E.2
Kelly, M.E.3
-
60
-
-
36448968578
-
Allosteric modulation of heterodimeric G-protein-coupled receptors
-
Milligan G, Smith NJ. Allosteric modulation of heterodimeric G-protein-coupled receptors. Trends Pharmacol Sci 2007; 28:615-620.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 615-620
-
-
Milligan, G.1
Smith, N.J.2
-
61
-
-
84863823864
-
Novel psychoactive substances: How to understand the acute toxicity associated with the use of these substances
-
Wood DM, Dargan PI. Novel psychoactive substances: How to understand the acute toxicity associated with the use of these substances. Ther Drug Monit 2012; 34:363-367.
-
(2012)
Ther Drug Monit
, vol.34
, pp. 363-367
-
-
Wood, D.M.1
Dargan, P.I.2
-
62
-
-
79954444738
-
Comparison of "herbal highs" composition
-
Zuba D, Byrska B, Maciow M. Comparison of "herbal highs" composition. Anal Bioanal Chem 2011; 400:119-126.
-
(2011)
Anal Bioanal Chem
, vol.400
, pp. 119-126
-
-
Zuba, D.1
Byrska, B.2
Maciow, M.3
-
63
-
-
78650752280
-
Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds
-
Dresen S, Ferreirós N, Pütz M, Westphal F, Zimmermann R, Auwärter V. Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds. J Mass Spectrom 2010; 45:1186-1194.
-
(2010)
J Mass Spectrom
, vol.45
, pp. 1186-1194
-
-
Dresen, S.1
Ferreirós, N.2
Pütz, M.3
Westphal, F.4
Zimmermann, R.5
Auwärter, V.6
-
65
-
-
78751564069
-
Intoxication from smoking "Spice"
-
Simmons JR, Skinner CG, Williams J, Kang CS, Schwartz MD, Wills BK. Intoxication from smoking "Spice". Ann Emerg Med 2011; 57:187-188.
-
(2011)
Ann Emerg Med
, vol.57
, pp. 187-188
-
-
Simmons, J.R.1
Skinner, C.G.2
Williams, J.3
Kang, C.S.4
Schwartz, M.D.5
Wills, B.K.6
-
66
-
-
77951979345
-
The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes
-
Müller H, Sperling W, Köhrmann M, Huttner HB, Kornhuber J, Maler JM. The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes. Schizophr Res 2010; 118:309-310.
-
(2010)
Schizophr Res
, vol.118
, pp. 309-310
-
-
Müller, H.1
Sperling, W.2
Köhrmann, M.3
Huttner, H.B.4
Kornhuber, J.5
Maler, J.M.6
-
67
-
-
77956782377
-
Warning: Legal synthetic cannabinoid-receptor agonists such as JWH018 may precipitate psychosis in vulnerable individuals
-
Every-Palmer S. Warning: Legal synthetic cannabinoid-receptor agonists such as JWH018 may precipitate psychosis in vulnerable individuals. Addiction 2010; 105:1859-1860.
-
(2010)
Addiction
, vol.105
, pp. 1859-1860
-
-
Every-Palmer, S.1
-
68
-
-
79952814790
-
Spice girls: Synthetic cannabinoid intoxication
-
Schneir AB, Cullen J, Ly BT. "Spice" girls: Synthetic cannabinoid intoxication. J Emerg Med 2011; 40:296-299.
-
(2011)
J Emerg Med
, vol.40
, pp. 296-299
-
-
Schneir, A.B.1
Cullen, J.2
Ly, B.T.3
-
69
-
-
77956872578
-
Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl) methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry
-
Teske J, Weller JP, Fieguth A, Rothämel T, Schulz Y, Tröger HD. Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl) methanone (JWH- 018) in human serum by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2010; 878:2659-2663.
-
(2010)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.878
, pp. 2659-2663
-
-
Teske, J.1
Weller, J.P.2
Fieguth, A.3
Rothämel, T.4
Schulz, Y.5
Tröger, H.D.6
-
70
-
-
84873157996
-
Synthetic cannabinoid intoxication: A case series and review
-
Harris CR, Brown A. Synthetic cannabinoid intoxication: A case series and review. J Emerg Med 2013; 44:360-366.
-
(2013)
J Emerg Med
, vol.44
, pp. 360-366
-
-
Harris, C.R.1
Brown, A.2
-
71
-
-
67651146922
-
Chronic toxicology of cannabis
-
Reece AS. Chronic toxicology of cannabis. Clin Toxicol 2009; 47:517-524.
-
(2009)
Clin Toxicol
, vol.47
, pp. 517-524
-
-
Reece, A.S.1
-
72
-
-
84863009341
-
Synthetic legal intoxicating drugs: The emerging 'incense' and 'bath salt' phenomenon
-
Jerry J, Collins G, Streem D. Synthetic legal intoxicating drugs: The emerging 'incense' and 'bath salt' phenomenon. Cleve Clin J Med 2012; 79:258-264.
-
(2012)
Cleve Clin J Med
, vol.79
, pp. 258-264
-
-
Jerry, J.1
Collins, G.2
Streem, D.3
-
73
-
-
83255192504
-
Myocardial infarction associated with use of the synthetic cannabinoid K2
-
Mir A, Obafemi A, Young A, Kane C. Myocardial infarction associated with use of the synthetic cannabinoid K2. Pediatrics 2011; 128:1622-1627.
-
(2011)
Pediatrics
, vol.128
, pp. 1622-1627
-
-
Mir, A.1
Obafemi, A.2
Young, A.3
Kane, C.4
-
74
-
-
84857759598
-
Here today, gone tomorrow and back again? A review of herbal marijuana alternatives (K2, Spice), synthetic cathinones bath salts), Kratom, Salvia divinorum, methoxetamine, and piperazines
-
Rosenbaum CD, Carreiro SP, Babu KM. Here today, gone tomorrow and back again? A review of herbal marijuana alternatives (K2, Spice), synthetic cathinones bath salts), Kratom, Salvia divinorum, methoxetamine, and piperazines. J Med Toxicol 2012; 8:15-32.
-
(2012)
J Med Toxicol
, vol.8
, pp. 15-32
-
-
Rosenbaum, C.D.1
Carreiro, S.P.2
Babu, K.M.3
-
75
-
-
77951853072
-
Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults
-
McGrath J, Welham J, Scott J, Varghese D, Degenhardt L, Hayatbakhsh MR, Alati R, Williams GM, Bor W, Najman JM. Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults. Arch Gen Psychiatry 2010; 67:440-447.
-
(2010)
Arch Gen Psychiatry
, vol.67
, pp. 440-447
-
-
McGrath, J.1
Welham, J.2
Scott, J.3
Varghese, D.4
Degenhardt, L.5
Hayatbakhsh, M.R.6
Alati, R.7
Williams, G.M.8
Bor, W.9
Najman, J.M.10
-
76
-
-
0037164390
-
Cannabis use in adolescence and risk for adult psychosis: Longitudinal prospective study
-
Arseneault L, Cannon M, Poulton R, Murray R, Caspi A, Moffitt TE. Cannabis use in adolescence and risk for adult psychosis: Longitudinal prospective study. BMJ 2002; 325:1212-1213.
-
(2002)
BMJ
, vol.325
, pp. 1212-1213
-
-
Arseneault, L.1
Cannon, M.2
Poulton, R.3
Murray, R.4
Caspi, A.5
Moffitt, T.E.6
-
78
-
-
79960313022
-
Synthetic cannabinoid JWH-018 and psychosis: An explorative study
-
Every-Palmer S. Synthetic cannabinoid JWH-018 and psychosis: An explorative study. Drug Alcohol Depend 2011; 117:152-157.
-
(2011)
Drug Alcohol Depend
, vol.117
, pp. 152-157
-
-
Every-Palmer, S.1
-
79
-
-
80054812520
-
Psychosis associated with synthetic cannabinoid agonists: A case series
-
Hurst D, Loeffler G, McLay R. Psychosis associated with synthetic cannabinoid agonists: A case series. Am J Psychiatry 2011; 168:1119.
-
(2011)
Am J Psychiatry
, vol.168
, pp. 1119
-
-
Hurst, D.1
Loeffler, G.2
McLay, R.3
-
80
-
-
67349149647
-
Toxicity and metabolism of methylnaphthalenes: Comparison with naphthalene and 1-nitronaphthalene
-
Lin CY, Wheelock AM, Morin D, Baldwin RM, Lee MG, Taff A, Plopper C, Buckpitt A, Rohde A. Toxicity and metabolism of methylnaphthalenes: Comparison with naphthalene and 1-nitronaphthalene. Toxicology 2009; 260:16-27.
-
(2009)
Toxicology
, vol.260
, pp. 16-27
-
-
Lin, C.Y.1
Wheelock, A.M.2
Morin, D.3
Baldwin, R.M.4
Lee, M.G.5
Taff, A.6
Plopper, C.7
Buckpitt, A.8
Rohde, A.9
-
81
-
-
84881555267
-
Identification of two cannabimimetic compounds WIN48098 and AM679 in illegal products
-
press
-
Gregori A, Damiano F, Bonavia M, Mileo V, Varani F, Monfreda M. Identification of two cannabimimetic compounds WIN48098 and AM679 in illegal products. Science and Justice 2012 (inpress).
-
(2012)
Science and Justice
-
-
Gregori, A.1
Damiano, F.2
Bonavia, M.3
Mileo, V.4
Varani, F.5
Monfreda, M.6
-
82
-
-
79951683329
-
Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantitation of synthetic cannabinoids of the aminoalkylindole type and methanandamide in serum and its application to forensic samples
-
Dresen S, Kneisel S, Weinmann W, Zimmermann R, Auwärter V. Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantitation of synthetic cannabinoids of the aminoalkylindole type and methanandamide in serum and its application to forensic samples. J Mass Spectrom 2011; 46:163-171.
-
(2011)
J Mass Spectrom
, vol.46
, pp. 163-171
-
-
Dresen, S.1
Kneisel, S.2
Weinmann, W.3
Zimmermann, R.4
Auwärter, V.5
-
84
-
-
84856349177
-
Identification of the major urinary metabolites in man of seven synthetic cannabinoids of the aminoalkylindole type present as adulterants in 'herbal mixtures' using LC-MS/MS techniques
-
Hutter M, Broecker S, Kneise Sl, Auwärter V. Identification of the major urinary metabolites in man of seven synthetic cannabinoids of the aminoalkylindole type present as adulterants in 'herbal mixtures' using LC-MS/MS techniques. J Mass Spectrom 2012; 47:54-65.
-
(2012)
J Mass Spectrom
, vol.47
, pp. 54-65
-
-
Hutter, M.1
Broecker, S.2
Kneise, S.L.3
Auwärter, V.4
-
86
-
-
80053415706
-
Screening for the synthetic cannabinoid JWH-018 and its major metabolites in human doping controls
-
Möller I, Wintermeyer A, Bender K, et al. Screening for the synthetic cannabinoid JWH-018 and its major metabolites in human doping controls. Drug Test Anal 2011; 3:609-620.
-
(2011)
Drug Test Anal
, vol.3
, pp. 609-620
-
-
Möller, I.1
Wintermeyer, A.2
Bender, K.3
-
87
-
-
84878065118
-
-
2011 National report (2010 data) to the EMCDDA. "TURKEY" New Development, Trends and in-depth information on selected issues. Reitox National Focal Point, 2012,Last accessed Feburary 18
-
2011 National report (2010 data) to the EMCDDA. "TURKEY" New Development, Trends and in-depth information on selected issues. Reitox National Focal Point, 2012. http://www.emcdda. europa.eu/attachements.cfm/att_191577_EN_Turkey_2011.pdf. Last accessed Feburary 18, 2013.
-
(2013)
-
-
-
88
-
-
77951989152
-
How globalization and market innovation challenge how we think about and respond to drug use: 'Spice' a case study
-
Griffiths P, Sedefov R, Gallegos A, Lopez D. How globalization and market innovation challenge how we think about and respond to drug use: 'Spice' a case study. Addiction 2010; 105:951-953.
-
(2010)
Addiction
, vol.105
, pp. 951-953
-
-
Griffiths, P.1
Sedefov, R.2
Gallegos, A.3
Lopez, D.4
-
89
-
-
79960003774
-
Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity
-
Brents LK, Reichard EE, Zimmerman SM, Moran JH, Fantegrossi WE, Prather PL. Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity. PLoS One 2011; 6:21917.
-
(2011)
PLoS One
, vol.6
, pp. 21917
-
-
Brents, L.K.1
Reichard, E.E.2
Zimmerman, S.M.3
Moran, J.H.4
Fantegrossi, W.E.5
Prather, P.L.6
|