Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas

Neuron

Volumn 33, Issue 6, 2002, Pages 905-919

  Mansvelder, Huibert D ^a   Keath, J Russel ^a   McGehee, Daniel S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; CHOLINERGIC RECEPTOR; DOPAMINE; NICOTINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; GABAERGIC SYSTEM; NERVE CELL EXCITABILITY; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR INTRINSIC ACTIVITY; REWARD; SYNAPTIC TRANSMISSION;

EID: 0037075602     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(02)00625-6     Document Type: Article

References (68)

1. Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes
2. Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist
3. Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices
4. Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices
5. Nicotinic receptor activation in human cerebral cortical interneurons: A mechanism for inhibition and disinhibition of neuronal networks
6. Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus
7. Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats
8. Properties and plasticity of excitatory synapses on dopaminergic and GABAergic cells in the ventral tegmental area
9. Methamidophos: An anticholinesterase without significant effects on postsynaptic receptors or transmitter release
10. Nicotinic acetylcholine subunit mRNA expression in dopaminergic neurons of the rat substantia nigra and ventral tegmental area
11. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area
12. Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors
13. Dopamine and nicotinic receptor binding and the levels of dopamine and homovanillic acid in human brain related to tobacco use
14. Variations in desensitization of nicotinic acetylcholine receptors from hippocampus and midbrain dopamine areas
15. A antagonist bicuculline into the ventral tegmental area in mice: Dependence on D2 dopaminergic mechanisms
16. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
17. Initial symptoms of nicotine dependence in adolescents
18. Present views on the mode of action of acetylcholine in the central nervous system
19. Influence of subunit composition on desensitization of neuronal acetylcholine receptors at low concentrations of nicotine
20. Cholinergic inhibition of ventral midbrain dopamine neurons
21. Nicotine modifies the activity of ventral tegmental area dopaminergic neurons and hippocampal GABAergic neurons
22. Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells
23. Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons
24. Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter
25. Hippocampal synaptic transmission enhanced by low concentrations of nicotine
26. Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine
27. Nicotine induces long-lasting potentiation in the dentate gyrus of nicotine-primed rats
28. Synaptic transmission at nicotinic acetylcholine receptors in rat hippocampal organotypic cultures and slices
29. Higher levels of nicotine in arterial than in venous blood after cigarette smoking
30. Muscarinic activation of ionic currents measured by a new whole-cell recording method
31. Self-infusion of GABA(A) antagonists directly into the ventral tegmental area and adjacent regions
32. GABA(A) receptor blockade in the anterior ventral tegmental area increases extracellular levels of dopamine in the nucleus accumbens of rats
33. Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats
34. Inhibition and disinhibition of pyramidal neurons by activation of nicotinic receptors on hippocampal interneurons
35. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity
36. Two types of neurons in the rat ventral tegmental area and their synaptic inputs
37. Functional nicotinic ACh receptors on interneurones in the rat hippocampus
38. Nicotinic receptors in the brain: Correlating physiology with function
39. GABA and enkephalin projection from the nucleus accumbens and ventral pallidum to the ventral tegmental area
40. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei
41. Drugs of abuse: Anatomy, pharmacology and function of reward pathways
42. 2+ ions in nicotinic facilitation of GABA release in mouse thalamus
43. Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus
44. 3H]gamma-aminobutyric acid release from mouse brain synaptosomes is produced by subactivating concentrations of agonists
45. Nicotine receptors in the mammalian brain
46. Long-term potentiation of excitatory inputs to brain reward areas by nicotine
47. Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons
48. Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors
49. Nicotinic receptor activation excites distinct subtypes of interneurons in the rat hippocampus
50. h in rat midbrain dopaminergic neurons
51. Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area
52. Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area
53. Tobacco - The growing epidemic
54. Mortality from tobacco in developed countries: Indirect estimation from national vital statistics
55. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine
56. Nicotine activates and desensitizes midbrain dopamine neurons
57. Nicotinic modulation of glutamate and GABA synaptic transmission of hippocampal neurons
58. Low access resistance perforated patch recordings using amphotericin B
59. N-methyl-D-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens
60. Nicotine and food induced dopamine release in the nucleus accumbens of the rat: Putative role of alpha7 nicotinic receptors in the ventral tegmental area
61. Molecular cloning, functional properties, and distribution of rat brain alpha 7: A nicotinic cation channel highly permeable to calcium
62. Electrophysiological characterization of GABAergic neurons in the ventral tegmental area
63. A single exposure to amphetamine is sufficient to induce long-term behavioral, neuroendocrine, and neurochemical sensitization in rats
64. Biochemical evidence for gamma-aminobutyrate containing fibres from the nucleus accumbens to the substantia nigra and ventral tegmental area in the rat
65. The pharmacology of mesolimbic dopamine neurons: A dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain
66. Chapter 5, Combating the Tobacco Epidemic
67. A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: An in vitro electrophysiological study