-
1
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou BB, Elledge SJ (2000) The DNA damage response: Putting checkpoints in perspective. Nature 408:433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
2
-
-
0035093737
-
DNA double-strand breaks: Signaling, repair and the cancer connection
-
DOI 10.1038/85798
-
Khanna KK, Jackson SP (2001) DNA double-strand breaks: Signaling, repair, and the cancer connection. Nat Genet 27:247-254. (Pubitemid 32201842)
-
(2001)
Nature Genetics
, vol.27
, Issue.3
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
3
-
-
34249794280
-
Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism
-
DOI 10.1016/S0065-2776(06)94006-1, PII S0065277606940061, AID for Immunoglobulin Diversity
-
Chaudhuri J, et al. (2007) Evolution of the immunoglobulin heavy chain class switch recombination mechanism. Adv Immunol 94:157-214. (Pubitemid 46856611)
-
(2007)
Advances in Immunology
, vol.94
, pp. 157-214
-
-
Chaudhuri, J.1
Basu, U.2
Zarrin, A.3
Yan, C.4
Franco, S.5
Perlot, T.6
Vuong, B.7
Wang, J.8
Phan, R.T.9
Datta, A.10
Manis, J.11
Alt, F.W.12
-
4
-
-
0036240127
-
The mechanism and regulation of chromosomal V(D)J recombination
-
DOI 10.1016/S0092-8674(02)00675-X
-
Bassing CH, Swat W, Alt FW (2002) The mechanism and regulation of chromosomal V(D)J recombination. Cell 109(Suppl):S45-S55. (Pubitemid 34457851)
-
(2002)
Cell
, vol.109
, Issue.2 SUPPL. 1
-
-
Bassing, C.H.1
Swat, W.2
Alt, F.W.3
-
5
-
-
0034094425
-
The RAG proteins and V(D)J recombination: Complexes, ends, and transposition
-
Fugmann SD, Lee AI, Shockett PE, Villey IJ, Schatz DG (2000) The RAG proteins and V(D)J recombination: Complexes, ends, and transposition. Annu Rev Immunol 18:495-527.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 495-527
-
-
Fugmann, S.D.1
Lee, A.I.2
Shockett, P.E.3
Villey, I.J.4
Schatz, D.G.5
-
7
-
-
0035839959
-
Mechanisms of chromosomal translocations in B cell lymphomas
-
DOI 10.1038/sj.onc.1204640
-
Kuppers R, Dalla-Favera R (2001) Mechanisms of chromosomal translocations in B cell lymphomas. Oncogene 20:5580-5594. (Pubitemid 32928099)
-
(2001)
Oncogene
, vol.20
, Issue.40 REV. ISS. 4
, pp. 5580-5594
-
-
Kuppers, R.1
Dalla-Favera, R.2
-
8
-
-
33745121244
-
Leukemia and lymphoma: A cost of doing business for adaptive immunity
-
Schlissel MS, Kaffer CR, Curry JD (2006) Leukemia and lymphoma: A cost of doing business for adaptive immunity. Genes Dev 20:1539-1544.
-
(2006)
Genes Dev
, vol.20
, pp. 1539-1544
-
-
Schlissel, M.S.1
Kaffer, C.R.2
Curry, J.D.3
-
9
-
-
57149141010
-
Collateral damage from antigen receptor gene diversification
-
Mahowald GK, Baron JM, Sleckman BP (2008) Collateral damage from antigen receptor gene diversification. Cell 135:1009-1012.
-
(2008)
Cell
, vol.135
, pp. 1009-1012
-
-
Mahowald, G.K.1
Baron, J.M.2
Sleckman, B.P.3
-
10
-
-
34547589577
-
Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70
-
DOI 10.1038/ncb1623, PII NCB1624
-
Weinstock DM, Brunet E, Jasin M (2007) Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70. Nat Cell Biol 9:978-981. (Pubitemid 47190453)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.8
, pp. 978-981
-
-
Weinstock, D.M.1
Brunet, E.2
Jasin, M.3
-
11
-
-
33747888634
-
Modeling oncogenic translocations: Distinct roles for double-strand break repair pathways in translocation formation in mammalian cells
-
DOI 10.1016/j.dnarep.2006.05.028, PII S1568786406001686, Mechanisms of Chromosomal Translocations
-
Weinstock DM, Richardson CA, Elliott B, Jasin M (2006) Modeling oncogenic translocations: Distinct roles for double-strand break repair pathways in translocation formation in mammalian cells. DNA Repair (Amst) 5:1065-1074. (Pubitemid 44291619)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1065-1074
-
-
Weinstock, D.M.1
Richardson, C.A.2
Elliott, B.3
Jasin, M.4
-
12
-
-
1542287213
-
A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex
-
DOI 10.1038/nature02355
-
Raghavan SC, Swanson PC, Wu X, Hsieh CL, Lieber MR (2004) A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex. Nature 428:88-93. (Pubitemid 38332363)
-
(2004)
Nature
, vol.428
, Issue.6978
, pp. 88-93
-
-
Raghavan, S.C.1
Swanson, P.C.2
Wu, X.3
Hsieh, C.-L.4
Lieber, M.R.5
-
13
-
-
60549088880
-
Chromosomal location targets different MYC family gene members for oncogenic translocations
-
Gostissa M, Ranganath S, Bianco JM, Alt FW (2009) Chromosomal location targets different MYC family gene members for oncogenic translocations. Proc Natl Acad Sci USA 106:2265-2270.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2265-2270
-
-
Gostissa, M.1
Ranganath, S.2
Bianco, J.M.3
Alt, F.W.4
-
14
-
-
34948844963
-
Chromosomal reinsertion of broken RSS ends during T cell development
-
Curry JD, et al. (2007) Chromosomal reinsertion of broken RSS ends during T cell development. J Exp Med 204:2293-2303.
-
(2007)
J Exp Med
, vol.204
, pp. 2293-2303
-
-
Curry, J.D.1
-
15
-
-
3242887420
-
The role of the non-homologous end-joining pathway in lymphocyte development
-
DOI 10.1111/j.0105-2896.2004.00165.x
-
Rooney S, Chaudhuri J, Alt FW (2004) The role of the nonhomologous end-joining pathway in lymphocyte development. Immunol Rev 200:115-131. (Pubitemid 38998197)
-
(2004)
Immunological Reviews
, vol.200
, pp. 115-131
-
-
Rooney, S.1
Chaudhuri, J.2
Alt, F.W.3
-
16
-
-
33745132455
-
Genomic instability due to V(D)J recombination- Associated transposition
-
Reddy YV, Perkins EJ, Ramsden DA (2006) Genomic instability due to V(D)J recombination- associated transposition. Genes Dev 20:1575-1582.
-
(2006)
Genes Dev
, vol.20
, pp. 1575-1582
-
-
Reddy, Y.V.1
Perkins, E.J.2
Ramsden, D.A.3
-
17
-
-
0034612377
-
Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice
-
Petiniot LK, et al. (2000) Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice. Proc Natl Acad Sci USA 97:6664-6669.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6664-6669
-
-
Petiniot, L.K.1
-
18
-
-
33645072212
-
ATM-dependent DNA damage surveillance in T cell development and leukemogenesis: The DSB connection
-
Matei IR, Guidos CJ, Danska JS (2006) ATM-dependent DNA damage surveillance in T cell development and leukemogenesis: The DSB connection. Immunol Rev 209:142-158.
-
(2006)
Immunol Rev
, vol.209
, pp. 142-158
-
-
Matei, I.R.1
Guidos, C.J.2
Danska, J.S.3
-
19
-
-
0034284341
-
Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice
-
Liyanage M, et al. (2000) Abnormal rearrangement within the alpha/delta T cell receptor locus in lymphomas from Atm-deficient mice. Blood 96:1940-1946. (Pubitemid 30661081)
-
(2000)
Blood
, vol.96
, Issue.5
, pp. 1940-1946
-
-
Liyanage, M.1
Weaver, Z.2
Barlow, C.3
Coleman, A.4
Pankratz, D.G.5
Anderson, S.6
Wynshaw-Boris, A.7
Ried, T.8
-
20
-
-
0033563099
-
Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma
-
Liao MJ, Van Dyke T (1999) Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma. Genes Dev 13:1246-1250.
-
(1999)
Genes Dev
, vol.13
, pp. 1246-1250
-
-
Liao, M.J.1
Van Dyke, T.2
-
21
-
-
0030933152
-
The genetic defect in ataxia-telangiectasia
-
Lavin MF, Shiloh Y (1997) The genetic defect in ataxia-telangiectasia. Annu Rev Immunol 15:177-202.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 177-202
-
-
Lavin, M.F.1
Shiloh, Y.2
-
22
-
-
34250374139
-
Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes
-
Huang CY, et al. (2007) Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes. J Exp Med 204:1371-1381.
-
(2007)
J Exp Med
, vol.204
, pp. 1371-1381
-
-
Huang, C.Y.1
-
23
-
-
34447093903
-
ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes
-
DOI 10.1016/j.cell.2007.06.016, PII S0092867407007830
-
Callen E, et al. (2007) ATM prevents the persistence and propagation of chromosome breaks in lymphocytes. Cell 130:63-75. (Pubitemid 47031324)
-
(2007)
Cell
, vol.130
, Issue.1
, pp. 63-75
-
-
Callen, E.1
Jankovic, M.2
Difilippantonio, S.3
Daniel, J.A.4
Chen, H.-T.5
Celeste, A.6
Pellegrini, M.7
McBride, K.8
Wangsa, D.9
Bredemeyer, A.L.10
Sleckman, B.P.11
Ried, T.12
Nussenzweig, M.13
Nussenzweig, A.14
-
24
-
-
34447106461
-
ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor α locus coding end breaks
-
DOI 10.1073/pnas.0611222104
-
Vacchio MS, Olaru A, Livak F, Hodes RJ (2007) ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor α locus coding end breaks. Proc Natl Acad Sci USA 104:6323-6328. (Pubitemid 47186093)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.15
, pp. 6323-6328
-
-
Vacchio, M.S.1
Olaru, A.2
Livak, F.3
Hodes, R.J.4
-
25
-
-
33747097562
-
ATM stabilizes DNA double-strand-break complexes during V(D)J recombination
-
Bredemeyer AL, et al. (2006) ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature 442:466-470.
-
(2006)
Nature
, vol.442
, pp. 466-470
-
-
Bredemeyer, A.L.1
-
26
-
-
57649114834
-
DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes
-
Bredemeyer AL, et al. (2008) DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes. Nature 456:819-823.
-
(2008)
Nature
, vol.456
, pp. 819-823
-
-
Bredemeyer, A.L.1
-
27
-
-
0037232230
-
A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines
-
Muljo SA, Schlissel MS (2003) A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines. Nat Immunol 4:31-37.
-
(2003)
Nat Immunol
, vol.4
, pp. 31-37
-
-
Muljo, S.A.1
Schlissel, M.S.2
-
28
-
-
0003228073
-
Identification and utilization of arbitrary correlations in models of recombination signal sequences
-
research0072
-
Cowell LG, Davila M, Kepler TB, Kelsoe G (2002) Identification and utilization of arbitrary correlations in models of recombination signal sequences. Genome Biol 3:research0072.
-
(2002)
Genome Biol
, vol.3
-
-
Cowell, L.G.1
Davila, M.2
Kepler, T.B.3
Kelsoe, G.4
-
29
-
-
0024987973
-
Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasia lymphocytes
-
DOI 10.1084/jem.172.2.409
-
Lipkowitz S, Stern MH, Kirsch IR (1990) Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes. J Exp Med 172:409-418. (Pubitemid 20248382)
-
(1990)
Journal of Experimental Medicine
, vol.172
, Issue.2
, pp. 409-418
-
-
Lipkowitz, S.1
Stern, M.-H.2
Kirsch, I.R.3
-
30
-
-
0025954329
-
Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia
-
Kobayashi Y, Tycko B, Soreng AL, Sklar J (1991) Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia. J Immunol 147:3201-3209.
-
(1991)
J Immunol
, vol.147
, pp. 3201-3209
-
-
Kobayashi, Y.1
Tycko, B.2
Soreng, A.L.3
Sklar, J.4
-
31
-
-
33846606769
-
Antibody class switching mediated by yeast endonuclease-generated DNA breaks
-
Zarrin AA, et al. (2007) Antibody class switching mediated by yeast endonuclease-generated DNA breaks. Science 315:377-381.
-
(2007)
Science
, vol.315
, pp. 377-381
-
-
Zarrin, A.A.1
-
32
-
-
4644257681
-
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break
-
DOI 10.1016/j.cub.2004.09.047, PII S0960982204007419
-
Shroff R, et al. (2004) Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr Biol 14:1703-1711. (Pubitemid 39301159)
-
(2004)
Current Biology
, vol.14
, Issue.19
, pp. 1703-1711
-
-
Shroff, R.1
Arbel-Eden, A.2
Pilch, D.3
Ira, G.4
Bonner, W.M.5
Petrini, J.H.6
Haber, J.E.7
Lichten, M.8
-
33
-
-
65549129613
-
Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin
-
Savic V, et al. (2009) Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. Mol Cell 34:298-310.
-
(2009)
Mol Cell
, vol.34
, pp. 298-310
-
-
Savic, V.1
|