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Volumn 71, Issue , 2012, Pages 45-53

Analysis of synthetic cannabinoids in herbal blends by means of nano-liquid chromatography

Author keywords

Herbal blends; Mass spectrometry; Nano liquid chromatography; Synthetic cannabinoids

Indexed keywords

(1 (2 MORPHOLIN 4 YLETHYL)INDOL 3 YL)NAPHTHALEN 1 YLMETHANONE; (4 METHYL 1 NAPHTHYL)(1 PENTYLINDOL 3 YL)METHANONE; 1 [(5 FLUOROPENTYL) 1H INDOL 3 YL](2 IODOPHENYL)METHANONE; 2 (2 CHLOROPHENYL) 1 (1 PENTYLINDOL 3 YL)ETHANONE; 2 (2 METHOXYPHENYL) 1 (1 PENTYLINDOL 3 YL)ETHANONE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 3 (1 NAPHTHOYL) 1 PENTYLINDOLE; 4 METHOXYNAPHTHALEN 1 YL(1 PENTYLINDOL 3 YL)METHANONE; AM 694; CANNABINOID; DRONABINOL; FORMIC ACID; JWH 019; JWH 073; JWH 081; JWH 122; JWH 200; JWH 203; JWH 250; NAPHTHALEN 1 YL(1 BUTYLINDOL 3 YL)METHANONE; NAPHTHALEN 1 YL(1 HEXYLINDOL 3 YL)METHANONE; NAPHTHALEN 1 YL(1 PENTYLINDOL 3 YL)METHANONE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

EID: 84866760136     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.08.008     Document Type: Article
Times cited : (43)

References (44)
  • 1
    • 77954954841 scopus 로고    scopus 로고
    • Spice drugs as a new trend: mode of action, identification and legislation
    • Vardakou I., Pistos C., Spiliopoulou Ch. Spice drugs as a new trend: mode of action, identification and legislation. Toxicol. Lett. 2010, 197:157-162.
    • (2010) Toxicol. Lett. , vol.197 , pp. 157-162
    • Vardakou, I.1    Pistos, C.2    Spiliopoulou, C.3
  • 4
    • 77953912640 scopus 로고    scopus 로고
    • Cannabimimetic indoles, pyrroles, and indenes: structure-activity relationships and receptor interactions
    • Humana Press, New York, P.H. Reggio (Ed.)
    • Huffman J.W. Cannabimimetic indoles, pyrroles, and indenes: structure-activity relationships and receptor interactions. The Cannabinoid Receptors 2009, 49-94. Humana Press, New York. P.H. Reggio (Ed.).
    • (2009) The Cannabinoid Receptors , pp. 49-94
    • Huffman, J.W.1
  • 6
    • 77956782377 scopus 로고    scopus 로고
    • Warning: legal synthetic cannabinoid-receptor agonists such as JWH-018 may precipitate psychosis in vulnerable individuals
    • Every-Palmer S. Warning: legal synthetic cannabinoid-receptor agonists such as JWH-018 may precipitate psychosis in vulnerable individuals. Addiction 2010, 105:1859-1860.
    • (2010) Addiction , vol.105 , pp. 1859-1860
    • Every-Palmer, S.1
  • 7
    • 77951979345 scopus 로고    scopus 로고
    • The synthetic cannabinoid spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes
    • Müller H., Sperling W., Khrmann M., Huttner H.B., Kornhuber J., Maler J.M. The synthetic cannabinoid spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes. Schizophr. Res. 2010, 118:309-310.
    • (2010) Schizophr. Res. , vol.118 , pp. 309-310
    • Müller, H.1    Sperling, W.2    Khrmann, M.3    Huttner, H.B.4    Kornhuber, J.5    Maler, J.M.6
  • 8
    • 79952814790 scopus 로고    scopus 로고
    • " Spice girls" : synthetic cannabinoid intoxication
    • Schneir A.B., Cullen J., Ly B.T. " Spice girls" : synthetic cannabinoid intoxication. J. Emerg. Med. 2011, 40:296-299.
    • (2011) J. Emerg. Med. , vol.40 , pp. 296-299
    • Schneir, A.B.1    Cullen, J.2    Ly, B.T.3
  • 10
    • 79960313022 scopus 로고    scopus 로고
    • Synthetic cannabinoid JWH-018 and psychosis: an explorative study
    • Every-Palmer S. Synthetic cannabinoid JWH-018 and psychosis: an explorative study. Drug Alcohol Depend. 2011, 117:152-157.
    • (2011) Drug Alcohol Depend. , vol.117 , pp. 152-157
    • Every-Palmer, S.1
  • 11
    • 80052884588 scopus 로고    scopus 로고
    • Psychiatric sequelae of spice, k2, and synthetic cannabinoid receptor agonists
    • Benford D.M., Caplan J.P. Psychiatric sequelae of spice, k2, and synthetic cannabinoid receptor agonists. Psychosomatics 2011, 52:295.
    • (2011) Psychosomatics , vol.52 , pp. 295
    • Benford, D.M.1    Caplan, J.P.2
  • 13
    • 77953915638 scopus 로고    scopus 로고
    • Detection of JWH-018 metabolites in smoking mixture post-administration urine
    • Sobolevsky T., Prasolov I., Rodchenkov G. Detection of JWH-018 metabolites in smoking mixture post-administration urine. Forensic Sci. Int. 2010, 200:141-147.
    • (2010) Forensic Sci. Int. , vol.200 , pp. 141-147
    • Sobolevsky, T.1    Prasolov, I.2    Rodchenkov, G.3
  • 14
    • 80052616750 scopus 로고    scopus 로고
    • Liquid chromatography-tandem mass spectrometry analysis of urine specimens for K28 (JWH-018)
    • ElSohly M.A., Gul W., Elsohly K.M., Murphy T.P., Madgula V.L., Khan S.I. Liquid chromatography-tandem mass spectrometry analysis of urine specimens for K28 (JWH-018). J. Anal. Toxicol. 2011, 35:487-495.
    • (2011) J. Anal. Toxicol. , vol.35 , pp. 487-495
    • ElSohly, M.A.1    Gul, W.2    Elsohly, K.M.3    Murphy, T.P.4    Madgula, V.L.5    Khan, S.I.6
  • 15
    • 79960562678 scopus 로고    scopus 로고
    • Structure characterisation of urinary metabolites of the cannabimimetic JWH-018 using chemically synthesised reference material for the support of LC-MS/MS-based drug testing
    • Beuck S., Möller I., Thomas A., Klose A., Schlörer N., Schänzer W., Thevis M. Structure characterisation of urinary metabolites of the cannabimimetic JWH-018 using chemically synthesised reference material for the support of LC-MS/MS-based drug testing. Anal. Bioanal. Chem. 2011, 401:493-505.
    • (2011) Anal. Bioanal. Chem. , vol.401 , pp. 493-505
    • Beuck, S.1    Möller, I.2    Thomas, A.3    Klose, A.4    Schlörer, N.5    Schänzer, W.6    Thevis, M.7
  • 16
    • 77956872578 scopus 로고    scopus 로고
    • Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalene-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry
    • Teske J., Weller J.P., Fieguth A., Rothämel T., Schulz Y., Tröger H.D. Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalene-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 2010, 878:2659-2663.
    • (2010) J. Chromatogr. B , vol.878 , pp. 2659-2663
    • Teske, J.1    Weller, J.P.2    Fieguth, A.3    Rothämel, T.4    Schulz, Y.5    Tröger, H.D.6
  • 18
    • 84856349177 scopus 로고    scopus 로고
    • Identification of the major urinary metabolites in man of seven synthetic cannabinoids of the aminoalkyindole type present as adulterants in 'herbal mixtures' using LC-MS/MS techniques
    • Hutter M., Broecker S., Kneisel S., Auwärter V. Identification of the major urinary metabolites in man of seven synthetic cannabinoids of the aminoalkyindole type present as adulterants in 'herbal mixtures' using LC-MS/MS techniques. J. Mass Spectrom. 2012, 47:54-65.
    • (2012) J. Mass Spectrom. , vol.47 , pp. 54-65
    • Hutter, M.1    Broecker, S.2    Kneisel, S.3    Auwärter, V.4
  • 19
    • 79951683329 scopus 로고    scopus 로고
    • Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantitation of synthetic cannabinoids of the aminoalkylindole type and methanandamide in serum and its application to forensic samples
    • Dresen S., Kneisel S., Weinmann W., Zimmermann R., Auwärter V. Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantitation of synthetic cannabinoids of the aminoalkylindole type and methanandamide in serum and its application to forensic samples. J. Mass Spectrom. 2011, 46:163-171.
    • (2011) J. Mass Spectrom. , vol.46 , pp. 163-171
    • Dresen, S.1    Kneisel, S.2    Weinmann, W.3    Zimmermann, R.4    Auwärter, V.5
  • 21
    • 78650752280 scopus 로고    scopus 로고
    • Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds
    • Dresen S., Ferreirós N., Pütz M., Westphal F., Zimmermann R., Auwärter V. Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds. J. Mass Spectrom. 2010, 45:1186-1194.
    • (2010) J. Mass Spectrom. , vol.45 , pp. 1186-1194
    • Dresen, S.1    Ferreirós, N.2    Pütz, M.3    Westphal, F.4    Zimmermann, R.5    Auwärter, V.6
  • 22
    • 79960618509 scopus 로고    scopus 로고
    • Identification and quantitation of two benzoylindoles AM-694 and (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone, and three cannabimimetic naphthoylindoles JWH-210, JWH-122, and JWH-019 as adulterants in illegal products obtained via the Internet
    • Nakajima J., Takahashi M., Seto T., Kanai C., Suzuki J., Yoshida M., Hamano T. Identification and quantitation of two benzoylindoles AM-694 and (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone, and three cannabimimetic naphthoylindoles JWH-210, JWH-122, and JWH-019 as adulterants in illegal products obtained via the Internet. Forensic Toxicol. 2011, 29:95-110.
    • (2011) Forensic Toxicol. , vol.29 , pp. 95-110
    • Nakajima, J.1    Takahashi, M.2    Seto, T.3    Kanai, C.4    Suzuki, J.5    Yoshida, M.6    Hamano, T.7
  • 23
    • 77955897603 scopus 로고    scopus 로고
    • Use of high-resolution accurate mass spectrometry to detect reported and previously unreported cannabinomimetics in " herbal high" products
    • Hudson S., Ramsey J., King L., Timbers S., Maynard S., Dargan P.I., Wood D.M. Use of high-resolution accurate mass spectrometry to detect reported and previously unreported cannabinomimetics in " herbal high" products. J. Anal. Toxicol. 2010, 34:252-260.
    • (2010) J. Anal. Toxicol. , vol.34 , pp. 252-260
    • Hudson, S.1    Ramsey, J.2    King, L.3    Timbers, S.4    Maynard, S.5    Dargan, P.I.6    Wood, D.M.7
  • 24
    • 77952291222 scopus 로고    scopus 로고
    • Chemical analysis of synthetic cannabinoids as designer drugs in herbal products
    • Uchiyama N., Kikura-Hanajiri R., Ogata J., Goda Y. Chemical analysis of synthetic cannabinoids as designer drugs in herbal products. Forensic Sci. Int. 2010, 198:31-38.
    • (2010) Forensic Sci. Int. , vol.198 , pp. 31-38
    • Uchiyama, N.1    Kikura-Hanajiri, R.2    Ogata, J.3    Goda, Y.4
  • 25
    • 84856358393 scopus 로고    scopus 로고
    • Identification of 1-butyl-3-(1-(4-methyl)naphthoyl)indole in a herbal mixture
    • Westphal F., Sönnichsen F.D., Thiemt S. Identification of 1-butyl-3-(1-(4-methyl)naphthoyl)indole in a herbal mixture. Forensic Sci. Int. 2012, 215:8-13.
    • (2012) Forensic Sci. Int. , vol.215 , pp. 8-13
    • Westphal, F.1    Sönnichsen, F.D.2    Thiemt, S.3
  • 27
    • 79955468228 scopus 로고    scopus 로고
    • Identification and characterization of JWH-122 used as new ingredient in " Spice-like" herbal incenses
    • Ernst L., Schiebel H.M., Theuring C., Lindigkeit R., Beuerle T. Identification and characterization of JWH-122 used as new ingredient in " Spice-like" herbal incenses. Forensic Sci. Int. 2011, 208:e31-e35.
    • (2011) Forensic Sci. Int. , vol.208
    • Ernst, L.1    Schiebel, H.M.2    Theuring, C.3    Lindigkeit, R.4    Beuerle, T.5
  • 28
    • 79251632165 scopus 로고    scopus 로고
    • Identification and quantitation of two cannabimimetic phenylacetylindoles JWH-251 and JWH-250, and four cannabimimetic naphthoylindoles JWH-081, JWH-015, JWH-200, and JWH-073 as designer drugs in illegal products
    • Uchiyama N., Kawamura M., Kikura-Hanajiri R., Goda Y. Identification and quantitation of two cannabimimetic phenylacetylindoles JWH-251 and JWH-250, and four cannabimimetic naphthoylindoles JWH-081, JWH-015, JWH-200, and JWH-073 as designer drugs in illegal products. Forensic Toxicol. 2011, 29:25-37.
    • (2011) Forensic Toxicol. , vol.29 , pp. 25-37
    • Uchiyama, N.1    Kawamura, M.2    Kikura-Hanajiri, R.3    Goda, Y.4
  • 29
    • 79960614744 scopus 로고    scopus 로고
    • The emergence and analysis of synthetic cannabinoids
    • Hudson S., Ramsey J. The emergence and analysis of synthetic cannabinoids. Drug Test. Anal. 2011, 3:466-478.
    • (2011) Drug Test. Anal. , vol.3 , pp. 466-478
    • Hudson, S.1    Ramsey, J.2
  • 30
    • 84555195234 scopus 로고    scopus 로고
    • Recent advances in the application of CE to forensic sciences, an update over years 2009-2011
    • Pascali J.P., Bortolotti F., Tagliaro F. Recent advances in the application of CE to forensic sciences, an update over years 2009-2011. Electrophoresis 2012, 33:117-126.
    • (2012) Electrophoresis , vol.33 , pp. 117-126
    • Pascali, J.P.1    Bortolotti, F.2    Tagliaro, F.3
  • 31
    • 34447272734 scopus 로고    scopus 로고
    • Broad-spectrum toxicological analysis of hair based on capillary zone electrophoresis-time-of-flight mass spectrometry
    • Gottardo R., Fanigliulo A., Bortolotti F., De Paoli G., Pascali J.P., Tagliaro F. Broad-spectrum toxicological analysis of hair based on capillary zone electrophoresis-time-of-flight mass spectrometry. J. Chromatogr. A 2007, 1159:190-197.
    • (2007) J. Chromatogr. A , vol.1159 , pp. 190-197
    • Gottardo, R.1    Fanigliulo, A.2    Bortolotti, F.3    De Paoli, G.4    Pascali, J.P.5    Tagliaro, F.6
  • 32
    • 56849094898 scopus 로고    scopus 로고
    • Capillary zone electrophoresis (CZE) coupled to time-of-flight mass spectrometry (TOF-MS) applied to the analysis of illicit and controlled drugs in blood
    • Gottardo R., Polettini A., Sorio D., Pascali J.P., Bortolotti F., Liotta E., Tagliaro F. Capillary zone electrophoresis (CZE) coupled to time-of-flight mass spectrometry (TOF-MS) applied to the analysis of illicit and controlled drugs in blood. Electrophoresis 2008, 29:4078-4087.
    • (2008) Electrophoresis , vol.29 , pp. 4078-4087
    • Gottardo, R.1    Polettini, A.2    Sorio, D.3    Pascali, J.P.4    Bortolotti, F.5    Liotta, E.6    Tagliaro, F.7
  • 35
    • 0024083278 scopus 로고
    • Separation efficiency of slurry-packed liquid chromatography microcolumns with very small inner diameters
    • Karlsson K.E., Novotny M. Separation efficiency of slurry-packed liquid chromatography microcolumns with very small inner diameters. Anal. Chem. 1988, 60:1662-1665.
    • (1988) Anal. Chem. , vol.60 , pp. 1662-1665
    • Karlsson, K.E.1    Novotny, M.2
  • 37
    • 79451470676 scopus 로고    scopus 로고
    • Recent advances in micro-scale and nano-scale high-performance liquid-phase chromatography for proteome research
    • Dingyin T., Lihua Z., Yichu S., Zhen L., Yukui Z. Recent advances in micro-scale and nano-scale high-performance liquid-phase chromatography for proteome research. Anal. Bioanal. Chem. 2011, 399:229-241.
    • (2011) Anal. Bioanal. Chem. , vol.399 , pp. 229-241
    • Dingyin, T.1    Lihua, Z.2    Yichu, S.3    Zhen, L.4    Yukui, Z.5
  • 38
    • 78650177091 scopus 로고    scopus 로고
    • Investigation of polar stationary phases for the separation of sympathomimetic drugs with nano-liquid chromatography in hydrophilic interaction liquid chromatography mode
    • Aturki Z., D'Orazio G., Rocco A., Si-Ahmed K., Fanali S. Investigation of polar stationary phases for the separation of sympathomimetic drugs with nano-liquid chromatography in hydrophilic interaction liquid chromatography mode. Anal. Chim. Acta 2011, 685:103-110.
    • (2011) Anal. Chim. Acta , vol.685 , pp. 103-110
    • Aturki, Z.1    D'Orazio, G.2    Rocco, A.3    Si-Ahmed, K.4    Fanali, S.5
  • 39
    • 84858793329 scopus 로고    scopus 로고
    • Analysis of polyphenols and methylxanthines in tea samples by means of nano-liquid chromatography utilizing capillary columns packed with core-shell particles
    • Fanali C., Rocco A., Aturki Z., Mondello L., Fanali S. Analysis of polyphenols and methylxanthines in tea samples by means of nano-liquid chromatography utilizing capillary columns packed with core-shell particles. J. Chromatogr. A 2012, 1234:38-44.
    • (2012) J. Chromatogr. A , vol.1234 , pp. 38-44
    • Fanali, C.1    Rocco, A.2    Aturki, Z.3    Mondello, L.4    Fanali, S.5
  • 40
    • 0037420210 scopus 로고    scopus 로고
    • Matrix-assisted laser-desorption time-of flight ionization and high-performance liquid chromatography-electrospray ionization mass spectral analyses of two glycosylated recombinant epoetins
    • Stanley S.M.R., Poljak A. Matrix-assisted laser-desorption time-of flight ionization and high-performance liquid chromatography-electrospray ionization mass spectral analyses of two glycosylated recombinant epoetins. J. Chromatogr. B 2003, 785:205-218.
    • (2003) J. Chromatogr. B , vol.785 , pp. 205-218
    • Stanley, S.M.R.1    Poljak, A.2
  • 41
    • 77951252448 scopus 로고    scopus 로고
    • Doping control analysis of recombinant human erythropoietin, darbepoetin alfa and methoxy polyethylene glycol-epoetin beta in equine plasma by nano-liquid chromatography-tandem mass spectrometry
    • Yu Nola H., Ho Emmie N.M., Wan Terence S.M., Wong April S.Y. Doping control analysis of recombinant human erythropoietin, darbepoetin alfa and methoxy polyethylene glycol-epoetin beta in equine plasma by nano-liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 2010, 396:2513-2521.
    • (2010) Anal. Bioanal. Chem. , vol.396 , pp. 2513-2521
    • Yu Nola, H.1    Ho Emmie, N.M.2    Wan Terence, S.M.3    Wong April, S.Y.4
  • 43
    • 34247602952 scopus 로고    scopus 로고
    • Separation of basic compounds of pharmaceutical interest by using nano-liquid chromatography coupled with mass spectrometry
    • Fanali S., Aturki Z., D'Orazio G., Rocco A. Separation of basic compounds of pharmaceutical interest by using nano-liquid chromatography coupled with mass spectrometry. J. Chromatogr. A 2007, 1150:252-258.
    • (2007) J. Chromatogr. A , vol.1150 , pp. 252-258
    • Fanali, S.1    Aturki, Z.2    D'Orazio, G.3    Rocco, A.4
  • 44
    • 43049117450 scopus 로고    scopus 로고
    • Capillary liquid chromatography and capillary electrochromatography using silica hydride stationary phases
    • Pesek J.J., Matyska M.T., Sukul D. Capillary liquid chromatography and capillary electrochromatography using silica hydride stationary phases. J. Chromatogr. A 2008, 1191:136-140.
    • (2008) J. Chromatogr. A , vol.1191 , pp. 136-140
    • Pesek, J.J.1    Matyska, M.T.2    Sukul, D.3


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