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Volumn 22, Issue 5, 2010, Pages 287-293

Role of thymic cortex-specific self-peptides in positive selection of T cells

Author keywords

Positive selection; Thymic cortical epithelial cell; Thymoproteasome

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN; PROTEASOME; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

EID: 77955985022     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smim.2010.04.012     Document Type: Review
Times cited : (54)

References (88)
  • 1
    • 0023819187 scopus 로고
    • Developmental status and reconstitution potential of subpopulations of murine thymocytes
    • Scollay R., Wilson A., D'Amico A., Kelly K., Egerton M., Pearse M., et al. Developmental status and reconstitution potential of subpopulations of murine thymocytes. Immunol Rev 1988, 104:81-120.
    • (1988) Immunol Rev , vol.104 , pp. 81-120
    • Scollay, R.1    Wilson, A.2    D'Amico, A.3    Kelly, K.4    Egerton, M.5    Pearse, M.6
  • 2
    • 0037036140 scopus 로고    scopus 로고
    • Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy
    • Bousso P., Bhakta N.R., Lewis R.S., Robey E. Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy. Science 2002, 296:1876-1880.
    • (2002) Science , vol.296 , pp. 1876-1880
    • Bousso, P.1    Bhakta, N.R.2    Lewis, R.S.3    Robey, E.4
  • 3
    • 34548612228 scopus 로고    scopus 로고
    • Noninvasive intravital imaging of thymocyte dynamics in medaka
    • Li J., Iwanami N., Hoa V.Q., Furutani-Seiki M., Takahama Y. Noninvasive intravital imaging of thymocyte dynamics in medaka. J Immunol 2007, 179:1605-1615.
    • (2007) J Immunol , vol.179 , pp. 1605-1615
    • Li, J.1    Iwanami, N.2    Hoa, V.Q.3    Furutani-Seiki, M.4    Takahama, Y.5
  • 7
    • 0028294682 scopus 로고
    • Positive and negative thymocyte selection induced by different concentrations of a single peptide
    • Sebzda E., Wallace V.A., Mayer J., Yeung R.S., Mak T.W., Ohashi P.S. Positive and negative thymocyte selection induced by different concentrations of a single peptide. Science 1994, 263:1615-1618.
    • (1994) Science , vol.263 , pp. 1615-1618
    • Sebzda, E.1    Wallace, V.A.2    Mayer, J.3    Yeung, R.S.4    Mak, T.W.5    Ohashi, P.S.6
  • 10
    • 0023683669 scopus 로고
    • Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
    • Kisielow P., Teh H.S., Blüthmann H., von Boehmer H. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 1988, 335:730-733.
    • (1988) Nature , vol.335 , pp. 730-733
    • Kisielow, P.1    Teh, H.S.2    Blüthmann, H.3    von Boehmer, H.4
  • 11
    • 0028032155 scopus 로고
    • Positive selection of lymphocytes
    • von Boehmer H. Positive selection of lymphocytes. Cell 1994, 76:219-228.
    • (1994) Cell , vol.76 , pp. 219-228
    • von Boehmer, H.1
  • 12
    • 0028208488 scopus 로고
    • Peptides in positive and negative selection: a delicate balance
    • Allen P.M. Peptides in positive and negative selection: a delicate balance. Cell 1994, 76:593-596.
    • (1994) Cell , vol.76 , pp. 593-596
    • Allen, P.M.1
  • 14
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • Kappler J.W., Roehm N., Marrack P. T cell tolerance by clonal elimination in the thymus. Cell 1987, 49:273-280.
    • (1987) Cell , vol.49 , pp. 273-280
    • Kappler, J.W.1    Roehm, N.2    Marrack, P.3
  • 15
    • 0038725685 scopus 로고    scopus 로고
    • Negative selection-clearing out the bad apples from the T-cell repertoire
    • Palmer E. Negative selection-clearing out the bad apples from the T-cell repertoire. Nat Rev Immunol 2003, 3:383-391.
    • (2003) Nat Rev Immunol , vol.3 , pp. 383-391
    • Palmer, E.1
  • 17
    • 0028054017 scopus 로고
    • T-cell apoptosis detected in situ during positive and negative selection in the thymus
    • Surh C.D., Sprent J. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 1994, 372:100-103.
    • (1994) Nature , vol.372 , pp. 100-103
    • Surh, C.D.1    Sprent, J.2
  • 18
    • 0035171545 scopus 로고    scopus 로고
    • Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
    • Derbinski J., Schulte A., Kyewski B., Klein L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat Immunol 2001, 2:1032-1039.
    • (2001) Nat Immunol , vol.2 , pp. 1032-1039
    • Derbinski, J.1    Schulte, A.2    Kyewski, B.3    Klein, L.4
  • 19
    • 7244227645 scopus 로고    scopus 로고
    • Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
    • Gallegos A.M., Bevan M.J. Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation. J Exp Med 2004, 200:1039-1049.
    • (2004) J Exp Med , vol.200 , pp. 1039-1049
    • Gallegos, A.M.1    Bevan, M.J.2
  • 20
    • 14944348965 scopus 로고    scopus 로고
    • The role of BH3-only proteins in the immune system
    • Strasser A. The role of BH3-only proteins in the immune system. Nat Rev Immunol 2005, 5:189-200.
    • (2005) Nat Rev Immunol , vol.5 , pp. 189-200
    • Strasser, A.1
  • 21
    • 33644636553 scopus 로고    scopus 로고
    • The why and how of thymocyte negative selection
    • Siggs O.M., Makaroff L.E., Liston A. The why and how of thymocyte negative selection. Curr Opin Immunol 2006, 18:175-183.
    • (2006) Curr Opin Immunol , vol.18 , pp. 175-183
    • Siggs, O.M.1    Makaroff, L.E.2    Liston, A.3
  • 22
    • 0017688347 scopus 로고
    • In a radiation chimaera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells
    • Bevan M.J. In a radiation chimaera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells. Nature 1977, 269:417-418.
    • (1977) Nature , vol.269 , pp. 417-418
    • Bevan, M.J.1
  • 23
    • 0018085532 scopus 로고
    • On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?
    • Zinkernagel R.M., Callahan G.N., Althage A., Cooper S., Klein P.A., Klein J. On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?. J Exp Med 1978, 147:882-896.
    • (1978) J Exp Med , vol.147 , pp. 882-896
    • Zinkernagel, R.M.1    Callahan, G.N.2    Althage, A.3    Cooper, S.4    Klein, P.A.5    Klein, J.6
  • 24
    • 0026030196 scopus 로고
    • ++ thymocytes as post-selection intermediates leading to mature T cells
    • ++ thymocytes as post-selection intermediates leading to mature T cells. J Exp Med 1991, 173:323-332.
    • (1991) J Exp Med , vol.173 , pp. 323-332
    • Shortman, K.1    Vremec, D.2    Egerton, M.3
  • 25
    • 0025933951 scopus 로고
    • Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
    • Huesmann M., Scott B., Kisielow P., von Boehmer H. Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell 1991, 66:533-540.
    • (1991) Cell , vol.66 , pp. 533-540
    • Huesmann, M.1    Scott, B.2    Kisielow, P.3    von Boehmer, H.4
  • 26
    • 0030935007 scopus 로고    scopus 로고
    • The MHC reactivity of the T cell repertoire prior to positive and negative selection
    • Zerrahn J., Held W., Raulet D.H. The MHC reactivity of the T cell repertoire prior to positive and negative selection. Cell 1997, 88:627-636.
    • (1997) Cell , vol.88 , pp. 627-636
    • Zerrahn, J.1    Held, W.2    Raulet, D.H.3
  • 30
    • 67349280397 scopus 로고    scopus 로고
    • Germline-encoded amino acids in the αβ T-cell receptor control thymic selection
    • Scott-Browne J.P., White J., Kappler J.W., Gapin L., Marrack P. Germline-encoded amino acids in the αβ T-cell receptor control thymic selection. Nature 2009, 458:1043-1046.
    • (2009) Nature , vol.458 , pp. 1043-1046
    • Scott-Browne, J.P.1    White, J.2    Kappler, J.W.3    Gapin, L.4    Marrack, P.5
  • 31
    • 0030966756 scopus 로고    scopus 로고
    • Positive selection of thymocytes bearing αβ T cell receptors
    • Marrack P., Kappler J. Positive selection of thymocytes bearing αβ T cell receptors. Curr Opin Immunol 1997, 9:250-255.
    • (1997) Curr Opin Immunol , vol.9 , pp. 250-255
    • Marrack, P.1    Kappler, J.2
  • 32
    • 22744441535 scopus 로고    scopus 로고
    • How the T cell repertoire becomes peptide and MHC specific
    • Huseby E.S., White J., Crawford F., Vass T., Becker D., Pinilla C., et al. How the T cell repertoire becomes peptide and MHC specific. Cell 2005, 122:247-260.
    • (2005) Cell , vol.122 , pp. 247-260
    • Huseby, E.S.1    White, J.2    Crawford, F.3    Vass, T.4    Becker, D.5    Pinilla, C.6
  • 33
    • 40249118205 scopus 로고    scopus 로고
    • Crossreactive T cells spotlight the germline rules for αβ T cell-receptor interactions with MHC molecules
    • Dai S., Huseby E.S., Rubtsova K., Scott-Browne J., Crawford F., Macdonald W.A., et al. Crossreactive T cells spotlight the germline rules for αβ T cell-receptor interactions with MHC molecules. Immunity 2008, 28:324-334.
    • (2008) Immunity , vol.28 , pp. 324-334
    • Dai, S.1    Huseby, E.S.2    Rubtsova, K.3    Scott-Browne, J.4    Crawford, F.5    Macdonald, W.A.6
  • 34
    • 34848813147 scopus 로고    scopus 로고
    • Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains
    • Huseby E.S., Kappler J.W., Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Mol Immunol 2008, 45:599-606.
    • (2008) Mol Immunol , vol.45 , pp. 599-606
    • Huseby, E.S.1    Kappler, J.W.2    Marrack, P.3
  • 35
    • 0003021556 scopus 로고
    • Role of self antigen in the selection of the developing T cell repertoire
    • Singer A., Mizuochi T., Munitz T.I., Gress R.E. Role of self antigen in the selection of the developing T cell repertoire. Prog Immunol 1986, 6:60-66.
    • (1986) Prog Immunol , vol.6 , pp. 60-66
    • Singer, A.1    Mizuochi, T.2    Munitz, T.I.3    Gress, R.E.4
  • 36
    • 0025021670 scopus 로고
    • Role of self-peptides in positively selecting the T-cell repertoire
    • Nikolic-Zugic J., Bevan M.J. Role of self-peptides in positively selecting the T-cell repertoire. Nature 1990, 344:65-67.
    • (1990) Nature , vol.344 , pp. 65-67
    • Nikolic-Zugic, J.1    Bevan, M.J.2
  • 40
    • 0025886546 scopus 로고
    • Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes
    • Brown M.G., Driscoll J., Monaco J.J. Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes. Nature 1991, 353:355-357.
    • (1991) Nature , vol.353 , pp. 355-357
    • Brown, M.G.1    Driscoll, J.2    Monaco, J.J.3
  • 41
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock K.L., Gramm C., Rothstein L., Clark K., Stein R., Dick L., et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 1994, 78:761-771.
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.L.1    Gramm, C.2    Rothstein, L.3    Clark, K.4    Stein, R.5    Dick, L.6
  • 42
    • 0032488846 scopus 로고    scopus 로고
    • The proteasome: paradigm of a self-compartmentalizing protease
    • Baumeister W., Walz J., Zuhl F., Seemuller E. The proteasome: paradigm of a self-compartmentalizing protease. Cell 1998, 92:367-380.
    • (1998) Cell , vol.92 , pp. 367-380
    • Baumeister, W.1    Walz, J.2    Zuhl, F.3    Seemuller, E.4
  • 43
    • 0028000102 scopus 로고
    • Role of proteasomes modified by interferon-gamma in antigen processing
    • Tanaka K. Role of proteasomes modified by interferon-gamma in antigen processing. J Leukoc Biol 1994, 56:571-575.
    • (1994) J Leukoc Biol , vol.56 , pp. 571-575
    • Tanaka, K.1
  • 44
    • 0032971227 scopus 로고    scopus 로고
    • Degradation of cell proteins and the generation of MHC class I-presented peptides
    • Rock K.L., Goldberg A.L. Degradation of cell proteins and the generation of MHC class I-presented peptides. Annu Rev Immunol 1999, 17:739-779.
    • (1999) Annu Rev Immunol , vol.17 , pp. 739-779
    • Rock, K.L.1    Goldberg, A.L.2
  • 45
    • 67149117118 scopus 로고    scopus 로고
    • Exclusive expression of proteasome subunit β5t in the human thymic cortex
    • Tomaru U., Ishizu A., Murata S., Miyatake Y., Suzuki S., Takahashi S., et al. Exclusive expression of proteasome subunit β5t in the human thymic cortex. Blood 2009, 113:5186-5191.
    • (2009) Blood , vol.113 , pp. 5186-5191
    • Tomaru, U.1    Ishizu, A.2    Murata, S.3    Miyatake, Y.4    Suzuki, S.5    Takahashi, S.6
  • 46
    • 0037242017 scopus 로고    scopus 로고
    • Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I
    • Reits E., Griekspoor A., Neijssen J., Groothuis T., Jalink K., van Veelen P., et al. Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity 2003, 18:97-108.
    • (2003) Immunity , vol.18 , pp. 97-108
    • Reits, E.1    Griekspoor, A.2    Neijssen, J.3    Groothuis, T.4    Jalink, K.5    van Veelen, P.6
  • 47
    • 0346521283 scopus 로고    scopus 로고
    • Making sense of mass destruction: quantitating MHC class I antigen presentation
    • Yewdell J.W., Reits E., Neefjes J. Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat Rev Immunol 2003, 3:952-961.
    • (2003) Nat Rev Immunol , vol.3 , pp. 952-961
    • Yewdell, J.W.1    Reits, E.2    Neefjes, J.3
  • 48
    • 0025855156 scopus 로고
    • Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
    • Falk K., Rotzschke, Stevanovic S., Jung G., Rammensee H.R. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991, 351:290-296.
    • (1991) Nature , vol.351 , pp. 290-296
    • Falk, K.1    Rotzschke2    Stevanovic, S.3    Jung, G.4    Rammensee, H.R.5
  • 49
    • 0026507564 scopus 로고
    • Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry
    • Hunt D.F., Henderson R.A., Shabanowitz J., Sakaguchi K., Michel H., Sevilir N., et al. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science 1992, 255:1261-1263.
    • (1992) Science , vol.255 , pp. 1261-1263
    • Hunt, D.F.1    Henderson, R.A.2    Shabanowitz, J.3    Sakaguchi, K.4    Michel, H.5    Sevilir, N.6
  • 50
    • 0028887622 scopus 로고
    • Structural studies of class I major histocompatibility complex proteins: insights into antigen presentation
    • Young A.C., Nathenson S.G., Sacchettini J.C. Structural studies of class I major histocompatibility complex proteins: insights into antigen presentation. FASEB J 1995, 9:26-36.
    • (1995) FASEB J , vol.9 , pp. 26-36
    • Young, A.C.1    Nathenson, S.G.2    Sacchettini, J.C.3
  • 51
    • 0027991677 scopus 로고
    • MHC class I expression in mice lacking the proteasome subunit LMP-7
    • Fehling H.J., Swat W., Laplace C., Kühn R., Rajewsky K., Müller U., et al. MHC class I expression in mice lacking the proteasome subunit LMP-7. Science 1994, 265:1234-1237.
    • (1994) Science , vol.265 , pp. 1234-1237
    • Fehling, H.J.1    Swat, W.2    Laplace, C.3    Kühn, R.4    Rajewsky, K.5    Müller, U.6
  • 53
    • 0030850034 scopus 로고    scopus 로고
    • Recognition principle of the TAP transporter disclosed by combinatorial peptide libraries
    • Uebel S., Kraas W., Kienle S., Wiesmüller K.H., Jung G., Tampé R. Recognition principle of the TAP transporter disclosed by combinatorial peptide libraries. Proc Natl Acad Sci USA 1997, 94:8976-8981.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8976-8981
    • Uebel, S.1    Kraas, W.2    Kienle, S.3    Wiesmüller, K.H.4    Jung, G.5    Tampé, R.6
  • 56
    • 0030849769 scopus 로고    scopus 로고
    • Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody
    • Porgador A., Yewdell J.W., Deng Y., Bennink J.R., Germain R.N. Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity 1997, 6:715-726.
    • (1997) Immunity , vol.6 , pp. 715-726
    • Porgador, A.1    Yewdell, J.W.2    Deng, Y.3    Bennink, J.R.4    Germain, R.N.5
  • 57
    • 57649165426 scopus 로고    scopus 로고
    • How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide
    • Mareeva T., Martinez-Hackert E., Sykulev Y. How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide. J Biol Chem 2008, 283:29053-29059.
    • (2008) J Biol Chem , vol.283 , pp. 29053-29059
    • Mareeva, T.1    Martinez-Hackert, E.2    Sykulev, Y.3
  • 58
    • 32244432265 scopus 로고    scopus 로고
    • CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance
    • Kurobe H., Liu C., Ueno T., Saito F., Ohigashi I., Seach N., et al. CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. Immunity 2006, 24:165-177.
    • (2006) Immunity , vol.24 , pp. 165-177
    • Kurobe, H.1    Liu, C.2    Ueno, T.3    Saito, F.4    Ohigashi, I.5    Seach, N.6
  • 59
    • 70350131707 scopus 로고    scopus 로고
    • CCR7-mediated medulla migration of developing thymocytes is essential for negative selection to tissue-restricted antigens
    • Nitta T., Nitta S., Lei Y., Lipp M., Takahama Y. CCR7-mediated medulla migration of developing thymocytes is essential for negative selection to tissue-restricted antigens. Proc Natl Acad Sci USA 2009, 106:17129-17133.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 17129-17133
    • Nitta, T.1    Nitta, S.2    Lei, Y.3    Lipp, M.4    Takahama, Y.5
  • 60
    • 72849115174 scopus 로고    scopus 로고
    • Origin and evolution of the adaptive immune system: genetic events and selective pressures
    • Martin F., Flajnik M.F., Kasahara M. Origin and evolution of the adaptive immune system: genetic events and selective pressures. Nat Rev Genet 2010, 11:47-59.
    • (2010) Nat Rev Genet , vol.11 , pp. 47-59
    • Martin, F.1    Flajnik, M.F.2    Kasahara, M.3
  • 61
    • 65449154084 scopus 로고    scopus 로고
    • The adaptive phenotype of cortical thymic epithelial cells
    • Boehm T. The adaptive phenotype of cortical thymic epithelial cells. Eur J Immunol 2009, 39:944-947.
    • (2009) Eur J Immunol , vol.39 , pp. 944-947
    • Boehm, T.1
  • 62
    • 0030058657 scopus 로고    scopus 로고
    • The repertoire of T cells shaped by a single MHC/peptide ligand
    • Ignatowicz L., Kappler J., Marrack P. The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 1996, 84:521-529.
    • (1996) Cell , vol.84 , pp. 521-529
    • Ignatowicz, L.1    Kappler, J.2    Marrack, P.3
  • 63
    • 0030996826 scopus 로고    scopus 로고
    • + thymocyte selection by a single MHC class II/peptide ligand affected by its expression level in the thymus
    • + thymocyte selection by a single MHC class II/peptide ligand affected by its expression level in the thymus. Immunity 1997, 6:401-410.
    • (1997) Immunity , vol.6 , pp. 401-410
    • Fukui, Y.1    Ishimoto, T.2    Utsuyama, M.3    Gyotoku, T.4    Koga, T.5    Nakao, K.6
  • 64
    • 70449376996 scopus 로고    scopus 로고
    • A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire
    • Wang B., Primeau T.M., Myers N., Rohrs H.W., Gross M.L., Lybarger L., et al. A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire. Science 2009, 326:871-874.
    • (2009) Science , vol.326 , pp. 871-874
    • Wang, B.1    Primeau, T.M.2    Myers, N.3    Rohrs, H.W.4    Gross, M.L.5    Lybarger, L.6
  • 65
    • 0027162178 scopus 로고
    • Positive selection of T lymphocytes on fibroblasts
    • Pawlowski T., Elliott J.D., Loh D.Y., Staerz U.D. Positive selection of T lymphocytes on fibroblasts. Nature 1993, 364:642-645.
    • (1993) Nature , vol.364 , pp. 642-645
    • Pawlowski, T.1    Elliott, J.D.2    Loh, D.Y.3    Staerz, U.D.4
  • 67
    • 0033529213 scopus 로고    scopus 로고
    • On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells
    • Zinkernagel R.M., Althage A. On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells. Proc Natl Acad Sci USA 1999, 96:8092-8097.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8092-8097
    • Zinkernagel, R.M.1    Althage, A.2
  • 68
    • 0037452706 scopus 로고    scopus 로고
    • Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC
    • Martinic M.M., Rülicke T., Althage A., Odermatt B., Höchli M., Lamarre A., et al. Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC. Proc Natl Acad Sci USA 2003, 100:1861-1866.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1861-1866
    • Martinic, M.M.1    Rülicke, T.2    Althage, A.3    Odermatt, B.4    Höchli, M.5    Lamarre, A.6
  • 69
    • 26644473419 scopus 로고    scopus 로고
    • Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells
    • Choi E.Y., Jung K.C., Park H.J., Chung D.H., Song J.S., Yang S.D., et al. Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells. Immunity 2005, 23:387-396.
    • (2005) Immunity , vol.23 , pp. 387-396
    • Choi, E.Y.1    Jung, K.C.2    Park, H.J.3    Chung, D.H.4    Song, J.S.5    Yang, S.D.6
  • 70
    • 26644471257 scopus 로고    scopus 로고
    • An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population
    • Li W., Kim M.G., Gourley T.S., McCarthy B.P., Sant'Angelo D.B., Chang C.H. An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population. Immunity 2005, 23:375-386.
    • (2005) Immunity , vol.23 , pp. 375-386
    • Li, W.1    Kim, M.G.2    Gourley, T.S.3    McCarthy, B.P.4    Sant'Angelo, D.B.5    Chang, C.H.6
  • 71
    • 49049087784 scopus 로고    scopus 로고
    • Peripheral T lymphocytes recirculating back into the thymus can mediate thymocyte positive selection
    • Kirberg J., Bosco N., Deloulme J.C., Ceredig R., Agenès F. Peripheral T lymphocytes recirculating back into the thymus can mediate thymocyte positive selection. J Immunol 2008, 181:1207-1214.
    • (2008) J Immunol , vol.181 , pp. 1207-1214
    • Kirberg, J.1    Bosco, N.2    Deloulme, J.C.3    Ceredig, R.4    Agenès, F.5
  • 72
    • 0035210581 scopus 로고    scopus 로고
    • Organ-specific autoimmunity in mice whose T cell repertoire is shaped by a single antigenic peptide
    • Oono T., Fukui Y., Masuko S., Hashimoto O., Ueno T., Sanui T., et al. Organ-specific autoimmunity in mice whose T cell repertoire is shaped by a single antigenic peptide. J Clin Invest 2001, 108:1589-1596.
    • (2001) J Clin Invest , vol.108 , pp. 1589-1596
    • Oono, T.1    Fukui, Y.2    Masuko, S.3    Hashimoto, O.4    Ueno, T.5    Sanui, T.6
  • 73
    • 0033613086 scopus 로고    scopus 로고
    • Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells
    • Zerrahn J., Volkmann A., Coles M.C., Held W., Lemonnieri F.A., Raulet D.H. Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells. Proc Natl Acad Sci USA 1999, 96:11470-11475.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11470-11475
    • Zerrahn, J.1    Volkmann, A.2    Coles, M.C.3    Held, W.4    Lemonnieri, F.A.5    Raulet, D.H.6
  • 76
    • 0032540474 scopus 로고    scopus 로고
    • Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus
    • Nakagawa T., Roth W., Wong P., Nelson A., Farr A., Deussing J., et al. Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus. Science 1998, 280:450-453.
    • (1998) Science , vol.280 , pp. 450-453
    • Nakagawa, T.1    Roth, W.2    Wong, P.3    Nelson, A.4    Farr, A.5    Deussing, J.6
  • 77
    • 0037141021 scopus 로고    scopus 로고
    • + T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands
    • + T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands. J Exp Med 2002, 195:1349-1358.
    • (2002) J Exp Med , vol.195 , pp. 1349-1358
    • Honey, K.1    Nakagawa, T.2    Peters, C.3    Rudensky, A.4
  • 79
    • 52149099867 scopus 로고    scopus 로고
    • Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
    • Nedjic J., Aichinger M., Emmerich J., Mizushima N., Klein L. Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 2008, 455:396-400.
    • (2008) Nature , vol.455 , pp. 396-400
    • Nedjic, J.1    Aichinger, M.2    Emmerich, J.3    Mizushima, N.4    Klein, L.5
  • 80
    • 64049084637 scopus 로고    scopus 로고
    • Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules
    • Nedjic J., Aichinger M., Mizushima N., Klein L. Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules. Curr Opin Immunol 2009, 21:92-97.
    • (2009) Curr Opin Immunol , vol.21 , pp. 92-97
    • Nedjic, J.1    Aichinger, M.2    Mizushima, N.3    Klein, L.4
  • 81
    • 44549088086 scopus 로고    scopus 로고
    • Modest cortex and promiscuous medulla for thymic repertoire formation
    • Takahama Y., Tanaka K., Murata S. Modest cortex and promiscuous medulla for thymic repertoire formation. Trends Immunol 2008, 29:251-255.
    • (2008) Trends Immunol , vol.29 , pp. 251-255
    • Takahama, Y.1    Tanaka, K.2    Murata, S.3
  • 82
    • 44749085669 scopus 로고    scopus 로고
    • Thymoproteasome: probable role in generating positively selecting peptides
    • Murata S., Takahama Y., Tanaka K. Thymoproteasome: probable role in generating positively selecting peptides. Curr Opin Immunol 2008, 20:192-196.
    • (2008) Curr Opin Immunol , vol.20 , pp. 192-196
    • Murata, S.1    Takahama, Y.2    Tanaka, K.3
  • 83
  • 84
    • 72949104779 scopus 로고    scopus 로고
    • Antigen presentation in the thymus for positive selection and central tolerance induction
    • Klein L., Hinterberger M., Wirnsberger G., Kyewski B. Antigen presentation in the thymus for positive selection and central tolerance induction. Nat Rev Immunol 2009, 9:833-844.
    • (2009) Nat Rev Immunol , vol.9 , pp. 833-844
    • Klein, L.1    Hinterberger, M.2    Wirnsberger, G.3    Kyewski, B.4
  • 86
    • 0033180491 scopus 로고    scopus 로고
    • The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
    • Ernst B., Lee D.S., Chang J.M., Sprent J., Surh C.D. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 1999, 11:173-181.
    • (1999) Immunity , vol.11 , pp. 173-181
    • Ernst, B.1    Lee, D.S.2    Chang, J.M.3    Sprent, J.4    Surh, C.D.5
  • 87
    • 70350439671 scopus 로고    scopus 로고
    • An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells
    • Lo W.L., Felix N.J., Walters J.J., Rohrs H., Gross M.L., Allen P.M. An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells. Nat Immunol 2009, 10:1155-1161.
    • (2009) Nat Immunol , vol.10 , pp. 1155-1161
    • Lo, W.L.1    Felix, N.J.2    Walters, J.J.3    Rohrs, H.4    Gross, M.L.5    Allen, P.M.6
  • 88
    • 70350435670 scopus 로고    scopus 로고
    • An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a
    • Ebert P.J., Jiang S., Xie J., Li Q.J., Davis M.M. An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. Nat Immunol 2009, 10:1162-1169.
    • (2009) Nat Immunol , vol.10 , pp. 1162-1169
    • Ebert, P.J.1    Jiang, S.2    Xie, J.3    Li, Q.J.4    Davis, M.M.5


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