-
1
-
-
0028188487
-
Evidence of the role of the Ah receptor in responses to dioxin
-
Birnbaum, L. S. (1994). Evidence of the role of the Ah receptor in responses to dioxin. Prog. Clin. Biol. Res. 387, 139-154.
-
(1994)
Prog. Clin. Biol. Res.
, vol.387
, pp. 139-154
-
-
Birnbaum, L.S.1
-
2
-
-
71049174046
-
Divergent transcriptomic responses to aryl hydrocarbon receptor agonists between rat and human primary hepatocytes
-
Carlson, E. A., McCulloch, C., Koganti, A., Goodwin, S. B., Sutter, T. R., and Silkworth, J. B. (2009). Divergent transcriptomic responses to aryl hydrocarbon receptor agonists between rat and human primary hepatocytes. Toxicol. Sci. 112, 257-272.
-
(2009)
Toxicol. Sci.
, vol.112
, pp. 257-272
-
-
Carlson, E.A.1
McCulloch, C.2
Koganti, A.3
Goodwin, S.B.4
Sutter, T.R.5
Silkworth, J.B.6
-
3
-
-
2542635631
-
Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha
-
Cheung, C., Akiyama, T. E., Ward, J. M., Nicol, C. J., Feigenbaum, L., Vinson, C., and Gonzalez, F. J. (2004). Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha. Cancer Res. 64, 3849-3854.
-
(2004)
Cancer Res.
, vol.64
, pp. 3849-3854
-
-
Cheung, C.1
Akiyama, T.E.2
Ward, J.M.3
Nicol, C.J.4
Feigenbaum, L.5
Vinson, C.6
Gonzalez, F.J.7
-
4
-
-
0033564553
-
Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially
-
Ciolino, H. P., Daschner, P. J., and Yeh, G. C. (1999). Dietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentially. Biochem. J. 340(Pt 3), 715-722.
-
(1999)
Biochem. J.
, vol.340
, Issue.PT 3
, pp. 715-722
-
-
Ciolino, H.P.1
Daschner, P.J.2
Yeh, G.C.3
-
5
-
-
0037135582
-
The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate
-
Cui, J., Heard, T. S., Yu, J., Lo, J. L., Huang, L., Li, Y., Schaeffer, J. M., and Wright, S. D. (2002). The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate. J. Biol. Chem. 277, 25963-25969.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25963-25969
-
-
Cui, J.1
Heard, T.S.2
Yu, J.3
Lo, J.L.4
Huang, L.5
Li, Y.6
Schaeffer, J.M.7
Wright, S.D.8
-
6
-
-
0037144119
-
Ligand binding and activation of the Ah receptor
-
Denison, M. S., Pandini, A., Nagy, S. R., Baldwin, E. P., and Bonati, L. (2002). Ligand binding and activation of the Ah receptor. Chem. Biol. Interact. 141, 3-24.
-
(2002)
Chem. Biol. Interact.
, vol.141
, pp. 3-24
-
-
Denison, M.S.1
Pandini, A.2
Nagy, S.R.3
Baldwin, E.P.4
Bonati, L.5
-
7
-
-
0023033162
-
Structure and function of the Ah receptor for 2,3,7 8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols
-
Denison, M. S., Vella, L. M., and Okey, A. B. (1986). Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols. J. Biol. Chem. 261, 3987-3995.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 3987-3995
-
-
Denison, M.S.1
Vella, L.M.2
Okey, A.B.3
-
8
-
-
0038005018
-
DAVID: Database for Annotation, Visualization, and Integrated Discovery
-
Dennis, G., Jr, Sherman, B. T., Hosack, D. A., Yang, J., Gao, W., Lane, H. C., and Lempicki, R. A. (2003). DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 4, P3.
-
(2003)
Genome Biol.
, vol.4
-
-
Dennis G., Jr.1
Sherman, B.T.2
Hosack, D.A.3
Yang, J.4
Gao, W.5
Lane, H.C.6
Lempicki, R.A.7
-
9
-
-
0028034621
-
Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors
-
Ema, M., Ohe, N., Suzuki, M., Mimura, J., Sogawa, K., Ikawa, S., and Fujii-Kuriyama, Y. (1994). Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors. J. Biol. Chem. 269, 27337-27343.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27337-27343
-
-
Ema, M.1
Ohe, N.2
Suzuki, M.3
Mimura, J.4
Sogawa, K.5
Ikawa, S.6
Fujii-Kuriyama, Y.7
-
10
-
-
39749191311
-
The mouse and human Ah receptor differ in recognition of LXXLL motifs
-
Flaveny, C., Reen, R. K., Kusnadi, A., and Perdew, G. H. (2008). The mouse and human Ah receptor differ in recognition of LXXLL motifs. Arch. Biochem. Biophys. 471, 215-223.
-
(2008)
Arch. Biochem. Biophys.
, vol.471
, pp. 215-223
-
-
Flaveny, C.1
Reen, R.K.2
Kusnadi, A.3
Perdew, G.H.4
-
11
-
-
66849125992
-
Ligand selectivity and gene regulation by the human aryl hydrocarbon receptor in transgenic mice
-
Flaveny, C. A., Murray, I. A., Chiaro, C. R., and Perdew, G. H. (2009). Ligand selectivity and gene regulation by the human aryl hydrocarbon receptor in transgenic mice. Mol. Pharmacol. 75, 1412-1420.
-
(2009)
Mol. Pharmacol.
, vol.75
, pp. 1412-1420
-
-
Flaveny, C.A.1
Murray, I.A.2
Chiaro, C.R.3
Perdew, G.H.4
-
12
-
-
1542267434
-
Aryl hydrocarbon receptor response to indigoids in vitro and in vivo
-
Guengerich, P. F., Martin, M. V., McCormick, W. A., Nguyen, L. P., Glover, E., and Bradfield, C. A. (2004). Aryl hydrocarbon receptor response to indigoids in vitro and in vivo. Arch. Biochem. Biophys. 423, 309-316.
-
(2004)
Arch. Biochem. Biophys.
, vol.423
, pp. 309-316
-
-
Guengerich, P.F.1
Martin, M.V.2
McCormick, W.A.3
Nguyen, L.P.4
Glover, E.5
Bradfield, C.A.6
-
13
-
-
0019493439
-
2,3,7,8-tetrachlorodibenzo-p-dioxin: acute oral toxicity in hamsters
-
Henck, J. M., New, M. A., Kociba, R. J., and Rao, K. S. (1981). 2,3,7,8-tetrachlorodibenzo-p-dioxin: acute oral toxicity in hamsters. Toxicol. Appl. Pharmacol. 59, 405-408.
-
(1981)
Toxicol. Appl. Pharmacol.
, vol.59
, pp. 405-408
-
-
Henck, J.M.1
New, M.A.2
Kociba, R.J.3
Rao, K.S.4
-
14
-
-
5044237671
-
Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR
-
Huang, W., Zhang, J., Wei, P., Schrader, W. T., and Moore, D. D. (2004). Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR. Mol. Endocrinol. 18, 2402-2408.
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 2402-2408
-
-
Huang, W.1
Zhang, J.2
Wei, P.3
Schrader, W.T.4
Moore, D.D.5
-
15
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da, W., Sherman, B. T., and Lempicki, R. A. (2009). Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 44-57
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
16
-
-
0029918651
-
Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon-and estrogen-mediated signaling
-
Kharat, I., and Saatcioglu, F. (1996). Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. Cross-talk between aryl hydrocarbon-and estrogen-mediated signaling. J. Biol. Chem. 271, 10533-10537.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10533-10537
-
-
Kharat, I.1
Saatcioglu, F.2
-
17
-
-
0034676269
-
The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells
-
Kim, D. W., Gazourian, L., Quadri, S. A., Romieu-Mourez, R., Sherr, D. H., and Sonenshein, G. E. (2000). The RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells. Oncogene 19, 5498-5506.
-
(2000)
Oncogene
, vol.19
, pp. 5498-5506
-
-
Kim, D.W.1
Gazourian, L.2
Quadri, S.A.3
Romieu-Mourez, R.4
Sherr, D.H.5
Sonenshein, G.E.6
-
18
-
-
0029019489
-
Transcriptional activation by the mouse Ah receptor
-
Ma, Q., Dong, L., and Whitlock, J. P., Jr. (1995). Transcriptional activation by the mouse Ah receptor. J. Biol. Chem. 270, 12697-12703.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12697-12703
-
-
Ma, Q.1
Dong, L.2
Whitlock J.P., Jr.3
-
19
-
-
0034022192
-
Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic mice
-
Madden, C. R., Finegold, M. J., and Slagle, B. L. (2000). Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic mice. J. Virol. 74, 5266-5272.
-
(2000)
J. Virol.
, vol.74
, pp. 5266-5272
-
-
Madden, C.R.1
Finegold, M.J.2
Slagle, B.L.3
-
20
-
-
0037610805
-
Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse
-
Moriguchi, T., Motohashi, H., Hosoya, T., Nakajima, O., Takahashi, S., Ohsako, S., Aoki, Y., Nishimura, N., Tohyama, C., Fujii-Kuriyama, Y., et al. (2003). Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse. Proc. Natl. Acad. Sci. U.S.A. 100, 5652-5657.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 5652-5657
-
-
Moriguchi, T.1
Motohashi, H.2
Hosoya, T.3
Nakajima, O.4
Takahashi, S.5
Ohsako, S.6
Aoki, Y.7
Nishimura, N.8
Tohyama, C.9
Fujii-Kuriyama, Y.10
-
21
-
-
0018609570
-
Regulatory gene product of the Ah locus Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation
-
Okey, A. B., Bondy, G. P., Mason, M. E., Kahl, G. F., Eisen, H. J., Guenthner, T. M., and Nebert, D. W. (1979). Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation. J. Biol. Chem. 254, 11636-11648.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 11636-11648
-
-
Okey, A.B.1
Bondy, G.P.2
Mason, M.E.3
Kahl, G.F.4
Eisen, H.J.5
Guenthner, T.M.6
Nebert, D.W.7
-
22
-
-
0035999977
-
A comparative review of statistical methods for discovering differentially expressed genes in replicated microarray experiments
-
Pan, W. (2002). A comparative review of statistical methods for discovering differentially expressed genes in replicated microarray experiments. Bioinformatics 18, 546-554.
-
(2002)
Bioinformatics
, vol.18
, pp. 546-554
-
-
Pan, W.1
-
23
-
-
66549088712
-
Ah receptor represses acute-phase response gene expression without binding to its cognate response element
-
Patel, R. D., Murray, I. A., Flaveny, C. A., Kusnadi, A., and Perdew, G. H. (2009). Ah receptor represses acute-phase response gene expression without binding to its cognate response element. Lab. Invest. 89, 695-707.
-
(2009)
Lab. Invest.
, vol.89
, pp. 695-707
-
-
Patel, R.D.1
Murray, I.A.2
Flaveny, C.A.3
Kusnadi, A.4
Perdew, G.H.5
-
24
-
-
0027257203
-
Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 1,2,3,4,7 8-hexachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain
-
Pohjanvirta, R., Unkila, M., and Tuomisto, J. (1993). Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain. Pharmacol. Toxicol. 73, 52-56.
-
(1993)
Pharmacol. Toxicol.
, vol.73
, pp. 52-56
-
-
Pohjanvirta, R.1
Unkila, M.2
Tuomisto, J.3
-
25
-
-
0025074762
-
Characterization and strain distribution pattern of the murine Ah receptor specified by the Ahd and Ahb-3 alleles
-
Poland, A., and Glover, E. (1990). Characterization and strain distribution pattern of the murine Ah receptor specified by the Ahd and Ahb-3 alleles. Mol. Pharmacol. 38, 306-312.
-
(1990)
Mol. Pharmacol.
, vol.38
, pp. 306-312
-
-
Poland, A.1
Glover, E.2
-
26
-
-
0023518502
-
The murine Ah locus: a new allele and mapping to chromosome 12
-
Poland, A., Glover, E., and Taylor, B. A. (1987). The murine Ah locus: a new allele and mapping to chromosome 12. Mol. Pharmacol. 32, 471-478.
-
(1987)
Mol. Pharmacol.
, vol.32
, pp. 471-478
-
-
Poland, A.1
Glover, E.2
Taylor, B.A.3
-
27
-
-
0020010617
-
2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity
-
Poland, A., and Knutson, J. C. (1982). 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22, 517-554.
-
(1982)
Annu. Rev. Pharmacol. Toxicol.
, vol.22
, pp. 517-554
-
-
Poland, A.1
Knutson, J.C.2
-
28
-
-
0027944549
-
Analysis of the four alleles of the murine aryl hydrocarbon receptor
-
Poland, A., Palen, D., and Glover, E. (1994). Analysis of the four alleles of the murine aryl hydrocarbon receptor. Mol. Pharmacol. 46, 915-921.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 915-921
-
-
Poland, A.1
Palen, D.2
Glover, E.3
-
29
-
-
3042677511
-
Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-p-dioxin as a probe to determine the relative ligand affinity of human versus mouse aryl hydrocarbon receptor in cultured cells
-
Ramadoss, P., and Perdew, G. H. (2004). Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-p-dioxin as a probe to determine the relative ligand affinity of human versus mouse aryl hydrocarbon receptor in cultured cells. Mol. Pharmacol. 66, 129-136.
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 129-136
-
-
Ramadoss, P.1
Perdew, G.H.2
-
31
-
-
4344590127
-
Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences
-
Sun, Y. V., Boverhof, D. R., Burgoon, L. D., Fielden, M. R., and Zacharewski, T. R. (2004). Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences. Nucleic Acids Res. 32, 4512-4523.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 4512-4523
-
-
Sun, Y.V.1
Boverhof, D.R.2
Burgoon, L.D.3
Fielden, M.R.4
Zacharewski, T.R.5
-
32
-
-
0025934316
-
Targets for dioxin: genes for plasminogen activator-2 and interleukin-1
-
Sutter, T. R., Guzman, K., Dold, K. M., and Greenlee, W. F. (1991). Targets for dioxin: genes for plasminogen activator-2 and interleukin-1. Science 254, 811-828.
-
(1991)
Science
, vol.254
, pp. 811-828
-
-
Sutter, T.R.1
Guzman, K.2
Dold, K.M.3
Greenlee, W.F.4
-
33
-
-
0027458138
-
The AH-receptor: genetics, structure and function
-
Swanson, H. I., and Bradfield, C. A. (1993). The AH-receptor: genetics, structure and function. Pharmacogenetics 3, 213.
-
(1993)
Pharmacogenetics
, vol.3
, pp. 213
-
-
Swanson, H.I.1
Bradfield, C.A.2
-
35
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher, V. G., Tibshirani, R., and Chu, G. (2001). Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. U.S.A. 98, 5116-5121.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
36
-
-
59149104324
-
A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family
-
Vogel, C. F., and Matsumura, F. (2009). A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family. Biochem. Pharmacol. 77, 734-745.
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 734-745
-
-
Vogel, C.F.1
Matsumura, F.2
-
37
-
-
29144483934
-
Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types
-
Walisser, J. A., Glover, E., Pande, K., Liss, A. L., and Bradfield, C. A. (2005). Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types. Proc. Natl. Acad. Sci. U.S.A. 102, 17858-17863.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 17858-17863
-
-
Walisser, J.A.1
Glover, E.2
Pande, K.3
Liss, A.L.4
Bradfield, C.A.5
-
38
-
-
0029084423
-
H-ras oncogene mutation spectra in B6C3F1 and C57BL/6 mouse liver tumors provide evidence for TCDD promotion of spontaneous and vinyl carbamate-initiated liver cells
-
Watson, M. A., Devereux, T. R., Malarkey, D. E., Anderson, M. A., and Maronport, R. R. (1995). H-ras oncogene mutation spectra in B6C3F1 and C57BL/6 mouse liver tumors provide evidence for TCDD promotion of spontaneous and vinyl carbamate-initiated liver cells. Carcinogenesis 16, 1705-1710.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1705-1710
-
-
Watson, M.A.1
Devereux, T.R.2
Malarkey, D.E.3
Anderson, M.A.4
Maronport, R.R.5
-
39
-
-
0028951478
-
Correlation between toxicity and effects on intermediary metabolism in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated male C57BL/6J and DBA/2J mice
-
Weber, L. W. D., Lebofsky, M., Stahl, B. U., Smith, S., and Rozman, K. K. (1995). Correlation between toxicity and effects on intermediary metabolism in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated male C57BL/6J and DBA/2J mice. Toxicol. Appl. Pharmacol. 131, 155-162.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.131
, pp. 155-162
-
-
Weber, L.W.D.1
Lebofsky, M.2
Stahl, B.U.3
Smith, S.4
Rozman, K.K.5
|