Double-stranded RNA-mediated TLR3 activation is enhanced by CD14

Immunity

Volumn 24, Issue 2, 2006, Pages 153-163

  Lee, Hyun Ku ^a   Dunzendorfer, Stefan ^a   Soldau, Katrin ^a   Tobias, Peter S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; DOUBLE STRANDED RNA; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CELL STIMULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; ENDOSOME; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; LYSOSOME; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD14; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; CYTOPLASMIC VESICLES; HUMANS; MACROPHAGES; MICE; MICE, KNOCKOUT; NF-KAPPA B; PHOSPHATIDYLCHOLINES; RNA, DOUBLE-STRANDED; TOLL-LIKE RECEPTOR 3; TRANSFECTION;

EID: 32244432768     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.12.012     Document Type: Article

References (37)

1. L. Alexopoulou, A.C. Holt, R. Medzhitov, and R.A. Flavell Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3 Nature 413 2001 732 738
2. A.O. Aliprantis, R.B. Yang, M.R. Mark, S. Suggett, B. Devaux, J.D. Radolf, G.R. Klimpel, P. Godowski, and A. Zychlinsky Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2 Science 285 1999 736 739
3. B. Beutler Inferences, questions and possibilities in Toll-like receptor signaling Nature 430 2004 257 263
4. W.A. Carter, and E. De Clercq Viral infection and host defense Science 186 1974 1172 1178
5. A. Celada, P.W. Gray, E. Rinderknecht, and R.D. Schreiber Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity J. Exp. Med. 160 1984 55 74
6. S. Dunzendorfer, H.-K. Lee, K. Soldau, and P.S. Tobias TLR4 is the signaling but not the lipopolysaccharide uptake receptor J. Immunol. 173 2004 1166 1170
7. S. Dunzendorfer, H.-K. Lee, K. Soldau, and P.S. Tobias Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses FASEB J. 18 2004 1117 1119
8. R. Dziarski, R.I. Tapping, and P.S. Tobias Binding of bacterial peptidoglycan to CD14 J. Biol. Chem. 273 1998 8680 8690
9. R. Dziarski, A. Ulmer, and D. Gupta Interactions of CD14 with components of Gram-positive bacteria Chem. Immunol. 74 2000 83 107
10. J.A. Gegner, R.J. Ulevitch, and P.S. Tobias Lipopolysaccharide (LPS) signal transduction and clearance J. Biol. Chem. 270 1995 5320 5325
11. H. Häcker, H. Mischak, T. Miethke, S. Liptay, R. Schmid, T. Sparwasser, K. Heeg, G.B. Lipford, and H. Wagner CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation EMBO J. 17 1998 6230 6240
12. E. Hailman, H.S. Lichenstein, M.M. Wurfel, D.S. Miller, D.A. Johnson, M. Kelley, L.A. Busse, M.M. Zukowski, and S.D. Wright Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14 J. Exp. Med. 179 1994 269 277
13. F. Hayashi, K.D. Smith, A. Ozinsky, T.R. Hawn, E.C. Yi, D.R. Goodlett, J.K. Eng, S. Akira, D.M. Underhill, and A. Aderem The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 Nature 410 2001 1099 1103
14. F. Heil, H. Hemmi, H. Hochrein, F. Ampenberger, C. Kirschning, S. Akira, G. Lipford, H. Wagner, and S. Bauer Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8 Science 303 2004 1526 1529
15. H. Hemmi, O. Takeuchi, T. Kawai, T. Kaisho, S. Sato, H. Sanjo, M. Matsumoto, K. Hoshino, H. Wagner, K. Takeda, and S. Akira A Toll-like receptor recognizes bacterial DNA Nature 408 2000 740 745
16. J.I. Kim, C.J. Lee, M.S. Jin, C.H. Lee, S.G. Paik, H. Lee, and J.O. Lee Crystal structure of CD14 and its implications for lipopolysaccharide signaling J. Biol. Chem. 280 2005 11347 11351
17. T.N. Kirkland, F. Finley, D. Leturcq, A. Moriarty, J.-D. Lee, R.J. Ulevitch, and P.S. Tobias Analysis of lipopolysaccharide binding by CD14 J. Biol. Chem. 268 1993 24818 24823
18. E. Latz, A. Schoenemeyer, A. Visintin, K.A. Fitzgerald, B.G. Monks, C.F. Knetter, E. Lien, N.J. Nilsen, T. Espevik, and D.T. Golenbock TLR9 signals after translocating from the ER to CpG DNA in the lysosome Nat. Immunol. 5 2004 190 198
19. H.-K. Lee, J. Lee, and P.S. Tobias Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signaling J. Immunol. 168 2002 4012 4017
20. C.A. Leifer, M.N. Kennedy, A. Mazzoni, C.W. Lee, M.J. Kruhlak, and D.M. Segal TLR9 is localized in the endoplasmic reticulum prior to stimulation J. Immunol. 173 2004 1179 1183
21. J.P. Luzio, B.M. Mullock, P.R. Pryor, M.R. Lindsay, D.E. James, and R.C. Piper Relationship between endosomes and lysosomes Biochem. Soc. Trans. 29 2001 476 480
22. J.A. Majde Viral double-stranded RNA, cytokines, and the flu J. Interferon Cytokine Res. 20 2001 259 272
23. M. Matsumoto, K. Funami, M. Tanabe, H. Oshiumi, M. Shingai, Y. Seto, A. Yamamoto, and T. Seya Subcellular localization of Toll-like receptor 3 in human dendritic cells J. Immunol. 171 2003 3154 3162
24. R. Medzhitov, and C.A. Janeway Jr. Innate immunity N. Engl. J. Med. 343 2000 338 344
25. R. Medzhitov, P. Preston-Hurlburt, and C.A. Janeway Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity Nature 388 1997 394 397
26. A. Poltorak, X. He, I. Smirnova, M.-Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, and C. Galanos Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene Science 282 1998 2085 2088
27. J. Pugin, D.A. Heumann, A. Tomasz, V.V. Kravchenko, Y. Akamatsu, M. Nishijima, M.P. Glauser, P.S. Tobias, and R.J. Ulevitch CD14 is a pattern recognition receptor Immunity 1 1994 509 516
28. M. Rutz, J. Metzger, T. Gellert, P. Luppa, G.B. Lipford, H. Wagner, and S. Bauer Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner Eur. J. Immunol. 34 2004 2541 2550
29. R.I. Tapping, and P.S. Tobias Cellular binding of soluble CD14 requires lipopolysaccharide (LPS) and LPS-binding protein J. Biol. Chem. 272 1997 23157 23164
30. P.S. Tobias, K. Soldau, L. Kline, J.-D. Lee, K.J. Kato, T.R. Martin, and R.J. Ulevitch Cross-linking of lipopolysaccharide (LPS) to CD14 on THP-1 cells mediated by LPS-binding protein J. Immunol. 150 1993 3011 3021
31. P.S. Tobias, K. Soldau, J.A. Gegner, D. Mintz, and R.J. Ulevitch Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14 J. Biol. Chem. 270 1995 10482 10488
32. R.J. Ulevitch Therapeutics targeting the innate immune system Nat. Rev. Immunol. 4 2004 512 520
33. D.M. Underhill, A. Ozinsky, A.M. Hajjar, A. Stevens, C.B. Wilson, M. Bassetti, and A. Aderem The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens Nature 401 1999 811 815
34. T. Vasselon, P.A. Detmers, D. Charron, and A. Haziot TLR2 recognizes a bacterial lipopeptide through direct binding J. Immunol. 173 2004 7401 7405
35. P. Wang, and R.S. Munford CD14-dependent internalization and metabolism of extracellular phosphatidylinositol by monocytes J. Biol. Chem. 274 1999 23235 23241
36. P.Y. Wang, R.L. Kitchens, and R.S. Munford Phosphatidylinositides bind to plasma membrane CD14 and can prevent monocyte activation by bacterial lipopolysaccharide J. Biol. Chem. 273 1998 24309 24313
37. S.D. Wright, R.A. Ramos, P.S. Tobias, R.J. Ulevitch, and J.C. Mathison CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein Science 249 1990 1431 1433