Hair testing is taking root

Annals of Clinical Biochemistry

Volumn 48, Issue 6, 2011, Pages 516-530

  Cooper, Gail Audrey Ann ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE; DIAMORPHINE; MORPHINE 6 ACETATE;

ACCURACY; ALCOHOL CONSUMPTION; ANATOMY; CELL DIVISION; CELL GROWTH; CONTAMINATION; CRIME; CUSTODY; DRUG BLOOD LEVEL; DRUG EXPOSURE; DRUG FATALITY; DRUG SCREENING; DRUG STABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACTION; GOOD LABORATORY PRACTICE; HAIR; HAIR ANALYSIS; HAIR FOLLICLE; HAIR GROWTH; HAIR PIGMENTATION; HAIR TESTING; HEALTH CARE QUALITY; HUMAN; HYGIENE; LABORATORY DIAGNOSIS; LABORATORY TEST; METABOLISM; PHYSIOLOGY; PIGMENTATION; PRACTICE GUIDELINE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RELIABILITY; REVIEW; SEBUM; SWEAT; VASCULARIZATION;

CAUSE OF DEATH; DRUG STABILITY; HAIR; HUMANS; MASS SPECTROMETRY; SENSITIVITY AND SPECIFICITY; SEX OFFENSES; SOLID PHASE EXTRACTION; SPECIMEN HANDLING; STREET DRUGS; SUBSTANCE ABUSE DETECTION; SUBSTANCE-RELATED DISORDERS;

EID: 84856022275     PISSN: 00045632     EISSN: 17581001     Source Type: Journal    
DOI: 10.1258/acb.2011.011112     Document Type: Review

References (168)

1. Society of Hair Testing official website. See www.SOHT.org (last checked 27 February 2011)
2. Society of Hair Testing. Statement of the society of hair testing concerning the examination of drugs in human hair. Forensic Sci Int 1997;84:3-6
3. Society of Hair Testing. Consensus of the Society of Hair Testing on Hair Testing for Doping Agents. See www.SOHT.org/html/Statements.html (last checked 27 February 2011)
4. Society of Hair Testing. Recommendations for hair testing in forensic cases. Forensic Sci Int 2004;145:83-4
5. Kintz P. Consensus of the Society of Hair Testing on hair testing for chronic excessive alcohol consumption. Forensic Sci Int 2010;196:2
6. Harkey MR. Anatomy and physiology of hair. Forensic Sci Int 1993;63:9-18
7. Forslind B. The growing anagen hair. In: Orfanos CE, Happle R, eds. Hair and Hair Diseases. Berlin, Heidelberg, London, Paris, Tokyo, Hong Kong: Springer, 1990: 73-98
8. Montagna W, Van Scott EJ. The anatomy of the hair follicle. In: Montagna W, Ellis RA, eds. The Biology of Hair Growth. New York: Academic Press, 1958: 39-64
9. Randall VA, Ebling FJ. Seasonal changes in human hair growth. Br J Dermatol 1991;124:146-51
10. Potsch L. A discourse on human hair fibres and reflections on the conservation of drug molecules. Int J Leg Med 1996;108:285-93
11. Pragst F, Rothe M, Spiegel K, Sporkert F. Illegal and therapeutic drug concentrations in hair segments - a timetable of drug exposure? Forensic Sci Rev 1998;10:81-112
12. Hartwig S, Auwärter V, Pragst F. Fatty acid ethyl esters in scalp, pubic, axillary, beard and body hair as marker for alcohol misuse. Alcohol Alcohol 2003;38:163-7
13. Myers RJ, Hamilton JB. Regeneration and rate of growth of hair in man. Ann NY Acad Sci 1951;53:562-8
14. Ryder ML. Nutritional factors influencing hair and wool growth. In: Montagna W, Ellis RA, eds. The Biology of Hair Growth. New York: Academic Press, 1958:305-34
15. Chittleborough G, Steel BJ. Is human hair a dosimeter for endogenous zinc and other trace elements? Sci Total Environ 1980;15:25-35
16. Kronstrand R, Scott K. Drug incorporation into hair. In: Kintz P, ed. Analytical and Practical Aspects of Drug Testing in Hair. Boca Raton: CRC Press, 2007: 1-23
17. Baumgartner WA, Hill VA, Bland WH. Hair analysis for drugs of abuse. J Forensic Sci 1993;34:1433-53
18. Harkey MR. Technical issues concerning hair analysis for drugs of abuse. NIDA Res Monogr 1995;154:218-34
19. Huestis MA, Oyler JM, Cone EJ, Wstadik AT, Schoendorfer D, Joseph RE Jr. Sweat testing for cocaine, codeine and metabolites by gas chromatography-mass spectrometry. J Chromatogr B Biomed Sci Appl 1999;733:247-64
20. Joseph RE Jr, Oyler JM, Wstadik AT, Ohuoha C, Cone EJ. Drug testing with alternative matrices. I. Pharmacological effects and disposition of cocaine and codeine in plasma, sebum and stratum corneum. J Anal Toxicol 1998;22:6-17
21. Joya X, Papaseit E, Civit E, et al. Unsuspected exposure to cocaine in preschool children from a Mediterranean city detected by hair analysis. Ther Drug Monit 2009;31:391-5
22. Garcia-Bournissen F, Nesterenko M, Karaskov T, Koren G. Passive environmental exposure to cocaine in Canadian children. Pediatr Drugs 2009;11:30-2
23. Iwersen S, Schmoldt A, Schulz F, Puschel K. Evidence of gestational heroin exposure by comparative analysis of fetal and maternal body fluids, tissues, and hair in a heroin-related death. J Anal Toxicol 1998;22:296-8
24. Gray T, Huestis M. Bioanalytical procedures for monitoring in utero drug exposure. Anal Bioanal Chem 2007;388:1455-65
25. Thorspecken J, Skopp G, Potsch L. In vitro contamination of hair by marijuana smoke. Clin Chem 2004;50:596-602
26. Paterson S, Lee S, Cordero R. Analysis of hair after contamination with blood containing cocaine and blood containing benzoylecgonine. Forensic Sci Int 2010;194:94-6
27. Romano G, Barbera N, Lombardo I. Hair testing for drugs of abuse: evaluation of external cocaine contamination and risk of false positives. Forensic Sci Int 2001;123:119-29
28. Ferko AP, Barbieri EJ, DiGregorio GJ, Ruch EK. The accumulation and disappearance of cocaine and benzoylecgonine in rat hair following prolonged administration of cocaine. Life Sci 1992;51:1823-32
29. Forman R, Scheiderman J, Klein J, Graham K, Greenwald M, Koren G. Accumulation of cocaine in maternal and fetal hair: the dose response curve. Life Sci 1992;50:1333-41
30. Scheidweiler KB, Cone EJ, Moolchan ET, Huestis MA. Dose-related distribution of codeine, cocaine, and metabolites into human hair following controlled oral codeine and subcutaneous cocaine administration. J Pharmacol Exp Ther 2005;313:909-15
31. Rollins DE, Wilkins DG, Kreuger G. Models for studying the cellular processes and barriers to the incorporation of drugs into hair. NIDA Res Monogr 1995;154:235-44
32. Henderson GL. Mechanisms of drug incorporation into hair. Forensic Sci Int 1993;63:19-29
33. Pragst F, Rothe M, Hunger J, Thor S. Structural and concentration effects on the diposition of tricyclic antidepressants in human hair. Forensic Sci Int 1997;84:225-36
34. Girod C, Staub C. Methadone and EDDP in hair from human subjects following a maintenance program: results from a pilot study. Forensic Sci Int 2001;117:175-84
35. Paterson S, Cordero R, McPhillips M, Carman S. Interindividual dose/concentration relationship for methadone in hair. J Anal Toxicol 2003;27:20-3
36. Ditton J, Cooper GAA, Scott KS, Allen DL, Oliver JS, Smith ID. Hair testing for 'ecstacy' (MDMA) in volunteer Scottish drug users. Addict Biol 2000;5:207-13
37. Kikura R, Nakahara Y, Mieczkowski T, Tagliaro F. Hair analysis for drug abuse XV. Disposition of 3,4-methylenedioxy-methamphetamine (MDMA) and its related compounds into rat hair and application to hair analysis for MDMA abuse. Forensic Sci Int 1997;84:165-77
38. Nakahara Y, Kikura R. Hair analysis for drugs of abuse XIII. Effect of structural factors on incorporation of drugs into hair: the incorporation rates of amphetamine analogs. Arch Toxicol 1996;70:841-9
39. Joseph ER, Su TP, Cone EJ. In vitro binding studies of drugs to hair: influence of melanin and lipids on cocaine binding to caucasoid and africoid hair. J Anal Toxicol 1996;20:338-44
40. Knorle R, Schniz E, Feuerstein TJ. Drug accumulation in melanin: an affinity chromatographic study. J Chromatogr B 1998;714:171-9
41. Borges CR, Wilkins DG, Rollins DE. Amphetamine and N-acetylamphetamine incorporation into hair: an investigation of the potential role of drug basicity in hair color bias. J Anal Toxicol 2001;25:221-7
42. Pötsch L, Skopp G, Moeller MR. Influence of pigmentation on the codeine content of hair fibers in guinea pigs. J Forensic Sci 1997;42:1095-8
43. Slawson MH, Wilkins DG, Rollins DE. The incorporation of drugs into hair: relationship of hair color and melanin concentration to phencyclidine incorporation. J Anal Toxicol 1998;22:406-13
44. Scott KS, Nakahara Y. A study into the rate of incorporation of eight benzodiazepines into rat hair. Forensic Sci Int 2003;133:47-56
45. Kulaga V, Velazquez-Armenta Y, Aleksa K, Vergee Z, Koren G. The effect of hair pigment on the incorporation of fatty acid ethyl esters (FAEE). Alcohol Alcoholism 2009;44:287-92
46. Pötsch L, Skopp G, Moeller MR. Biochemical approach on the conservation of drug molecules during hair formation. Forensic Sci Int 1997;84:25-35
47. Smith H, Forshufvud S, Wassen A. Distribution of arsenic in Napoleon's hair. Nature 1962;194:725-6
48. Springfield AC, Cartmell LW, Aufderheide AC, Buikstra J, Ho J. Cocaine and metabolites in the hair of ancient Peruvian coca leaf chewers. Forensic Sci Int 1993;63:269-75
49. Skopp G, Poötsch L, Aderjan R. Experimental investigations on hair fibres as diffusion bridges and opiates as solutes in solution. J Forensic Sci 1996;41:117-20
50. Pötsch L, Moeller MR. On pathways for small molecules into and out of human hair fibres. J Forensic Sci 1996;41:121-5
51. Skopp G, Poötsch L, Moeller MR. On cosmetically treated hair - aspects and pitfalls of interpretation. Forensic Sci Int 1997;84:43-52
52. Dawber R. Hair: its structure and response to cosmetic preparations. Clin Dermatol 1996;14:105-12
53. Jurado C, Kintz P, Menedez M, Repetto M. Influence of cosmetic treatment of hair on drug testing. Int J Leg Med 1997;110:159-63
54. Cajkovac M, Oremovic L, Cajkovac V. The effect of hair colours and perm products on the state of hair. Acta Pharm 1996;46:39-49
55. Pötsch L, Skopp G. Stability of opiates in hair fibers after exposure to cosmetic treatment. Forensic Sci Int 1996;81:95-102
56. Donahue TD, Rhode KA, Berkable DR. Effects of various hair stripping treatments on analytical results. Presented at the SOFT/TIAFT Meeting in Albuquerque, NM, USA, October 5-9, 1998
57. Röhrich J, Zorntlein S, Potsch L, Skopp G, Becker J. Effect of the shampoo Ultra Clean on drug concentrations in human hair. Int J Legal Med 2000;113:102-6
58. Skopp G, Pötsch L, Mauden M. Stability of cannabinoids in hair exposed to sunlight. Clin Chem 2000;46:1846-8
59. Agius R, Kintz P. Guidelines for European workplace drug testing and alcohol testing in hair. Drug Test Analysis 2010;2:367-76
60. Balíková MA, Habrdová V. Hair analysis for opiates: evaluation of washing and incubation procedures. J Chromatogr B 2003;789:93-100
61. Blank DL, Kidwell DA. Decontamination procedures for drugs of abuse in hair: are they sufficient? Forensic Sci Int 1995;70:13-38
62. Pragst F, Balíková MA. State of the art in hair analysis for the detection of drug and alcohol abuse. Clin Chim Acta 2006;370:17-49
63. Baumgartner WA, Hill VA. Sample preparation techniques. Forensic Sci Int 1993;63:121-35; discussion 137-43
64. Stout PR, Ropero-Miller JD, Baylor MR, Mitchell JM. External contamination of hair with cocaine: evaluation of external cocaine contamination and development of performance-testing materials. J Anal Toxicol 2006;30:490-500
65. Eser HP, Pötsch L, Skopp G, Moeller MR. Influence of sample preparation on analytical results: drug analysis [GC/MS] on hair snippets versus hair powder using various extraction methods. Forensic Sci Int 1997;84:271-9
66. Miyaguchi H, Kakuta M, Iwata YT, et al. Development of a micropulverized extraction method for rapid toxicological analysis of methamphetamine in hair. J Chromatogr A 2007;1163:43-8
67. Miyaguchi H, Takahashi H, Ohashi T, et al. Rapid analysis of methamphetamine in hair by micropulverized extraction and microchip-based competitive ELISA. Forensic Sci Int 2009;184:1-5
68. Sachs H. History of hair analysis. Forensic Sci Int 1997;84:7-16
69. Baumgartner AM, Jones PF, Baumgartner WA, Black CT. Radioimmunoassay of hair for determining opiate-abuse histories. J Nuclear Med 1979;20:748-52
70. Arnold W. RIA analysis of head hair for narcotics and substitutes. J Clin Chem-Clin Biochem 1986;24:797-8
71. Sachs H, Kintz P. Review. Testing for drugs in hair. Critical review of chromatographic procedures since 1992. J Chromatogr B 1998;713:147-61
72. Uhl M. Determination of drugs in hair using GC/MS/MS. Forensic Sci Int 1997;84:281-94
73. Kronstrand R, Nystrom I, Strandberg J, Druid H. Screening for drugs of abuse in hair with ion spray LC-MS-MS. Forensic Sci Int 2004;145:183-90
74. Hegstad S, Khiabani HZ, Kristoffersen L, Kunøe N, Lobmaier PP, Christophersen AS. Drug screening of hair by liquid chromatographytandem mass spectrometry. J Anal Toxicol 2008;32:364-72
75. Tabernero MJ, Felli ML, Bermejo AM, Chiarotti M. Determination of ketamine and amphetamines in hair by LC-MS-MS. Anal Bioanal Chem 2009;395:2547-57
76. Kharbouche H, Spokert F, Troxler S, Augsburger M, Mangin P, Staub C. Development and validation of a gas chromatography-negative chemical ionization tandem mass spectrometry method for the determination of ethyl glucuronide in hair and its application to forensic toxicology. J Chromatogr B Analyt Technol Biomed Life Sci 2009;877:2337-43
77. Chiarotti M. Overview on extraction procedures. Forensic Sci Int 1993;63:161-70
78. Cirimele V, Kintz P, Mangin P. Comparison of different extraction procedures for drugs in hair of drug addicts. Biomed Chromatogr 1996;10:179-182
79. Skender L, Karacić V, Brcić I, Bagarić A. Quantitative determination of amphetamines, cocaine, and opiates in human hair by gas chromatrography/mass spectrometry. Forensic Sci Int 2002;125:120-6
80. Kauert G, Röhrich J. Concentrations of delta 9-tetrahydrocannabinol, cocaine and 6-monoacetylmorphine in hair of drug abusers. Int J Legal Med 1996;108:294-9
81. Miller EI, Wylie FM, Oliver JS. Simultaneous detection and quantification of amphetamines, diazepam and its metabolites, cocaine and its metabolites, and opiates in hair by LC-ESI-MS-MS using a single extraction method. J Anal Toxicol 2008;32:457-69
82. Cordero R, Paterson S. Simultaneous quantification of opiates, amphetamines, cocaine and metabolites and diazepam and metabolite in a single hair sample using GC-MS. J Chromatogr B Analyt Technol Biomed Life Sci 2007;850:423-31
83. Cooper GAA, Allen DL, Scott KS, Oliver JS, Ditton J, Smith ID. Hair analysis: self-reported use of 'speed' and 'ecstasy' compared with laboratory findings. J Forensic Sci 2000;45:400-6
84. Kintz P, Cirimele V. Interlaboratory comparison of quantitative determination of amphetamine and related compounds in hair samples. Forensic Sci Int 1997;84:151-6
85. Moore C, Rana S, Coulter C, Feyerherm F, Prest H. Application of two-dimensional gas chromatography with electron capture chemical ionization mass spectrometry to the detection of 11-nor-D9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) in hair. J Anal Toxicol 2006;30:171-7
86. Huestis MA, Gustafson RA, Moolchan ET, et al. Cannabinoid concentrations in hair from documented cannabis users. Forensic Sci Int 2007;169:129-36
87. Bourland JA, Hayes EF, Kelly RC, Sweeney SA, Hatab MM. Quantitation of cocaine, benzoylecgonine, cocaethylene, methylecgonine, and norcocaine in human hair by positive ion chemical ionization (PICI) gas chromatography-tandem mass spectrometry. J Anal Toxicol 2000;24:489-95
88. Girod C, Staub C. Analysis of drugs of abuse in hair by automated solid-phase extraction, GC/EI/MS and GC ion trap/CI/MS. Forensic Sci Int 2000;107:261-71
89. Kintz P, Cirimele V, Edel Y, Jamey C, Mangin P. Hair analysis for buprenorphine and its dealkylated metabolite by RIA and confirmation by LC/ECD. J Forensic Sci 1994;39:1497-503
90. Marsh A, Evans MB. Radioimmunoassay of drugs of abuse in hair. Part 1: Methadone in human hair, method adaptation and the evaluation of decontamination procedures. J Pharm Biomed Anal 1994;12:1123-30
91. Balabanova S, Wolf H. Determination of methadone in human hair by radioimmunoassay. Z Rechtsmed 1989;102:1-4
92. Spiehler V. Hair analysis by immunological methods from the beginning to 2000. Forensic Sci Int 2000;107:249-59
93. Cooper G, Wilson L, Reid C, Baldwin D, Hand C, Spiehler V. Validation of the Cozart® microplate ELISA for detection of opiates in hair. J Anal Toxicol 2003;27:581-6
94. Cooper G, Wilson L, Reid C, Baldwin D, Hand C, Spiehler V. Comparison of Cozart® microplate ELISA and GC-MS detection of methadone and metabolites in human hair. J Anal Toxicol 2005;29:678-81
95. Pujol ML, Cirimele V, Tritsch PJ, Villain M, Kintz P. Evaluation of the IDS One-Step ELISA kits for the detection of illicit drugs in hair. Forensic Sci Int 2007;170:189-92
96. Tsanaclis L, Wicks JF. Patterns in drug use in the United Kingdom as revealed through analysis of hair in a large population sample. Forensic Sci Int 2007;170:121-8
97. Pelander A, Ristimaa J, Rasanen I, Vuori E, Ojanperä I. Screening for basic drugs in hair of drug addicts by liquid chromatography/time-of-flight mass spectrometry. Ther Drug Monit 2008;30:717-24
98. Moore C, Coulter C, Crompton K. Determination of cocaine, benzoylecgonine, cocaethylene and norcocaine in human hair using solid-phase extraction and liquid chromatography with tandem mass spectrometric detection. J Chromatogr B 2007;859:208-12
99. 9-THC-COOH. Forensic Sci Int 2002;128:66-78
100. Vogliardi S, Favretto D, Frison G, Ferrara SD, Sereglia R, Traldi P. A fast screening MALDI method for the detection of cocaine and its metabolites in hair. J Mass Spectrom 2009;44:18-24
101. Pozo OJ, Deventer K, Van Eenoo P, Rubens R, Delbeke FT. Quantification of testosterone undecanoate in human hair by liquid chromatographytandem mass spectrometry. Biomed Chromatogr 2009;23:873-80
102. Shen M, Xiang P, Shen B, Bu J, Wang M. Physiological concentrations of anabolic steroids in human hair. Forensic Sci Int 2009;184:32-6
103. Gaillard Y, Pépin G. Testing hair for pharmaceuticals. J Chromatogr B Biomed Sci Appl 1999;733:231-46
104. Nakahara Y. Hair analysis for abused and therapeutic drugs. J Chromatogr B Biomed Sci Appl 1999;733:161-80
105. Nielsen MK, Johansen SS, Dalsgaard PW, Linnet K. Simultaneous screening and quantification of 52 common pharmaceuticals and drugs of abuse in hair using UPLC-TOF-MS. Forensic Sci Int 2010;196:85-92
106. Musshoff F, Madea B. Analytical pitfalls in hair testing. Anal Bioanal Chem 2007;388:1475-94
107. Kintz P. Testing for anabolic steroids in hair: a review. Leg Med 2003;5:S29-S33
108. Bush DM. The U.S. Mandatory Guidelines for Federal Workplace Drug Testing Programs: current status and future considerations. Forensic Sci Int 2008;174:111-9
109. ISO/IEC 17025: 2005 Incorporating Corrigendum No.1. Published under the authority of the Standards Policy and Strategy Committee on June 2005, ISBN 0 580 46330 3
110. ILAC-G19: 2002 Guidelines for Forensic Science Laboratories. See http://www.ilac.org/documents/g19_2002.pdf (last checked 27 February 2011)
111. Cooper GAA, Paterson S, Osselton MD. The United Kingdom and Ireland Association of Forensic Toxicologists Forensic toxicology laboratory guidelines (2010). Sci Justice 2010;50:166-76
112. Malkoc E, Neuteboom W. The current status of forensic science laboratory accreditation in Europe. Forensic Sci Int 2007;167:121-6
113. Cooper GAA, Moeller M, Kronstrand R. Current status of accreditation for drug testing in hair. Forensic Sci Int 2008;176:9-12
114. Personal communication - experience of the author dated 27th February 2011
115. Sachs H. Quality control by the Society of Hair Testing. Forensic Sci Int 1997;84:145-50
116. Jurado C, Sachs H. Proficiency test for the analysis of hair for drugs of abuse, organized by the Society of Hair Testing. Forensic Sci Int 2003;133:175-8
117. ISO/IEC 17043: 2010 Conformity assessment - General requirements for proficiency testing. See http://www.iso.org (last checked 14 July 2011) Published 31 May 2010, ISBN 0 580 56522 9
118. ISO Guide 34: 2009 General requirements for competence of reference material producers. See http://www.iso.org (last checked 14 July 2011) Published 20 November 2009
119. Lee S, Park Y, Yang W, et al. Estimation of the measurement uncertainty of methamphetamine and amphetamine in hair analysis. Forensic Sci Int 2009;185:59-66
120. Lee S, Park Y, Yang W, et al. Development of a reference material using methamphetamine abusers' hair samples for the determination of methamphetamine and amphetamine in hair. J Chromatogr B 2008;865:33-9
121. Human Tissue Act 2004. Office of Public Sector Information website. See http://www.opsi.gov.uk/acts/acts2004/ukpga_20040030_en_1 (last checked 27 February 2011)
122. Human Tissue (Scotland) Act 2006. Office of Public Sector Information website. See http://www.opsi.gov.uk/legislation/scotland/acts2006/asp_20060004_en_1 (last checked 27 February 2011)
123. European Laboratory Guidelines for Legally Defensible Workplace Drug Testing. Version 1.0, 2002. See www.ewdts.org/guidelines (last checked February 2011)
124. Mandatory Guidelines for Federal Workplace Drug Testing Programs. SAMHSA September 1, 1994. See www.workplace.samhsa.gov (last checked 27 February 2011)
125. World Anti-Doping Code - 2007 Code Amendments. 1 June 2007, World Anti-Doping Agency Code Version 2.0. See www.wada-ama.org (last checked 27 February 2011)
126. SOFT/AAFS Forensic Toxicology Laboratory Guidelines. 2006 version. See www.soft-tox.org (last checked 27 February 2011)
127. Peters FT, Maurer HH. Bioanalytical method validation and its implications for forensic and clinical toxicology - a review. Accred Qual Assur 2002;7:441-9
128. Peters FT, Drummer OH, Musshoff F. Validation of new methods. Forensic Sci Int 2007;165:216-24
129. Cone EJ. Legal, workplace, and treatment drug testing with alternate biological matrices on a global scale. Forensic Sci Int 2001;121:7-15
130. Caplan YH, Goldberger BA. Alternative specimens for workplace drug testing. J Anal Toxicol 2001;25:396-9
131. Tagliaro F, De Battisti Z, Lubli G, Neri C, Manetto G, Marigo M. Integrated use of hair analysis to investigate the physical fitness to obtain the driving licence: a casework study. Forensic Sci Int 1997;84:129-35
132. Montagna M, Stramesi C, Vignali C, Groppi A, Polettini A. Simultaneous hair testing for opiates, cocaine, and metabolites by GC-MS: a survey of applicants for driving licenses with a history of drug use. Forensic Sci Int 2000;107:157-67
133. Polla M, Stramesi C, Pichini S, Palmi I, Vignali C, Dall'Olio G. Hair testing is superior to urine to disclose cocaine consumption in driver's licence regranting. Forensic Sci Int 2009;189:e41-3
134. Moeller MR, Fey P, Sachs H. Hair analysis as evidence in forensic cases. Forensic Sci Int 1993;63:43-53
135. Kintz P. Value of hair analysis in postmortem toxicology. Forensic Sci Int 2004;142:127-34
136. Paterson S, Cordero R, Stearns E. Chronic drug use confirmed by hair analysis: its role in understanding both the medical cause of death and the circumstances surrounding the death. J Forensic Leg Med 2009;16:143-7
137. Koren G, Hutson J, Dareri J. Novel methods for the detection of drug and alcohol exposure during pregnancy: implications for maternal and child health. Clin Pharmacol Ther 2008;83:520-2
138. Huestis MA, Choo RE. Drug abuse's smallest victims: in utero drug exposure. Forensic Sci Int 2002;128:20-30
139. Lozano J, García-Algar O, Vall O, de la Torre R, Scaravelli G, Pichini S. Biological matrices for the evaluation of in utero exposure to drugs of abuse. Ther Drug Monit 2007;29:711-34
140. Brewer C. Recent developments in maintenance prescribing and monitoring in the United Kingdom. Bull NY Acad Med: J Urban Health 1995;72:359-70
141. McPhillips MA, Strang J, Barnes TRE. Hair Analysis. New laboratory ability to test for substance use. Br J Psych 1998;173:287-90
142. Kintz P, Villain M, Cirimele V. Chemical abuse in the elderly: evidence from hair analysis. Ther Drug Monit 2008;30:207-11
143. Scott KS. The use of hair as a toxicological tool in DFC casework. Sci Justice 2009;49:229-308
144. Kintz P. Bioanalytical procedures for detection of chemical agents in hair in the case of drug-facilitated crimes. Anal Bioanal Chem 2007;388:1467-74
145. Concheiro M, Cruz A, Mon M, et al. Ethylglucuronide determination in urine and hair from alcohol withdrawal patients. J Anal Toxicol 2009;33:155-61
146. Nakahara Y, Kikura R, Yasuhara M, Mukai T. Hair analysis for drug abuse XIV. Identification of substances causing acute poisoning using hair root. I. Methamphetamine. Forensic Sci Int 1997;84:157-64
147. Takayama N, Tanaka S, Hayakawa K. Determination of stimulants in a single human hair sample by high-performance liquid chromatographic method with chemiluminescence detection. Biomed Chromatogr 1997;11:25-8
148. Nakahara Y, Kikura R. Hair analysis for drugs of abuse. XVIII. 3,4-methylenedioxymethamphetamine (MDMA) disposition in hair roots and use in identification of acute poisoning. Biol Pharm Bull 1997;20:969-72
149. Cooper GAA. Application of solid-phase extraction for the analysis of drugs in biological matrices. Thesis submitted to the Department of Forensic Medicine and Science, University of Glasgow, in fulfilment of the degree of Doctor of Philosophy, 1999
150. Scott KS. An evaluation of the use of supercritical fluid extraction techniques to recover drugs from biological matrices. Thesis submitted in accordance with the University of Glasgow for the Degree of Doctor of Philosophy, Department of Forensic Medicine and Science, 1998
151. Kintz P, Evans J, Villain M, Salquebre G, Cirimele V. Hair analysis for diphenydramine after surreptitious administration to a child. Forensic Sci Int 2007;173:171-4
152. Kintz P, Villain M, Cirimele V. Determination of trimeprazine-facilitated sedation in children by hair analysis. J Anal Toxicol 2006;30:400-2
153. McClure RJ, Davis PM, Meadow SR, Sibert JR. Epidemiology of Munchausen syndrome by proxy, non-accidental poisoning, and non-accidental suffocation. Arch Dis Child 1996;75:57-61
154. Kintz P, Eans J, Villain M, Cirimele V. Interpretation of hair findings in children after methadone poisoning. Forensic Sci Int 2010;196:51-4
155. Couper FJ, Chopra K, Pierre-Louis ML. Fatal methadone intoxication in an infant. Forensic Sci Int 2005;153:71-3
156. Yegles M, Labarthe A, Auwärter V, et al. Comparison of ethyl glucuronide and fatty acid ethyl ester concentrations in hair of alcoholics, social drinkers and teetotallers. Forensic Sci Int 2004;145:167-73
157. Kerekes I, Yegles M, Grimm U, Wennig R. Ethyl glucuronide determination: head hair versus non-head hair. Alcohol Alcohol 2009;44:62-6
158. De Giovanni N, Donadio G, Chiarotti M. Ethanol contamination leads to fatty acid ethyl esters in hair samples. J Anal Toxicol 2008;32:156-9
159. Tsatsakis AM. Judicial applications of hair testing for addicts in Crete: sectional hair analysis of heavy heroin abusers. J Clin For Med 1998;5:109-13
160. Huestis MA. Judicial acceptance of hair tests for substances of abuse in the United States courts: scientific, forensic, and ethical Aspects. Ther Drug Monit 1996;18:456-9
161. Pounder DJ. The case of Dr. Shipman. Am J Forensic Med Pathol 2003;24:219-26
162. Chatterton C. Operation PARIS - The Shannon Matthews case. Presented at the 50th Anniversary Meeting of Forensic Toxicology at the Department of Forensic Medicine and Science, University of Glasgow - joint meeting with the 1st annual meeting of the UK and Ireland Forensic Toxicology Network. Glasgow, 26 March 2009
163. LeBeau MA, Montgomery MA. Considerations on the utility of hair analysis for cocaine. J Anal Toxicol 2009;33:343-4
164. Pragst F, Sachs H, Kintz P. Hair analysis for cocaine continues to be a valuable tool in forensic and clinical toxicology. J Anal Toxicol 2010;34:354-6
165. Lee S, Cordero R, Paterson S. Distribution of 6-monoacetylmorphine and morphine in head and pubic hair from heroin-related deaths. Forensic Sci Int 2009;183:74-7
166. Uhl M, Scheufler F. Effects of hair colour on the drug incorporation into human hair. Annales de Toxicologie Analytique 2005;XV11:279-84
167. Garcia-Bournissen F, Moller M, Nesterenko M, Karaskov T, Koren G. Pharmacokinetics of disappearance of cocaine from hair after discontinuation of drug use. Forensic Sci Int 2009;189:24-7
168. Felli M, Martello S, Marsili R, Chiarotti M. Disappearance of cocaine from human hair after abstinence. Forensic Sci Int 2005;154:96-8