-
1
-
-
0037584241
-
Dietary requirements for reproduction: II. The existence of a specific vitamin for reproduction
-
Sure, B. Dietary requirements for reproduction: II. The existence of a specific vitamin for reproduction. J. Biol. Chem., 1924, 58 (3), 693-709.
-
(1924)
J. Biol. Chem
, vol.58
, Issue.3
, pp. 693-709
-
-
Sure, B.1
-
2
-
-
27644463421
-
Biotechnological production and application of vitamin E: Current state and prospects
-
Valentin, H.E.; Qi, Q. Biotechnological production and application of vitamin E: current state and prospects. Appl. Microbiol. Biotechnol., 2005, 68 (4), 436-444.
-
(2005)
Appl. Microbiol. Biotechnol
, vol.68
, Issue.4
, pp. 436-444
-
-
Valentin, H.E.1
Qi, Q.2
-
3
-
-
0036687017
-
Palmtocotrienols: New antioxidants for the new millennium
-
Sundram, K.; Thiagarajan, T.; Gapor, A.; Basiron, Y. Palmtocotrienols: new antioxidants for the new millennium. Inform., 2002, 13, 634-640.
-
(2002)
Inform
, vol.13
, pp. 634-640
-
-
Sundram, K.1
Thiagarajan, T.2
Gapor, A.3
Basiron, Y.4
-
4
-
-
0025761230
-
Free radical recycling and intramembrane mobility in the antioxidant properties of α-tocopherol and α-tocotrienol
-
Serbinova, E.; Kagan, V.; Han, D.; Packer, L. Free radical recycling and intramembrane mobility in the antioxidant properties of α-tocopherol and α-tocotrienol. Free Radic. Biol. Med., 1991, 10 (5), 263-275.
-
(1991)
Free Radic. Biol. Med
, vol.10
, Issue.5
, pp. 263-275
-
-
Serbinova, E.1
Kagan, V.2
Han, D.3
Packer, L.4
-
5
-
-
0030950694
-
Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo
-
He, L.; Mo, H, Hadisusilo, S.; Qureshi, A.A.; Elson, C.E. Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo. J. Nutr., 1997, 127 (5), 668-674.
-
(1997)
J. Nutr
, vol.127
, Issue.5
, pp. 668-674
-
-
He, L.1
Mo, H.2
Hadisusilo, S.3
Qureshi, A.A.4
Elson, C.E.5
-
6
-
-
0034193155
-
Vitamin E: Non-antioxidant roles
-
Azzi, A.; Stocker, A. Vitamin E: non-antioxidant roles. Prog. Lipid Res., 2000, 39 (3), 231-255.
-
(2000)
Prog. Lipid Res
, vol.39
, Issue.3
, pp. 231-255
-
-
Azzi, A.1
Stocker, A.2
-
7
-
-
0027474439
-
Absorption, lipoprotein transport and regulation of plasma concentrations of vitamin E in humans
-
Kayden, H.J.; Traber, M.G. Absorption, lipoprotein transport and regulation of plasma concentrations of vitamin E in humans. J. Lipid Res., 1993, 34 (3), 343-358.
-
(1993)
J. Lipid Res
, vol.34
, Issue.3
, pp. 343-358
-
-
Kayden, H.J.1
Traber, M.G.2
-
8
-
-
0035140716
-
Pharmacokinetics and bioavailability of alpha-, gamma-, and delta-tocotrienols under different food status
-
Yap, S.P.; Yuen, K.H.; Wong, J.W. Pharmacokinetics and bioavailability of alpha-, gamma-, and delta-tocotrienols under different food status. J. Pharm. Pharmacol., 2001, 53 (1), 67-71.
-
(2001)
J. Pharm. Pharmacol
, vol.53
, Issue.1
, pp. 67-71
-
-
Yap, S.P.1
Yuen, K.H.2
Wong, J.W.3
-
9
-
-
34347371216
-
Vitamin E
-
Mustacich, D.J.; Bruno, R.S.; Traber, M.G. Vitamin E. Vitam. Horm., 2007, 76, 1-21.
-
(2007)
Vitam. Horm
, vol.76
, pp. 1-21
-
-
Mustacich, D.J.1
Bruno, R.S.2
Traber, M.G.3
-
10
-
-
0033037413
-
Vitamin E: Function and metabolism
-
Brigelius-Flohe, R.; Traber, M.G. Vitamin E: function and metabolism. FASEB. J., 1999, 13 (10), 1145-1155.
-
(1999)
FASEB. J
, vol.13
, Issue.10
, pp. 1145-1155
-
-
Brigelius-Flohe, R.1
Traber, M.G.2
-
11
-
-
0035113436
-
Alpha- and gamma-tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine
-
Lodge, J.K.; Ridlington, J.; Leonard, S.; Vaule, H.; Traber, M.G. Alpha- and gamma-tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine. Lipids, 2001, 36(1), 43-48.
-
(2001)
Lipids
, vol.36
, Issue.1
, pp. 43-48
-
-
Lodge, J.K.1
Ridlington, J.2
Leonard, S.3
Vaule, H.4
Traber, M.G.5
-
12
-
-
0030015296
-
The chemistry and antioxidant properties of tocopherols and tocotrienols
-
Kamal-Eldin, A.; Appelqvist, L.A. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids, 1996, 31 (7) 671-701.
-
(1996)
Lipids
, vol.31
, Issue.7
, pp. 671-701
-
-
Kamal-Eldin, A.1
Appelqvist, L.A.2
-
13
-
-
0022001846
-
Effect of phytyl side chain of vitamin E on iots antioxidant activity
-
Niki, E.; Kawakami, A.; Satio, M.; Yamamto, Y.; Tsuchiya, J.; Kamiya, Y. Effect of phytyl side chain of vitamin E on iots antioxidant activity. J. Biol. Chem., 1985, 260 (4), 2191-2196.
-
(1985)
J. Biol. Chem
, vol.260
, Issue.4
, pp. 2191-2196
-
-
Niki, E.1
Kawakami, A.2
Satio, M.3
Yamamto, Y.4
Tsuchiya, J.5
Kamiya, Y.6
-
14
-
-
0024955813
-
Vitamin E as an in vitro and in vivo antioxidant
-
Burton, G.W.; Ingold, K.U. Vitamin E as an in vitro and in vivo antioxidant. Ann. N. Y. Acad. Sci., 1989, 570, 7-22.
-
(1989)
Ann. N. Y. Acad. Sci
, vol.570
, pp. 7-22
-
-
Burton, G.W.1
Ingold, K.U.2
-
15
-
-
0027324656
-
Influence of palm oil or its tocotrienol-rich fraction on the lipid peroxidation potential of rat liver mitochondria and microsomes
-
Nesaretnam, K.; Devasagayam, T.P.; Singh, B.B.; Basiron, Y. Influence of palm oil or its tocotrienol-rich fraction on the lipid peroxidation potential of rat liver mitochondria and microsomes. Biochem. Mol. Biol. Int., 1993, 30 (1), 159-167.
-
(1993)
Biochem. Mol. Biol. Int
, vol.30
, Issue.1
, pp. 159-167
-
-
Nesaretnam, K.1
Devasagayam, T.P.2
Singh, B.B.3
Basiron, Y.4
-
16
-
-
0025761230
-
Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol
-
Serbinova, E.; Kagan, V.; Han, D.; Packer, L. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic. Biol. Med., 1991, 10 (5), 263-275.
-
(1991)
Free Radic. Biol. Med
, vol.10
, Issue.5
, pp. 263-275
-
-
Serbinova, E.1
Kagan, V.2
Han, D.3
Packer, L.4
-
17
-
-
84856582504
-
Toctrienol as a potential anticancer agent
-
Ling, T.M.; Luk, S.U.; Al-Ejeh, F.; Khanna, K.K. Toctrienol as a potential anticancer agent. Carcinogenesis, 2012, 33(5), 233-239.
-
(2012)
Carcinogenesis
, vol.33
, Issue.5
, pp. 233-239
-
-
Ling, T.M.1
Luk, S.U.2
Al-Ejeh, F.3
Khanna, K.K.4
-
18
-
-
0033872034
-
Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells
-
McIntyre, B.S.; Briski, K.P.; Gapor, A.; Sylvester, P.W. Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells. Proc. Soc. Exp. Biol. Med., 2000, 224 (4), 292-301.
-
(2000)
Proc. Soc. Exp. Biol. Med
, vol.224
, Issue.4
, pp. 292-301
-
-
McIntyre, B.S.1
Briski, K.P.2
Gapor, A.3
Sylvester, P.W.4
-
19
-
-
0024406504
-
Studies on the biological activity of tocotrienols
-
Komiyama, K.; Iizuka, K.; Yamaoka, M.; Watanabe, H.; Tsuchiya, N.; Umezawa, I. Studies on the biological activity of tocotrienols. Chem. Pharm. Bull., 1989, 37 (5), 1369-1371.
-
(1989)
Chem. Pharm. Bull
, vol.37
, Issue.5
, pp. 1369-1371
-
-
Komiyama, K.1
Iizuka, K.2
Yamaoka, M.3
Watanabe, H.4
Tsuchiya, N.5
Umezawa, I.6
-
20
-
-
63049131505
-
Inhibition of proliferation and induction of apoptosis by gamma-tocotrienol in human colon carcinoma HT-29 cells
-
Xu, W.L.; Liu, J.R.; Liu, H.K.; Qi, K.Y.; Sun, X.R.; Sun, W.G. Inhibition of proliferation and induction of apoptosis by gamma-tocotrienol in human colon carcinoma HT-29 cells. Nutrition, 2009, 25(5), 555-566.
-
(2009)
Nutrition
, vol.25
, Issue.5
, pp. 555-566
-
-
Xu, W.L.1
Liu, J.R.2
Liu, H.K.3
Qi, K.Y.4
Sun, X.R.5
Sun, W.G.6
-
21
-
-
77951210231
-
Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of Her-2/neu expression
-
Pierpaoli, E.; Viola, V.; Pilolli, F.; Piroddi, M.; Galli, F.; Provinciali, M. Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of Her-2/neu expression. Life Sci., 2010, 86(17-18), 668-675.
-
(2010)
Life Sci
, vol.86
, Issue.17-18
, pp. 668-675
-
-
Pierpaoli, E.1
Viola, V.2
Pilolli, F.3
Piroddi, M.4
Galli, F.5
Provinciali, M.6
-
22
-
-
73349116547
-
Anti-proliferative effects of gamma-tocotrienol on mammary tumour cells are associated with suppression of cell cycle progression
-
Samant, G.V.; Wali, V.B.; Sylvester, P.W. Anti-proliferative effects of gamma-tocotrienol on mammary tumour cells are associated with suppression of cell cycle progression. Cell Prolif., 2010, 43(1), 77-83.
-
(2010)
Cell Prolif
, vol.43
, Issue.1
, pp. 77-83
-
-
Samant, G.V.1
Wali, V.B.2
Sylvester, P.W.3
-
23
-
-
33745176559
-
Tocotrienol-rich fraction of palm oil induces cell cycle arrest and apoptosis selectively in human prostate cancer cells
-
Srivastava, J.K.; Gupta, S. Tocotrienol-rich fraction of palm oil induces cell cycle arrest and apoptosis selectively in human prostate cancer cells. Biochem. Biophys. Res. Commun., 2006, 346 (2), 447-453.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.346
, Issue.2
, pp. 447-453
-
-
Srivastava, J.K.1
Gupta, S.2
-
24
-
-
33746774177
-
Down-regulation of telomerase activity in DLD-1 human colorectal adenocarcinoma cells by tocotrienol
-
Eitsuka, T.; Nakagawa, K.; Miyazawa, T. Down-regulation of telomerase activity in DLD-1 human colorectal adenocarcinoma cells by tocotrienol. Biochem. Biophys. Res. Commun., 2006, 348 (1),170-175.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.348
, Issue.1
, pp. 170-175
-
-
Eitsuka, T.1
Nakagawa, K.2
Miyazawa, T.3
-
25
-
-
67649399439
-
Evidence of gamma-tocotrienol as an apoptosis-inducing, invasion-suppressing, and chemotherapy drug-sensitizing agent in human melanoma cells
-
Chang, P.N.; Yap, W.N.; Lee, D.T.; Ling, M.T.; Wong, Y.C.; Yap, Y.L. Evidence of gamma-tocotrienol as an apoptosis-inducing, invasion-suppressing, and chemotherapy drug-sensitizing agent in human melanoma cells. Nutr. Cancer, 2009, 61(3), 357-366.
-
(2009)
Nutr. Cancer
, vol.61
, Issue.3
, pp. 357-366
-
-
Chang, P.N.1
Yap, W.N.2
Lee, D.T.3
Ling, M.T.4
Wong, Y.C.5
Yap, Y.L.6
-
26
-
-
0025952954
-
Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites
-
Crowell, P.L.; Chang, R.R.; Ren, Z.B.; Elson, C.E.; Gould, M.N. Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites. J. Biol. Chem., 1991, 266 (26), 17679-17685.
-
(1991)
J. Biol. Chem
, vol.266
, Issue.26
, pp. 17679-17685
-
-
Crowell, P.L.1
Chang, R.R.2
Ren, Z.B.3
Elson, C.E.4
Gould, M.N.5
-
27
-
-
34047096023
-
Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo
-
McAnally, J.A.; Gupta, J.; Sodhani, S.; Bravo, L.; Mo, H. Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo. Exp. Biol. Med (Maywood)., 2007, 232(4), 523-531.
-
(2007)
Exp. Biol. Med (Maywood)
, vol.232
, Issue.4
, pp. 523-531
-
-
McAnally, J.A.1
Gupta, J.2
Sodhani, S.3
Bravo, L.4
Mo, H.5
-
28
-
-
78649319062
-
Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling
-
Park, S.K.; Sanders, B.G.; Kline, K. Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling. Breast Cancer Res. Treat., 2010, 124(2), 361-375.
-
(2010)
Breast Cancer Res. Treat
, vol.124
, Issue.2
, pp. 361-375
-
-
Park, S.K.1
Sanders, B.G.2
Kline, K.3
-
29
-
-
77953285620
-
Synergistic anticancer effects of combined gamma-tocotrienol and celecoxib treatment are associated with suppression in Akt and NFkappaB signaling
-
Shirode, A.B.; Sylvester, P.W. Synergistic anticancer effects of combined gamma-tocotrienol and celecoxib treatment are associated with suppression in Akt and NFkappaB signaling. Biomed. Pharmacother., 2010, 64(5), 327-332.
-
(2010)
Biomed. Pharmacother
, vol.64
, Issue.5
, pp. 327-332
-
-
Shirode, A.B.1
Sylvester, P.W.2
-
30
-
-
84856057025
-
The therapeutic potential of TRAIL receptor signalling in cancer cells
-
Yerbes, R.; Palacios, C; López-Rivas, A. The therapeutic potential of TRAIL receptor signalling in cancer cells. Clin. Transl. Oncol., 2011, 13(12), 839-847.
-
(2011)
Clin. Transl. Oncol
, vol.13
, Issue.12
, pp. 839-847
-
-
Yerbes, R.1
Palacios, C.2
López-Rivas, A.3
-
31
-
-
80051778368
-
Mitochondria in cancer: At the crossroads of life and death
-
Fogg, V.C.; Lanning, N.J.; Mackeigan, J.P. Mitochondria in cancer: at the crossroads of life and death. Chin. J. Cancer, 2011, 30(8), 526-539.
-
(2011)
Chin. J. Cancer
, vol.30
, Issue.8
, pp. 526-539
-
-
Fogg, V.C.1
Lanning, N.J.2
Mackeigan, J.P.3
-
32
-
-
84860124421
-
Strategic Role for mitochondria in Alzheimer's Disease and cancer
-
Hedskog, L.; Zhang, S.; Ankarcrona, M. Strategic Role for mitochondria in Alzheimer's Disease and cancer. Antioxid., Redox Signal., 2012, 16(12), 1476-1491.
-
(2012)
Antioxid., Redox Signal
, vol.16
, Issue.12
, pp. 1476-1491
-
-
Hedskog, L.1
Zhang, S.2
Ankarcrona, M.3
-
33
-
-
3843146442
-
Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association
-
Agarwal, M.K.; Agarwal, M.L.; Athar, M.; Gupta, S. Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association. Cell Cycle, 2004, 3 (2), 205-211.
-
(2004)
Cell Cycle
, vol.3
, Issue.2
, pp. 205-211
-
-
Agarwal, M.K.1
Agarwal, M.L.2
Athar, M.3
Gupta, S.4
-
34
-
-
33846998312
-
Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis
-
Ahn, K.S.; Sethi, G.; Krishnan, K.; Aggarwal, B.B. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. J. Biol. Chem., 2007, 282 (1), 809-820.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.1
, pp. 809-820
-
-
Ahn, K.S.1
Sethi, G.2
Krishnan, K.3
Aggarwal, B.B.4
-
35
-
-
70349784963
-
Endoplasmic reticulum stress mediates gamma-tocotrienol-induced apoptosis in mammary tumor cells
-
Wali, V.B.; Bachawal, S.V.; Sylvester, P.W. Endoplasmic reticulum stress mediates gamma-tocotrienol-induced apoptosis in mammary tumor cells. Apoptosis, 2009, 14 (11), 1366-1377.
-
(2009)
Apoptosis
, vol.14
, Issue.11
, pp. 1366-1377
-
-
Wali, V.B.1
Bachawal, S.V.2
Sylvester, P.W.3
-
36
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan, D.; Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 1996, 86 (3), 353-364.
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
37
-
-
0030701960
-
Halting angiogenesis suppresses carcinoma cell invasion
-
Skobe, M.; Rockwell, P.; Goldstein, N.; Vosseler, S.; Fusenig, N.E. Halting angiogenesis suppresses carcinoma cell invasion. Nat. Med., 1997, 3 (11), 1222-1227.
-
(1997)
Nat. Med
, vol.3
, Issue.11
, pp. 1222-1227
-
-
Skobe, M.1
Rockwell, P.2
Goldstein, N.3
Vosseler, S.4
Fusenig, N.E.5
-
38
-
-
84859575611
-
Anti-angiogenesis therapy in cancer: Current challenges and future perspectives
-
Shojaei, F. Anti-angiogenesis therapy in cancer: Current challenges and future perspectives. Cancer Lett., 2012, 320(2), 130-137.
-
(2012)
Cancer Lett
, vol.320
, Issue.2
, pp. 130-137
-
-
Shojaei, F.1
-
39
-
-
80255123709
-
Targeting angiogenesis with compounds from the extracellular matrix
-
Belotti, D.; Foglieni, C; Resovi, A.; Giavazzi, R.; Taraboletti, G. Targeting angiogenesis with compounds from the extracellular matrix. Int. J. Biochem. Cell Biol., 2011, 43(12), 1674-1685.
-
(2011)
Int. J. Biochem. Cell Biol
, vol.43
, Issue.12
, pp. 1674-1685
-
-
Belotti, D.1
Foglieni, C.2
Resovi, A.3
Giavazzi, R.4
Taraboletti, G.5
-
40
-
-
34548058897
-
In vivo angiogenesis is suppressed by unsaturated vitamin E
-
Nakagawa, K.; Shibata, A.; Yamashita, S.; Tsuzuki, T.; Kariya, J.; Oikawa, S.; Miyazawa, T. In vivo angiogenesis is suppressed by unsaturated vitamin E. J. Nutr., 2007, 137 (8), 1938-1943.
-
(2007)
J. Nutr
, vol.137
, Issue.8
, pp. 1938-1943
-
-
Nakagawa, K.1
Shibata, A.2
Yamashita, S.3
Tsuzuki, T.4
Kariya, J.5
Oikawa, S.6
Miyazawa, T.7
-
41
-
-
0348013451
-
Vitamin E succinate and cancer treatment: A vitamin E prototype for selective antitumor activity
-
Neuzil, J. Vitamin E succinate and cancer treatment: a vitamin E prototype for selective antitumor activity. Br. J.Cancer, 2003, 89 (10),1822-1826.
-
(2003)
Br. J.Cancer
, vol.89
, Issue.10
, pp. 1822-1826
-
-
Neuzil, J.1
-
42
-
-
0037898519
-
Vitamin E analogues as inducers of apoptosis: Structure-function relation
-
Birringer, M.; EyTina, J.H.; Salvatore, B.A.; Neuzil, J. Vitamin E analogues as inducers of apoptosis: structure-function relation. Br. J. Cancer, 2003, 88 (12), 1948-1955.
-
(2003)
Br. J. Cancer
, vol.88
, Issue.12
, pp. 1948-1955
-
-
Birringer, M.1
Eytina, J.H.2
Salvatore, B.A.3
Neuzil, J.4
-
43
-
-
80155213980
-
Mitochondrially targeted a-tocopheryl succinate is antiangiogenic: Potential benefit against tumor angiogenesis but caution against wound healing
-
Rohlena, J.; Dong, L.F.; Kluckova, K.; Zobalova, R.; Goodwin, J.; Tilly, D.; Stursa, J.; Pecinova, A.; Philimonenko, A.; Hozak, P.; Banerjee, J.; Ledvina, M.; Sen, C.K.; Houstek, J.; Coster, M.J.; Neuzil, J. Mitochondrially targeted a-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing. Antioxid. Redox Signal., 2011, 15(12), 2923-2935.
-
(2011)
Antioxid. Redox Signal
, vol.15
, Issue.12
, pp. 2923-2935
-
-
Rohlena, J.1
Dong, L.F.2
Kluckova, K.3
Zobalova, R.4
Goodwin, J.5
Tilly, D.6
Stursa, J.7
Pecinova, A.8
Philimonenko, A.9
Hozak, P.10
Banerjee, J.11
Ledvina, M.12
Sen, C.K.13
Houstek, J.14
Coster, M.J.15
Neuzil, J.16
-
44
-
-
0028229468
-
The selective antiproliferative effects of alpha-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds
-
Faris, M.W.; Fortuna, M.B.; Everett, C.K.; Smith, J.D.; Trent, D.F.; Djuric, Z. The selective antiproliferative effects of alpha-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds. Cancer Res., 1994, 54 (13), 3346-3351.
-
(1994)
Cancer Res
, vol.54
, Issue.13
, pp. 3346-3351
-
-
Faris, M.W.1
Fortuna, M.B.2
Everett, C.K.3
Smith, J.D.4
Trent, D.F.5
Djuric, Z.6
-
45
-
-
0035342178
-
The suppression of ornithine decarboxylase expression and cell proliferation at the promotion stage of lung tumorigenesis in mice by alpha-tocopheryloxybutyric acid
-
Yano, T.; Yano, Y.; Yajima, S.; Kumadaki, I.; Ichikawa, T.; Otani, S.; Hagiwara, K. The suppression of ornithine decarboxylase expression and cell proliferation at the promotion stage of lung tumorigenesis in mice by alpha-tocopheryloxybutyric acid. Biochem. Pharmacol., 2001, 61 (9), 1177-1181.
-
(2001)
Biochem. Pharmacol
, vol.61
, Issue.9
, pp. 1177-1181
-
-
Yano, T.1
Yano, Y.2
Yajima, S.3
Kumadaki, I.4
Ichikawa, T.5
Otani, S.6
Hagiwara, K.7
-
46
-
-
20144364027
-
Induction of cytotoxicity in human lung adenocarcinoma cells by 6-O-carboxypropyl-alpha-tocotrienol, a redox-silent derivative of alpha-tocotrienol
-
Yano, Y.; Satoh, H.; Fukumoto, K.; Kumadaki, I.; Ichikawa, T.; Yamada, K.; Hagiwara, K.; Yano, T. Induction of cytotoxicity in human lung adenocarcinoma cells by 6-O-carboxypropyl-alpha-tocotrienol, a redox-silent derivative of alpha-tocotrienol. Int. J. Cancer, 2005, 115 (5), 839-846.
-
(2005)
Int. J. Cancer
, vol.115
, Issue.5
, pp. 839-846
-
-
Yano, Y.1
Satoh, H.2
Fukumoto, K.3
Kumadaki, I.4
Ichikawa, T.5
Yamada, K.6
Hagiwara, K.7
Yano, T.8
-
47
-
-
78449243044
-
Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors
-
Behery, F.A.; Elnagar, A.Y.; Akl, M.R.; Wali, V.B.; Abuasal, B.; Kaddoumi, A.; Sylvester, P.W.; El Sayed, K.A. Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors. Bioorg. Med. Chem., 2010, 18(22), 8066-8075.
-
(2010)
Bioorg. Med. Chem
, vol.18
, Issue.22
, pp. 8066-8075
-
-
Behery, F.A.1
Elnagar, A.Y.2
Akl, M.R.3
Wali, V.B.4
Abuasal, B.5
Kaddoumi, A.6
Sylvester, P.W.7
El-Sayed, K.A.8
-
48
-
-
0038548583
-
Molecular regulation of cholesterol biosynthesis: Implications in carcinogenesis
-
Singh, R.P.; Kumar, R.; Kapur, N. Molecular regulation of cholesterol biosynthesis: implications in carcinogenesis. J. Environ. Pathol. Toxicol. Oncol., 2003, 22 (2), 75-92.
-
(2003)
J. Environ. Pathol. Toxicol. Oncol
, vol.22
, Issue.2
, pp. 75-92
-
-
Singh, R.P.1
Kumar, R.2
Kapur, N.3
-
49
-
-
0026747866
-
Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity
-
Kato, K.; Cox, A.D.; Hiasaka, M.M.; Graham, S.M.; Buss, J.E.; Der, C.J. Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. Proc. Natl. Acad. Sci. USA, 1992, 89 (14), 6403-6407.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, Issue.14
, pp. 6403-6407
-
-
Kato, K.1
Cox, A.D.2
Hiasaka, M.M.3
Graham, S.M.4
Buss, J.E.5
Der, C.J.6
-
50
-
-
0035146985
-
Molecular aspects of alpha-tocotrienol antioxidant action and cell signaling
-
Packer, L.; Weber, S.U.; Rimbach, G. Molecular aspects of alpha-tocotrienol antioxidant action and cell signaling. J. Nutr., 2001, 131 (2), 369S-373S.
-
(2001)
J. Nutr
, vol.131
, Issue.2
-
-
Packer, L.1
Weber, S.U.2
Rimbach, G.3
-
51
-
-
0032868926
-
Isoprenoid-mediated inhibition of mevalonate synthesis: Potential application to cancer
-
Elson, C.E.; Peffley, D.M.; Hentosh, P.; Mo, H. Isoprenoid-mediated inhibition of mevalonate synthesis: potential application to cancer. Proc. Soc. Exp. Biol. Med., 1999, 221 (4), 294-311.
-
(1999)
Proc. Soc. Exp. Biol. Med
, vol.221
, Issue.4
, pp. 294-311
-
-
Elson, C.E.1
Peffley, D.M.2
Hentosh, P.3
Mo, H.4
-
52
-
-
0034618369
-
MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
-
Bucher, M.J.; Morisset, J.; Vachon, P.H.; Reed, J.C., Laine, J.; Rivard, N. MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells. J. Cell Biochem., 2000, 79 (3), 355-369.
-
(2000)
J. Cell Biochem
, vol.79
, Issue.3
, pp. 355-369
-
-
Bucher, M.J.1
Morisset, J.2
Vachon, P.H.3
Reed, J.C.4
Laine, J.5
Rivard, N.6
-
53
-
-
0037195142
-
-
Kato-Stankiewicz, J.; Hakimi, I.; Zhi, G.; Zhang, J.; Serebriiskii, I.; Guo, L.; Edamatsu, H.; Koide, H.; Menon S.; Eckl, R.; Sakamuri, S.; Lu, Y.; Chen, Q.Z.; Agarwal, S.; Baumbach, W.R.; Golemis, E.A.; Tamanoi, F.; Khazak, V. Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells. 2002, 99 (22), 14398-14403.
-
(2002)
Inhibitors of Ras/Raf-1 Interaction Identified By Two-hybrid Screening Revert Ras-dependent Transformation Phenotypes In Human Cancer Cells
, vol.99
, Issue.22
, pp. 14398-14403
-
-
Kato-Stankiewicz, J.1
Hakimi, I.2
Zhi, G.3
Zhang, J.4
Serebriiskii, I.5
Guo, L.6
Edamatsu, H.7
Koide, H.8
Menon, S.9
Eckl, R.10
Sakamuri, S.11
Lu, Y.12
Chen, Q.Z.13
Agarwal, S.14
Baumbach, W.R.15
Golemis, E.A.16
Tamanoi, F.17
Khazak, V.18
-
54
-
-
0032939619
-
Rho GTPases are over-expressed in human tumors
-
Fritz, G.; Just, I.; Kaina, B. Rho GTPases are over-expressed in human tumors. Int. J. Cancer, 1999, 81 (5), 682-687.
-
(1999)
Int. J. Cancer
, vol.81
, Issue.5
, pp. 682-687
-
-
Fritz, G.1
Just, I.2
Kaina, B.3
-
55
-
-
0035874879
-
Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors
-
Kusama, T.; Mukai, M.; Iwasaki, T.; Tatsuta, M.; Matsumoto, Y.; Akedo, H.; Nakamura, H. Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. Cancer Res., 2001, 61 (12), 4885-4891.
-
(2001)
Cancer Res
, vol.61
, Issue.12
, pp. 4885-4891
-
-
Kusama, T.1
Mukai, M.2
Iwasaki, T.3
Tatsuta, M.4
Matsumoto, Y.5
Akedo, H.6
Nakamura, H.7
-
56
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall, A. Rho GTPases and the actin cytoskeleton. Science, 1998, 279 (5350), 509-514.
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 509-514
-
-
Hall, A.1
-
57
-
-
0036198699
-
Farnesol and geranylgeraniol: Prevention and reversion of lovastatin-induced effects in NIH3T3 cells
-
Ownby, S.E.; Hohl, R.J. Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells. Lipids, 2002, 37 (2), 185-192.
-
(2002)
Lipids
, vol.37
, Issue.2
, pp. 185-192
-
-
Ownby, S.E.1
Hohl, R.J.2
-
58
-
-
3042623408
-
A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth
-
Martin, SS.; Ridgeway, A.G.; Pinkas, J.; Lu, Y.; Reginato, M.J.; Koh, E.Y.; Michelman, M.; Daley, G.Q.; Brugge, J.S.; Leder, P. A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth. Oncogene, 2004, 23 (26), 4641-4645.
-
(2004)
Oncogene
, vol.23
, Issue.26
, pp. 4641-4645
-
-
Martin, S.S.1
Ridgeway, A.G.2
Pinkas, J.3
Lu, Y.4
Reginato, M.J.5
Koh, E.Y.6
Michelman, M.7
Daley, G.Q.8
Brugge, J.S.9
Leder, P.10
-
59
-
-
0034724679
-
Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells
-
Sen, CK.; Khanna, S.; Roy, S.; Packer, L. Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells. J. Biol. Chem., 2000, 275 (17), 13049-13055.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.17
, pp. 13049-13055
-
-
Sen, C.K.1
Khanna, S.2
Roy, S.3
Packer, L.4
-
60
-
-
4544235743
-
c-Src and cooperating partners in human cancer
-
Ishizawar, R.; Parsons, S.J. c-Src and cooperating partners in human cancer. Cancer Cell, 2004, 6 (3), 209-214.
-
(2004)
Cancer Cell
, vol.6
, Issue.3
, pp. 209-214
-
-
Ishizawar, R.1
Parsons, S.J.2
-
61
-
-
34447316429
-
Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion
-
Tsao, A.S.; He, D.; Saigal, B.; Liu, S., Lee J.J.; Bakkannagari, S.; Ordonez, N.G.; Hong, W.K.; Wistuba, I.; Johnson, F.M. Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion. Mol. Cancer Ther., 2007, 6 (7), 1962-1972.
-
(2007)
Mol. Cancer Ther
, vol.6
, Issue.7
, pp. 1962-1972
-
-
Tsao, A.S.1
He, D.2
Saigal, B.3
Liu, S.4
Lee, J.J.5
Bakkannagari, S.6
Ordonez, N.G.7
Hong, W.K.8
Wistuba, I.9
Johnson, F.M.10
-
62
-
-
65049090994
-
A redox-silent analogue of tocotrienol acts as a potential cytotoxic agent against human mesothelioma cells
-
Kashiwagi, K.; Virgona, N.; Harada, K.; Kido, W.; Yano, Y.; Ando, A.; Hagiwara, K.; Yano, T. A redox-silent analogue of tocotrienol acts as a potential cytotoxic agent against human mesothelioma cells. Life Sci., 2009, 84 (19-20), 650-656.
-
(2009)
Life Sci
, vol.84
, Issue.19-20
, pp. 650-656
-
-
Kashiwagi, K.1
Virgona, N.2
Harada, K.3
Kido, W.4
Yano, Y.5
Ando, A.6
Hagiwara, K.7
Yano, T.8
-
63
-
-
36849023643
-
Enhancement of anticancer effect of alpha-tocotrienol by ether bond in phenolic hydroxy group of chroman ring
-
Yano, T.; Kashiwagi, K.; Yano, Y.; Kumadaki, I.; Yoshimura, K.; Enhancement of anticancer effect of alpha-tocotrienol by ether bond in phenolic hydroxy group of chroman ring. Vitamins, 2007, 81 (suppl), 181.
-
(2007)
Vitamins
, vol.81
, Issue.SUPPL.
, pp. 181
-
-
Yano, T.1
Kashiwagi, K.2
Yano, Y.3
Kumadaki, I.4
Yoshimura, K.5
-
64
-
-
23644433002
-
Contribution of the Src family of kinases to the appearance of malignant phenotypes in renal cancer cells
-
Yonezawa, Y.; Nagashima, Y.; Sato, H.; Virgona, N.; Fukumoto, K.; Shirai, S.; Hagiwara, H.; Seki, T.; Ariga, T.; Senba, H.; Suzuki, K.; Asano, R.; Hagiwara, K.; Yano, T. Contribution of the Src family of kinases to the appearance of malignant phenotypes in renal cancer cells. Mol. Carcinog., 2005, 43 (4), 188-197.
-
(2005)
Mol. Carcinog
, vol.43
, Issue.4
, pp. 188-197
-
-
Yonezawa, Y.1
Nagashima, Y.2
Sato, H.3
Virgona, N.4
Fukumoto, K.5
Shirai, S.6
Hagiwara, H.7
Seki, T.8
Ariga, T.9
Senba, H.10
Suzuki, K.11
Asano, R.12
Hagiwara, K.13
Yano, T.14
-
65
-
-
34547125964
-
Abrogation of signal transducer and activator of transcription 3 reactivation after Src kinase inhibition results in synergistic antitumor effects
-
Johnson, F.M.; Saigal, B.; Tran, H.; Donato, N.J. Abrogation of signal transducer and activator of transcription 3 reactivation after Src kinase inhibition results in synergistic antitumor effects. Clin. Cancer Res., 2007, 13 (14), 4233-4244.
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.14
, pp. 4233-4244
-
-
Johnson, F.M.1
Saigal, B.2
Tran, H.3
Donato, N.J.4
-
66
-
-
0036359548
-
Hypoxia-A key regulatory factor in tumour growth
-
Harris, A.L. Hypoxia-A key regulatory factor in tumour growth. Nat. Rev. Cancer, 2002, 2 (1) 38-47.
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.1
, pp. 38-47
-
-
Harris, A.L.1
-
67
-
-
2942590732
-
Exploiting tumour hypoxia in cancer treatment
-
Brown, J.M.; Wilson, W.R. Exploiting tumour hypoxia in cancer treatment. Nat. Rev. Cancer, 2004, 4 (6), 437-447.
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.6
, pp. 437-447
-
-
Brown, J.M.1
Wilson, W.R.2
-
68
-
-
0141869070
-
Investigating hypoxic tumor physiology through gene expression patterns
-
Denko, N.C.; Fontana, L.A.; Hudson, K.M.; Sutphin, P.D.; Raychaudhuri, S.; Altman, R.; Giaccia, A.J. Investigating hypoxic tumor physiology through gene expression patterns. Oncogene, 2003, 22 (37), 5907-5914.
-
(2003)
Oncogene
, vol.22
, Issue.37
, pp. 5907-5914
-
-
Denko, N.C.1
Fontana, L.A.2
Hudson, K.M.3
Sutphin, P.D.4
Raychaudhuri, S.5
Altman, R.6
Giaccia, A.J.7
-
69
-
-
0032033086
-
Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis
-
Semenza, G.L. Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis. J. Lab. Clin. Med., 1998, 131 (3), 207-214.
-
(1998)
J. Lab. Clin. Med
, vol.131
, Issue.3
, pp. 207-214
-
-
Semenza, G.L.1
-
70
-
-
0031985127
-
Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src
-
Ellis, L.M.; Staley, C.A.; Liu, W.; Fleming, R.Y.; Parikh, N.U.; Bucana, C.D.; Gallick, G.E. Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src. J. Biol. Chem., 1998, 273 (2), 1052-1057.
-
(1998)
J. Biol. Chem
, vol.273
, Issue.2
, pp. 1052-1057
-
-
Ellis, L.M.1
Staley, C.A.2
Liu, W.3
Fleming, R.Y.4
Parikh, N.U.5
Bucana, C.D.6
Gallick, G.E.7
-
71
-
-
18844444774
-
HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
-
Gray, M.J.; Zhang, J.; Ellis, L.M.; Semenza, G.L.; Evans, D.B.; Watowich, S.S.; Gallick, G.E. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene, 2005, 24 (19), 3110-3120.
-
(2005)
Oncogene
, vol.24
, Issue.19
, pp. 3110-3120
-
-
Gray, M.J.1
Zhang, J.2
Ellis, L.M.3
Semenza, G.L.4
Evans, D.B.5
Watowich, S.S.6
Gallick, G.E.7
-
72
-
-
36849093543
-
A redox-silent analogue of tocotrienol inhibits hypoxic adaptation of lung cancer cells
-
Kashiwagi, K.; Harada, K.; Yano, Y.; Kumadaki, I.; Hagiwara, K.; Takebayashi, J.; Kido, W.; Virgona, N.; Yano, T. A redox-silent analogue of tocotrienol inhibits hypoxic adaptation of lung cancer cells. Biochem. Biophys. Res. Commun., 2008, 365 (4), 875-881.
-
(2008)
Biochem. Biophys. Res. Commun
, vol.365
, Issue.4
, pp. 875-881
-
-
Kashiwagi, K.1
Harada, K.2
Yano, Y.3
Kumadaki, I.4
Hagiwara, K.5
Takebayashi, J.6
Kido, W.7
Virgona, N.8
Yano, T.9
-
73
-
-
79955008189
-
Angiogenic signaling aberrantly induced by tumor hypoxia
-
Takenaga, K. Angiogenic signaling aberrantly induced by tumor hypoxia. Front Biosci., 2011, 16, 31-48.
-
(2011)
Front Biosci
, vol.16
, pp. 31-48
-
-
Takenaga, K.1
-
74
-
-
33645241296
-
Connexin 32 down-regulates the fibrinolytic factors in metastatic renal cell carcinoma cells
-
Hagiwara, H.; Sato, H.; Shirai, S.; Kobayashi, S.; Fukumoto K.; Ishida, T.; Seki, T.; Ariga, T.; Yano, T. Connexin 32 down-regulates the fibrinolytic factors in metastatic renal cell carcinoma cells. Life Sci., 2006, 78 (19), 2249-2254.
-
(2006)
Life Sci
, vol.78
, Issue.19
, pp. 2249-2254
-
-
Hagiwara, H.1
Sato, H.2
Shirai, S.3
Kobayashi, S.4
Fukumoto, K.5
Ishida, T.6
Seki, T.7
Ariga, T.8
Yano, T.9
-
75
-
-
0035874951
-
The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics
-
Kozin, S.V.; Shkarin, P.; Gerweck, L.E. The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics. Cancer Res., 2001, 61 (12), 4740-4743.
-
(2001)
Cancer Res
, vol.61
, Issue.12
, pp. 4740-4743
-
-
Kozin, S.V.1
Shkarin, P.2
Gerweck, L.E.3
|