Adenine-DNA adducts derived from the highly tumorigenic dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not

Chemical Research in Toxicology

Volumn 26, Issue 5, 2013, Pages 783-793

  Kropachev, Konstantin ^a   Kolbanovskiy, Marina ^a   Liu, Zhi ^a   Cai, Yuqin ^a   Zhang, Lu ^a   Schwaid, Adam G ^a,c   Kolbanovskiy, Alexander ^a   Ding, Shuang ^a   Amin, Shantu ^b   Broyde, Suse ^a   Geacintov, Nicholas E ^a  

^a NEW YORK UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CELL EXTRACT; DIBENZO[A,L]PYREN; EPOXIDE; GUANINE; PYRENE DERIVATIVE; UNCLASSIFIED DRUG; BENZO[A]PYRENE DERIVATIVE; DIBENZO(A,L)PYRENE; DNA ADDUCT;

ARTICLE; CONTROLLED STUDY; DNA ADDUCT; ENANTIOMER; EXCISION REPAIR; GENOTOXICITY; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; STEREOCHEMISTRY; THERMOSTABILITY; CHEMICAL STRUCTURE; CHEMISTRY; DNA REPAIR; DRUG EFFECTS; HELA CELL LINE; MOLECULAR DYNAMICS; STRUCTURE ACTIVITY RELATION; TEMPERATURE; TOXICITY;

ADENINE; BENZOPYRENES; DNA ADDUCTS; DNA REPAIR; GUANINE; HELA CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

EID: 84877997319     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx400080k     Document Type: Article

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