Hair as an alternative matrix in bioanalysis

Bioanalysis

Volumn 5, Issue 8, 2013, Pages 895-914

  Barbosa, Joana ^a   Faria, Juliana ^a   Carvalho, Félix ^b   Pedro, Madalena ^a,b   Queirós, Odília ^a,c   Moreira, Roxana ^a,c   Dinis Oliveira, Ricardo Jorge ^a,b,d,e  

^a INSTITUTO DE INVESTIGAÇÃO E FORMAÇÃO AVANÇADA EM CIÊNCIAS E TECNOLOGIAS DA SAÚDE   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF MINHO   (Portugal)

^d University of Porto   (Portugal)

^e CESPU   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 HYDROXYBUTYRIC ACID; 7 AMINOFLUNITRAZEPAM; AMITRIPTYLINE; ANDROSTANOLONE; ANDROSTENEDIOL; ANDROSTENEDIONE; BENZODIAZEPINE; BROMAZEPAM; BUPRENORPHINE; CANNABINOID; COCAINE; CORTICOSTEROID; CYAMEMAZINE; DIGOXIN; FLUNITRAZEPAM; HALOPERIDOL; HYDROXYPROGESTERONE; KETAMINE; LORAZEPAM; MELANIN; MEPROBAMATE; METHADONE; MORPHINE; NICOTINE; OPIATE; PHENCYCLIDINE; PRASTERONE; TESTOSTERONE; UNINDEXED DRUG;

AGE DETERMINATION; ALCOHOL ABUSE; ANALYTIC METHOD; CLONED ENZYME DONOR IMMUNOASSAY; DOPING; DRIVER LICENCE; DRUG ABUSE; DRUG DIFFUSION; DRUG FATALITY; DRUG HAIR LEVEL; DRUG METABOLISM; DRUG MONITORING; ENVIRONMENTAL EXPOSURE; ENZYME MULTIPLIED IMMUNOASSAY TECHNIQUE; ETHNICITY; FLUORESCENCE POLARIZATION IMMUNOASSAY; GAS CHROMATOGRAPHY; HAIR ANALYSIS; HAIR COLLECTION; HAIR FOLLICLE; HAIR GROWTH; HAIR SAMPLE; HAIR STORAGE; HAIR TEXTURE; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MORPHOLOGY; OCCUPATIONAL EXPOSURE; PHYSICAL CHEMISTRY; PRENATAL DRUG EXPOSURE; RADIOIMMUNOASSAY; REVIEW; SAMPLING; SEBACEOUS GLAND; SEX DETERMINATION; SEXUAL CRIME; SWEAT GLAND;

CHEMISTRY TECHNIQUES, ANALYTICAL; HAIR; HUMANS; PHARMACEUTICAL PREPARATIONS; SPECIMEN HANDLING;

EID: 84876705839     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.13.50     Document Type: Review

References (135)

1. Dinis-Oliveira RJ, Carvalho F, Duarte JA et al. Collection of biological samples in forensic toxicology. Toxicol. Mech. Methods 20(7), 363-414 (2010).
2. Kintz P. Bioanalytical procedures for detection of chemical agents in hair in the case of drug-facilitated crimes. Anal. Bioanal. Chem. 388(7), 1467-1474 (2007).
3. Cooper GA, Kronstrand R, Kintz P. Society of Hair Testing guidelines for drug testing in hair. Forensic Sci. Int. 218(1-3), 20-24 (2012).
4. Gallardo E, Queiroz JA. The role of alternative specimens in toxicological analysis. Biomed. Chromatogr. 22(8), 795-821 (2008).
5. Barroso M, Gallardo E, Queiroz JA. Bioanalytical methods for the determination of cocaine and metabolites in human biological samples. Bioanalysis 1(5), 977-1000 (2009).
6. Barroso M, Gallardo E, Vieira DN, Queiroz JA, Lopez-Rivadulla M. Bioanalytical procedures and recent developments in the determination of opiates/opioids in human biological samples. Anal. Bioanal. Chem. 400(6), 1665-1690 (2011).
7. Villain M, Cirimele V, Kintz P. Hair analysis in toxicology. Clin. Chem. Lab. Med. CCLM/FESCC 42(11), 1265-1272 (2004).
8. Kintz P. Value of the concept of minimal detectable dosage in human hair. Forensic Sci. Int. 218(1-3), 28-30 (2012).
9. Barroso M, Dias M, Vieira DN, Lopez-Rivadulla M, Queiroz JA. Simultaneous quantitation of morphine, 6-acetylmorphine, codeine, 6-acetylcodeine and tramadol in hair using mixed-mode solid-phase extraction and gas chromatography-mass spectrometry. Anal. Bioanal. Chem. 396(8), 3059-3069 (2010).
10. Kintz P. Value of hair analysis in postmortem toxicology. Forensic Sci. Int. 142(2-3), 127-134 (2004).
11. Kintz P, Mangin P. Simultaneous determination of opiates, cocaine and major metabolites of cocaine in human hair by gas chromotography/mass spectrometry (GC-MS). Forensic Sci. Int., 73(2) 93-100 1995
12. Bush DM. The U.S. Mandatory Guidelines for Federal Workplace Drug Testing Programs: current status and future considerations. Forensic Sci. Int. 174(2-3), 111-119 (2008).
13. Caplan YH, Goldberger BA. Alternative specimens for workplace drug testing. J. Anal. Toxicol. 25(5), 396-399 (2001).
14. Negrusz A, Gaensslen RE. Analytical developments in toxicological investigation of drug-facilitated sexual assault. Anal. Bioanal. Chem. 376(8), 1192-1197 (2003).
15. Gray T, Huestis M. Bioanalytical procedures for monitoring in utero drug exposure. Anal. Bioanal. Chem. 388(7), 1455-1465 (2007).
16. Lozano J, Garcia-Algar O, Vall O, De La Torre R, Scaravelli G, Pichini S. Biological matrices for the evaluation of in utero exposure to drugs of abuse. Ther. Drug Monit. 29(6), 711-734 (2007).
17. Dumestre-Toulet V, Cirimele V, Ludes B, Gromb S, Kintz P. Hair analysis of seven bodybuilders for anabolic steroids, ephedrine, and clenbuterol. J. Forensic Sci. 47(1), 211-214 (2002).
18. Bresson M, Cirimele V, Villain M, Kintz P. Doping control for metandienone using hair analyzed by gas chromatography-tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 836(1-2), 124-128 (2006).
19. Kintz P, Tracqui A, Mangin P. Pharmacological studies on meprobamate incorporation in human beard hair. Int J. Legal Med. 105(5), 283-287 (1993).
20. Tracqui A, Kreissig P, Kintz P, Pouliquen A, Mangin P. Determination of amitriptyline in the hair of psychiatric patients. Hum. Exp. Toxicol. 11(5), 363-367 (1992).
21. Uematsu T, Sato R, Suzuki K, Yamaguchi S, Nakashima M. Human scalp hair as evidence of individual dosage history of haloperidol: method and retrospective study. Eur. J. Clin. Pharmacol. 37(3), 239-244 (1989).
22. Pragst F, Auwaerter V, Sporkert F, Spiegel K. Analysis of fatty acid ethyl esters in hair as possible markers of chronically elevated alcohol consumption by headspace solid-phase microextraction (HS-SPME) and gas chromatography-ass spectrometry (GC-S). Forensic Sci. Int. 121(1-2), 76-88 (2001).
23. Agius R, Kintz P. Guidelines for European workplace drug and alcohol testing in hair. Drug Test. Anal. 2(8), 367-376 (2010).
24. Headington JT. Transverse microscopic anatomy of the human scalp. A basis for a morphometric approach to disorders of the hair follicle. Arch. Dermatol. 120(4), 449-456 (1984).
25. Montagna W, Van Scott E. The biology of hair growth. In:The Anatomy of the Hair Follicle . Montagna W, Ellis RA (Eds). Academic Press, NY, USA, 39-64 (1958).
26. Nakahara Y, Takahashi K, Kikura R. Hair analysis for drugs of abuse. X. Effect of physicochemical properties of drugs on the incorporation rates into hair. Biol. Pharm. Bull. 18(9), 1223-1227 (1995).
27. Ozeki H, Ito S, Wakamatsu K. Chemical characterization of melanins in sheep wool and human hair. Pigment Cell Res. 9(2), 51-57 (1996).
28. Slawson MH, Wilkins DG, Rollins DE. The incorporation of drugs into hair: relationship of hair color and melanin concentration to phencyclidine incorporation. J. Anal. Toxicol. 22(6), 406-413 (1998).
29. Harkey MR. Anatomy and physiology of hair. Forensic Sci. Int. 63(1-3), 9-18 (1993).
30. Cooper GA. Hair testing is taking root. Ann. Clin. Biochem. 48(Pt 6), 516-530 (2011).
31. Henderson GL. Mechanisms of drug incorporation into hair. Forensic Sci. Int. 63(1-3), 19-29 (1993).
32. Baumgartner WA, Hill VA, Blahd WH. Hair analysis for drugs of abuse. J. Forensic Sci. 34, 1433-1453 (1989).
33. Lee S, Han E, Kim E et al. Simultaneous quantification of opiates and effect of pigmentation on its deposition in hair. Arch. Pharm. Res. 33(11), 1805-1811 (2010).
34. Rollins DE, Wilkins DG, Krueger GG et al. The effect of hair color on the incorporation of codeine into human hair. J. Anal. Toxicol. 27(8), 545-551 (2003).
35. Pragst F, Balikova MA. State of the art in hair analysis for detection of drug and alcohol abuse. Clin. Chim. Acta 370(1-2), 17-49 (2006).
36. De La Torre R, Pichini S. Usefulness of sweat testing for the detection of cannabis smoke. Clin. Chem. 50(11), 1961-1962 (2004).
37. Concheiro M, Shakleya DM, Huestis MA. Simultaneous analysis of buprenorphine, methadone, cocaine, opiates and nicotine metabolites in sweat by liquid chromatography tandem mass spectrometry. Anal. Bioanal. Chem. 400(1), 69-78 (2011).
38. Kintz P. Segmental hair analysis can demonstrate external contamination in postmortem cases. Forensic Sci. Int. 215(1-3), 73-76 (2012).
39. Dinis-Oliveira RJ, Carvalho F, Duarte JA, Proenca JB, Santos A, Magalhaes T. Clinical and forensic signs related to cocaine abuse. Curr. Drug Abuse Rev. 5(1), 64-83 (2012).
40. Dinis-Oliveira RJ, Carvalho F, Moreira R et al. Clinical and forensic signs related to opioids abuse. Curr. Drug Abuse Rev. 5(4), 273-290 (2012).
41. Barroso M, Dias M, Vieira DN, Queiroz JA, Lopez-Rivadulla M. Development and validation of an analytical method for the simultaneous determination of cocaine and its main metabolite, benzoylecgonine, in human hair by gas chromatography/mass spectrometry. Rapid Commun. Mass Spectrom. 22(20), 3320-3326 (2008).
42. Gouveia CA, Oliveira A, Pinho S et al. Simultaneous quantification of morphine and cocaine in hair samples from drug addicts by GC-EI/MS. Biomed. Chromatogr. BMC 26(8), 1041-1047 (2012).
43. Tsanaclis L, Wicks JF. Differentiation between drug use and environmental contamination when testing for drugs in hair. Forensic Sci. Int. 176(1), 19-22 (2008).
44. Joseph RE, Su TP, Cone EJ. In vitro binding studies of drugs to hair: influence of melanin and lipids on cocaine binding to Caucasoid and Africoid hair. J. Analyt. Toxicol. 20(6), 338-344 (1996).
45. Nakahara Y, Takahashi K, Shimamine M, Saitoh A. Hair analysis for drugs of abuse. IV. Determination of total morphine and confirmation of 6-acetylmorphine in monkey and human hair by GC-MS. Arch. Toxicol. 66(9), 669-674 (1992).
46. Kronstrand R, Scott K. Drug incorporation into hair. In:Analytical and Pratical Aspects of Drug Testing in Hair. Kintz P (Ed.). CRC Press, Boca Raton, FL, USA 1-24 (2007).
47. Nakahara Y, Takahashi K, Kikura R. Hair analysis for drug of abuse X. Effect of physicochemical properties of drugs on incorporation rates into hair. Biol. Pharmaceut. Bull. 18(9), 1223-1227 (1995).
48. Lyden A, Larsson B, Lindquist NG. Studies on the melanin affinity of haloperidol. Arch. Int. Pharmacodyn. Ther. 259(2), 230-243 (1982).
49. Cone EJ, Joseph R. Drug testing in hair. In:The Potential for Bias in Hair Testing for Drugs of Abuse . Kintz P (Ed.). CRC Press, FL, USA, 69-93 (1996).
50. Skopp G, Potsch L, Moeller MR. On cosmetically treated hair - aspects and pitfalls of interpretation. Forensic Sci. Int. 84(1-3), 43-52 (1997).
51. Cirimele V, Kintz P, Mangin P. Detection and quantification of lorazepam in human hair by GC-MS/NCI in a case of traffic accident. Int. J. Legal Med. 108(5), 265-267 (1996).
52. Bergfeld WF, Belsito DV, Marks JG Jr, Andersen FA. Safety of ingredients used in cosmetics. J. Am. Acad. Dermatol. 52(1), 125-132 (2005).
53. Kintz P, Cirimele V, Ludes B. Pharmacological criteria that can affect the detection of doping agents in hair. Forensic Sci. Int. 107(1-3), 325-334 (2000).
54. Boumba VA, Ziavrou KS, Vougiouklakis T. Hair as a biological indicator of drug use, drug abuse or chronic exposure to environmental toxicants. Int. J. Toxicol. 25(3), 143-163 (2006).
55. Delauder SF, Kidwell DA. The incorporation of dyes into hair as a model for drug binding. Forensic Sci. Int. 107(1-3), 93-104 (2000).
56. Yegles M, Marson Y, Wennig R. Influence of bleaching on stability of benzodiazepines in hair. Forensic Sci. Int. 107(1-3), 87-92 (2000).
57. Jurado C, Kintz P, Menendez M, Repetto M. Influence of the cosmetic treatment of hair on drug testing. Int. J. Legal Med. 110(3), 159-163 (1997).
58. Sen J. Human hair in personal identification and documenting drug and substance abuse. Anthropologist 12(1), 47-58 (2010).
59. Rothe M, Pragst F, Thor S, Hunger J. Effect of pigmentation on the drug deposition in hair of grey-haired subjects. Forensic Sci. Int. 84(1-3), 53-60 (1997).
60. Vignali C, Stramesi C, Vecchio M, Groppi A. Hair testing and self-report of cocaine use. Forensic Sci. Int. 215(1-3), 77-80 (2012).
61. Kelly RC, Mieczkowski T, Sweeney SA, Bourland JA. Hair analysis for drugs of abuse. Hair color and race differentials or systematic differences in drug preferences? Forensic Sci. Int. 107(1-3), 63-86 (2000).
62. Polettini A, Cone EJ, Gorelick DA, Huestis MA. Incorporation of methamphetamine and amphetamine in human hair following controlled oral methamphetamine administration. Anal. Chim Acta 726, 35-43 (2012).
63. Nakahara Y, Kikura R, Takahashi K. Hair analysis for drugs of abuse. VIII. Effective extraction and determination of 6-acetylmorphine and morphine in hair with trifluoroacetic acid-methanol for the confirmation of retrospective heroin use by gas chromatography-mass spectrometry. J. Chromatogr. B Biomed. Appl. 657(1), 93-101 (1994).
64. Wennig R. Potential problems with the interpretation of hair analysis results. Forensic Sci. Int. 107(1-3), 5-12 (2000).
65. Jurado C, Sachs H. Proficiency test for the analysis of hair for drugs of abuse, organized by the Society of Hair Testing. Forensic Sci. Int. 133(1-2), 175-178 (2003).
66. Musshoff F, Madea B. Analytical pitfalls in hair testing. Anal. Bioanal. Chem. 388(7), 1475-1494 (2007).
67. Society of Hair Testing. Recommendations for hair testing in forensic cases. Forensic Sci. Int. 145(2-3), 83-84 (2004).
68. Nakahara Y. Hair analysis for abused and therapeutic drugs. J. Chromatogr. B Biomed. Sci. Appl. 733(1-2), 161-180 (1999).
69. Tagliaro F, Smith FP, De Battisti Z, Manetto G, Marigo M. Hair analysis, a novel tool in forensic and biomedical sciences: new chromatographic and electrophoretic/electrokinetic analytical strategies. J. Chromatogr. B Biomed. Sci. Appl. 689(1), 261-271 (1997).
70. Kintz P. Analytical and Practical Aspects of Drug Testing in Hair. CRC Press, Taylor and Francis Group, Boca Raton, FL, USA (2007).
71. Pragst F, Sachs H, Kintz P. Hair analysis for cocaine continues to be a valuable tool in forensic and clinical toxicology. J. Anal. Toxicol. 34(6), 354-355; author reply 355-356 (2010).
72. Baptista MJ, Monsanto PV, Pinho Marques EG et al. Hair analysis for delta(9)-THC, delta(9)-THC-COOH, CBN and CBD, by GC-MS-EI. Comparison with GC-MS-NCI for delta(9)-THC-COOH. Forensic Sci. Int. 128(1-2), 66-78 (2002).
73. Favretto D, Vogliardi S, Stocchero G, Nalesso A, Tucci M, Ferrara SD. High performance liquid chromatography-high resolution mass spectrometry and micropulverized extraction for the quantification of amphetamines, cocaine, opioids, benzodiazepines, antidepressants and hallucinogens in 2.5 mg hair samples. J. Chromatogr. A 1218(38), 6583-6595 (2011).
74. Kauert G, Rohrich J. Concentrations of delta 9-tetrahydrocannabinol, cocaine and 6-monoacetylmorphine in hair of drug abusers. Int J. Legal Med. 108(6), 294-299 (1996).
75. Kronstrand R, Nystrom I, Strandberg J, Druid H. Screening for drugs of abuse in hair with ion spray LC-MS-MS. Forensic Sci. Int. 145(2-3), 183-190 (2004).
76. Moller M, Aleksa K, Walasek P, Karaskov T, Koren G. Solid-phase microextraction for the detection of codeine, morphine and 6-monoacetylmorphine in human hair by gas chromatography-mass spectrometry. Forensic Sci. Int. 196(1-3), 64-69 (2010).
77. Scheidweiler KB, Huestis MA. Simultaneous quantification of opiates, cocaine, and metabolites in hair by LC-APCI-MS/MS. Anal. Chem. 76(15), 4358-4363 (2004).
78. De Toledo FC, Yonamine M, De Moraes Moreau RL, Silva OA. Determination of cocaine, benzoylecgonine and cocaethylene in human hair by solid-phase microextraction and gas chromatography-mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 798(2), 361-365 (2003).
79. Uhl M. Tandem mass spectrometry. a helpful tool in hair analysis for the forensic expert. Forensic Sci. Int. 107(1-3), 169-179 (2000).
80. Kintz P. Drug Testing in Hair. CRC Press, FL, USA (1996).
81. Sachs H, Kintz P. Testing for drugs in hair: critical review of chromatographic procedures since 1992. J. Chromatogr. B Biomed. Sci. Appl.713(1), 147-161 (1998).
82. Romolo FS, Rotolo MC, Palmi I, Pacifici R, Lopez A. Optimized conditions for simultaneous determination of opiates, cocaine and benzoylecgonine in hair samples by GC-MS. Forensic Sci. Int. 138(1-3), 17-26 (2003).
83. Cognard E, Rudaz S, Bouchonnet S, Staub C. Analysis of cocaine and three of its metabolites in hair by gas chromatography-mass spectrometry using ion-trap detection for CI/MS/MS. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 826(1-2), 17-25 (2005).
84. Guthery B, Bassindale T, Bassindale A, Pillinger CT, Morgan GH. Qualitative drug analysis of hair extracts by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry. J Chromatogr A 1217(26), 4402-4410 (2010).
85. Baumgartner AM, Jones PF, Baumgartner WA, Black CT. Radioimmunoassay of hair for determining opiate-abuse histories. J. Nucl. Med. 20(7), 748-752 (1979).
86. Hadidi KA, Almasad JK, Al-Nsour T, Abu-Ragheib S. Determination of tramadol in hair using solid phase extraction and GC-MS. Forensic Sci. Int. 135(2), 129-136 (2003).
87. Gottardo R, Bortolotti F, De Paoli G, Pascali JP, Miksik I, Tagliaro F. Hair analysis for illicit drugs by using capillary zone electrophoresis- electrospray ionization-ion trap mass spectrometry. J. Chromatogr. A 1159(1-2), 185-189 (2007).
88. Gronholm M, Lillsunde P. A comparison between on-site immunoassay drug-testing devices and laboratory results. Forensic Sci. Int. 121(1-2), 37-46 (2001).
89. Verstraete AG. Oral fluid testing for driving under the influence of drugs: history, recent progress and remaining challenges. Forensic Sci. Int. 150(2-3), 143-150 (2005).
90. Barroso M, Dias M, Vieira DN, Lopez-Rivadulla M, Queiroz JA. Mixed-mode solid-phase extraction for sample cleanup in hair analysis for methadone and its main metabolite. Biomedical Chromatography 24(11), 1240-1246 (2010).
91. Cordero R, Paterson S. Simultaneous quantification of opiates, amphetamines, cocaine and metabolites and diazepam and metabolite in a single hair sample using GC-MS. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 850(1-2), 423-431 (2007).
92. Fernandez P, Lago M, Lorenzo RA, Carro AM, Bermejo AM, Tabernero MJ. Optimization of a rapid microwave-assisted extraction method for the simultaneous determination of opiates, cocaine and their metabolites in human hair. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 877(18-19), 1743-1750 (2009).
93. Paterson S, Cordero R, Stearns E. Chronic drug use confirmed by hair analysis: its role in understanding both the medical cause of death and the circumstances surrounding the death. J. Forensic Legal Med. 16(3), 143-147 (2009).
94. Morrison JF, Chesler SN, Yoo WJ, Selavka CM. Matrix and modifier effects in the supercritical fluid extraction of cocaine and benzoylecgonine from human hair. Anal. Chem. 70(1), 163-172 (1998).
95. Niessen WMA. Principles and instrumentation of gas chromatography-mass spectrometry. In:Current Practice of Gas Chromatography-Mass Spectrometry. Niessen WMA (Ed.). Marcel Dekker, Inc., NY, USA, 1-29 (2001).
96. Girod C, Staub C. Analysis of drugs of abuse in hair by automated solid-phase extraction, GC-EI-MS and GC ion trap-CI-MS. Forensic Sci. Int. 107(1-3), 261-271 (2000).
97. Barroso M, Costa S, Dias M, Vieira DN, Queiroz JA, Lopez-Rivadulla M. Analysis of phenylpiperazine-like stimulants in human hair as trimethylsilyl derivatives by gas chromatography-mass spectrometry. J. Chromatogr. A 1217(40), 6274-6280 (2010).
98. Montagna M, Stramesi C, Vignali C, Groppi A, Polettini A. Simultaneous hair testing for opiates, cocaine, and metabolites by GC-MS: a survey of applicants for driving licenses with a history of drug use. Forensic Sci. Int. 107(1-3), 157-167 (2000).
99. Nielsen MK, Johansen SS, Dalsgaard PW, Linnet K. Simultaneous screening and quantification of 52 common pharmaceuticals and drugs of abuse in hair using UPLC-TOF-MS. Forensic Sci. Int. 196(1-3), 85-92 (2010).
100. Musshoff F, Madea B. New trends in hair analysis and scientific demands on validation and technical notes. Forensic Sci. Int. 165(2-3), 204-215 (2007).
101. Moreira PN, De Pinho PG, Baltazar MT, Bastos ML, Carvalho F, Dinis-Oliveira RJ. Quantification of paraquat in postmortem samples by gas chromatography-ion trap mass spectrometry and review of the literature. Biomed. Chromatogr. 26(3), 338-349 (2012).
102. European Medicines Agency. Guidelines on Bioanalytical Method Validation. London, UK (2011).
103. Kintz P. Gas chromatographic analysis of nicotine and cotinine in hair. J. Chromatogr. 580(1-2), 347-353 (1992).
104. Sachs H, Denk R, Raff I. Determination of dihydrocodeine in hair of opiate addicts by GC-MS. Int J. Legal Med. 105(5), 247-250 (1993).
105. Nakahara Y, Kikura R, Yasuhara M, Mukai T. Hair analysis for drug abuse. XIV. Identification of substances causing acute poisoning using hair root. I. Methamphetamine. Forensic Sci. Int. 84(1-3), 157-164 (1997).
106. Takayama N, Tanaka S, Hayakawa K. Determination of stimulants in a single human hair sample by high-performance liquid chromatographic method with chemiluminescence detection. Biomed. Chromatogr. 11(1), 25-28 (1997).
107. Nakahara Y, Kikura R. Hair analysis for drugs of abuse. XVIII. 3,4-Methylenedioxymethamphetamine (MDMA) disposition in hair roots and use in identification of acute MDMA poisoning. Biol. Pharm. Bull. 20(9), 969-972 (1997).
108. Graham K, Koren G, Klein J, Schneiderman J, Greenwald M. Determination of gestational cocaine exposure by hair analysis. JAMA 262(23), 3328-3330 (1989).
109. Klein J, Chitayat D, Koren G. Hair analysis as a marker for fetal exposure to maternal smoking. N. Engl. J. Med. 328(1), 66-67 (1993).
110. Kintz P, Kieffer I, Messer J, Mangin P. Nicotine analysis in neonates hair for measuring gestational exposure to tobacco. J. Forensic Sci. 38(1), 119-123 (1993).
111. Dinis-Oliveira RJ, Magalhaes T. Children intoxications: what is abuse and what is not abuse. Trauma Violence Abuse 14, 113-132 (2013).
112. Gaillard Y, Vayssette F, Balland A, Pepin G. Gas chromatographic-tandem mass spectrometric determination of anabolic steroids and their esters in hair. Application in doping control and meat quality control. J. Chromatogr. B Biomed. Sci. Appl. 735(2), 189-205 (1999).
113. Thieme D, Grosse J, Sachs H, Mueller RK. Analytical strategy for detecting doping agents in hair. Forensic Sci. Int. 107(1-3), 335-345 (2000).
114. Kintz P, Cirimele V, Ludes B. Discrimination of the nature of doping with 19-norsteroids through hair analysis. Clinical Chem. 46(12), 2020-2022 (2000).
115. Cirimele V, Tracqui A, Kintz P, Ludes B. First identification of prednisone in human hair by liquid chromatography-ionspray mass spectrometry. J. Anal. Toxicol. 23(3), 225-226 (1999).
116. Gleixner A, Sauerwein H, Meyer HH. Detection of the anabolic beta 2-adrenoceptor agonist clenbuterol in human scalp hair by HPLC/EIA. Clin. Chem. 42(11), 1869-1871 (1996).
117. Kintz P. Consensus of the Society of Hair Testing on hair testing for chronic excessive alcohol consumption 2011. Forensic Sci. Int. 218(1-3), 2 (2012).
118. Hall JA, Moore CB. Drug facilitated sexual assault - a review. J. Forensic Leg. Med. 15(5), 291-297 (2008).
119. Payne-James J, Rogers D. Drug-facilitated sexual assault, ladettes and alcohol. J. R. Soc. Med. 95(7), 326-327 (2002).
120. Bechtel LK, Holstege CP. Criminal poisoning: drug-facilitated sexual assault. Emerg. Med. Clin. North Am. 25(2), 499-525; abstract x (2007).
121. Kintz P, Villain M, Dumestre-Toulet V, Ludes B. Drug-facilitated sexual assault and analytical toxicology: the role of LC-MS/MS A case involving zolpidem. J. Clin. Forensic Med. 12(1), 36-41 (2005).
122. Mcgregor MJ, Ericksen J, Ronald LA, Janssen PA, Van Vliet A, Schulzer M. Rising incidence of hospital-reported drug-facilitated sexual assault in a large urban community in Canada. Retrospective population-based study. Canadian J. Public Health 95(6), 441-445 (2004).
123. Lebeau MA. Guidance for improved detection of drugs used to facilitate crimes. Ther. Drug Monit. 30(2), 229-233 (2008).
124. Harper NS. Drug-facilitated sexual assault. In. Child Abuse and Neglect: Diagnosis, Treatment and Evidence. Jenny C (Ed.). Elsevier Inc., MI, USA, 118-126 (2011).
125. Oral R, Bayman L, Assad A et al. Illicit drug exposure in patients evaluated for alleged child abuse and neglect. Pediatr. Emerg. Care 27(6), 490-495 (2011).
126. Kintz P, Cirimele V, Jamey C, Ludes B. Testing for GHB in hair by GC-MS/MS after a single exposure. Application to document sexual assault. J. Forensic Sci. 48(1), 195-200 (2003).
127. Frison G, Favretto D, Tedeschi L, Ferrara SD. Detection of thiopental and pentobarbital in head and pubic hair in a case of drug-facilitated sexual assault. Forensic Sci. Int. 133(1-2), 171-174 (2003).
128. Kronstrand R, Nystrom I, Forsman M, Kall K. Hair analysis for drugs in drivers license regranting. A Swedish pilot study. Forensic Sci. Int. 196(1-3), 55-58 (2010).
129. Polla M, Stramesi C, Pichini S, Palmi I, Vignali C, Dallolio G. Hair testing is superior to urine to disclose cocaine consumption in drivers licence regranting. Forensic Sci. Int. 189(1-3), e41-e43 (2009).
130. Jones GR. Interpretation of postmortem drug levels. In:Postmortem Toxicology of Abused Drugs . Karch SB (Ed.). CRC Press, Boca Raton, FL, USA, 115-120 (2008).
131. Kintz P, Ginet M, Cirimele V. Multi-element screening by ICP-MS of two specimens of Napoleons hair. J. Anal. Toxicol. 30(8), 621-623 (2006).
132. Kintz P, Ginet M, Marques N, Cirimele V. Arsenic speciation of two specimens of Napoleons hair. Forensic Sci. Int. 170(2-3), 204-206 (2007).
133. Smith H. The interpretation of the arsenic content of human hair. J. Forensic Sci. Soc. 240, 192-199 (1964).
134. Smith RA. A method to distinguish between arsenic in and on human hair. Environ. Res. 12(2), 171-173 (1976).
135. Madry MM, Rust KY, Guglielmello R, Baumgartner MR, Kraemer T. Metabolite to parent drug concentration ratios in hair for the differentiation of tramadol intake from external contamination and passive exposure. Forensic Sci. Int. 223(1-3), 330-334 (2012).