Quantification of paraquat in postmortem samples by gas chromatography-ion trap mass spectrometry and review of the literature

Biomedical Chromatography

Volumn 26, Issue 3, 2012, Pages 338-349

  Moreira, Pedro Nuno ^a   de Pinho, Paula Guedes ^b   Baltazar, Maria Teresa ^b,c,d   Bastos, Maria Lourdes ^b   Carvalho, Félix ^b   Dinis Oliveira, Ricardo Jorge ^b,c,d,e  

^a IP   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c Inst Politec de Saude Do N Coop de Ensino Superior Politecnico e Universitario: IPSN CESPU   (Portugal)

^d UNIVERSITY INSTITUTE OF HEALTH SCIENCES IUCS   (Portugal)

^e University of Porto   (Portugal)

Author keywords

Forensic samples; GC IT MS; Paraquat; Postmortem

Indexed keywords

BLOOD; FORENSIC SCIENCE; GAS CHROMATOGRAPHY; ION CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION; REGRESSION ANALYSIS; WEED CONTROL;

ANALYTICAL METHOD; CLINICAL OUTCOME; FORENSIC SAMPLES; GAS CHROMATOGRAPHY-ION TRAP MASS SPECTROMETRIES; PARAQUAT; PLASMA SAMPLES; POST-MORTEM SAMPLES; POSTMORTEM; URINE SAMPLE; WHOLE BLOOD;

HERBICIDES;

PARAQUAT;

ARTICLE; AUTOPSY; BIOACCUMULATION; BLOOD SAMPLING; CHEMICAL STRUCTURE; FORENSIC TOXICOLOGY; GAS CHROMATOGRAPHY ION TRAP MASS SPECTROMETRY; HUMAN; ION TRAP MASS SPECTROMETRY; KIDNEY EXAMINATION; LUNG EXAMINATION; MASS FRAGMENTOGRAPHY; OUTCOME ASSESSMENT; PARAQUAT POISONING; PREDICTION; SOLID PHASE EXTRACTION; URINALYSIS;

EID: 84856574478     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1663     Document Type: Article

References (68)

1. Akerblom M. Rapid determination of paraquat in urine with ion-pair extraction and spectrophotometry. Bulletin of Environmental Contamination and Toxicology 1990; 45: 157-164.
2. Ariffin MM and Anderson RA. LC/MS/MS analysis of quaternary ammonium drugs and herbicides in whole blood. Journal of Chromatography. B: Analytical Technologies in the Biomedical and Life Sciences 2006; 842: 91-97.
3. Arys K, Van Bocxlaer J, Clauwaert K, Lambert W, Piette M, Van Peteghem C and De Leenheer A. Quantitative determination of paraquat in a fatal intoxication by HPLC-DAD following chemical reduction with sodium borohydride. Journal of Analytical Toxicology 2000; 24: 116-121.
4. Bismuth C, Baud FJ, Garnier R, Muszinski J and Houze P. Paraquat poisoning: biological presentation. Journal de Toxicologie Clinique et Expérimentale 1988; 8: 211-218.
5. Bowles MR, Eyles DW, Hampson EC and Pond, S.M. Quantitation of paraquat in biological samples by radioimmunoassay using a monoclonal antibody. Fundamental and Applied Toxicology: Official Journal of the Society of Toxicology 1992; 19: 375-379.
6. Brunetto MR, Morales AR, Gallignani M, Burguera JL and Burguera M. Determination of paraquat in human blood plasma using reversed-phase ion-pair high-performance liquid chromatography with direct sample injection. Talanta 2003, 59: 913-921.
7. Carneiro MC. Comparison of capillary electrophoresis and reversed-phase ion-pair high-performance liquid chromatography for the determination of paraquat, diquat and difenzoquat. Journal of Chromatography A 1994; 669: 217-244.
8. Castro R, Moyano E and Galceran MT. Ion-pair liquid chromatography-atmospheric pressure ionization mass spectrometry for the determination of quaternary ammonium herbicides. Journal of Chromatography A 1999; 830: 145-154.
9. Castro R, Moyano E and Galceran MT. On-line ion-pair solid-phase extraction-liquid chromatography-mass spectrometry for the analysis of quaternary ammonium herbicides. Journal of Chromatography A 2000; 869: 441-449.
10. Castro R, Moyano E and Galceran MT. Determination of quaternary ammonium pesticides by liquid chromatography-electrospray tandem mass spectrometry. Journal of Chromatography A 2001; 914: 111-121.
11. Castro R, Prata C, Oliveira L, Carvalho MJ, Santos J, Carvalho F and Morgado T. [Paraquat intoxication and hemocarboperfusion]. Acta Médica Portuguesa 2005; 18: 423-431.
12. Coxon RE, Rae C, Gallacher G and Landon, J. Development of a simple, fluoroimmunoassay for paraquat. Clinica Chimica Acta: International Journal of Clinical Chemistry 1988; 175: 297-305.
13. de Almeida RM and Yonamine M. Gas chromatographic-mass spectrometric method for the determination of the herbicides paraquat and diquat in plasma and urine samples. Journal of Chromatography. B: Analytical Technologies in the Biomedical and Life Sciences 2007; 853: 260-264.
14. Dinis-Oliveira RJ, De Jesus Valle MJ, Bastos ML, Carvalho F and Sanchez Navarro A. Kinetics of paraquat in the isolated rat lung: Influence of sodium depletion. Xenobiotica 2006a; 36: 724-737.
15. Dinis-Oliveira RJ, Remiao F, Carmo H, Duarte JA, Navarro AS, Bastos ML and Carvalho F. Paraquat exposure as an etiological factor of Parkinson's disease. Neurotoxicology 2006b; 27: 1110-1122.
16. Dinis-Oliveira RJ, Remiao F, Duarte JA, Ferreira R, Sanchez Navarro A, Bastos ML and Carvalho F. P-glycoprotein induction: an antidotal pathway for paraquat-induced lung toxicity. Free Radical Biology and Medicine 2006c; 41: 1213-1224.
17. Dinis-Oliveira RJ, Duarte JA, Sanchez-Navarro A, Remiao F, Bastos ML and Carvalho F. Paraquat poisonings: mechanisms of lung toxicity, clinical features, and treatment. Critical Reviews in Toxicology 2008; 38: 13-71.
18. Dinis-Oliveira RJ, de Pinho PG, Santos L, Teixeira H, Magalhaes T, Santos A, de Lourdes Bastos M, Remiao F, Duarte JA and Carvalho F. Postmortem analyses unveil the poor efficacy of decontamination, anti-inflammatory and immunosuppressive therapies in paraquat human intoxications. PLoS ONE 2009; 4: e7149.
19. Dinis-Oliveira RJ, Carvalho F, Duarte JA, Remiao F, Marques A, Santos A and Magalhaes T. Collection of biological samples in forensic toxicology. Toxicology Mechanisms and Methods 2010; 20: 363-414.
20. Draffan GH, Clare RA, Davies DL, Hawksworth G, Murray S and Davies DS. Quantitative determination of the herbicide paraquat in human plasma by gas chromatographic and mass spectrometric methods. Journal of Chromatography 1977; 139: 311-320.
21. EMEA. E.M.A., Note for Guidance on Validation of Analytical Procedures. Text and Methodology. EMEA: London, 1995.
22. Fatori D and Hunter WM. Radioimmunoassay for serum paraquat. Clinica Chimica Acta 1980; 100: 81-90.
23. Fell AF, Jarvie DR and Stewart MJ. Analysis for paraquat by second- and fourth-derivative spectroscopy. Clinical Chemistry 1981; 27: 286-292.
24. Fuke C, Ameno K, Ameno S, Kiriu T, Shinohara T, Sogo K and Ijiri I. A rapid, simultaneous determination of paraquat and diquat in serum and urine using second-derivative spectroscopy. Journal of Analytical Toxicology 1992; 16: 214-216.
25. Fuke C, Arao T, Morinaga Y, Takaesu H, Ameno K and Miyazaki T. Analysis of paraquat, diquat and two diquat metabolites in biological materials by high-performance liquid chromatography. Legal Medicine (Tokyo, Japan) 2002; 4: 156-163.
26. Gill R, Qua SC and Moffat, A. C. High-performance liquid chromatography of paraquat and diquat in urine with rapid sample preparation involving ion-pair extraction on disposable cartridges of octadecyl-silica. Journal of Chromatography 1983; 255: 483-490.
27. Grey L, Nguyen B and Yang P. Liquid chromatography-electrospray ionization isotope dilution mass spectrometry analysis of paraquat and diquat using conventional and multilayer solid-phase extraction cartridges. Journal of Chromatography A 2002; 958: 25-33.
28. Gronewold A, Dettling A, Haffner HT and Skopp G. Doxepin and nordoxepin concentrations in body fluids and tissues in doxepin associated deaths. Forensic Science International 2009; 190: 74-79.
29. Hara S, Sasaki N, Takase D, Shiotsuka S, Ogata K, Futagami K and Tamura K. Rapid and sensitive HPLC method for the simultaneous determination of paraquat and diquat in human serum. Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry 2007; 23: 523-526.
30. Houze P, Baud FJ, Mouy R, Bismuth C, Bourdon R and Scherrmann JM. Toxicokinetics of paraquat in humans. Human and Experimental Toxicology 1990; 9: 5-12.
31. Ito S, Nagata T, Kudo K, Kimura K and Imamura T. Simultaneous determination of paraquat and diquat in human tissues by high-performance liquid chromatography. Journal of Chromatography 1993; 617: 119-123.
32. Jarvie DR and Stewart MJ. The rapid extraction of paraquat from plasma using an ion-pairing technique. Clinica Chimica Acta; International Journal of Clinical Chemistry 1979; 94: 241-251.
33. Jarvie DR, Fell AF and Stewart MJ. A rapid method for the emergency analysis of paraquat in plasma using a second derivative spectroscopy. Clinica Chimica Acta; International Journal of Clinical Chemistry 1981; 117: 153-165.
34. Kawase S, Kanno S and Skai S. Determination of the herbicides paraquat and diquat in blood and urine by gas chromatography. Journal of Chromatography 1984; 283: 231-240.
35. Kesari R, Rai M and Gupta VK. Spectrophotometric method for determination of paraquat in food and biological samples. Journal of AOAC International 1997; 80: 388-391.
36. Koivunen ME, Gee SJ, Park EK, Lee K, Schenker MB and Hammock BD. Application of an enzyme-linked immunosorbent assay for the analysis of paraquat in human-exposure samples. Archives of Environmental Contamination and Toxicology 2005; 48: 184-190.
37. Kuo TL. Determination of serum paraquat by XAD-2 resin. Clinica Chimica Acta; International Journal of Clinical Chemistry 1984; 144: 273-276.
38. Kuo TL. Determination of paraquat in tissue using ion-pair chromatography in conjunction with spectrophotometry. Forensic Science International 1987; 33: 177-185.
39. Kuo TL. Determination of paraquat in biologic materials by a simplified solid phase extraction and spectrophotometry. Journal of the Formasan Medical Association, Taiwan yi zhi 1995; 94: 243-247.
40. Lee HS, Kim K, Kim JH, Do KS and Lee SK. On-line sample preparation of paraquat in human serum samples using high-performance liquid chromatography with column switching. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1998; 716: 371-374.
41. Lee XP, Kumazawa T, Fujishiro M, Hasegawa C, Arinobu T, Seno H, Ishii A and Sato K. Determination of paraquat and diquat in human body fluids by high-performance liquid chromatography/tandem mass spectrometry. Journal of Mass Spectrometry 2004; 39: 1147-1152.
42. Levitt T. Radioimmunoassay for paraquat. Lancet 1977; 2: 358.
43. Luckenbill K, Thompson J, Middleton O, Kloss J and Apple F. Fentanyl postmortem redistribution: preliminary findings regarding the relationship among femoral blood and liver and heart tissue concentrations. Journal of Analytical Toxicology 2008; 32: 639-643.
44. Ludwig-Kohn H, Sziedat A, Matthaei D and Henning, H.V. Analysis of neutral steroid sulfates by glass capillary gas chromatography-mass spectrometry (GC-MS) from blood of a patient with paraquat poisoning. Clinica Chimica Acta; International Journal of Clinical Chemistry 1982; 121: 189-198.
45. Mallet CR, Lu Z and Mazzeo, J.R. A study of ion suppression effects in electrospray ionization from mobile phase additives and solid-phase extracts. Rapid Communication in Mass Spectrometry 2004; 18: 49-58.
46. Nakagiri I, Suzuki K, Shiaku Y, Kuroda Y, Takasu N and Kohama, A. Rapid quantification of paraquat and diquat in serum and urine using high-performance liquid chromatography with automated sample pretreatment. Journal of Chromatography 1989; 481: 434-438.
47. Nunez O, Moyano E, Puignou L and Galceran MT. Sample stacking with matrix removal for the determination of paraquat, diquat and difenzoquat in water by capillary electrophoresis. Journal of Chromatography A 2001; 912: 353-361.
48. Nunez O, Kim JB, Moyano E, Galceran MT and Terabe, S. Analysis of the herbicides paraquat, diquat and difenzoquat in drinking water by micellar electrokinetic chromatography using sweeping and cation selective exhaustive injection. Journal of Chromatography A 2002a; 961: 65-75.
49. Nunez O, Moyano E and Galceran MT. Capillary electrophoresis-mass spectrometry for the analysis of quaternary ammonium herbicides. Journal of Chromatography A 2002b; 974: 243-255.
50. Nunez O, Moyano E and Galceran MT. Solid-phase extraction and sample stacking-capillary electrophoresis for the determination of quaternary ammonium herbicides in drinking water. Journal of Chromatography A 2002c; 946: 275-282.
51. Nunez O, Moyano E and Galceran MT. High mass accuracy in-source collision-induced dissociation tandem mass spectrometry and multi-step mass spectrometry as complementary tools for fragmentation studies of quaternary ammonium herbicides. Journal of Mass Spectrometry 2004; 39: 873-883.
52. O'Haver TC. Potential clinical applications of derivative and wavelength-modulation spectrometry. Clinical Chemistry 1979; 25: 1548-1553.
53. Paschal DC, Needham LL, Rollen ZJ and Liddle JA. Determination of paraquat in sunflower seeds by reversed-phase high-performance liquid chromatography. Journal of Chromatography 1979; 177: 85-90.
54. Posecion NC, Ostrea, EM and Bielawski DM. Quantitative determination of paraquat in meconium by sodium borohydride-nickel chloride chemical reduction and gas chromatography/mass spectrometry (GC/MS). Journal of Chromatography. B: Analytical Technologies in the Biomedical and Life Sciences 2008; 862: 93-99.
55. Poster DL, Schantz MM, Sander LC and Wise SA. Analysis of polycyclic aromatic hydrocarbons (PAHs) in environmental samples: a critical review of gas chromatographic (GC) methods. Analytical and Bioanalytical Chemistry 2006; 386: 859-881.
56. Quirino JP and Terabe S. Sample stacking of cationic and anionic analytes in capillary electrophoresis. Journal of Chromatography A 2000; 902: 119-135.
57. Rial-Otero R, Cancho-Grande B, Perez-Lamela C, Simal-Gandara J and Arias-Estevez, M. Simultaneous determination of the herbicides diquat and paraquat in water. Journal of Chromatographic Science 2006; 44: 539-542.
58. Shihabi ZK. Stacking in capillary zone electrophoresis. Journal of Chromatography A 2000; 902: 107-117.
59. Shivhare P and Gupta VK. Spectrophotometric method for the determination of paraquat in water, grain and plant materials. The Analyst 1991; 116: 391-393.
60. Taguchi VY, Jenkins SW, Crozier PW and Wang DT. Determination of diquat and paraquat in water by liquid chromatography-(electrospray ionization) mass spectrometry. Journal of the American Society for Mass Spectrometry 1998; 9: 830-839.
61. Van Emon J, Hammock B and Seiber JN. Enzyme-linked immunosorbent assay for paraquat and its application to exposure analysis. Analytical Chemistry 1986; 58: 1866-1873.
62. Van Emon J, Seiber J and Hammock B. Application of an enzyme-linked immunosorbent assay (ELISA) to determine paraquat residues in milk, beef, and potatoes. Bulletin of Environmental Contamination and Toxicology 1987; 39: 490-497.
63. Vidal JL, Vega AB, Lopez FJ and Frenich AG. Application of internal quality control to the analysis of quaternary ammonium compounds in surface and groundwater from Andalusia (Spain) by liquid chromatography with mass spectrometry. Journal of Chromatography A 2004; 1050: 179-184.
64. Vinner E, Stievenart M, Humbert L, Mathieu D and Lhermitte M. Separation and quantification of paraquat and diquat in serum and urine by capillary electrophoresis. Biomedical Chromatography 2001; 15: 342-347.
65. Whitehead RD Jr., Montesano MA, Jayatilaka NK, Buckley B, Winnik B, Needham LL and Barr DB. Method for measurement of the quaternary amine compounds paraquat and diquat in human urine using high-performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 2010; 878: 2548-2553.
66. Winnik B, Barr DB, Thiruchelvam M, Montesano MA, Richfield EK and Buckley B. Quantification of Paraquat, MPTP, and MPP+in brain tissue using microwave-assisted solvent extraction (MASE) and high-performance liquid chromatography-mass spectrometry. Analytical and Bioanalytical Chemistry 2009; 395: 195-201.
67. Woollen BH and Mahler, J.D. An improved spot-test for the detection of paraquat and diquat in biological samples. Clinica Chimica Acta; International Journal of Clinical Chemistry 1987; 167: 225-229.
68. Yuen SH, Bagness JE and Myles D. Spectrophotometric determination of diquat and paraquat in aqueous herbicide formulations. The Analyst 1967; 92: 375-381.