메뉴 건너뛰기




Volumn 41, Issue 8, 2013, Pages 4535-4548

Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; GENOMIC DNA; RAG1 PROTEIN; RAG2 PROTEIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN;

EID: 84877294284     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt154     Document Type: Article
Times cited : (18)

References (45)
  • 1
    • 80355122714 scopus 로고    scopus 로고
    • V(D) J recombination: Mechanisms of initiation
    • Schatz, D.G. and Swanson, P.C. (2011) V(D)J recombination: mechanisms of initiation. Annu. Rev. Genet., 45, 167-202.
    • (2011) Annu. Rev. Genet , vol.45 , pp. 167-202
    • Schatz, D.G.1    Swanson, P.C.2
  • 2
    • 0032084698 scopus 로고    scopus 로고
    • Assembly of a 12/23 paired signal complex: A critical control point in V(D)
    • Hiom, K. and Gellert, M. (1998) Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination. Mol. Cell, 1, 1011-1019.
    • (1998) J Recombination. Mol. Cell , vol.1 , pp. 1011-1019
    • Hiom, K.1    Gellert, M.2
  • 3
    • 0030009253 scopus 로고    scopus 로고
    • The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)
    • van Gent, D.C., Ramsden, D.A. and Gellert, M. (1996) The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination. Cell, 85, 107-113.
    • (1996) J Recombination. Cell , vol.85 , pp. 107-113
    • Van Gent, D.C.1    Ramsden, D.A.2    Gellert, M.3
  • 4
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. (1983) Somatic generation of antibody diversity. Nature, 302, 575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 5
    • 0033104727 scopus 로고    scopus 로고
    • Characterization of TCR gene rearrangements during adult murine T cell development
    • Livak, F., Tourigny, M., Schatz, D.G. and Petrie, H.T. (1999) Characterization of TCR gene rearrangements during adult murine T cell development. J. Immunol., 162, 2575-2580.
    • (1999) J. Immunol , vol.162 , pp. 2575-2580
    • Livak, F.1    Tourigny, M.2    Schatz, D.G.3    Petrie, H.T.4
  • 6
    • 0030051855 scopus 로고    scopus 로고
    • Leukemia and lymphoma in ataxia telangiectasia
    • Taylor, A.M., Metcalfe, J.A., Thick, J. and Mak, Y.F. (1996) Leukemia and lymphoma in ataxia telangiectasia. Blood, 87, 423-438.
    • (1996) Blood , vol.87 , pp. 423-438
    • Taylor, A.M.1    Metcalfe, J.A.2    Thick, J.3    Mak, Y.F.4
  • 8
    • 0034284341 scopus 로고    scopus 로고
    • Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice
    • Liyanage, M., Weaver, Z., Barlow, C., Coleman, A., Pankratz, D.G., Anderson, S., Wynshaw-Boris, A. and Ried, T. (2000) Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice. Blood, 96, 1940-1946.
    • (2000) Blood , vol.96 , pp. 1940-1946
    • Liyanage, M.1    Weaver, Z.2    Barlow, C.3    Coleman, A.4    Pankratz, D.G.5    Anderson, S.6    Wynshaw-Boris, A.7    Ried, T.8
  • 9
    • 0018832231 scopus 로고
    • High frequencies of inversions and translocations of chromosomes 7 and 14 in ataxia telangiectasia
    • Aurias, A., Dutrillaux, B., Buriot, D. and Lejeune, J. (1980) High frequencies of inversions and translocations of chromosomes 7 and 14 in ataxia telangiectasia. Mutat. Res., 69, 369-374.
    • (1980) Mutat. Res , vol.69 , pp. 369-374
    • Aurias, A.1    Dutrillaux, B.2    Buriot, D.3    Lejeune, J.4
  • 10
    • 0025954329 scopus 로고
    • Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia
    • Kobayashi, Y., Tycko, B., Soreng, A.L. and Sklar, J. (1991) Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia. J. Immunol., 147, 3201-3209.
    • (1991) J. Immunol , vol.147 , pp. 3201-3209
    • Kobayashi, Y.1    Tycko, B.2    Soreng, A.L.3    Sklar, J.4
  • 11
    • 0024987973 scopus 로고
    • Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes
    • Lipkowitz, S., Stern, M.H. and Kirsch, I.R. (1990) Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes. J. Exp. Med., 172, 409-418.
    • (1990) J. Exp. Med , vol.172 , pp. 409-418
    • Lipkowitz, S.1    Stern, M.H.2    Kirsch, I.R.3
  • 12
    • 0024452767 scopus 로고
    • Inversion of chromosome 7 in ataxia telangiectasia is generated by a rearrangement between T-cell receptor beta and T-cell receptor gamma genes
    • Stern, M.H., Lipkowitz, S., Aurias, A., Griscelli, C., Thomas, G. and Kirsch, I.R. (1989) Inversion of chromosome 7 in ataxia telangiectasia is generated by a rearrangement between T-cell receptor beta and T-cell receptor gamma genes. Blood, 74, 2076-2080.
    • (1989) Blood , vol.74 , pp. 2076-2080
    • Stern, M.H.1    Lipkowitz, S.2    Aurias, A.3    Griscelli, C.4    Thomas, G.5    Kirsch, I.R.6
  • 15
    • 33645072212 scopus 로고    scopus 로고
    • ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: The DSB connection
    • Matei, I.R., Guidos, C.J. and Danska, J.S. (2006) ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection. Immunol. Rev., 209, 142-158.
    • (2006) Immunol. Rev , vol.209 , pp. 142-158
    • Matei, I.R.1    Guidos, C.J.2    Danska, J.S.3
  • 18
    • 0026604579 scopus 로고
    • Simultaneous visualization of seven different DNA probes by in situ hybridization using combinatorial fluorescence and digital imaging microscopy
    • Ried, T., Baldini, A., Rand, T.C. and Ward, D.C. (1992) Simultaneous visualization of seven different DNA probes by in situ hybridization using combinatorial fluorescence and digital imaging microscopy. Proc. Natl Acad. Sci. USA, 89, 1388-1392.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 1388-1392
    • Ried, T.1    Baldini, A.2    Rand, T.C.3    Ward, D.C.4
  • 21
    • 13244275244 scopus 로고    scopus 로고
    • Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells
    • Sayegh, C.E., Jhunjhunwala, S., Riblet, R. and Murre, C. (2005) Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells. Genes Dev., 19, 322-327.
    • (2005) Genes Dev , vol.19 , pp. 322-327
    • Sayegh, C.E.1    Jhunjhunwala, S.2    Riblet, R.3    Murre, C.4
  • 23
    • 0034739853 scopus 로고    scopus 로고
    • P53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • Schultz, L.B., Chehab, N.H., Malikzay, A. and Halazonetis, T.D. (2000) p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol., 151, 1381-1390.
    • (2000) J. Cell Biol , vol.151 , pp. 1381-1390
    • Schultz, L.B.1    Chehab, N.H.2    Malikzay, A.3    Halazonetis, T.D.4
  • 24
    • 34250374139 scopus 로고    scopus 로고
    • Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes
    • Huang, C.Y., Sharma, G.G., Walker, L.M., Bassing, C.H., Pandita, T.K. and Sleckman, B.P. (2007) Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes. J. Exp. Med., 204, 1371-1381.
    • (2007) J. Exp. Med , vol.204 , pp. 1371-1381
    • Huang, C.Y.1    Sharma, G.G.2    Walker, L.M.3    Bassing, C.H.4    Pandita, T.K.5    Sleckman, B.P.6
  • 25
    • 9744220428 scopus 로고    scopus 로고
    • A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci
    • Riballo, E., Kuhne, M., Rief, N., Doherty, A., Smith, G.C., Recio, M.J., Reis, C., Dahm, K., Fricke, A., Krempler, A. et al. (2004) A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol. Cell, 16, 715-724.
    • (2004) Mol. Cell , vol.16 , pp. 715-724
    • Riballo, E.1    Kuhne, M.2    Rief, N.3    Doherty, A.4    Smith, G.C.5    Recio, M.J.6    Reis, C.7    Dahm, K.8    Fricke, A.9    Krempler, A.10
  • 27
    • 33845986339 scopus 로고    scopus 로고
    • Spatial genome organization in the formation of chromosomal translocations
    • Meaburn, K.J., Misteli, T. and Soutoglou, E. (2007) Spatial genome organization in the formation of chromosomal translocations. Semin. Cancer Biol., 17, 80-90.
    • (2007) Semin. Cancer Biol , vol.17 , pp. 80-90
    • Meaburn, K.J.1    Misteli, T.2    Soutoglou, E.3
  • 28
    • 0038054340 scopus 로고    scopus 로고
    • Spatial proximity of translocation-prone gene loci in human lymphomas
    • Roix, J.J., McQueen, P.G., Munson, P.J., Parada, L.A. and Misteli, T. (2003) Spatial proximity of translocation-prone gene loci in human lymphomas. Nat. Genet., 34, 287-291.
    • (2003) Nat. Genet , vol.34 , pp. 287-291
    • Roix, J.J.1    McQueen, P.G.2    Munson, P.J.3    Parada, L.A.4    Misteli, T.5
  • 29
    • 18644381771 scopus 로고    scopus 로고
    • Beyond the 12/23 rule of VDJ recombination independent of the Rag proteins
    • Olaru, A., Petrie, H.T. and Livak, F. (2005) Beyond the 12/23 rule of VDJ recombination independent of the Rag proteins. J. Immunol., 174, 6220-6226.
    • (2005) J. Immunol , vol.174 , pp. 6220-6226
    • Olaru, A.1    Petrie, H.T.2    Livak, F.3
  • 31
    • 78649707827 scopus 로고    scopus 로고
    • ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks
    • Bennardo, N. and Stark, J.M. (2010) ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks. PLoS Genet., 6, e1001194.
    • (2010) PLoS Genet , vol.6
    • Bennardo, N.1    Stark, J.M.2
  • 33
    • 67349209606 scopus 로고    scopus 로고
    • Violations of the 12/23 rule at the mouse immunoglobulin kappa locus including v kappa-V kappa rearrangement
    • Vinocur, J.M., Fesnak, A.D., Liu, Y., Charan, D. and Prak, E.T. (2009) Violations of the 12/23 rule at the mouse immunoglobulin kappa locus, including V kappa-V kappa rearrangement. Mol. Immunol., 46, 2183-2189.
    • (2009) Mol. Immunol , vol.46 , pp. 2183-2189
    • Vinocur, J.M.1    Fesnak, A.D.2    Liu, Y.3    Charan, D.4    Prak, E.T.5
  • 35
    • 0026683328 scopus 로고
    • Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies
    • Lipkowitz, S., Garry, V.F. and Kirsch, I.R. (1992) Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies. Proc. Natl Acad. Sci. USA, 89, 5301-5305.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 5301-5305
    • Lipkowitz, S.1    Garry, V.F.2    Kirsch, I.R.3
  • 36
    • 0030874643 scopus 로고    scopus 로고
    • The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: A severe combined immune deficiency (SCID) murine model
    • Lista, F., Bertness, V., Guidos, C.J., Danska, J.S. and Kirsch, I.R. (1997) The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: a severe combined immune deficiency (SCID) murine model. Cancer Res., 57, 4408-4413.
    • (1997) Cancer Res , vol.57 , pp. 4408-4413
    • Lista, F.1    Bertness, V.2    Guidos, C.J.3    Danska, J.S.4    Kirsch, I.R.5
  • 37
    • 0022518317 scopus 로고
    • A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci
    • Denny, C.T., Yoshikai, Y., Mak, T.W., Smith, S.D., Hollis, G.F. and Kirsch, I.R. (1986) A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci. Nature, 320, 549-551.
    • (1986) Nature , vol.320 , pp. 549-551
    • Denny, C.T.1    Yoshikai, Y.2    Mak, T.W.3    Smith, S.D.4    Hollis, G.F.5    Kirsch, I.R.6
  • 38
    • 57349185631 scopus 로고    scopus 로고
    • Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity
    • Tsai, A.G., Lu, H., Raghavan, S.C., Muschen, M., Hsieh, C.L. and Lieber, M.R. (2008) Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell, 135, 1130-1142.
    • (2008) Cell , vol.135 , pp. 1130-1142
    • Tsai, A.G.1    Lu, H.2    Raghavan, S.C.3    Muschen, M.4    Hsieh, C.L.5    Lieber, M.R.6
  • 39
    • 0036709614 scopus 로고    scopus 로고
    • Chromosome positioning in the interphase nucleus
    • Parada, L. and Misteli, T. (2002) Chromosome positioning in the interphase nucleus. Trends Cell Biol., 12, 425-432.
    • (2002) Trends Cell Biol , vol.12 , pp. 425-432
    • Parada, L.1    Misteli, T.2
  • 40
    • 52149111656 scopus 로고    scopus 로고
    • On the contribution of spatial genome organization to cancerous chromosome translocations
    • Soutoglou, E. and Misteli, T. (2008) On the contribution of spatial genome organization to cancerous chromosome translocations. J. Natl Cancer Inst. Monogr., 39, 16-19.
    • (2008) J. Natl Cancer Inst. Monogr , vol.39 , pp. 16-19
    • Soutoglou, E.1    Misteli, T.2
  • 41
    • 34447106461 scopus 로고    scopus 로고
    • ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor alpha locus coding end breaks
    • Vacchio, M.S., Olaru, A., Livak, F. and Hodes, R.J. (2007) ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor alpha locus coding end breaks. Proc. Natl Acad. Sci. USA, 104, 6323-6328.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 6323-6328
    • Vacchio, M.S.1    Olaru, A.2    Livak, F.3    Hodes, R.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.