Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context

Nucleic Acids Research

Volumn 35, Issue 5, 2007, Pages 1555-1568

  Rodríguez, Fabián A ^a   Cai, Yuqin ^a   Lin, Chin ^a   Tang, Yijin ^a   Kolbanovskiy, Alexander ^a   Amin, Shantu ^b   Patel, Dinshaw J ^c   Broyde, Suse ^a   Geacintov, Nicholas E ^a  

^a NEW YORK UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CYTOSINE; DOUBLE STRANDED DNA; GUANINE;

ARTICLE; BASE PAIRING; DNA ADDUCT; DNA CONFORMATION; DNA DENATURATION; DNA FLANKING REGION; DNA STRAND; DNA STRUCTURE; ELECTROPHORETIC MOBILITY; GENE MUTATION; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; SEQUENCE ANALYSIS;

AMINES; BASE SEQUENCE; BENZOPYRENES; DEOXYGUANOSINE; DNA ADDUCTS; GUANINE; MODELS, MOLECULAR; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; PROTONS; TEMPERATURE;

EID: 34247213435     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm022     Document Type: Article

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