Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts

Nucleic Acids Research

Volumn 40, Issue 6, 2012, Pages 2494-2505

  Sidorenko, Victoria S ^a   Yeo, Jung Eun ^a   Bonala, Radha R ^a   Johnson, Francis ^a   Schärer, Orlando D ^a   Grollman, Arthur P ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARISTOLOCHIC ACID; ARISTOLOLACTAM; BINDING PROTEIN; RAD23B PROTEIN; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP C PROTEIN;

ARTICLE; BINDING AFFINITY; CELL VIABILITY; CODON; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA ADDUCT; DNA BINDING; DNA STRAND; EXCISION REPAIR; FIBROBLAST CULTURE; GENE EXPRESSION REGULATION; GENE MUTATION; GENOME ANALYSIS; GENOTOXICITY; HUMAN; HUMAN CELL; MISMATCH REPAIR; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; MUTAGENICITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

ADENINE; ARISTOLOCHIC ACIDS; CELL LINE; DNA ADDUCTS; DNA REPAIR; DNA-BINDING PROTEINS; GENOME, HUMAN; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; MUTAGENESIS; MUTAGENS;

ARISTOLOCHIA;

EID: 84859329706     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr1095     Document Type: Article

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