메뉴 건너뛰기




Volumn 50, Issue SUPPL.1, 2013, Pages

DNA methylation and primary immune thrombocytopenia

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD40 LIGAND; CD5 ANTIGEN; CD70 ANTIGEN; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GAMMA INTERFERON; HISTONE DEACETYLASE; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; METHYL CPG BINDING PROTEIN; METHYL CPG BINDING PROTEIN 4; PERFORIN; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

EID: 84877658001     PISSN: 00371963     EISSN: 15328686     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2013.03.022     Document Type: Article
Times cited : (14)

References (129)
  • 1
    • 0026503767 scopus 로고
    • Systemic lupus erythematosus and related systemic diseases in a nationwide twin cohort: an increased prevalence of disease in MZ twins and concordance of disease features
    • Jarvinen P., Kaprio J., Makitalo R., Koskenvuo M., Aho K. Systemic lupus erythematosus and related systemic diseases in a nationwide twin cohort: an increased prevalence of disease in MZ twins and concordance of disease features. J Intern Med 1992, 231:67-72.
    • (1992) J Intern Med , vol.231 , pp. 67-72
    • Jarvinen, P.1    Kaprio, J.2    Makitalo, R.3    Koskenvuo, M.4    Aho, K.5
  • 2
    • 0029128706 scopus 로고
    • Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins
    • Kyvik K.O., Green A., Beck-Nielsen H. Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins. BMJ 1995, 311:913-917.
    • (1995) BMJ , vol.311 , pp. 913-917
    • Kyvik, K.O.1    Green, A.2    Beck-Nielsen, H.3
  • 3
    • 0023024826 scopus 로고
    • Occurrence of rheumatoid arthritis in a nationwide series of twins
    • Aho K., Koskenvuo M., Tuominen J., Kaprio J. Occurrence of rheumatoid arthritis in a nationwide series of twins. J Rheumatol 1986, 13:899-902.
    • (1986) J Rheumatol , vol.13 , pp. 899-902
    • Aho, K.1    Koskenvuo, M.2    Tuominen, J.3    Kaprio, J.4
  • 5
    • 65249142729 scopus 로고    scopus 로고
    • Rapid DNA methylation changes after exposure to traffic particles
    • Baccarelli A., Wright R.O., Bollati V., et al. Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med 2009, 179:572-578.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 572-578
    • Baccarelli, A.1    Wright, R.O.2    Bollati, V.3
  • 6
    • 60749124259 scopus 로고    scopus 로고
    • Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation
    • Tarantini L., Bonzini M., Apostoli P., et al. Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation. Environ Health Perspect 2009, 117:217-222.
    • (2009) Environ Health Perspect , vol.117 , pp. 217-222
    • Tarantini, L.1    Bonzini, M.2    Apostoli, P.3
  • 7
    • 80052943106 scopus 로고    scopus 로고
    • Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development
    • Niles K.M., Chan D., La Salle S., Oakes C.C., Trasler J.M. Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development. PLoS One 2011, 6:e24156.
    • (2011) PLoS One , vol.6
    • Niles, K.M.1    Chan, D.2    La Salle, S.3    Oakes, C.C.4    Trasler, J.M.5
  • 8
    • 79955777417 scopus 로고    scopus 로고
    • Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
    • Liang P., Song F., Ghosh S., et al. Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development. BMC Genomics 2011, 12:231.
    • (2011) BMC Genomics , vol.12 , pp. 231
    • Liang, P.1    Song, F.2    Ghosh, S.3
  • 9
    • 0019510628 scopus 로고
    • Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation
    • Mohandas T., Sparkes R.S., Shapiro L.J. Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. Science 1981, 211:393-396.
    • (1981) Science , vol.211 , pp. 393-396
    • Mohandas, T.1    Sparkes, R.S.2    Shapiro, L.J.3
  • 11
    • 0019325954 scopus 로고
    • Determination of S-adenosylmethionine and S-adenosylhomocysteine in nuclei isolated from sea urchin embryos during early development
    • Branno M. Determination of S-adenosylmethionine and S-adenosylhomocysteine in nuclei isolated from sea urchin embryos during early development. Boll Soc Ital Biol Sper 1980, 56:1769-1771.
    • (1980) Boll Soc Ital Biol Sper , vol.56 , pp. 1769-1771
    • Branno, M.1
  • 12
    • 0016692220 scopus 로고
    • X inactivation, differentiation, and DNA methylation
    • Riggs A.D. X inactivation, differentiation, and DNA methylation. Cytogenet Cell Genet 1975, 14:9-25.
    • (1975) Cytogenet Cell Genet , vol.14 , pp. 9-25
    • Riggs, A.D.1
  • 13
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M., Bell D.W., Haber D.A., Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 14
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Okano M., Xie S., Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat Genet 1998, 19:219-220.
    • (1998) Nat Genet , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 15
    • 0032102949 scopus 로고    scopus 로고
    • Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells
    • Okano M., Xie S., Li E. Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells. Nucleic Acids Res 1998, 26:2536-2540.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2536-2540
    • Okano, M.1    Xie, S.2    Li, E.3
  • 16
    • 0041355334 scopus 로고    scopus 로고
    • The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity
    • Hermann A., Schmitt S., Jeltsch A. The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity. J Biol Chem 2003, 278:31717-31721.
    • (2003) J Biol Chem , vol.278 , pp. 31717-31721
    • Hermann, A.1    Schmitt, S.2    Jeltsch, A.3
  • 17
    • 31144449613 scopus 로고    scopus 로고
    • Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2
    • Goll M.G., Kirpekar F., Maggert K.A., et al. Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science 2006, 311:395-398.
    • (2006) Science , vol.311 , pp. 395-398
    • Goll, M.G.1    Kirpekar, F.2    Maggert, K.A.3
  • 18
    • 0036713390 scopus 로고    scopus 로고
    • Dnmt3L is a transcriptional repressor that recruits histone deacetylase
    • Deplus R., Brenner C., Burgers W.A., et al. Dnmt3L is a transcriptional repressor that recruits histone deacetylase. Nucleic Acids Res 2002, 30:3831-3838.
    • (2002) Nucleic Acids Res , vol.30 , pp. 3831-3838
    • Deplus, R.1    Brenner, C.2    Burgers, W.A.3
  • 19
    • 0037168587 scopus 로고    scopus 로고
    • The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a
    • Chedin F., Lieber M.R., Hsieh C.L. The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. Proc Natl Acad Sci U S A 2002, 99:16916-16921.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16916-16921
    • Chedin, F.1    Lieber, M.R.2    Hsieh, C.L.3
  • 20
    • 0036333103 scopus 로고    scopus 로고
    • Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice
    • Hata K., Okano M., Lei H., Li E. Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development 2002, 129:1983-1993.
    • (2002) Development , vol.129 , pp. 1983-1993
    • Hata, K.1    Okano, M.2    Lei, H.3    Li, E.4
  • 21
    • 34249672387 scopus 로고    scopus 로고
    • Variations in DNA methylation patterns during the cell cycle of HeLa cells
    • Brown S.E., Fraga M.F., Weaver I.C., Berdasco M., Szyf M. Variations in DNA methylation patterns during the cell cycle of HeLa cells. Epigenetics 2007, 2:54-65.
    • (2007) Epigenetics , vol.2 , pp. 54-65
    • Brown, S.E.1    Fraga, M.F.2    Weaver, I.C.3    Berdasco, M.4    Szyf, M.5
  • 22
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • Bhattacharya S.K., Ramchandani S., Cervoni N., Szyf M. A mammalian protein with specific demethylase activity for mCpG DNA. Nature 1999, 397:579-583.
    • (1999) Nature , vol.397 , pp. 579-583
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 23
    • 0024081657 scopus 로고
    • Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter
    • Watt F., Molloy P.L. Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev 1988, 2:1136-1143.
    • (1988) Genes Dev , vol.2 , pp. 1136-1143
    • Watt, F.1    Molloy, P.L.2
  • 24
    • 0036493248 scopus 로고    scopus 로고
    • Methylation-dependent silencing at the H19 imprinting control region by MeCP2
    • Drewell R.A., Goddard C.J., Thomas J.O., Surani M.A. Methylation-dependent silencing at the H19 imprinting control region by MeCP2. Nucleic Acids Res 2002, 30:1139-1144.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1139-1144
    • Drewell, R.A.1    Goddard, C.J.2    Thomas, J.O.3    Surani, M.A.4
  • 25
    • 0037591867 scopus 로고    scopus 로고
    • Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression
    • Fujita N., Watanabe S., Ichimura T., et al. Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression. J Biol Chem 2003, 278:24132-24138.
    • (2003) J Biol Chem , vol.278 , pp. 24132-24138
    • Fujita, N.1    Watanabe, S.2    Ichimura, T.3
  • 26
    • 0024802174 scopus 로고
    • Age-related methylation changes in DNA may reflect the proliferative potential of organs
    • Hoal-van Helden E.G., van Helden P.D. Age-related methylation changes in DNA may reflect the proliferative potential of organs. Mutat Res 1989, 219:263-266.
    • (1989) Mutat Res , vol.219 , pp. 263-266
    • Hoal-van Helden, E.G.1    van Helden, P.D.2
  • 27
    • 0036322831 scopus 로고    scopus 로고
    • Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring
    • Cooney C.A., Dave A.A., Wolff G.L. Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J Nutr 2002, 132:2393S-2400S.
    • (2002) J Nutr , vol.132
    • Cooney, C.A.1    Dave, A.A.2    Wolff, G.L.3
  • 28
    • 0013792533 scopus 로고
    • Inhibition of the methylation of nicotinamide by chlorpromazine
    • Salvador R.A., Burton R.M. Inhibition of the methylation of nicotinamide by chlorpromazine. Biochem Pharmacol 1965, 14:1185-1196.
    • (1965) Biochem Pharmacol , vol.14 , pp. 1185-1196
    • Salvador, R.A.1    Burton, R.M.2
  • 29
    • 0025281055 scopus 로고
    • CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation
    • Richardson B.C., Liebling M.R., Hudson J.L. CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation. Clin Immunol Immunopathol 1990, 55:368-381.
    • (1990) Clin Immunol Immunopathol , vol.55 , pp. 368-381
    • Richardson, B.C.1    Liebling, M.R.2    Hudson, J.L.3
  • 30
    • 0023857234 scopus 로고
    • Differential inhibition of mitogen induced T cell proliferation by 5-azacytidine and cytosine-arabinoside
    • Schauenstein K., Rossi K., Csordas A. Differential inhibition of mitogen induced T cell proliferation by 5-azacytidine and cytosine-arabinoside. Biochem Biophys Res Commun 1988, 151:548-553.
    • (1988) Biochem Biophys Res Commun , vol.151 , pp. 548-553
    • Schauenstein, K.1    Rossi, K.2    Csordas, A.3
  • 31
    • 0027257146 scopus 로고
    • Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice
    • Quddus J., Johnson K.J., Gavalchin J., et al. Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice. J Clin Invest 1993, 92:38-53.
    • (1993) J Clin Invest , vol.92 , pp. 38-53
    • Quddus, J.1    Johnson, K.J.2    Gavalchin, J.3
  • 32
    • 84859924136 scopus 로고    scopus 로고
    • A whole genome methylation analysis of systemic lupus erythematosus: hypomethylation of the IL10 and IL1R2 promoters is associated with disease activity
    • Lin S.Y., Hsieh S.C., Lin Y.C., et al. A whole genome methylation analysis of systemic lupus erythematosus: hypomethylation of the IL10 and IL1R2 promoters is associated with disease activity. Genes Immun 2012, 13:214-220.
    • (2012) Genes Immun , vol.13 , pp. 214-220
    • Lin, S.Y.1    Hsieh, S.C.2    Lin, Y.C.3
  • 33
    • 0035096761 scopus 로고    scopus 로고
    • Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients
    • Deng C., Kaplan M.J., Yang J., et al. Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis Rheum 2001, 44:397-407.
    • (2001) Arthritis Rheum , vol.44 , pp. 397-407
    • Deng, C.1    Kaplan, M.J.2    Yang, J.3
  • 34
    • 44849087740 scopus 로고    scopus 로고
    • Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients
    • Sawalha A.H., Jeffries M., Webb R., et al. Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. Genes Immun 2008, 9:368-378.
    • (2008) Genes Immun , vol.9 , pp. 368-378
    • Sawalha, A.H.1    Jeffries, M.2    Webb, R.3
  • 35
    • 0023644247 scopus 로고
    • Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)
    • Marlin S.D., Springer T.A. Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Cell 1987, 51:813-819.
    • (1987) Cell , vol.51 , pp. 813-819
    • Marlin, S.D.1    Springer, T.A.2
  • 36
    • 0037097819 scopus 로고    scopus 로고
    • Effect of DNA methylation and chromatin structure on ITGAL expression
    • Lu Q., Ray D., Gutsch D., Richardson B. Effect of DNA methylation and chromatin structure on ITGAL expression. Blood 2002, 99:4503-4508.
    • (2002) Blood , vol.99 , pp. 4503-4508
    • Lu, Q.1    Ray, D.2    Gutsch, D.3    Richardson, B.4
  • 37
    • 0026741293 scopus 로고
    • Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus
    • Richardson B.C., Strahler J.R., Pivirotto T.S., et al. Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus. Arthritis Rheum 1992, 35:647-662.
    • (1992) Arthritis Rheum , vol.35 , pp. 647-662
    • Richardson, B.C.1    Strahler, J.R.2    Pivirotto, T.S.3
  • 38
    • 0033634930 scopus 로고    scopus 로고
    • DNA methylation in the regulation of T cell LFA-1 expression
    • Kaplan M.J., Deng C., Yang J., Richardson B.C. DNA methylation in the regulation of T cell LFA-1 expression. Immunol Invest 2000, 29:411-425.
    • (2000) Immunol Invest , vol.29 , pp. 411-425
    • Kaplan, M.J.1    Deng, C.2    Yang, J.3    Richardson, B.C.4
  • 39
    • 0036095885 scopus 로고    scopus 로고
    • Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus
    • Lu Q., Kaplan M., Ray D., et al. Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus. Arthritis Rheum 2002, 46:1282-1291.
    • (2002) Arthritis Rheum , vol.46 , pp. 1282-1291
    • Lu, Q.1    Kaplan, M.2    Ray, D.3
  • 40
    • 2642556447 scopus 로고    scopus 로고
    • Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors
    • Oelke K., Lu Q., Richardson D., et al. Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors. Arthritis Rheum 2004, 50:1850-1860.
    • (2004) Arthritis Rheum , vol.50 , pp. 1850-1860
    • Oelke, K.1    Lu, Q.2    Richardson, D.3
  • 41
    • 18644376210 scopus 로고    scopus 로고
    • Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs
    • Lu Q., Wu A., Richardson B.C. Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. J Immunol 2005, 174:6212-6219.
    • (2005) J Immunol , vol.174 , pp. 6212-6219
    • Lu, Q.1    Wu, A.2    Richardson, B.C.3
  • 42
    • 77951231981 scopus 로고    scopus 로고
    • Demethylation of promoter regulatory elements contributes to CD70 overexpression in CD4+ T cells from patients with subacute cutaneous lupus erythematosus
    • Luo Y., Zhao M., Lu Q. Demethylation of promoter regulatory elements contributes to CD70 overexpression in CD4+ T cells from patients with subacute cutaneous lupus erythematosus. Clin Exp Dermatol 2010, 35:425-430.
    • (2010) Clin Exp Dermatol , vol.35 , pp. 425-430
    • Luo, Y.1    Zhao, M.2    Lu, Q.3
  • 43
    • 77956174695 scopus 로고    scopus 로고
    • Hypomethylation and overexpression of CD70 (TNFSF7) in CD4+ T cells of patients with primary Sjogren's syndrome
    • Yin H., Zhao M., Wu X., et al. Hypomethylation and overexpression of CD70 (TNFSF7) in CD4+ T cells of patients with primary Sjogren's syndrome. J Dermatol Sci 2010, 59:198-203.
    • (2010) J Dermatol Sci , vol.59 , pp. 198-203
    • Yin, H.1    Zhao, M.2    Wu, X.3
  • 44
    • 84862777126 scopus 로고    scopus 로고
    • Demethylation of TNFSF7 contributes to CD70 overexpression in CD4+ T cells from patients with systemic sclerosis
    • Jiang H., Xiao R., Lian X., et al. Demethylation of TNFSF7 contributes to CD70 overexpression in CD4+ T cells from patients with systemic sclerosis. Clin Immunol 2012, 143:39-44.
    • (2012) Clin Immunol , vol.143 , pp. 39-44
    • Jiang, H.1    Xiao, R.2    Lian, X.3
  • 45
    • 79957803679 scopus 로고    scopus 로고
    • Increased expressions of DNA methyltransferases contribute to CD70 promoter hypomethylation and over expression of CD70 in ITP
    • Ma L., Zhou Z., Wang H., et al. Increased expressions of DNA methyltransferases contribute to CD70 promoter hypomethylation and over expression of CD70 in ITP. Mol Immunol 2011, 48:1525-1531.
    • (2011) Mol Immunol , vol.48 , pp. 1525-1531
    • Ma, L.1    Zhou, Z.2    Wang, H.3
  • 46
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann T.R., Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996, 17:138-146.
    • (1996) Immunol Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 47
    • 0028986033 scopus 로고
    • Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo
    • Yung R.L., Quddus J., Chrisp C.E., Johnson K.J., Richardson B.C. Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo. J Immunol 1995, 154:3025-3035.
    • (1995) J Immunol , vol.154 , pp. 3025-3035
    • Yung, R.L.1    Quddus, J.2    Chrisp, C.E.3    Johnson, K.J.4    Richardson, B.C.5
  • 48
    • 0041929384 scopus 로고    scopus 로고
    • Effect of promoter methylation on the regulation of IFN-gamma gene during in vitro differentiation of human peripheral blood T cells into a Th2 population
    • Yano S., Ghosh P., Kusaba H., Buchholz M., Longo D.L. Effect of promoter methylation on the regulation of IFN-gamma gene during in vitro differentiation of human peripheral blood T cells into a Th2 population. J Immunol 2003, 171:2510-2516.
    • (2003) J Immunol , vol.171 , pp. 2510-2516
    • Yano, S.1    Ghosh, P.2    Kusaba, H.3    Buchholz, M.4    Longo, D.L.5
  • 49
    • 0031808712 scopus 로고    scopus 로고
    • IL-4 and prostaglandin E2 inhibit hypomethylation of the 5' regulatory region of IFN-gamma gene during differentiation of naive CD4+ T cells
    • Katamura K., Fukui T., Kiyomasu T., et al. IL-4 and prostaglandin E2 inhibit hypomethylation of the 5' regulatory region of IFN-gamma gene during differentiation of naive CD4+ T cells. Mol Immunol 1998, 35:39-45.
    • (1998) Mol Immunol , vol.35 , pp. 39-45
    • Katamura, K.1    Fukui, T.2    Kiyomasu, T.3
  • 50
    • 0036279221 scopus 로고    scopus 로고
    • Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene
    • Lee D.U., Agarwal S., Rao A. Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene. Immunity 2002, 16:649-660.
    • (2002) Immunity , vol.16 , pp. 649-660
    • Lee, D.U.1    Agarwal, S.2    Rao, A.3
  • 51
    • 40149105740 scopus 로고    scopus 로고
    • DNA methylation and the expression of IL-4 and IFN-gamma promoter genes in patients with bronchial asthma
    • Kwon N.H., Kim J.S., Lee J.Y., Oh M.J., Choi D.C. DNA methylation and the expression of IL-4 and IFN-gamma promoter genes in patients with bronchial asthma. J Clin Immunol 2008, 28:139-146.
    • (2008) J Clin Immunol , vol.28 , pp. 139-146
    • Kwon, N.H.1    Kim, J.S.2    Lee, J.Y.3    Oh, M.J.4    Choi, D.C.5
  • 52
    • 37848999684 scopus 로고    scopus 로고
    • Hypomethylation of interleukin-4 and -6 promoters in T cells from systemic lupus erythematosus patients
    • Mi X.B., Zeng F.Q. Hypomethylation of interleukin-4 and -6 promoters in T cells from systemic lupus erythematosus patients. Acta Pharmacol Sin 2008, 29:105-112.
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 105-112
    • Mi, X.B.1    Zeng, F.Q.2
  • 53
    • 59849085588 scopus 로고    scopus 로고
    • Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation
    • Lal G., Zhang N., van der Touw W., Ding Y., et al. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol 2009, 182:259-273.
    • (2009) J Immunol , vol.182 , pp. 259-273
    • Lal, G.1    Zhang, N.2    van der Touw, W.3    Ding, Y.4
  • 54
    • 34548755672 scopus 로고    scopus 로고
    • DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells
    • Baron U., Floess S., Wieczorek G., et al. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells. Eur J Immunol 2007, 37:2378-2389.
    • (2007) Eur J Immunol , vol.37 , pp. 2378-2389
    • Baron, U.1    Floess, S.2    Wieczorek, G.3
  • 55
    • 34447265236 scopus 로고    scopus 로고
    • Leo. Abnormal DNA methylation in CD4+ T cells from people with latent autoimmune diabetes in adults. nard WJ. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation
    • Kim H.P. Leo. Abnormal DNA methylation in CD4+ T cells from people with latent autoimmune diabetes in adults. nard WJ. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. J Exp Med 2007, 204:1543-1551.
    • (2007) J Exp Med , vol.204 , pp. 1543-1551
    • Kim, H.P.1
  • 56
    • 81255157792 scopus 로고    scopus 로고
    • Abnormal DNA methylation in CD4+ T cells from people with latent autoimmune diabetes in adults
    • Li Y., Zhao M., Hou C., et al. Abnormal DNA methylation in CD4+ T cells from people with latent autoimmune diabetes in adults. Diabetes Res Clin Pract 2011, 94:242-248.
    • (2011) Diabetes Res Clin Pract , vol.94 , pp. 242-248
    • Li, Y.1    Zhao, M.2    Hou, C.3
  • 58
    • 0037884760 scopus 로고    scopus 로고
    • DNA methylation and chromatin structure regulate T cell perforin gene expression
    • Lu Q., Wu A., Ray D., et al. DNA methylation and chromatin structure regulate T cell perforin gene expression. J Immunol 2003, 170:5124-5132.
    • (2003) J Immunol , vol.170 , pp. 5124-5132
    • Lu, Q.1    Wu, A.2    Ray, D.3
  • 59
    • 33846285424 scopus 로고    scopus 로고
    • Effects of 5-azaC on methylation pattern of the perforin promoter of the perforin gene in normal human T cells
    • Xiao R., Ding Y., Lu Q.J., et al. Effects of 5-azaC on methylation pattern of the perforin promoter of the perforin gene in normal human T cells. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006, 31:843-847.
    • (2006) Zhong Nan Da Xue Xue Bao Yi Xue Ban , vol.31 , pp. 843-847
    • Xiao, R.1    Ding, Y.2    Lu, Q.J.3
  • 60
    • 1542724431 scopus 로고    scopus 로고
    • Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells
    • Kaplan M.J., Lu Q., Wu A., Attwood J., Richardson B. Demethylation of promoter regulatory elements contributes to perforin overexpression in CD4+ lupus T cells. J Immunol 2004, 172:3652-3661.
    • (2004) J Immunol , vol.172 , pp. 3652-3661
    • Kaplan, M.J.1    Lu, Q.2    Wu, A.3    Attwood, J.4    Richardson, B.5
  • 61
    • 69049083293 scopus 로고    scopus 로고
    • DNA demethylation of the perforin promoter in CD4(+) T cells from patients with subacute cutaneous lupus erythematosus
    • Luo Y., Zhang X., Zhao M., Lu Q. DNA demethylation of the perforin promoter in CD4(+) T cells from patients with subacute cutaneous lupus erythematosus. J Dermatol Sci 2009, 56:33-36.
    • (2009) J Dermatol Sci , vol.56 , pp. 33-36
    • Luo, Y.1    Zhang, X.2    Zhao, M.3    Lu, Q.4
  • 63
    • 49449106856 scopus 로고    scopus 로고
    • Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis
    • Nile C.J., Read R.C., Akil M., Duff G.W., Wilson A.G. Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum 2008, 58:2686-2693.
    • (2008) Arthritis Rheum , vol.58 , pp. 2686-2693
    • Nile, C.J.1    Read, R.C.2    Akil, M.3    Duff, G.W.4    Wilson, A.G.5
  • 64
    • 84863685954 scopus 로고    scopus 로고
    • Interleukin-6 gene promoter methylation in rheumatoid arthritis and chronic periodontitis
    • Ishida K., Kobayashi T., Ito S., et al. Interleukin-6 gene promoter methylation in rheumatoid arthritis and chronic periodontitis. J Periodontol 2012, 83:917-925.
    • (2012) J Periodontol , vol.83 , pp. 917-925
    • Ishida, K.1    Kobayashi, T.2    Ito, S.3
  • 65
    • 0035955640 scopus 로고    scopus 로고
    • Interleukin-6 regulation of the human DNA methyltransferase (HDNMT) gene in human erythroleukemia cells
    • Hodge D.R., Xiao W., Clausen P.A., Heidecker G., Szyf M., Farrar W.L. Interleukin-6 regulation of the human DNA methyltransferase (HDNMT) gene in human erythroleukemia cells. J Biol Chem 2001, 276:39508-39511.
    • (2001) J Biol Chem , vol.276 , pp. 39508-39511
    • Hodge, D.R.1    Xiao, W.2    Clausen, P.A.3    Heidecker, G.4    Szyf, M.5    Farrar, W.L.6
  • 66
    • 0037340215 scopus 로고    scopus 로고
    • Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process
    • Bruniquel D., Schwartz R.H. Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process. Nat Immunol 2003, 4:235-240.
    • (2003) Nat Immunol , vol.4 , pp. 235-240
    • Bruniquel, D.1    Schwartz, R.H.2
  • 67
    • 33644854871 scopus 로고    scopus 로고
    • A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory
    • Murayama A., Sakura K., Nakama M., et al. A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory. Embo J 2006, 25:1081-1092.
    • (2006) Embo J , vol.25 , pp. 1081-1092
    • Murayama, A.1    Sakura, K.2    Nakama, M.3
  • 68
    • 84862780150 scopus 로고    scopus 로고
    • IL-2 and GM-CSF are regulated by DNA demethylation during activation of T cells, B cells and macrophages
    • Li Y., Ohms S.J., Shannon F.M., Sun C., Fan J.Y. IL-2 and GM-CSF are regulated by DNA demethylation during activation of T cells, B cells and macrophages. Biochem Biophys Res Commun 2012, 419:748.
    • (2012) Biochem Biophys Res Commun , vol.419 , pp. 748
    • Li, Y.1    Ohms, S.J.2    Shannon, F.M.3    Sun, C.4    Fan, J.Y.5
  • 69
    • 83355166950 scopus 로고    scopus 로고
    • CAMP-responsive element modulator (CREM)alpha protein signaling mediates epigenetic remodeling of the human interleukin-2 gene: implications in systemic lupus erythematosus
    • Hedrich C.M., Rauen T., Tsokos G.C. cAMP-responsive element modulator (CREM)alpha protein signaling mediates epigenetic remodeling of the human interleukin-2 gene: implications in systemic lupus erythematosus. J Biol Chem 2011, 286:43429-43436.
    • (2011) J Biol Chem , vol.286 , pp. 43429-43436
    • Hedrich, C.M.1    Rauen, T.2    Tsokos, G.C.3
  • 70
    • 67651152585 scopus 로고    scopus 로고
    • T cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus
    • Zhou Y., Yuan J., Pan Y., et al. T cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus. Clin Immunol 2009, 132:362-370.
    • (2009) Clin Immunol , vol.132 , pp. 362-370
    • Zhou, Y.1    Yuan, J.2    Pan, Y.3
  • 71
    • 84864799962 scopus 로고    scopus 로고
    • CD40L demethylation in CD4(+) T cells from women with rheumatoid arthritis
    • Liao J., Liang G., Xie S., et al. CD40L demethylation in CD4(+) T cells from women with rheumatoid arthritis. Clin Immunol 2012, 145:13-18.
    • (2012) Clin Immunol , vol.145 , pp. 13-18
    • Liao, J.1    Liang, G.2    Xie, S.3
  • 72
    • 84858074879 scopus 로고    scopus 로고
    • DNA demethylation of CD40l in CD4+ T cells from women with systemic sclerosis: a possible explanation for female susceptibility
    • Lian X., Xiao R., Hu X., et al. DNA demethylation of CD40l in CD4+ T cells from women with systemic sclerosis: a possible explanation for female susceptibility. Arthritis Rheum 2012, 64:2338-2345.
    • (2012) Arthritis Rheum , vol.64 , pp. 2338-2345
    • Lian, X.1    Xiao, R.2    Hu, X.3
  • 73
    • 38449116161 scopus 로고    scopus 로고
    • Demethylation of CD40LG on the inactive X in T cells from women with lupus
    • Lu Q., Wu A., Tesmer L., Ray D., Yousif N., Richardson B. Demethylation of CD40LG on the inactive X in T cells from women with lupus. J Immunol 2007, 179:6352-6358.
    • (2007) J Immunol , vol.179 , pp. 6352-6358
    • Lu, Q.1    Wu, A.2    Tesmer, L.3    Ray, D.4    Yousif, N.5    Richardson, B.6
  • 74
    • 84155180688 scopus 로고    scopus 로고
    • Immunoglobulin M levels inversely correlate with CD40 ligand promoter methylation in patients with primary biliary cirrhosis
    • Lleo A., Liao J., Invernizzi P., et al. Immunoglobulin M levels inversely correlate with CD40 ligand promoter methylation in patients with primary biliary cirrhosis. Hepatology 2012, 55:153-160.
    • (2012) Hepatology , vol.55 , pp. 153-160
    • Lleo, A.1    Liao, J.2    Invernizzi, P.3
  • 75
    • 27144519226 scopus 로고    scopus 로고
    • An alternative exon 1 of the CD5 gene regulates CD5 expression in human B lymphocytes
    • Renaudineau Y., Hillion S., Saraux A., Mageed R.A., Youinou P. An alternative exon 1 of the CD5 gene regulates CD5 expression in human B lymphocytes. Blood 2005, 106:2781-2789.
    • (2005) Blood , vol.106 , pp. 2781-2789
    • Renaudineau, Y.1    Hillion, S.2    Saraux, A.3    Mageed, R.A.4    Youinou, P.5
  • 76
    • 79955663608 scopus 로고    scopus 로고
    • CD5 expression in B cells from patients with systemic lupus erythematosus
    • Youinou P., Renaudineau Y. CD5 expression in B cells from patients with systemic lupus erythematosus. Crit Rev Immunol 2011, 31:31-42.
    • (2011) Crit Rev Immunol , vol.31 , pp. 31-42
    • Youinou, P.1    Renaudineau, Y.2
  • 77
    • 66949176660 scopus 로고    scopus 로고
    • IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation
    • Garaud S., Le Dantec C., Jousse-Joulin S., et al. IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation. J Immunol 2009, 182:5623-5632.
    • (2009) J Immunol , vol.182 , pp. 5623-5632
    • Garaud, S.1    Le Dantec, C.2    Jousse-Joulin, S.3
  • 78
    • 49649111948 scopus 로고    scopus 로고
    • Selection of the alternative exon 1 from the cd5 gene down-regulates membrane level of the protein in B lymphocytes
    • Garaud S, Le Dantec C, Berthou C, Lydyard PM, Youinou P, Renaudineau Y. Selection of the alternative exon 1 from the cd5 gene down-regulates membrane level of the protein in B lymphocytes. J Immunol. 2008;181:2010-18.
    • (2008) J Immunol. , vol.181 , pp. 2010-18
    • Garaud, S.1    Le Dantec, C.2    Berthou, C.3    Lydyard, P.M.4    Youinou, P.5    Renaudineau, Y.6
  • 79
    • 70350049103 scopus 로고    scopus 로고
    • Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis
    • Lei W., Luo Y., Lei W., et al. Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis. Scand J Rheumatol 2009, 38:369-374.
    • (2009) Scand J Rheumatol , vol.38 , pp. 369-374
    • Lei, W.1    Luo, Y.2    Lei, W.3
  • 80
    • 0025666735 scopus 로고
    • Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis
    • Richardson B., Scheinbart L., Strahler J., Gross L., Hanash S., Johnson M. Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum 1990, 33:1665-1673.
    • (1990) Arthritis Rheum , vol.33 , pp. 1665-1673
    • Richardson, B.1    Scheinbart, L.2    Strahler, J.3    Gross, L.4    Hanash, S.5    Johnson, M.6
  • 81
    • 51349088958 scopus 로고    scopus 로고
    • Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura
    • Tao J., Yang M., Chen Z., et al. Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura. J Clin Immunol 2008, 28:432-439.
    • (2008) J Clin Immunol , vol.28 , pp. 432-439
    • Tao, J.1    Yang, M.2    Chen, Z.3
  • 82
    • 0348149025 scopus 로고    scopus 로고
    • Possible role of DNA hypomethylation in the induction of SLE: relationship to the transcription of human endogenous retroviruses
    • Ogasawara H., Okada M., Kaneko H., Hishikawa T., Sekigawa I., Hashimoto H. Possible role of DNA hypomethylation in the induction of SLE: relationship to the transcription of human endogenous retroviruses. Clin Exp Rheumatol 2003, 21:733-738.
    • (2003) Clin Exp Rheumatol , vol.21 , pp. 733-738
    • Ogasawara, H.1    Okada, M.2    Kaneko, H.3    Hishikawa, T.4    Sekigawa, I.5    Hashimoto, H.6
  • 83
    • 77954548251 scopus 로고    scopus 로고
    • Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus
    • Zhao M, Tang J, Gao F, et al. Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus. J Biomed Biotechnol: 2010:931018.
    • (2010) J Biomed Biotechnol , pp. 931018
    • Zhao, M.1    Tang, J.2    Gao, F.3
  • 84
    • 79957615493 scopus 로고    scopus 로고
    • Hypomethylation of the HTR1A promoter region and high expression of HTR1A in the peripheral blood lymphocytes of patients with systemic lupus erythematosus
    • Xu J., Zhang G., Cheng Y., et al. Hypomethylation of the HTR1A promoter region and high expression of HTR1A in the peripheral blood lymphocytes of patients with systemic lupus erythematosus. Lupus 2011, 20:678-689.
    • (2011) Lupus , vol.20 , pp. 678-689
    • Xu, J.1    Zhang, G.2    Cheng, Y.3
  • 85
    • 79955048011 scopus 로고    scopus 로고
    • Promoter hypomethylation results in increased expression of protein phosphatase 2A in T cells from patients with systemic lupus erythematosus
    • Sunahori K., Juang Y.T., Kyttaris V.C., Tsokos G.C. Promoter hypomethylation results in increased expression of protein phosphatase 2A in T cells from patients with systemic lupus erythematosus. J Immunol 2011, 186:4508-4517.
    • (2011) J Immunol , vol.186 , pp. 4508-4517
    • Sunahori, K.1    Juang, Y.T.2    Kyttaris, V.C.3    Tsokos, G.C.4
  • 86
    • 75649151209 scopus 로고    scopus 로고
    • Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
    • Javierre B.M., Fernandez A.F., Richter J., et al. Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res 2010, 20:170-179.
    • (2010) Genome Res , vol.20 , pp. 170-179
    • Javierre, B.M.1    Fernandez, A.F.2    Richter, J.3
  • 87
    • 70349260307 scopus 로고    scopus 로고
    • Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells
    • Basu D., Liu Y., Wu A., et al. Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells. J Immunol 2009, 183:3481-3487.
    • (2009) J Immunol , vol.183 , pp. 3481-3487
    • Basu, D.1    Liu, Y.2    Wu, A.3
  • 88
    • 77951745847 scopus 로고    scopus 로고
    • Overexpression of the growth arrest and DNA damage-induced 45alpha gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells
    • Li Y., Zhao M., Yin H., et al. Overexpression of the growth arrest and DNA damage-induced 45alpha gene contributes to autoimmunity by promoting DNA demethylation in lupus T cells. Arthritis Rheum 2010, 62:1438-1447.
    • (2010) Arthritis Rheum , vol.62 , pp. 1438-1447
    • Li, Y.1    Zhao, M.2    Yin, H.3
  • 89
    • 79957550675 scopus 로고    scopus 로고
    • Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus
    • Jeffries M.A., Dozmorov M., Tang Y., Merrill J.T., Wren J.D., Sawalha A.H., Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus. Epigenetics 2011, 6:593-601.
    • (2011) Epigenetics , vol.6 , pp. 593-601
    • Jeffries, M.A.1    Dozmorov, M.2    Tang, Y.3    Merrill, J.T.4    Wren, J.D.5    Sawalha, A.H.6
  • 90
    • 78751703609 scopus 로고    scopus 로고
    • Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis
    • Liu C.C., Fang T.J., Ou T.T., et al. Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis. Immunol Lett 2011, 135:96-99.
    • (2011) Immunol Lett , vol.135 , pp. 96-99
    • Liu, C.C.1    Fang, T.J.2    Ou, T.T.3
  • 91
    • 82555192432 scopus 로고    scopus 로고
    • DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts
    • Karouzakis E., Rengel Y., Jungel A., et al. DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts. Genes Immun 2011, 12:643-652.
    • (2011) Genes Immun , vol.12 , pp. 643-652
    • Karouzakis, E.1    Rengel, Y.2    Jungel, A.3
  • 92
    • 65849304544 scopus 로고    scopus 로고
    • Methylation status of the IL-10 gene promoter in the peripheral blood mononuclear cells of rheumatoid arthritis patients
    • Fu L.H., Cong B., Zhen Y.F., et al. Methylation status of the IL-10 gene promoter in the peripheral blood mononuclear cells of rheumatoid arthritis patients. Yi Chuan 2007, 29:1357-1361.
    • (2007) Yi Chuan , vol.29 , pp. 1357-1361
    • Fu, L.H.1    Cong, B.2    Zhen, Y.F.3
  • 93
    • 33644890154 scopus 로고    scopus 로고
    • Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells
    • Takami N., Osawa K., Miura Y., et al. Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells. Arthritis Rheum 2006, 54:779-787.
    • (2006) Arthritis Rheum , vol.54 , pp. 779-787
    • Takami, N.1    Osawa, K.2    Miura, Y.3
  • 94
    • 84861454178 scopus 로고    scopus 로고
    • The characteristics of genome-wide DNA methylation in naive CD4+ T cells of patients with psoriasis or atopic dermatitis
    • Han J., Park S.G., Bae J.B., et al. The characteristics of genome-wide DNA methylation in naive CD4+ T cells of patients with psoriasis or atopic dermatitis. Biochem Biophys Res Commun 2012, 422:157-163.
    • (2012) Biochem Biophys Res Commun , vol.422 , pp. 157-163
    • Han, J.1    Park, S.G.2    Bae, J.B.3
  • 95
    • 77957020785 scopus 로고    scopus 로고
    • Abnormal DNA methylation in skin lesions and PBMCs of patients with psoriasis vulgaris
    • Zhang P., Su Y., Chen H., Zhao M., Lu Q. Abnormal DNA methylation in skin lesions and PBMCs of patients with psoriasis vulgaris. J Dermatol Sci 2010, 60:40-42.
    • (2010) J Dermatol Sci , vol.60 , pp. 40-42
    • Zhang, P.1    Su, Y.2    Chen, H.3    Zhao, M.4    Lu, Q.5
  • 96
    • 65449156487 scopus 로고    scopus 로고
    • Promoter methylation status of p15 and p21 genes in HPP-CFCs of bone marrow of patients with psoriasis
    • Zhang K., Zhang R., Li X., Yin G., Niu X. Promoter methylation status of p15 and p21 genes in HPP-CFCs of bone marrow of patients with psoriasis. Eur J Dermatol 2009, 19:141-146.
    • (2009) Eur J Dermatol , vol.19 , pp. 141-146
    • Zhang, K.1    Zhang, R.2    Li, X.3    Yin, G.4    Niu, X.5
  • 97
    • 35349021500 scopus 로고    scopus 로고
    • The mRNA expression and promoter methylation status of the p16 gene in colony-forming cells with high proliferative potential in patients with psoriasis
    • Zhang K., Zhang R., Li X., Yin G., Niu X., Hou R. The mRNA expression and promoter methylation status of the p16 gene in colony-forming cells with high proliferative potential in patients with psoriasis. Clin Exp Dermatol 2007, 32:702-708.
    • (2007) Clin Exp Dermatol , vol.32 , pp. 702-708
    • Zhang, K.1    Zhang, R.2    Li, X.3    Yin, G.4    Niu, X.5    Hou, R.6
  • 99
    • 42049105569 scopus 로고    scopus 로고
    • The methylation pattern of p16INK4a gene promoter in psoriatic epidermis and its clinical significance
    • Chen M., Chen Z.Q., Cui P.G., et al. The methylation pattern of p16INK4a gene promoter in psoriatic epidermis and its clinical significance. Br J Dermatol 2008, 158:987-993.
    • (2008) Br J Dermatol , vol.158 , pp. 987-993
    • Chen, M.1    Chen, Z.Q.2    Cui, P.G.3
  • 100
    • 34447334574 scopus 로고    scopus 로고
    • Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated
    • Mastronardi F.G., Noor A., Wood D.D., Paton T., Moscarello M.A. Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated. J Neurosci Res 2007, 85:2006-2016.
    • (2007) J Neurosci Res , vol.85 , pp. 2006-2016
    • Mastronardi, F.G.1    Noor, A.2    Wood, D.D.3    Paton, T.4    Moscarello, M.A.5
  • 101
    • 84860203756 scopus 로고    scopus 로고
    • Increased promoter methylation of the immune regulatory gene SHP-1 in leukocytes of multiple sclerosis subjects
    • Kumagai C., Kalman B., Middleton F.A., Vyshkina T., Massa P.T. Increased promoter methylation of the immune regulatory gene SHP-1 in leukocytes of multiple sclerosis subjects. J Neuroimmunol 2012, 246:51-57.
    • (2012) J Neuroimmunol , vol.246 , pp. 51-57
    • Kumagai, C.1    Kalman, B.2    Middleton, F.A.3    Vyshkina, T.4    Massa, P.T.5
  • 102
    • 84857805315 scopus 로고    scopus 로고
    • Methylation-dependent PAD2 upregulation in multiple sclerosis peripheral blood
    • Calabrese R., Zampieri M., Mechelli R., et al. Methylation-dependent PAD2 upregulation in multiple sclerosis peripheral blood. Mult Scler 2012, 18:299-304.
    • (2012) Mult Scler , vol.18 , pp. 299-304
    • Calabrese, R.1    Zampieri, M.2    Mechelli, R.3
  • 103
    • 84858080226 scopus 로고    scopus 로고
    • Epigenetic patterns in systemic sclerosis and their contribution to attenuated CD70 signaling cascades
    • Hedrich C.M., Rauen T. Epigenetic patterns in systemic sclerosis and their contribution to attenuated CD70 signaling cascades. Clin Immunol 2012, 143:1-3.
    • (2012) Clin Immunol , vol.143 , pp. 1-3
    • Hedrich, C.M.1    Rauen, T.2
  • 104
    • 84860485825 scopus 로고    scopus 로고
    • Association of the CpG methylation pattern of the proximal insulin gene promoter with type 1 diabetes
    • Fradin D., Le Fur S., Mille C., et al. Association of the CpG methylation pattern of the proximal insulin gene promoter with type 1 diabetes. PLoS One 2012, 7:e36278.
    • (2012) PLoS One , vol.7
    • Fradin, D.1    Le Fur, S.2    Mille, C.3
  • 105
    • 80051539323 scopus 로고    scopus 로고
    • DNA methylation of colon mucosa in ulcerative colitis patients: correlation with inflammatory status
    • Saito S., Kato J., Hiraoka S., et al. DNA methylation of colon mucosa in ulcerative colitis patients: correlation with inflammatory status. Inflamm Bowel Dis 2011, 17:1955-1965.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1955-1965
    • Saito, S.1    Kato, J.2    Hiraoka, S.3
  • 106
    • 67649451991 scopus 로고    scopus 로고
    • Effect of MDR1 gene promoter methylation in patients with ulcerative colitis
    • Tahara T., Shibata T., Nakamura M., et al. Effect of MDR1 gene promoter methylation in patients with ulcerative colitis. Int J Mol Med 2009, 23:521-527.
    • (2009) Int J Mol Med , vol.23 , pp. 521-527
    • Tahara, T.1    Shibata, T.2    Nakamura, M.3
  • 107
    • 0032148387 scopus 로고    scopus 로고
    • Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis
    • Hsieh C.J., Klump B., Holzmann K., Borchard F., Gregor M., Porschen R. Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis. Cancer Res 1998, 58:3942-3945.
    • (1998) Cancer Res , vol.58 , pp. 3942-3945
    • Hsieh, C.J.1    Klump, B.2    Holzmann, K.3    Borchard, F.4    Gregor, M.5    Porschen, R.6
  • 108
    • 34748900060 scopus 로고    scopus 로고
    • Hypermethylation of p14 (ARF) may be predictive of colitic cancer in patients with ulcerative colitis
    • Moriyama T., Matsumoto T., Nakamura S., et al. Hypermethylation of p14 (ARF) may be predictive of colitic cancer in patients with ulcerative colitis. Dis Colon Rectum 2007, 50:1384-1392.
    • (2007) Dis Colon Rectum , vol.50 , pp. 1384-1392
    • Moriyama, T.1    Matsumoto, T.2    Nakamura, S.3
  • 109
    • 77954663598 scopus 로고    scopus 로고
    • DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with ulcerative colitis (UC)
    • Arasaradnam R.P., Khoo K., Bradburn M., Mathers J.C., Kelly S.B. DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with ulcerative colitis (UC). Epigenetics 2010, 5:422-426.
    • (2010) Epigenetics , vol.5 , pp. 422-426
    • Arasaradnam, R.P.1    Khoo, K.2    Bradburn, M.3    Mathers, J.C.4    Kelly, S.B.5
  • 110
    • 67349285075 scopus 로고    scopus 로고
    • Promoter methylation of protease-activated receptor (PAR2) is associated with severe clinical phenotypes of ulcerative colitis (UC)
    • Tahara T., Shibata T., Nakamura M., et al. Promoter methylation of protease-activated receptor (PAR2) is associated with severe clinical phenotypes of ulcerative colitis (UC). Clin Exp Med 2009, 9:125-130.
    • (2009) Clin Exp Med , vol.9 , pp. 125-130
    • Tahara, T.1    Shibata, T.2    Nakamura, M.3
  • 111
    • 79952188432 scopus 로고    scopus 로고
    • Thrombopoietic growth factors in the treatment of immune thrombocytopenic purpura
    • Wang T., Wang Z., Yang R. Thrombopoietic growth factors in the treatment of immune thrombocytopenic purpura. Crit Rev Oncol Hematol 2011, 77:172-183.
    • (2011) Crit Rev Oncol Hematol , vol.77 , pp. 172-183
    • Wang, T.1    Wang, Z.2    Yang, R.3
  • 112
    • 1642320808 scopus 로고    scopus 로고
    • Adult chronic idiopathic thrombocytopenic purpura (ITP) is the manifestation of a type-1 polarized immune response
    • Panitsas F.P., Theodoropoulou M., Kouraklis A., et al. Adult chronic idiopathic thrombocytopenic purpura (ITP) is the manifestation of a type-1 polarized immune response. Blood 2004, 103:2645-2647.
    • (2004) Blood , vol.103 , pp. 2645-2647
    • Panitsas, F.P.1    Theodoropoulou, M.2    Kouraklis, A.3
  • 113
    • 0029964421 scopus 로고    scopus 로고
    • Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity
    • Semple J.W., Milev Y., Cosgrave D., et al. Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity. Blood 1996, 87:4245-4254.
    • (1996) Blood , vol.87 , pp. 4245-4254
    • Semple, J.W.1    Milev, Y.2    Cosgrave, D.3
  • 114
    • 0141684568 scopus 로고    scopus 로고
    • T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura
    • Olsson B., Andersson P.O., Jernas M., et al. T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura. Nat Med 2003, 9:1123-1124.
    • (2003) Nat Med , vol.9 , pp. 1123-1124
    • Olsson, B.1    Andersson, P.O.2    Jernas, M.3
  • 115
    • 78049291385 scopus 로고    scopus 로고
    • Recent progress in understanding the pathogenesis of immune thrombocytopenia
    • Semple J.W., Provan D., Garvey M.B., Freedman J. Recent progress in understanding the pathogenesis of immune thrombocytopenia. Curr Opin Hematol 2010, 17:590-595.
    • (2010) Curr Opin Hematol , vol.17 , pp. 590-595
    • Semple, J.W.1    Provan, D.2    Garvey, M.B.3    Freedman, J.4
  • 116
    • 0017717784 scopus 로고
    • Platelet-bound complement (C3) in immune thrombocytopenia
    • Hauch T.W., Rosse W.F. Platelet-bound complement (C3) in immune thrombocytopenia. Blood 1977, 50:1129-1136.
    • (1977) Blood , vol.50 , pp. 1129-1136
    • Hauch, T.W.1    Rosse, W.F.2
  • 117
    • 0033981770 scopus 로고    scopus 로고
    • Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrations
    • Melnyk S., Pogribna M., Pogribny I.P., Yi P., James S.J. Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrations. Clin Chem 2000, 46:265-272.
    • (2000) Clin Chem , vol.46 , pp. 265-272
    • Melnyk, S.1    Pogribna, M.2    Pogribny, I.P.3    Yi, P.4    James, S.J.5
  • 119
    • 84862835989 scopus 로고    scopus 로고
    • Role of DNA methyltransferase 3A mRNA expression in Egyptian patients with idiopathic thrombocytopenic purpura
    • El-Shiekh E.H., Bessa S.S., Abdou S.M., El-Refaey W.A. Role of DNA methyltransferase 3A mRNA expression in Egyptian patients with idiopathic thrombocytopenic purpura. Int J Lab Hematol 2012, 34:369-376.
    • (2012) Int J Lab Hematol , vol.34 , pp. 369-376
    • El-Shiekh, E.H.1    Bessa, S.S.2    Abdou, S.M.3    El-Refaey, W.A.4
  • 120
    • 0018378083 scopus 로고
    • Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions
    • Hoffman D.R., Cornatzer W.E., Duerre J.A. Relationship between tissue levels of S-adenosylmethionine, S-adenylhomocysteine, and transmethylation reactions. Can J Biochem 1979, 57:56-65.
    • (1979) Can J Biochem , vol.57 , pp. 56-65
    • Hoffman, D.R.1    Cornatzer, W.E.2    Duerre, J.A.3
  • 121
    • 79955782511 scopus 로고    scopus 로고
    • Decreased expression of MBD2 and MBD4 gene and genomic-wide hypomethylation in patients with primary immune thrombocytopenia
    • Chen Z.P., Gu D.S., Zhou Z.P., et al. Decreased expression of MBD2 and MBD4 gene and genomic-wide hypomethylation in patients with primary immune thrombocytopenia. Hum Immunol 2011, 72:486-491.
    • (2011) Hum Immunol , vol.72 , pp. 486-491
    • Chen, Z.P.1    Gu, D.S.2    Zhou, Z.P.3
  • 122
    • 27144534809 scopus 로고    scopus 로고
    • Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity
    • Hutchins A.S., Artis D., Hendrich B.D., Bird A.P., Scott P., Reiner S.L. Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. J Immunol 2005, 175:5606-5610.
    • (2005) J Immunol , vol.175 , pp. 5606-5610
    • Hutchins, A.S.1    Artis, D.2    Hendrich, B.D.3    Bird, A.P.4    Scott, P.5    Reiner, S.L.6
  • 123
    • 80555155586 scopus 로고    scopus 로고
    • Effects of CD70 and CD11a in immune thrombocytopenia patients
    • Ma L., Zhou Z., Jia H., et al. Effects of CD70 and CD11a in immune thrombocytopenia patients. J Clin Immunol 2011, 31:632-642.
    • (2011) J Clin Immunol , vol.31 , pp. 632-642
    • Ma, L.1    Zhou, Z.2    Jia, H.3
  • 124
    • 77149127692 scopus 로고    scopus 로고
    • The expression of IFN-gamma, IL-4, Foxp3 and perforin genes are not correlated with DNA methylation status in patients with immune thrombocytopenic purpura
    • Zhao H., Du W., Wang D., et al. The expression of IFN-gamma, IL-4, Foxp3 and perforin genes are not correlated with DNA methylation status in patients with immune thrombocytopenic purpura. Platelets 2012, 21:137-143.
    • (2012) Platelets , vol.21 , pp. 137-143
    • Zhao, H.1    Du, W.2    Wang, D.3
  • 125
    • 51349090553 scopus 로고    scopus 로고
    • Single nucleotide polymorphism in DNMT3B promoter and the risk for idiopathic thrombocytopenic purpura in Chinese population
    • Chen Z., Zhou Z., Chen X., et al. Single nucleotide polymorphism in DNMT3B promoter and the risk for idiopathic thrombocytopenic purpura in Chinese population. J Clin Immunol 2008, 28:399-404.
    • (2008) J Clin Immunol , vol.28 , pp. 399-404
    • Chen, Z.1    Zhou, Z.2    Chen, X.3
  • 126
    • 84866992762 scopus 로고    scopus 로고
    • DNMT3B promoter polymorphism and risk of immune thrombocytopenic purpura in pediatric Egyptians
    • Shaheen I.A., Abukhalil R.E., Ali D.K., Afifi R.A. DNMT3B promoter polymorphism and risk of immune thrombocytopenic purpura in pediatric Egyptians. Blood Coagul Fibrinolysis 2012, 23:636-639.
    • (2012) Blood Coagul Fibrinolysis , vol.23 , pp. 636-639
    • Shaheen, I.A.1    Abukhalil, R.E.2    Ali, D.K.3    Afifi, R.A.4
  • 127
    • 68949128784 scopus 로고    scopus 로고
    • DNMT3B 579G>T promoter polymorphism and the risk for idiopathic thrombocytopenic purpura in a Chinese population
    • Zhao H., Du W., Gu D., et al. DNMT3B 579G>T promoter polymorphism and the risk for idiopathic thrombocytopenic purpura in a Chinese population. Acta Haematol 2009, 122:31-35.
    • (2009) Acta Haematol , vol.122 , pp. 31-35
    • Zhao, H.1    Du, W.2    Gu, D.3
  • 128
    • 0033575886 scopus 로고    scopus 로고
    • The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
    • Hendrich B., Hardeland U., Ng H.H., Jiricny J., Bird A. The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature 1999, 401:301-304.
    • (1999) Nature , vol.401 , pp. 301-304
    • Hendrich, B.1    Hardeland, U.2    Ng, H.H.3    Jiricny, J.4    Bird, A.5
  • 129
    • 77149180399 scopus 로고    scopus 로고
    • Single nucleotide polymorphism in the methyl-CpG binding domain 4 gene and the risk for immune thrombocytopenic purpura in Chinese population
    • Zhao H., Du W., Wang D., et al. Single nucleotide polymorphism in the methyl-CpG binding domain 4 gene and the risk for immune thrombocytopenic purpura in Chinese population. Platelets 2010, 21:132-136.
    • (2010) Platelets , vol.21 , pp. 132-136
    • Zhao, H.1    Du, W.2    Wang, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.