Poly ic triggers a cathepsin d- and ips-1-dependent pathway to enhance cytokine production and mediate dendritic cell necroptosis

Immunity

Volumn 38, Issue 4, 2013, Pages 717-728

  Zou, Jian ^a,b   Kawai, Taro ^a,b,f   Tsuchida, Tetsuo ^a,b,c   Kozaki, Tatsuya ^a,b   Tanaka, Hiroki ^a,b   Shin, Kyung Sue ^a,b,d   Kumar, Himanshu ^a,b,e   Akira, Shizuo ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c YAMAGATA UNIVERSITY   (Japan)

^d Jeju National University   (South Korea)

^e INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH BHOPAL   (India)

^f NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CASPASE 8; CATHEPSIN D; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON BETA PROMOTER STIMULATOR PROTEIN 1; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOPLASM; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYSOSOME; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CATHEPSIN D; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; GTPASE-ACTIVATING PROTEINS; HMGB1 PROTEIN; IMMUNITY, INNATE; IMMUNOMODULATION; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; NECROSIS; POLY I-C; PROTEIN BINDING; SIGNAL TRANSDUCTION;

EID: 84876767925     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2012.12.007     Document Type: Article

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