Conjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases

Drug Metabolism and Disposition

Volumn 39, Issue 10, 2011, Pages 1967-1976

  Chimalakonda, Krishna C ^a,d   Bratton, Stacie M ^a   Le, Vi Huyen ^d   Yiew, Kan Hui ^a   Dineva, Anna ^a   Moran, Cindy L ^b   James, Laura P ^c   Moran, Jeffery H ^a,d   Radominska Pandya, Anna ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b Arkansas State Crime Laboratory   (United States)

^c ARKANSAS CHILDREN S HOSPITAL   (United States)

^d ARKANSAS DEPARTMENT OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(1 BUTYL 1H INDOL 3 YL) 1 NAPHTHALENYLMETHANONE; 1 NAPHTHALENYL 1(1 PENTYL 1H INDOL 3 YL)METHANONE; 3 (1 NAPHTHOYL) 1 PENTYLINDOLE; CANNABINOID DERIVATIVE; DRUG METABOLITE; GLUCURONOSYLTRANSFERASE; JWH 073; RECOMBINANT ENZYME; RECOMBINANT GLUCURONOSYLTRANSFERASE; RECOMBINANT GLUCURONOSYLTRANSFERASE 1A1; RECOMBINANT GLUCURONOSYLTRANSFERASE 1A10; RECOMBINANT GLUCURONOSYLTRANSFERASE 1A3; RECOMBINANT GLUCURONOSYLTRANSFERASE 1A9; RECOMBINANT GLUCURONOSYLTRANSFERASE 2B7; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG CONJUGATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTESTINE MICROSOME; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MICROSOME; NONHUMAN; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

CANNABINOIDS; CHROMATOGRAPHY, LIQUID; GLUCURONIC ACID; GLUCURONOSYLTRANSFERASE; HUMANS; HYDROXYLATION; INDOLES; INTESTINES; KINETICS; MASS SPECTROMETRY; METABOLIC DETOXICATION, PHASE II; MICROSOMES; MICROSOMES, LIVER; NAPHTHALENES; PROTEIN ISOFORMS; RECOMBINANT PROTEINS;

CANNABIS SATIVA; SYNCOPE;

EID: 80053166693     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.040709     Document Type: Article

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