Aryl hydrocarbon receptor-mediated induction of stearoyl-coa Desaturase 1 alters hepatic fatty acid composition in TCDD-elicited steatosis

Toxicological Sciences

Volumn 124, Issue 2, 2011, Pages 299-310

  Angrish, Michelle M ^a   Jones, A D ^a,b   Harkema, Jack R ^a   Zacharewski, Timothy R ^a,b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Michigan State University   (United States)

Author keywords

2,3,7,8 tetrachlorodibenzo dioxin; Liver; Monounsaturated fatty acid; Polyunsaturated fatty acid; Saturated fatty acid; Stearoyl coa desaturase 1; Steatosis

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ACYL COENZYME A DESATURASE 1; ALANINE AMINOTRANSFERASE; AROMATIC HYDROCARBON RECEPTOR; MESSENGER RNA; MONOUNSATURATED FATTY ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; TRIACYLGLYCEROL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL VACUOLE; CHROMATIN IMMUNOPRECIPITATION; FATTY ACID SYNTHESIS; FATTY LIVER; GAS CHROMATOGRAPHY; GENE EXPRESSION; HISTOPATHOLOGY; LIPID COMPOSITION; LIPID METABOLISM; LIPID TRANSPORT; LIVER TOXICITY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PROTEIN INDUCTION; RECEPTOR BINDING;

ANIMALS; BLOTTING, WESTERN; DRUG-INDUCED LIVER INJURY; FATTY ACIDS; FATTY LIVER; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LIVER; MICE; MICE, KNOCKOUT; PRINCIPAL COMPONENT ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ARYL HYDROCARBON; RESPONSE ELEMENTS; STEAROYL-COA DESATURASE; TETRACHLORODIBENZODIOXIN; TRIGLYCERIDES;

EID: 81855211092     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr226     Document Type: Article

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