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Angewandte Chemie - International Edition

Volumn 50, Issue 29, 2011, Pages 6527-6529

Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding

(10) De Araujo, Aline Dantas a Callaghan, Brid b Nevin, Simon T a Daly, Norelle L a Craik, David J a Moretta, Melissa c Hopping, Gene a Christie, MacDonald J c Adams, David J b Alewood, Paul F a

a UNIVERSITY OF QUEENSLAND (Australia)

b RMIT UNIVERSITY (Australia)

c UNIVERSITY OF SYDNEY (Australia)

Author keywords

disulfides; ion channels; peptides; regioselective folding; selenocysteine

Indexed keywords

CONOTOXINS; DISULFIDE BONDS; DISULFIDES; ION CHANNELS; REGIO-SELECTIVE; SELENOCYSTEINE; THERAPEUTIC POTENTIALS; TOTAL SYNTHESIS;

COVALENT BONDS;

PEPTIDES;

ANALGESIC AGENT; CONOTOXIN; MUO CONOTOXIN MRVIB; MUO-CONOTOXIN MRVIB; SELENOCYSTEINE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; IC 50; MOLECULAR GENETICS; NERVE CELL; PROTEIN FOLDING; SPINAL GANGLION; SYNTHESIS; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANALGESICS; ANIMALS; CONOTOXINS; GANGLIA, SPINAL; INHIBITORY CONCENTRATION 50; MOLECULAR SEQUENCE DATA; NEURONS; PROTEIN FOLDING; SELENOCYSTEINE; XENOPUS LAEVIS;

EID: 79959935844 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201101642 Document Type: Article

Times cited : (77)

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