-
1
-
-
33644955272
-
Mouse models in non-alcoholic fatty liver disease and steatohepatitis research
-
Anstee QM and Goldin RD (2006) Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. Int J Exp Pathol 87:1-16.
-
(2006)
Int J Exp Pathol
, vol.87
, pp. 1-16
-
-
Anstee, Q.M.1
Goldin, R.D.2
-
2
-
-
43449094989
-
Bile acid levels are increased in the liver of patients with steatohepatitis
-
Aranha MM, Cortez-Pinto H, Costa A, da Silva IB, Camilo ME, de Moura MC, and Rodrigues CM (2008) Bile acid levels are increased in the liver of patients with steatohepatitis. Eur J Gastroenterol Hepatol 20:519-525.
-
(2008)
Eur J Gastroenterol Hepatol
, vol.20
, pp. 519-525
-
-
Aranha, M.M.1
Cortez-Pinto, H.2
Costa, A.3
da Silva, I.B.4
Camilo, M.E.5
de Moura, M.C.6
Rodrigues, C.M.7
-
3
-
-
38649110496
-
Hepatic Insulin Resistance Is Sufficient to Produce Dyslipidemia and Susceptibility to Atherosclerosis
-
Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, et al. (2008) Hepatic Insulin Resistance Is Sufficient to Produce Dyslipidemia and Susceptibility to Atherosclerosis. Cell Metab 7:125-134.
-
(2008)
Cell Metab
, vol.7
, pp. 125-134
-
-
Biddinger, S.B.1
Hernandez-Ono, A.2
Rask-Madsen, C.3
Haas, J.T.4
Alemán, J.O.5
Suzuki, R.6
Scapa, E.F.7
Agarwal, C.8
Carey, M.C.9
Stephanopoulos, G.10
-
4
-
-
18244364864
-
NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
-
Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, Fung C, Karim R, Lin R, Samarasinghe D, Liddle C, et al. (2002) NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 35:373-379.
-
(2002)
Hepatology
, vol.35
, pp. 373-379
-
-
Chitturi, S.1
Abeygunasekera, S.2
Farrell, G.C.3
Holmes-Walker, J.4
Hui, J.M.5
Fung, C.6
Karim, R.7
Lin, R.8
Samarasinghe, D.9
Liddle, C.10
-
5
-
-
61349117244
-
Prevention of hepatic fibrosis in a murine model of metabolic syndrome with non-alcoholic steatohepatitis (NASH)
-
DeLeve LD, Wang X, Kanel GC, Atkinson R, and McCuskey RS (2007) Prevention of hepatic fibrosis in a murine model of metabolic syndrome with non-alcoholic steatohepatitis (NASH). Hepatology 46:761A-762A.
-
(2007)
Hepatology
, vol.46
-
-
DeLeve, L.D.1
Wang, X.2
Kanel, G.C.3
Atkinson, R.4
McCuskey, R.S.5
-
6
-
-
25844456719
-
Steatohepatitis induced by intragastric overfeeding in mice
-
Deng QG, She H, Cheng JH, French SW, Koop DR, Xiong S, and Tsukamoto H (2005) Steatohepatitis induced by intragastric overfeeding in mice. Hepatology 42:905-914.
-
(2005)
Hepatology
, vol.42
, pp. 905-914
-
-
Deng, Q.G.1
She, H.2
Cheng, J.H.3
French, S.W.4
Koop, D.R.5
Xiong, S.6
Tsukamoto, H.7
-
7
-
-
32944455840
-
Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes
-
Dent P, Fang Y, Gupta S, Studer E, Mitchell C, Spiegel S, and Hylemon PB (2005) Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes. Hepatology 42:1291-1299.
-
(2005)
Hepatology
, vol.42
, pp. 1291-1299
-
-
Dent, P.1
Fang, Y.2
Gupta, S.3
Studer, E.4
Mitchell, C.5
Spiegel, S.6
Hylemon, P.B.7
-
8
-
-
33644547706
-
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
-
Farrell GC and Larter CZ (2006) Nonalcoholic fatty liver disease: From steatosis to cirrhosis. Hepatology 43:S99-S112.
-
(2006)
Hepatology
, vol.43
-
-
Farrell, G.C.1
Larter, C.Z.2
-
9
-
-
0020472786
-
The LDL receptor defect in familial hypercholesterolemia: Implications for pathogenesis and therapy
-
Goldstein JL and Brown MS (1982) The LDL receptor defect in familial hypercholesterolemia: implications for pathogenesis and therapy. Med Clin North Am 66:335-362.
-
(1982)
Med Clin North Am
, vol.66
, pp. 335-362
-
-
Goldstein, J.L.1
Brown, M.S.2
-
10
-
-
0242665373
-
Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity
-
Guo GL, Lambert G, Negishi M, Ward JM, Brewer HB Jr, Kliewer SA, Gonzalez FJ, and Sinal CJ (2003) Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity. J Biol Chem 278:45062-45071.
-
(2003)
J Biol Chem
, vol.278
, pp. 45062-45071
-
-
Guo, G.L.1
Lambert, G.2
Negishi, M.3
Ward, J.M.4
Brewer Jr, H.B.5
Kliewer, S.A.6
Gonzalez, F.J.7
Sinal, C.J.8
-
11
-
-
34247477399
-
Effects of FXR in foam-cell formation and atherosclerosis development
-
Guo GL, Santamarina-Fojo S, Akiyama TE, Amar MJ, Paigen BJ, Brewer B Jr, and Gonzalez FJ (2006) Effects of FXR in foam-cell formation and atherosclerosis development. Biochim Biophys Acta 1761:1401-1409.
-
(2006)
Biochim Biophys Acta
, vol.1761
, pp. 1401-1409
-
-
Guo, G.L.1
Santamarina-Fojo, S.2
Akiyama, T.E.3
Amar, M.J.4
Paigen, B.J.5
Brewer Jr, B.6
Gonzalez, F.J.7
-
12
-
-
38649110476
-
The pathogenesis of ethanol versus methionine and choline deficient diet-induced liver injury
-
Gyamfi MA, Damjanov I, French S, and Wan YJ (2008) The pathogenesis of ethanol versus methionine and choline deficient diet-induced liver injury. Biochem Pharmacol 75:981-995.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 981-995
-
-
Gyamfi, M.A.1
Damjanov, I.2
French, S.3
Wan, Y.J.4
-
13
-
-
30844436795
-
Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice
-
Hanniman EA, Lambert G, McCarthy TC, and Sinal CJ (2005) Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice. J Lipid Res 46:2595-2604.
-
(2005)
J Lipid Res
, vol.46
, pp. 2595-2604
-
-
Hanniman, E.A.1
Lambert, G.2
McCarthy, T.C.3
Sinal, C.J.4
-
14
-
-
33750312176
-
Histological assessment of non-alcoholic fatty liver disease
-
Hubscher SG (2006) Histological assessment of non-alcoholic fatty liver disease. Histopathology 49:450-465.
-
(2006)
Histopathology
, vol.49
, pp. 450-465
-
-
Hubscher, S.G.1
-
15
-
-
0028345073
-
Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
-
Ishibashi S, Goldstein JL, Brown MS, Herz J, and Burns DK (1994) Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J Clin Invest 93:1885-1893.
-
(1994)
J Clin Invest
, vol.93
, pp. 1885-1893
-
-
Ishibashi, S.1
Goldstein, J.L.2
Brown, M.S.3
Herz, J.4
Burns, D.K.5
-
16
-
-
0036163759
-
Mechanisms of hepatotoxicity
-
Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, and Lemasters JJ (2002) Mechanisms of hepatotoxicity. Toxicol Sci 65:166-176.
-
(2002)
Toxicol Sci
, vol.65
, pp. 166-176
-
-
Jaeschke, H.1
Gores, G.J.2
Cederbaum, A.I.3
Hinson, J.A.4
Pessayre, D.5
Lemasters, J.J.6
-
17
-
-
0032171686
-
Non-alcoholic steatohepatitis (NASH): A disease of emerging identity and importance
-
James OF and Day CP (1998) Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance. J Hepatol 29:495-501.
-
(1998)
J Hepatol
, vol.29
, pp. 495-501
-
-
James, O.F.1
Day, C.P.2
-
18
-
-
0034791544
-
Farnesoid X-activated receptor induces apolipoprotein C-II transcription: A molecular mechanism linking plasma triglyceride levels to bile acids
-
Kast HR, Nguyen CM, Sinal CJ, Jones SA, Laffitte BA, Reue K, Gonzalez FJ, Willson TM, and Edwards PA (2001) Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids. Mol Endocrinol 15:1720-1728.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1720-1728
-
-
Kast, H.R.1
Nguyen, C.M.2
Sinal, C.J.3
Jones, S.A.4
Laffitte, B.A.5
Reue, K.6
Gonzalez, F.J.7
Willson, T.M.8
Edwards, P.A.9
-
19
-
-
44649092024
-
Expression and function of the bile acid receptor TGR5 in Kupffer cells
-
Keitel V, Donner M, Winandy S, Kubitz R, and Haussinger D (2008) Expression and function of the bile acid receptor TGR5 in Kupffer cells. Biochem Biophys Res Commun 372:78-84.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 78-84
-
-
Keitel, V.1
Donner, M.2
Winandy, S.3
Kubitz, R.4
Haussinger, D.5
-
20
-
-
33947383769
-
The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells
-
Keitel V, Reinehr R, Gatsios P, Rupprecht C, Görg B, Selbach O, Häussinger D, and Kubitz R (2007) The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells. Hepatology 45:695-704.
-
(2007)
Hepatology
, vol.45
, pp. 695-704
-
-
Keitel, V.1
Reinehr, R.2
Gatsios, P.3
Rupprecht, C.4
Görg, B.5
Selbach, O.6
Häussinger, D.7
Kubitz, R.8
-
21
-
-
33645128199
-
Early growth response factor-1 is critical for cholestatic liver injury
-
Kim ND, Moon JO, Slitt AL, and Copple BL (2006) Early growth response factor-1 is critical for cholestatic liver injury. Toxicol Sci 90:586-595.
-
(2006)
Toxicol Sci
, vol.90
, pp. 586-595
-
-
Kim, N.D.1
Moon, J.O.2
Slitt, A.L.3
Copple, B.L.4
-
22
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
KleinerDE,BruntEM,VanNattaM,BehlingC,ContosMJ,CummingsOW,Ferrell LD, Liu YC, Torbenson MS, Unalp-Arida A, et al. (2005) Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41:1313-1321.
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
VanNatta, M.3
Behling, C.4
Contos, M.J.5
Cummings, O.W.6
Ferrell, L.D.7
Liu, Y.C.8
Torbenson, M.S.9
Unalp-Arida, A.10
-
23
-
-
0037462815
-
The farnesoid X-receptor is an essential regulator of cholesterol homeostasis
-
Lambert G, Amar MJ, Guo G, Brewer HB Jr, Gonzalez FJ, and Sinal CJ (2003) The farnesoid X-receptor is an essential regulator of cholesterol homeostasis. J Biol Chem 278:2563-2570.
-
(2003)
J Biol Chem
, vol.278
, pp. 2563-2570
-
-
Lambert, G.1
Amar, M.J.2
Guo, G.3
Brewer Jr, H.B.4
Gonzalez, F.J.5
Sinal, C.J.6
-
24
-
-
1242290584
-
Model of nonalcoholic steatohepatitis
-
Lieber CS, Leo MA, Mak KM, Xu Y, Cao Q, Ren C, Ponomarenko A, and DeCarli LM (2004) Model of nonalcoholic steatohepatitis. Am J Clin Nutr 79:502-509.
-
(2004)
Am J Clin Nutr
, vol.79
, pp. 502-509
-
-
Lieber, C.S.1
Leo, M.A.2
Mak, K.M.3
Xu, Y.4
Cao, Q.5
Ren, C.6
Ponomarenko, A.7
DeCarli, L.M.8
-
25
-
-
0346690402
-
Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis
-
Liu Y, Binz J, Numerick MJ, Dennis S, Luo G, Desai B, MacKenzie KI, Mansfield TA, Kliewer SA, Goodwin B, et al. (2003) Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis. J Clin Invest 112:1678-1687.
-
(2003)
J Clin Invest
, vol.112
, pp. 1678-1687
-
-
Liu, Y.1
Binz, J.2
Numerick, M.J.3
Dennis, S.4
Luo, G.5
Desai, B.6
MacKenzie, K.I.7
Mansfield, T.A.8
Kliewer, S.A.9
Goodwin, B.10
-
26
-
-
35348845091
-
Non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease: An open question
-
Loria P, Lonardo A, Bellentani S, Day CP, Marchesini G, and Carulli N (2007) Non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease: an open question. Nutr Metab Cardiovasc Dis 17:684-698.
-
(2007)
Nutr Metab Cardiovasc Dis
, vol.17
, pp. 684-698
-
-
Loria, P.1
Lonardo, A.2
Bellentani, S.3
Day, C.P.4
Marchesini, G.5
Carulli, N.6
-
27
-
-
33645509321
-
Farnesoid X receptor is essential for normal glucose homeostasis
-
Ma K, Saha PK, Chan L, and Moore DD (2006) Farnesoid X receptor is essential for normal glucose homeostasis. J Clin Invest 116:1102-1109.
-
(2006)
J Clin Invest
, vol.116
, pp. 1102-1109
-
-
Ma, K.1
Saha, P.K.2
Chan, L.3
Moore, D.D.4
-
28
-
-
51349135630
-
Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice
-
Ma KL, Ruan XZ, Powis SH, Chen Y, Moorhead JF, and Varghese Z (2008) Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice. Hepatology 48:770-781.
-
(2008)
Hepatology
, vol.48
, pp. 770-781
-
-
Ma, K.L.1
Ruan, X.Z.2
Powis, S.H.3
Chen, Y.4
Moorhead, J.F.5
Varghese, Z.6
-
29
-
-
0034632762
-
Identification of a chemical tool for the orphan nuclear receptor FXR
-
Maloney PR, Parks DJ, Haffner CD, Fivush AM, Chandra G, Plunket KD, Creech KL, Moore LB, Wilson JG, Lewis MC, et al. (2000) Identification of a chemical tool for the orphan nuclear receptor FXR. J Med Chem 43:2971-2974.
-
(2000)
J Med Chem
, vol.43
, pp. 2971-2974
-
-
Maloney, P.R.1
Parks, D.J.2
Haffner, C.D.3
Fivush, A.M.4
Chandra, G.5
Plunket, K.D.6
Creech, K.L.7
Moore, L.B.8
Wilson, J.G.9
Lewis, M.C.10
-
30
-
-
34547431187
-
A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression
-
Marzolini C, Tirona RG, Gervasini G, Poonkuzhali B, Assem M, Lee W, Leake BF, Schuetz JD, Schuetz EG, and Kim RB (2007) A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression. Mol Endocrinol 21:1769-1780.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1769-1780
-
-
Marzolini, C.1
Tirona, R.G.2
Gervasini, G.3
Poonkuzhali, B.4
Assem, M.5
Lee, W.6
Leake, B.F.7
Schuetz, J.D.8
Schuetz, E.G.9
Kim, R.B.10
-
31
-
-
0029759909
-
The roleofearlygrowthresponsegene1 (egr-1) in regulation of the immune response
-
and MonroeJG
-
McMahon SB and MonroeJG(1996) The roleofearlygrowthresponsegene1 (egr-1) in regulation of the immune response. J Leukoc Biol 60:159-166.
-
(1996)
J Leukoc Biol
, vol.60
, pp. 159-166
-
-
McMahon, S.B.1
-
32
-
-
33646575949
-
Association between postprandial LDL conjugated dienes and the severity of liver fibrosis in NASH
-
Musso G, Cassader M, Gambino R, Durazzo M, and Pagano G (2006) Association between postprandial LDL conjugated dienes and the severity of liver fibrosis in NASH. Hepatology 43:1169-1170.
-
(2006)
Hepatology
, vol.43
, pp. 1169-1170
-
-
Musso, G.1
Cassader, M.2
Gambino, R.3
Durazzo, M.4
Pagano, G.5
-
33
-
-
0033591387
-
Bile acids: Natural ligands for an orphan nuclear receptor
-
Parks DJ, Blanchard SG, Bledsoe RK, Chandra G, Consler TG, Kliewer SA, Stimmel JB, Willson TM, Zavacki AM, Moore DD, et al. (1999) Bile acids: natural ligands for an orphan nuclear receptor. Science 284:1365-1368.
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
Blanchard, S.G.2
Bledsoe, R.K.3
Chandra, G.4
Consler, T.G.5
Kliewer, S.A.6
Stimmel, J.B.7
Willson, T.M.8
Zavacki, A.M.9
Moore, D.D.10
-
34
-
-
0037405649
-
Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes
-
Qiao L, Han SI, Fang Y, Park JS, Gupta S, Gilfor D, Amorino G, Valerie K, Sealy L, Engelhardt JF, et al. (2003) Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes. Mol Cell Biol 23:3052-3066.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3052-3066
-
-
Qiao, L.1
Han, S.I.2
Fang, Y.3
Park, J.S.4
Gupta, S.5
Gilfor, D.6
Amorino, G.7
Valerie, K.8
Sealy, L.9
Engelhardt, J.F.10
-
35
-
-
0036151709
-
Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes
-
Rao YP, Studer EJ, Stravitz RT, Gupta S, Qiao L, Dent P, and Hylemon PB (2002) Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. Hepatology 35:307-314.
-
(2002)
Hepatology
, vol.35
, pp. 307-314
-
-
Rao, Y.P.1
Studer, E.J.2
Stravitz, R.T.3
Gupta, S.4
Qiao, L.5
Dent, P.6
Hylemon, P.B.7
-
36
-
-
39849099669
-
Non-alcoholic fatty liver disease and the metabolic syndrome: An update
-
Rector RS, Thyfault JP, Wei Y, and Ibdah JA (2008) Non-alcoholic fatty liver disease and the metabolic syndrome: an update. World J Gastroenterol 14:185-192.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 185-192
-
-
Rector, R.S.1
Thyfault, J.P.2
Wei, Y.3
Ibdah, J.A.4
-
37
-
-
33947169979
-
Alanine aminotransferase predicts coronary heart disease events: A 10-year follow-up of the Hoorn Study
-
Schindhelm RK, Dekker JM, Nijpels G, Bouter LM, Stehouwer CD, Heine RJ, and Diamant M (2007a) Alanine aminotransferase predicts coronary heart disease events: a 10-year follow-up of the Hoorn Study. Atherosclerosis 191:391-396.
-
(2007)
Atherosclerosis
, vol.191
, pp. 391-396
-
-
Schindhelm, R.K.1
Dekker, J.M.2
Nijpels, G.3
Bouter, L.M.4
Stehouwer, C.D.5
Heine, R.J.6
Diamant, M.7
-
38
-
-
34548405639
-
Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients
-
Schindhelm RK, Heine RJ, and Diamant M (2007b) Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients. Diabetes Care 30:e94-e95.
-
(2007)
Diabetes Care
, vol.30
-
-
Schindhelm, R.K.1
Heine, R.J.2
Diamant, M.3
-
39
-
-
33644919989
-
Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates
-
Shiri-Sverdlov R, Wouters K, van Gorp PJ, Gijbels MJ, Noel B, Buffat L, Staels B, Maeda N, van Bilsen M, and Hofker MH (2006) Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. J Hepatol 44:732-741.
-
(2006)
J Hepatol
, vol.44
, pp. 732-741
-
-
Shiri-Sverdlov, R.1
Wouters, K.2
van Gorp, P.J.3
Gijbels, M.J.4
Noel, B.5
Buffat, L.6
Staels, B.7
Maeda, N.8
van Bilsen, M.9
Hofker, M.H.10
-
40
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal CJ, Tohkin M, Miyata M, Ward JM, Lambert G, and Gonzalez FJ (2000) Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102:731-744.
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
Tohkin, M.2
Miyata, M.3
Ward, J.M.4
Lambert, G.5
Gonzalez, F.J.6
-
41
-
-
44449120940
-
Independent Predictors of Steatohepatitis and Fibrosis in Asian Indian Patients with Non-Alcoholic Steatohepatitis
-
Singh DK, Sakhuja P, Malhotra V, Gondal R, and Sarin SK (2008) Independent Predictors of Steatohepatitis and Fibrosis in Asian Indian Patients with Non-Alcoholic Steatohepatitis. Digest Dis Sci 53:1967-1976.
-
(2008)
Digest Dis Sci
, vol.53
, pp. 1967-1976
-
-
Singh, D.K.1
Sakhuja, P.2
Malhotra, V.3
Gondal, R.4
Sarin, S.K.5
-
42
-
-
20844448737
-
A clinical-morphological study on cholestatic presentation of nonalcoholic fatty liver disease
-
Sorrentino P, Tarantino G, Perrella A, Micheli P, Perrella O, and Conca P (2005) A clinical-morphological study on cholestatic presentation of nonalcoholic fatty liver disease. Dig Dis Sci 50:1130-1135.
-
(2005)
Dig Dis Sci
, vol.50
, pp. 1130-1135
-
-
Sorrentino, P.1
Tarantino, G.2
Perrella, A.3
Micheli, P.4
Perrella, O.5
Conca, P.6
-
43
-
-
14244253957
-
Feeding apolipoprotein E-knockout mice with cholesterol and fat enriched diets may be a model of nonalcoholic steatohepatitis
-
Tous M, Ferré N, Camps J, Riu F, and Joven J (2005) Feeding apolipoprotein E-knockout mice with cholesterol and fat enriched diets may be a model of nonalcoholic steatohepatitis. Molecular and Cellular Biochemistry 268:53-58.
-
(2005)
Molecular and Cellular Biochemistry
, vol.268
, pp. 53-58
-
-
Tous, M.1
Ferré, N.2
Camps, J.3
Riu, F.4
Joven, J.5
-
44
-
-
0034671526
-
The farnesoid X-activated receptor mediates bile acid activation of phospholipid transfer protein gene expression
-
Urizar NL, Dowhan DH, and Moore DD (2000) The farnesoid X-activated receptor mediates bile acid activation of phospholipid transfer protein gene expression. J Biol Chem 275:39313-39317.
-
(2000)
J Biol Chem
, vol.275
, pp. 39313-39317
-
-
Urizar, N.L.1
Dowhan, D.H.2
Moore, D.D.3
-
45
-
-
0033026760
-
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
-
Wang H, Chen J, Hollister K, Sowers LC, and Forman BM (1999) Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol Cell 3:543-553.
-
(1999)
Mol Cell
, vol.3
, pp. 543-553
-
-
Wang, H.1
Chen, J.2
Hollister, K.3
Sowers, L.C.4
Forman, B.M.5
-
46
-
-
85047694456
-
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, andSREBP-1c
-
Watanabe M, Houten SM, Wang L, Moschetta A, Mangelsdorf DJ, Heyman RA, Moore DD, and Auwerx J (2004) Bile acids lower triglyceride levels via a pathway involving FXR, SHP, andSREBP-1c. J Clin Invest 113:1408-1418.
-
(2004)
J Clin Invest
, vol.113
, pp. 1408-1418
-
-
Watanabe, M.1
Houten, S.M.2
Wang, L.3
Moschetta, A.4
Mangelsdorf, D.J.5
Heyman, R.A.6
Moore, D.D.7
Auwerx, J.8
-
47
-
-
0029829455
-
Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
-
Weltman MD, Farrell GC, and Liddle C (1996) Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gas-troenterology 111:1645-1653.
-
(1996)
Gas-troenterology
, vol.111
, pp. 1645-1653
-
-
Weltman, M.D.1
Farrell, G.C.2
Liddle, C.3
-
48
-
-
49649110937
-
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
-
Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, Lütjohann D, Kerksiek A, van Kruchten R, Maeda N, Staels B, et al. (2008) Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology 48:474-486.
-
(2008)
Hepatology
, vol.48
, pp. 474-486
-
-
Wouters, K.1
van Gorp, P.J.2
Bieghs, V.3
Gijbels, M.J.4
Duimel, H.5
Lütjohann, D.6
Kerksiek, A.7
van Kruchten, R.8
Maeda, N.9
Staels, B.10
-
49
-
-
10644243603
-
Induction of macrophage scavenger receptor MARCO in nonalcoholic steatohepatitis indicates possible involvement of endotoxin in its pathogenic process
-
Yoshimatsu M, Terasaki Y, Sakashita N, Kiyota E, Sato H, van der Laan LJ, and Takeya M (2004) Induction of macrophage scavenger receptor MARCO in nonalcoholic steatohepatitis indicates possible involvement of endotoxin in its pathogenic process. Int J Exp Pathol 85:335-343.
-
(2004)
Int J Exp Pathol
, vol.85
, pp. 335-343
-
-
Yoshimatsu, M.1
Terasaki, Y.2
Sakashita, N.3
Kiyota, E.4
Sato, H.5
van der Laan, L.J.6
Takeya, M.7
|