Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes

Toxicological Sciences

Volumn 133, Issue 1, 2013, Pages 54-66

  Forgacs, Agnes L ^a,b   Dere, Edward ^a   Angrish, Michelle M ^b   Zacharewski, Timothy R ^a,b  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Dioxin; Interspecies; Microarray; Primary hepatocyte

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; DIMETHYL SULFOXIDE;

ADULT; AGED; AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYP1A1 GENE; ENERGY METABOLISM; FATTY LIVER; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LIPID METABOLISM; LIPID STORAGE; LIPID TRANSPORT; LIVER CELL; MALE; MOUSE; NONHUMAN; ORTHOLOGY; RAT; SPECIES COMPARISON; TIPARP GENE;

ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION PROFILING; HEPATOCYTES; HUMANS; MALE; MICE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRIMARY CELL CULTURE; RATS; REAL-TIME POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; TETRACHLORODIBENZODIOXIN; TRANSCRIPTOME;

MUS; RATTUS;

EID: 84876803753     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft028     Document Type: Article

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