The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics

Cancer Research

Volumn 61, Issue 12, 2001, Pages 4740-4743

  Kozin, Sergey V ^a   Shkarin, Pavel ^b   Gerweck, Leo E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; GLUCOSE;

ACIDIFICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER THERAPY; CELL PH; CYTOTOXICITY; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; HYPOXIC CELL; IONIZING RADIATION; MEMBRANE PERMEABILITY; MOUSE; NONHUMAN; NUDE MOUSE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOSENSITIVITY;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CARCINOMA, SMALL CELL; CELL MEMBRANE; CHLORAMBUCIL; DRUG SYNERGISM; EXTRACELLULAR SPACE; GLUCOSE; HUMANS; HYDROGEN-ION CONCENTRATION; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0035874951     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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