SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8+ T cells

Immunologic Research

Volumn 55, Issue 1-3, 2013, Pages 116-124

  Friend, Samantha F ^a,b   Peterson, Lisa K ^a   Kedl, Ross M ^b   Dragone, Leonard L ^a,b,c  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c CHILDREN S HOSPITAL COLORADO   (United States)

Author keywords

CD8+ T cells; SLAP; TCR chain repertoire; TCR avidity

Indexed keywords

ADAPTOR PROTEIN; CD5 ANTIGEN; OVALBUMIN; SLAP PROTEIN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; TETRAMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CD8+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SPLEEN CELL; STAINING; TRANSGENE;

ANIMALS; ANTIGENS; CD8-POSITIVE T-LYMPHOCYTES; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECEPTORS, ANTIGEN, T-CELL;

EID: 84876716770     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-012-8354-y     Document Type: Article

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