Expanding chemical diversity of conotoxins: Peptoid-peptide chimeras of the sodium channel blocker μ-KIIIA and its selenopeptide analogues

European Journal of Medicinal Chemistry

Volumn 65, Issue , 2013, Pages 144-150

  Walewska, Aleksandra ^a   Han, Tiffany S ^b   Zhang, Min Min ^b   Yoshikami, Doju ^b   Bulaj, Grzegorz ^b   Rolka, Krzysztof ^a  

^a UNIVERSITY OF GDA SK   (Poland)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Diselenide; Electrophysiology; KIIIA; Peptomers; Selenocysteine; Sodium channels; conotoxins

Indexed keywords

ANALGESIC AGENT; CONOTOXIN; GLYCINE DERIVATIVE; MU CONOTOXIN KIIIA; N BUTYLGLYCINE; N OCTYLGLYCINE; PEPTIDOMIMETIC AGENT; SARCOSINE; SELENOCYSTEINE; SODIUM CHANNEL NAV1.2; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL BLOCKING AGENT;

ARTICLE; BIOLOGICAL ACTIVITY; CHIMERA; ELECTROPHYSIOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR INTERACTION; NONHUMAN; OOCYTE; PHYSICAL CHEMISTRY; SODIUM CURRENT; SOLID PHASE SYNTHESIS; SYNTHESIS; XENOPUS;

EID: 84878009040     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.04.041     Document Type: Article

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