Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactions

Biochemistry

Volumn 51, Issue 7, 2012, Pages 1486-1499

  Cai, Yuqin ^a   Geacintov, Nicholas E ^a   Broyde, Suse ^a  

^a NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC RINGS; DNA ADDUCTS; DNA DAMAGES; DNA DUPLEXES; DNA LESIONS; IDEAL MODEL; NUCLEOTIDE EXCISION REPAIR; STACKING INTERACTION; VAN DER WAALS;

EFFICIENCY; MACHINERY; MAMMALS; MOLECULAR DYNAMICS; NUCLEOTIDES; POLYCYCLIC AROMATIC HYDROCARBONS; REPAIR; STEREOCHEMISTRY; STEREOSELECTIVITY; TOPOLOGY; VAN DER WAALS FORCES;

DNA;

ADENINE; CARCINOGEN; DNA; DNA BASE; DOUBLE STRANDED DNA; EPOXIDE; POLYCYCLIC AROMATIC HYDROCARBON;

ARTICLE; CARCINOGEN DNA INTERACTION; CARCINOGENICITY; CHEMICAL STRUCTURE; DNA ADDUCT; ENERGY; EXCISION REPAIR; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR STABILITY; PRIORITY JOURNAL; STEREOCHEMISTRY; STEREOISOMERISM; STEREOSPECIFICITY; THERMODYNAMICS; THERMOSTABILITY;

CARCINOGENS; DNA; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; HYDROGEN BONDING; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; NUCLEOTIDES; POLYCYCLIC HYDROCARBONS, AROMATIC; SACCHAROMYCES CEREVISIAE; STEREOISOMERISM; THERMODYNAMICS;

EID: 84857382560     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201794x     Document Type: Article

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