Nuclear magnetic resonance solution structure of an N2-guanine DNA adduct derived from the potent tumorigen dibenzo[a, l]pyrene: Intercalation from the minor groove with ruptured Watson-Crick base pairing

Biochemistry

Volumn 51, Issue 48, 2012, Pages 9751-9762

  Tang, Yijin ^a   Liu, Zhi ^a   Ding, Shuang ^a   Lin, Chin H ^a   Cai, Yuqin ^a   Rodriguez, Fabian A ^a   Sayer, Jane M ^b,d   Jerina, Donald M ^b   Amin, Shantu ^c   Broyde, Suse ^a   Geacintov, Nicholas E ^a  

^a NEW YORK UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO GROUP; DNA ADDUCTS; DNA BASIS; DNA LESIONS; DOUBLE STRANDED DNA; IN-VIVO; LESION SITE; MINOR GROOVES; MODIFIED GUANINE; NUCLEOTIDE EXCISION REPAIR; RING SYSTEMS; SOLUTION STRUCTURES; WATSON-CRICK BASE PAIRING;

NUCLEAR MAGNETIC RESONANCE; POSITIVE IONS; PYRENE;

DNA;

CYTOSINE; DEOXYGUANOSINE; DIBENZO[A,L]PYRENE; DNA; DOUBLE STRANDED DNA; GUANINE DERIVATIVE;

ARTICLE; BASE PAIRING; CHEMICAL STRUCTURE; DNA ADDUCT; DNA CONFORMATION; EXCISION REPAIR; INTERCALATION COMPLEX; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STEREOCHEMISTRY; SYNTHESIS; WATSON CRICK BASE PAIRING;

BASE PAIRING; BENZOPYRENES; DNA ADDUCTS; GUANINE; MOLECULAR DYNAMICS SIMULATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION;

EID: 84870522870     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3013577     Document Type: Article

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