Skin basement membrane: The foundation of epidermal integrity - BM functions and diverse roles of bridging molecules nidogen and perlecan

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Breitkreutz, Dirk ^a,b   Koxholt, Isabell ^a   Thiemann, Kathrin ^a   Nischt, Roswitha ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN FIBER; COLLAGEN TYPE 4; ENTACTIN; KERATIN; LAMININ; NIDOGEN 1; NIDOGEN 2; PERLECAN; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; PROTEOGLYCAN; PROTEOHEPARAN SULFATE;

ARTICLE; ARTIFICIAL SKIN; BASEMENT MEMBRANE; BIRTH; CATALYST; CHEMICAL COMPOSITION; COCULTURE; CONNECTIVE TISSUE DISEASE; DEVELOPMENTAL STAGE; EXPERIMENTAL MOUSE; EXTRACELLULAR MATRIX; GENE TARGETING; HEMIDESMOSOME; HUMAN; LETHALITY; MICROVASCULATURE; MOLECULAR DYNAMICS; NONHUMAN; ORGANOGENESIS; PROTEIN POLYMERIZATION; SKIN; SKIN DEFECT; TISSUE REGENERATION; XENOGRAFT; CHEMISTRY; EPIDERMIS; GROWTH, DEVELOPMENT AND AGING; REVIEW;

BASEMENT MEMBRANE; COLLAGEN TYPE IV; EPIDERMIS; EXTRACELLULAR MATRIX; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; LAMININ; MEMBRANE GLYCOPROTEINS; PROTEOGLYCANS; SKIN;

EID: 84876521580     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/179784     Document Type: Article

References (236)

1. Fuchs E., Raghavan S., Getting under the skin of epidermal morphogenesis. Nature Reviews Genetics 2002 3 3 199 209 10.1038/nrg758 (Pubitemid 34506588)
2. Simpson C. L., Patel D. M., Green K. J., Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis. Nature Reviews Molecular Cell Biology 2011 12 9 565 580 10.1038/nrm3175
3. Tunggal J. A., Helfrich I., Schmitz A., Schwarz H., Günzel D., Fromm M., Kemler R., Krieg T., Niessen C. M., E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. The EMBO Journal 2005 24 6 1146 1156 2-s2.0-17144431742 10.1038/sj.emboj.7600605 (Pubitemid 40516598)
4. Niessen C. M., Tight junctions/adherens junctions: basic structure and function. Journal of Investigative Dermatology 2007 127 11 2525 2532 2-s2.0-35348841509 10.1038/sj.jid.5700865 (Pubitemid 47585053)
5. Hohl D., Lichti U., Breitkreutz D., Steinert P. M., Roop D. R., Transcription of the human loricrin gene in vitro is induced by calcium and cell density and suppressed by retinoic acid. Journal of Investigative Dermatology 1991 96 4 414 418 2-s2.0-0025726921
6. Kalinin A. E., Kajava A. V., Steinert P. M., Epithelial barrier function: assembly and structural features of the cornified cell envelope. BioEssays 2002 24 9 789 800 2-s2.0-0036715005 10.1002/bies.10144 (Pubitemid 35022184)
7. Eckert R. L., Sturniolo M. T., Broome A. M., Ruse M., Rorke E. A., Transglutaminase function in epidermis. Journal of Investigative Dermatology 2005 124 3 481 492 2-s2.0-15044354969 10.1111/j.0022-202X.2005.23627.x (Pubitemid 40381569)
8. Huber M., Siegenthaler G., Mirancea N., Marenholz I., Nizetic D., Breitkreutz D., Mischke D., Hohl D., Isolation and characterization of human repetin, a member of the fused gene family of the epidermal differentiation complex. Journal of Investigative Dermatology 2005 124 5 998 1007 2-s2.0-18244401894 10.1111/j.0022-202X.2005.23675.x (Pubitemid 40629102)
9. Sevilla L. M., Nachat R., Groot K. R., Klement J. F., Uitto J., Djian P., Määttä A., Watt F. M., Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier. Journal of Cell Biology 2007 179 7 1599 1612 2-s2.0-38049014451 10.1083/jcb.200706187
10. Green K. J., Getsios S., Troyanovsky S., Godsel L. M., Intercellular junction assembly, dynamics, and homeostasis. Cold Spring Harbor Perspectives in Biology 2010 2 2 a000125 2-s2.0-77956660919 10.1101/cshperspect.a000125
11. Krieg T., Aumailley M., The extracellular matrix of the dermis: flexible structures with dynamic functions. Experimental Dermatology 2011 20 8 689 695 10.1111/j.1600-0625.2011.01313.x
12. McMillan J. R., Akiyama M., Shimizu H., Epidermal basement membrane zone components: ultrastructural distribution and molecular interactions. Journal of Dermatological Science 2003 31 3 169 177 2-s2.0-0037406396 10.1016/S0923- 1811(03)00045-8 (Pubitemid 36513517)
13. McMillan J. R., Akiyama M., Nakamura H., Shimizu H., Colocalization of multiple laminin isoforms predominantly beneath hemidesmosomes in the upper lamina densa of the epidermal basement membrane. Journal of Histochemistry and Cytochemistry 2006 54 1 109 118 2-s2.0-30044434259 10.1369/jhc.5A6701.2005 (Pubitemid 43049420)
14. Yurchenco P. D., Amenta P. S., Patton B. L., Basement membrane assembly, stability and activities observed through a developmental lens. Matrix Biology 2004 22 7 521 538 2-s2.0-1442310569 10.1016/j.matbio.2003.10.006 (Pubitemid 38283776)
15. Yurchenco P. D., Wadsworth W. G., Assembly and tissue functions of early embryonic laminins and netrins. Current Opinion in Cell Biology 2004 16 5 572 579 2-s2.0-4444285946 10.1016/j.ceb.2004.07.013 (Pubitemid 39201243)
16. LeBleu V. S., MacDonald B., Kalluri R., Structure and function of basement membranes. Experimental Biology and Medicine 2007 232 9 1121 1129 2-s2.0-34848889281 10.3181/0703-MR-72 (Pubitemid 47503053)
17. Mokkapati S., Baranowsky A., Mirancea N., Smyth N., Breitkreutz D., Nischt R., Basement membranes in skin are differently affected by lack of nidogen 1 and 2. Journal of Investigative Dermatology 2008 128 9 2259 2267 2-s2.0-49549122079 10.1038/jid.2008.65
18. Breitkreutz D., Mirancea N., Nischt R., Basement membranes in skin: unique matrix structures with diverse functions? Histochemistry and Cell Biology 2009 132 1 1 10 2-s2.0-67249144694 10.1007/s00418-009-0586-0
19. Yurchenco P. D., Patton B. L., Developmental and pathogenic mechanisms of basement membrane assembly. Current Pharmaceutical Design 2009 15 12 1277 1294 2-s2.0-65649130436 10.2174/138161209787846766
20. McKee K. K., Harrison D., Capizzi S., Yurchenco P. D., Scaffold-forming and adhesive contributions of synthetic laminin-binding proteins to basement membrane assembly. The Journal of Biological Chemistry 2009 284 13 8984 8994 10.1074/jbc.M809719200
21. Rasi K., Hurskainen M., Kallio M., Stavén S., Sormunen R., Heape A. M., Avila R. L., Kirschner D., Muona A., Tolonen U., Tanila H., Huhtala P., Soininen R., Pihlajaniemi T., Lack of collagen XV impairs peripheral nerve maturation and when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction. Journal of Neuroscience 2010 30 43 14490 14501 2-s2.0-78049321312 10.1523/JNEUROSCI.2644-10.2010
22. Tiger C. F., Champliaud M. F., Pedrosa-Domellof F., Thornell L. E., Ekblom P., Gullberg D., Presence of laminin α 5 chain and lack of laminin α 1 chain during human muscle development and in muscular dystrophies. The Journal of Biological Chemistry 1997 272 45 28590 28595 2-s2.0-0030612270 10.1074/jbc.272.45.28590 (Pubitemid 27517812)
23. Carmignac V., Durbeej M., Cell-matrix interactions in muscle disease. Journal of Pathology 2012 226 2 200 218 10.1002/path.3020
24. Kim S. T., Adair-Kirk T. L., Senior R. M., Miner J. H., Functional consequences of cell type-restricted expression of Laminin α 5 in mouse placental labyrinth and kidney glomerular capillaries. PLoS ONE 2012 7 7 e41348 10.1371/journal.pone.0041348
25. Miner J. H., The glomerular basement membrane. Experimental Cell Research 2012 318 9 973 978 10.1016/j.yexcr.2012.02.031
26. Zhang A., Huang S., Progress in pathogenesis of proteinuria. International Journal of Nephrology 2012 2012 14 314251 10.1155/2012/314251
27. Xiao T., Staub W., Robles E., Gosse N. J., Cole G. J., Baier H., Assembly of lamina-specific neuronal connections by slit bound to type IV collagen. Cell 2011 146 1 164 176 2-s2.0-79960006752 10.1016/j.cell.2011.06.016
28. Ackley B. D., Kang S. H., Crew J. R., Suh C., Jin Y., Kramer J. M., The basement membrane components nidogen and type XVIII collagen regulate organization of neuromuscular junctions in Caenorhabditis elegans. Journal of Neuroscience 2003 23 9 3577 3587 2-s2.0-0038545348 (Pubitemid 36958465)
29. Choi Y., Chung H., Jung H., Couchman J. R., Oh E. S., Syndecans as cell surface receptors: unique structure equates with functional diversity. Matrix Biology 2011 30 2 93 99 2-s2.0-79952107602 10.1016/j.matbio.2010.10.006
30. Singhal N., Martin P. T., Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction. Developmental Neurobiology 2011 71 11 982 1005 10.1002/dneu.20953
31. Iozzo R. V., Basement membrane proteoglycans: from cellar to ceiling. Nature Reviews Molecular Cell Biology 2005 6 8 646 656 2-s2.0-23144436642 10.1038/nrm1702 (Pubitemid 41081268)
32. Sher I., Zisman-Rozen S., Eliahu L., Whitelock J. M., Maas-Szabowski N., Yamada Y., Breitkreutz D., Fusenig N. E., Arikawa-Hirasawa E., Iozzo R. V., Bergman R., Ron D., Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation. The Journal of Biological Chemistry 2006 281 8 5178 5187 2-s2.0-33646181651 10.1074/jbc.M509500200 (Pubitemid 43847783)
33. Patel V. N., Likar K. M., Zisman-Rozen S., Cowherd S. N., Lassiter K. S., Sher I., Yates E. A., Turnbull J. E., Ron D., Hoffman M. P., Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation. The Journal of Biological Chemistry 2008 283 14 9308 9317 2-s2.0-44049086666 10.1074/jbc.M709995200
34. Zoeller J. J., Whitelock J. M., Iozzo R. V., Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis. Matrix Biology 2009 28 5 284 291 2-s2.0-67649367545 10.1016/j.matbio.2009.04.010
35. Mueller M. M., Fusenig N. E., Friends or foes-bipolar effects of the tumour stroma in cancer. Nature Reviews Cancer 2004 4 11 839 849 10.1038/nrc1477 (Pubitemid 39472951)
36. Wang B., Sun J., Kitamoto S., Yang M., Grubb A., Chapman H. A., Kalluri R., Shi G. P., Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. The Journal of Biological Chemistry 2006 281 9 6020 6029 2-s2.0-33646827205 10.1074/jbc.M509134200 (Pubitemid 43847703)
37. Franz M., Richter P., Geyer C., Hansen T., Acuña L. D., Hyckel P., Böhmer F. D., Kosmehl H., Berndt A., Mesenchymal cells contribute to the synthesis and deposition of the laminin-5 γ 2 chain in the invasive front of oral squamous cell carcinoma. Journal of Molecular Histology 2007 38 3 183 190 2-s2.0-34250873538 10.1007/s10735-007-9086-5 (Pubitemid 46980551)
38. Franz M., Wolheim A., Richter P., Umbreit C., Dahse R., Driemel O., Hyckel P., Virtanen I., Kosmehl H., Berndt A., Stromal laminin chain distribution in normal, hyperplastic and malignant oral mucosa: relation to myofibroblast occurrence and vessel formation. Journal of Oral Pathology and Medicine 2010 39 4 290 298 2-s2.0-77950481720 10.1111/j.1600-0714.2009.00840.x
39. Guess C. M., Quaranta V., Defining the role of laminin-332 in carcinoma. Matrix Biology 2009 28 8 445 455 2-s2.0-70449703290 10.1016/j.matbio.2009.07.008
40. Gritsenko P. G., Ilina O., Friedl P., Interstitial guidance of cancer invasion. Journal of Pathology 2012 226 2 185 199 10.1002/path.3031
41. Ekblom P., Receptors for laminins during epithelial morphogenesis. Current Opinion in Cell Biology 1996 8 5 700 706 2-s2.0-0030272026 10.1016/S0955-0674(96)80112-8 (Pubitemid 26381728)
42. Durbeej M., Henry M. D., Ferletta M., Campbell K. P., Ekblom P., Distribution of dystroglycan in normal adult mouse tissues. Journal of Histochemistry and Cytochemistry 1998 46 4 449 457 2-s2.0-0031920562 (Pubitemid 28158464)
43. Herzog C., Has C., Franzke C. W., Echtermeyer F. G., Schlötzer- Schrehardt U., Kröger S., Gustafsson E., Fässler R., Bruckner-Tuderman L., Dystroglycan in skin and cutaneous cells: β -subunit is from the cell surface. Journal of Investigative Dermatology 2004 122 6 1372 1380 2-s2.0-2942568034 10.1111/j.0022-202X.2004.22605.x (Pubitemid 38757217)
44. Sirour C., Hidalgo M., Bello V., Buisson N., Darribère T., Moreau N., Dystroglycan is involved in skin morphogenesis downstream of the Notch signaling pathway. Molecular Biology of the Cell 2011 22 16 2957 2969 10.1091/mbc.E11-01-0074
45. Ogawa T., Tsubota Y., Hashimoto J., Kariya Y., Miyazaki K., The short arm of laminin γ 2 chain of laminin-5 (laminin-332) binds syndecan-1 and regulates cellular adhesion and migration by suppressing phosphorylation of integrin β 4 chain. Molecular Biology of the Cell 2007 18 5 1621 1633 2-s2.0-34248215134 10.1091/mbc.E06-09-0806 (Pubitemid 46717545)
46. Xian X., Gopal S., Couchman J. R., Syndecans as receptors and organizers of the extracellular matrix. Cell and Tissue Research 2010 339 1 31 46 2-s2.0-72449210453 10.1007/s00441-009-0829-3
47. Carulli S., Beck K., Dayan G., Boulesteix S., Lortat-Jacob H., Rousselle P., Cell surface proteoglycans syndecan-1 and -4 bind overlapping but distinct sites in laminin α 3 LG45 protein domain. The Journal of Biological Chemistry 2012 287 15 12204 12216 10.1074/jbc.M111.300061
48. Konter U., Kellner I., Klein E., Kaufmann R., Mielke V., Sterry W., Adhesion molecular mapping in normal human skin. Archives of Dermatological Research 1989 281 7 454 462 2-s2.0-0024471550 10.1007/BF00510080 (Pubitemid 20014597)
49. Hertle M. D., Adams J. C., Watt F. M., Integrin expression during human epidermal development in vivo and in vitro. Development 1991 112 1 193 206 2-s2.0-0025728732
50. Goldfinger L. E., Hopkinson S. B., Dehart G. W., Collawn S., Couchman J. R., Jones J. C. R., The α 3 laminin subunit, α 6 β 4 and α 3 β 1 integrin coordinately regulate wound healing in cultured epithelial cells and in the skin. Journal of Cell Science 1999 112 16 2615 2629 2-s2.0-0032841440 (Pubitemid 29429785)
51. Watt F. M., Role of integrins in regulating epidermal adhesion, growth and differentiation. The EMBO Journal 2002 21 15 3919 3926 2-s2.0-0036683057 10.1093/emboj/cdf399 (Pubitemid 34857425)
52. Plopper G. E., Domanico S. Z., Cirulli V., Kiosses W. B., Quaranta V., Migration of breast epithelial cells on laminin-5: differential role of integrins in normal and transformed cell types. Breast Cancer Research and Treatment 1998 51 1 57 69 2-s2.0-0031794915 10.1023/A:1006086218174 (Pubitemid 28550160)
53. Pouliot N., Nice E. C., Burgess A. W., Laminin-10 mediates basal and EGF-stimulated motility of human colon carcinoma cells via α 3 β 1 and α 6 β 4 integrins. Experimental Cell Research 2001 266 1 1 10 2-s2.0-0035872237 10.1006/excr.2001.5197 (Pubitemid 32989037)
54. Pouliot N., Kusuma N., Laminin-511: a multi-functional adhesion protein regulating cell migration, tumor invasion and metastasis. Cell Adhesion and Migration 2013 7 1 142 149 10.4161/cam.22125
55. Legate K. R., Fässler R., Mechanisms that regulate adaptor binding to β -integrin cytoplasmic tails. Journal of Cell Science 2009 122 2 187 198 2-s2.0-61449213806 10.1242/jcs.041624
56. Karaköse E., Sciller H. B., Fässler R., The kindlins at a glance. Journal of Cell Science 2010 123 2353 2356 10.1242/jcs.064600
57. Estrach S., Cailleteau L., Franco C. A., Gerhardt H., Stefani C., Lemichez E., Gagnoux-Palacios L., Meneguzzi G., Mettouchi A., Laminin-binding integrins induce DII4 expression and Notch signaling in endothelial cells. Circulation Research 2011 109 172 182 10.1161/CIRCRESAHA.111.240622
58. Qu H., Wen T., Pesch M., Aumailley M., Partial loss of epithelial phenotype in kindling-1-deficient keratinocytes. The American Journal of Pathology 2012 180 4 1581 1592 10.1016/j.ajpath.2012.01.005
59. Wickström S. A., Lange A., Montanez E., Fässler R., The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! The EMBO Journal 2010 29 2 281 291 2-s2.0-75049085759 10.1038/emboj.2009.376
60. Borradori L., Sonnenberg A., Structure and function of hemidesmosomes: more than simple adhesion complexes. Journal of Investigative Dermatology 1999 112 4 411 418 2-s2.0-0032908323 10.1046/j.1523-1747.1999.00546.x (Pubitemid 29171928)
61. Litjens S. H. M., de Pereda J. M., Sonnenberg A., Current insights into the formation and breakdown of hemidesmosomes. Trends in Cell Biology 2006 16 7 376 383 2-s2.0-33745947286 10.1016/j.tcb.2006.05.004 (Pubitemid 44062316)
62. Wilhelmsen K., Litjens S. H. M., Sonnenberg A., Multiple functions of the integrin α 6 β 4 in epidermal homeostasis and tumorigenesis. Molecular and Cellular Biology 2006 26 8 2877 2886 2-s2.0-33645837225 10.1128/MCB.26.8.2877-2886.2006
63. Tennenbaum T., Weiner A. K., Belanger A. J., Glick A. B., Hennings H., Yuspa S. H., The suprabasal expression of α 6 β 4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis. Cancer Research 1993 53 20 4803 4810 2-s2.0-0027491154 (Pubitemid 23326170)
64. Tomakidi P., Mirancea N., Fusenig N. E., Herold-Mende C., Bosch F. X., Breitkreutz D., Defects of basement membrane and hemidesmosome structure correlate with malignant phenotype and stromal interactions in HaCaT-Ras xenografts. Differentiation 1999 64 5 263 275 2-s2.0-0033047394 10.1007/s002580050280 (Pubitemid 29250933)
65. Marinkovich M. P., Tumour microenvironment: laminin 332 in squamous-cell carcinoma. Nature Reviews Cancer 2007 7 5 370 380 2-s2.0-34247474890 10.1038/nrc2089 (Pubitemid 46652480)
66. Li A., Pouliot N., Redvers R., Kaur P., Extensive tissue-regenerative capacity of neonatal human keratinocyte stem cells and their progeny. Journal of Clinical Investigation 2004 113 3 390 400 2-s2.0-1542347759 10.1172/JCI200419140 (Pubitemid 38544183)
67. Domogatskaya A., Rodin S., Boutaud A., Tryggvason K., Laminin-511 but not -332, -111, or -411 enables mouse embryonic stem cell self-renewal in vitro. Stem Cells 2008 26 11 2800 2809 2-s2.0-56249121926 10.1634/stemcells.2007-0389
68. Fuchs E., Finding one's niche in the skin. Cell Stem Cell 2009 4 6 499 502 2-s2.0-66049129451 10.1016/j.stem.2009.05.001
69. Connelly J. T., Mishra A., Gautrot J. E., Watt F. M., Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation. PLoS ONE 2011 6 11 e27259 10.1371/journal. pone.0027259
70. Fujiwara H., Ferreira M., Donati G., Marciano D. K., Linton J. M., Sato Y., Hartner A., Sekiguchi K., Reichardt L. F., Watt F. M., The basement membrane of hair follicle stem cells is a muscle cell niche. Cell 2011 144 4 577 589 2-s2.0-79951716389 10.1016/j.cell.2011.01.014
71. Boehnke K., Falkowska-Hansen B., Stark H.-J., Boukamp P., Stem cells of the human epidermis and their niche: composition and function in epidermal regeneration and carcinogenesis. Carcinogenesis 2012 33 7 1247 1258 10.1093/carcin/bgs136
72. Trappmann B., Gautrot J. E., Connelly J. T., Strange D. G. T., Li Y., Oyen M. L., Cohen Stuart M. A., Boehm H., Li B., Vogel V., Spatz J. P., Watt F. M., Huck W. T. S., Extracellular-matrix tethering regulates stem-cell fate. Nature Materials 2012 11 7 642 649 10.1038/nmat3339
73. Timpl R., Brown J. C., Supramolecular assembly of basement membranes. BioEssays 1996 18 2 123 132 2-s2.0-0030087944
74. Yurchenco P. D., Cheng Y. S., Ruben G. C., Self-assembly of a high molecular weight basement membrane heparan sulfate proteoglycan into dimers and oligomers. The Journal of Biological Chemistry 1987 262 36 17668 17676 2-s2.0-0023630089 (Pubitemid 18032253)
75. Kruegel J., Miosge N., Basement membrane components are key players in specialized extracellular matrices. Cellular and Molecular Life Sciences 2010 67 17 2879 2895 2-s2.0-77956755675 10.1007/s00018-010-0367-x
76. Hohenester E., Yurchenco P. D., Laminins in basement membrane assembly. Cell Adhesion and Migration 2013 7 1 56 63 10.4161/cam.21831
77. Aumailley M., Rousselle P., Laminins of the dermo-epidermal junction. Matrix Biology 1999 18 1 19 28 2-s2.0-0032910126 10.1016/S0945-053X(98)00004-3 (Pubitemid 29213824)
78. Miner J. H., Yurchenco P. D., Laminin functions in tissue morphogenesis. Annual Review of Cell and Developmental Biology 2004 20 255 284 2-s2.0-8444247525 10.1146/annurev.cellbio.20.010403.094555 (Pubitemid 39488639)
79. Aumailley M., Bruckner-Tuderman L., Carter W. G., Deutzmann R., Edgar D., Ekblom P., Engel J., Engvall E., Hohenester E., Jones J. C. R., Kleinman H. K., Marinkovich M. P., Martin G. R., Mayer U., Meneguzzi G., Miner J. H., Miyazaki K., Patarroyo M., Paulsson M., Quaranta V., Sanes J. R., Sasaki T., Sekiguchi K., Sorokin L. M., Talts J. F., Tryggvason K., Uitto J., Virtanen I., von der Mark K., Wewer U. M., Yamada Y., Yurchenco P. D., A simplified laminin nomenclature. Matrix Biology 2005 24 5 326 332 2-s2.0-22544480570 10.1016/j.matbio.2005.05.006 (Pubitemid 41021635)
80. Yousif L. F., Di Russo J., Sorokin L., Laminin isoforms in endothelial and perivascular basement membranes. Cell Adhesion and Migration 2013 7 1 101 110 10.4161/cam.22680
81. Yurchenco P. D., Cheng Y. S., Colognato H., Laminin forms an independent network in basement membranes. Journal of Cell Biology 1992 117 5 1119 1133 2-s2.0-0026639532 10.1083/jcb.117.5.1119
82. Timpl R., Dziadek M., Fujiwara S., Nowack H., Wick G., Nidogen: a new, self-aggregating basement membrane protein. European Journal of Biochemistry 1983 137 3 455 465 2-s2.0-0021105533
83. 2+ binding in the self-aggregation of laminin-nidogen complexes. The Journal of Biological Chemistry 1988 263 11 5425 5430 2-s2.0-0023818513
84. Behrens D. T., Villone D., Koch M., Brunner G., Sorokin L., Robenek H., Bruckner-Tuderman L., Bruckner P., Hansen U., The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens. The Journal of Biological Chemistry 2012 287 22 18700 18709 10.1074/jbc.M111.336073
85. Dzamba B. J., Keene D. R., Isogai Z., Charbonneau N. L., Karaman-Jurukovska N., Simon M., Sakai L. Y., Assembly of epithelial cell fibrillins. Journal of Investigative Dermatology 2001 117 6 1612 1620 2-s2.0-0035674151 10.1046/j.0022-202x.2001.01588.x (Pubitemid 34032795)
86. Tiedemann K., Sasaki T., Gustafsson E., Göhring W., Bätge B., Notbohm H., Timpl R., Wedel T., Schlötzer-Schrehardt U., Reinhardt D. P., Microfibrils at basement membrane zones interact with perlecan via fibrillin-1. The Journal of Biological Chemistry 2005 280 12 11404 11412 2-s2.0-20144365647 10.1074/jbc.M409882200 (Pubitemid 40418449)
87. Bonod-Bidaud C., Roulet M., Hansen U., Elsheikh A., Malbouyres M., Ricard-Blum S., Faye C., Vaganay E., Rousselle P., Ruggiero F., In vivo evidence for a bridging role of a collagen V subtype at the epidermis-dermis interface. Journal of Investigative Dermatology 2012 132 7 1841 1849 10.1038/jid.2012.56
88. Miosge N., Simniok T., Sprysch P., Herken R., The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo. Journal of Histochemistry and Cytochemistry 2003 51 3 285 296 2-s2.0-0037369808 (Pubitemid 36245984)
89. Sercu S., Zhang M., Oyama N., Hansen U., Ghalbzouri A. E. L., Jun G., Geentjens K., Zhang L., Merregaert J. H., Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM1 is a basement membrane protein of the skin. Journal of Investigative Dermatology 2008 128 6 1397 1408 2-s2.0-43749087834 10.1038/sj.jid.5701231 (Pubitemid 351693212)
90. Merregaert J., van Langen J., Hansen U., Ponsaerts P., El Ghalbzouri A., Steenackers E., van Ostade X., Sercu S., Phospholipid scramblase 1 is secreted by a lipid raft-dependent pathway and interacts with the extracellular matrix protein 1 in the dermal epidermal junction zone of human skin. The Journal of Biological Chemistry 2010 285 48 37823 37837 2-s2.0-78549242695 10.1074/jbc.M110.136408
91. Yurchenco P. D., Cheng Y. S., Self-assembly and calcium-binding sites in laminin, a three-arm interaction model. The Journal of Biological Chemistry 1993 268 23 17286 17299 (Pubitemid 23236966)
92. Garbe J. H. O., Göhring W., Mann K., Timpl R., Sasaki T., Complete sequence, analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin α 3B and α 5 chains. Biochemical Journal 2002 362 1 213 221 2-s2.0-0037085315 10.1042/0264-6021:3620213 (Pubitemid 34174478)
93. McKee K. K., Harrison D., Capizzi S., Yurchenco P. D., Role of laminin terminal globular domains in basement membrane assembly. The Journal of Biological Chemistry 2007 282 29 21437 21447 2-s2.0-34547093441 10.1074/jbc.M702963200 (Pubitemid 47099937)
94. Miner J. H., Laminins and their role in development. Microscopy Research and Technique 2008 71 5 349 356 10.1002/jemt.20563 (Pubitemid 351620857)
95. Yurchenco P. D., Ruben G. C., Basement membrane structure in situ: evidence for lateral associations in the type IV collagen network. Journal of Cell Biology 1987 105 6 I 2559 2568 2-s2.0-0023600043 (Pubitemid 18017686)
96. Pöschl E., Schlötzer-Schrehardt U., Brachvogel B., Saito K., Ninomiya Y., Mayer U., Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development. Development 2004 131 7 1619 1628 10.1242/dev.01037 (Pubitemid 38559288)
97. Smyth N., Vatansever S. H., Murray P., Meyer M., Frie C., Paulsson M., Edgar D., Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation. Journal of Cell Biology 1999 144 1 151 160 2-s2.0-0033545239 10.1083/jcb.144.1.151 (Pubitemid 29047018)
98. Miner J. H., Li C., Mudd J. L., Go G., Sutherland A. E., Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation. Development 2004 131 10 2247 2256 2-s2.0-3042790010 10.1242/dev.01112 (Pubitemid 38877634)
99. Fox J. W., Mayer U., Nischt R., Aumailley M., Reinhardt D., Wiedemann H., Mann K., Timpl R., Krieg T., Engel J., Chu M. L., Recombinant nidogen consists of three globular domains and mediates binding of laminin to collagen type IV. The EMBO Journal 1991 10 11 3137 3146 2-s2.0-0026006388 (Pubitemid 21905336)
100. Battaglia C., Mayer U., Aumailley M., Timpl R., Basement-membrane heparan sulfate proteoglycan binds to laminin by its heparan sulfate chains and to nidogen by sites in the protein core. European Journal of Biochemistry 1992 208 2 359 366 2-s2.0-0026703151
101. Aumailley M., Battaglia C., Mayer U., Reinhardt D., Nischt R., Timpl R., Fox J. W., Nidogen mediates the formation of ternary complexes of basement membrane components. Kidney International 1993 43 1 7 12 2-s2.0-0027263329 (Pubitemid 23167438)
102. Ettner N., Göhring W., Sasaki T., Mann K., Timpl R., The N-terminal globular domain of the laminin α 1 chain binds to α 1 β 1 and α 2 β 1 integrins and to the heparan sulfate-containing domains of perlecan. The FEBS Letters 1998 430 3 217 221 2-s2.0-0032479214 10.1016/S0014-5793(98)00601-2 (Pubitemid 28337916)
103. Bechtel M., Keller M. V., Bloch W., Sasaki T., Boukamp P., Zaucke F., Paulsson M., Nischt R., Different domains in nidogen-1 and nicdogen-2 drive basement membrane formation in skin organotypic cocultures. The FASEB Journal 2012 26 9 3637 3648 10.1096/fj.11-194597
104. Arikawa-Hirasawa E., Watanabe H., Takami H., Hassell J. R., Yamada Y., Perlecan is essential for cartilage and cephalic development. Nature Genetics 1999 23 3 354 358 2-s2.0-0032726952 10.1038/15537 (Pubitemid 29526437)
105. Costell M., Gustafsson E., Aszódi A., Mörgelin M., Bloch W., Hunziker E., Addicks K., Timpl R., Fässler R., Perlecan maintains the integrity of cartilage and some basement membranes. Journal of Cell Biology 1999 147 5 1109 1122 2-s2.0-0033615959 10.1083/jcb.147.5.1109
106. Bader B. L., Smyth N., Nedbal S., Miosge N., Baranowsky A., Mokkapati S., Murshed M., Nischt R., Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice. Molecular and Cellular Biology 2005 25 15 6846 6856 2-s2.0-22544456862 10.1128/MCB.25.15.6846- 6856.2005 (Pubitemid 41023254)
107. Carlin B., Jaffe R., Bender B., Chung A. E., Entactin, a novel basal lamina-associated sulfated glycoprotein. The Journal of Biological Chemistry 1981 256 10 5208 5214 2-s2.0-0019888064 (Pubitemid 11057899)
108. Kimura N., Toyoshima T., Kojima T., Shimane M., Entactin-2: a new member of basement membrane protein with high homology to entactin/nidogen. Experimental Cell Research 1998 241 1 36 45 2-s2.0-0031820133 10.1006/excr.1998.4016 (Pubitemid 28366577)
109. Kohfeldt E., Sasaki T., Göhring W., Timpl R., Nidogen-2: a new basement membrane protein with diverse binding properties. Journal of Molecular Biology 1998 282 1 99 109 2-s2.0-0032508461 10.1006/jmbi.1998.2004 (Pubitemid 28418662)
110. Salmivirta K., Talts J. F., Olsson M., Sasaki T., Timpl R., Ekblom P., Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens. Experimental Cell Research 2002 279 2 188 201 2-s2.0-0036405396 10.1006/excr.2002.5611 (Pubitemid 35217548)
111. Ho M. S. P., Böse K., Mokkapati S., Nischt R., Smyth N., Nidogens-extracellular matrix linker molecules. Microscopy Research and Technique 2008 71 5 387 395 2-s2.0-42949163951 10.1002/jemt.20567 (Pubitemid 351620861)
112. Pöschl E., Fox J. W., Block D., Mayer U., Timpl R., Two non-contiguous regions contribute to nidogen binding to a single EGF-like motif of the laminin γ 1 chain. The EMBO Journal 1994 13 16 3741 3747 2-s2.0-0028074247
113. Kadoya Y., Salmivirta K., Talts J. F., Kadoya K., Mayer U., Timpl R., Ekblom P., Importance of nidogen binding to laminin γ 1 for branching epithelial morphogenesis of the submandibular gland. Development 1997 124 3 683 691 2-s2.0-0031059074 (Pubitemid 27092434)
114. Gersdorff N., Kohfeldt E., Sasaki T., Timpl R., Miosge N., Laminin γ 3 chain binds to nidogen and is located in murine basement membranes. The Journal of Biological Chemistry 2005 280 23 22146 22153 2-s2.0-20444493196 10.1074/jbc.M501875200 (Pubitemid 40827870)
115. Mokkapati S., Fleger-Weckmann A., Bechtel M., Koch M., Breitkreutz D., Mayer U., Smyth N., Nischt R., Basement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin γ 1 chain. The Journal of Biological Chemistry 2011 286 3 1911 1918 2-s2.0-78751477107 10.1074/jbc.M110.149864
116. Whitelock J. M., Melrose J., Iozzo R. V., Diverse cell signaling events modulated by perlecan. Biochemistry 2008 47 43 11174 11183 2-s2.0-54849436630 10.1021/bi8013938
117. Mirancea N., Hausser I., Metze D., Stark H. J., Boukamp P., Breitkreutz D., Junctional basement membrane anomalies of skin and mucosa in lipoid proteinosis (hyalinosis cutis et mucosae). Journal of Dermatological Science 2007 45 3 175 185 2-s2.0-33846821974 10.1016/j.jdermsci.2006.11.010 (Pubitemid 46216047)
118. Paquet-Fifield S., Schlüter H., Li A., Aitken T., Gangatirkar P., Blashki D., Koelmeyer R., Pouliot N., Palatsides M., Ellis S., Brouard N., Zannettino A., Saunders N., Thompson N., Li J., Kaur P., A role for pericytes as microenvironmental regulators of human skin tissue regeneration. Journal of Clinical Investigation 2009 119 9 2795 2806 10.1172/JCI38535
119. Sterk L. M. T., Geuijen C. A. W., Oomen L. C. J. M., Calafat J., Janssen H., Sonnenberg A., The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin α 6 β 4 and may regulate the spatial organization of hemidesmosomes. Journal of Cell Biology 2000 149 4 969 982 2-s2.0-0034658462 10.1083/jcb.149.4.969 (Pubitemid 30327246)
120. Sonnenberg A., Calafat J., Janssen H., Daams H., van der Raaij-Helmer L. M. H., Falconi R., Kennel S. J., Aplin J. D., Baker J., Loizidou M., Garrod D., Integrin α 6/ β 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion. Journal of Cell Biology 1991 113 4 907 917 2-s2.0-0025886308 (Pubitemid 21909724)
121. Sterk L. M. T., Geuijen C. A. W., van den Berg J. G., Claessen N., Weening J. J., Sonnenberg A., Association of the tetraspanin CD151 with the laminin-binding integrins α 3 β 1, α 6 Β 1, α 6 β 4 and α 7 β 1 in cells in culture and in vivo. Journal of Cell Science 2002 115 6 1161 1173 (Pubitemid 34272481)
122. Franzke C. W., Bruckner P., Bruckner-Tuderman L., Collagenous transmembrane proteins: recent insights into biology and pathology. The Journal of Biological Chemistry 2005 280 6 4005 4008 2-s2.0-14244264636 10.1074/jbc.R400034200 (Pubitemid 40288560)
123. Qiao H., Shibaki A., Long H. A., Wang G., Li Q., Nishie W., Abe R., Akiyama M., Shimizu H., McMillan J. R., Collagen XVII participates in keratinocyte adhesion to collagen IV, and in p38MAPK-dependent migration and cell signaling. Journal of Investigative Dermatology 2009 129 9 2288 2295 2-s2.0-70349737907 10.1038/jid.2009.20
124. Nishie W., Kiritsi D., Nyström A., Hofmann S. C., Bruckner-Tuderman L., Dynamic interactions of epidermal collagen XVII with extracellular matrix. The American Journal of Pathology 2011 179 2 829 837 10.1016/j.ajpath.2011.04. 019
125. Sugawara K., Tsuruta D., Ishii M., Jones J. C. R., Kobayashi H., Laminin-332 and -511 in skin. Experimental Dermatology 2008 17 6 473 480 2-s2.0-43449120176 10.1111/j.1600-0625.2008.00721.x (Pubitemid 351663274)
126. Goldfinger L. E., Stack M. S., Jones J. C. R., Processing of laminin-5 and its functional consequences: role of plasmin and tissue-type plasminogen activator. Journal of Cell Biology 1998 141 1 255 265 2-s2.0-0032489876 10.1083/jcb.141.1.255 (Pubitemid 28182656)
127. Amano S., Scott I. C., Takahara K., Koch M., Champliaud M. F., Gerecke D. R., Keene D. R., Hudson D. L., Nishiyama T., Lee S., Greenspan D. S., Burgeson R. E., Bone morphogenetic protein 1 is an extracellular processing enzyme of the laminin 5 γ 2 chain. The Journal of Biological Chemistry 2000 275 30 22728 22735 2-s2.0-0034725611 10.1074/jbc.M002345200 (Pubitemid 30646154)
128. Hormia M., Falk-Marzillier J., Plopper G., Tamura R. N., Jones J. C. R., Quaranta V., Rapid spreading and mature hemidesmosome formation in HaCaT keratinocytes induced by incubation with soluble laminin-5r. Journal of Investigative Dermatology 1995 105 4 557 561 2-s2.0-0028844123
129. Plopper G., Falk-Marzillier J., Glaser S., Fitchmun M., Giannelli G., Romano T., Jones J. C. R., Quaranta V., Changes in expression of monoclonal antibody epitopes on laminin-5r induced by cell contact. Journal of Cell Science
130. Hintermann E., Quaranta V., Epithelial cell motility on laminin-5: regulation by matrix assembly, proteolysis, integrins and erbB receptors. Matrix Biology 2004 23 2 75 85 2-s2.0-3042749811 10.1016/j.matbio.2004.03.001 (Pubitemid 38891522)
131. Schneider H., Mühle C., Pacho F., Biological function of laminin-5 and pathogenic impact of its deficiency. European Journal of Cell Biology 2007 86 11-12 701 717 2-s2.0-36048939748 10.1016/j.ejcb.2006.07.004 (Pubitemid 350082193)
132. Tripathi M., Nandana S., Yamashita H., Ganesan R., Kirchhofer D., Quaranta V., Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression. The Journal of Biological Chemistry 2008 283 45 30576 30584 2-s2.0-57649155897 10.1074/jbc.M802312200
133. Ozawa T., Tsuruta D., Jones J. C. R., Ishii M., Ikeda K., Harada T., Aoyama Y., Kawada A., Kobayashi H., Dynamic relationship of focal contacts and hemidesmosome protein complexes in live cells. Journal of Investigative Dermatology 2010 130 6 1624 1635 2-s2.0-77952426752 10.1038/jid.2009.439
134. Winterwood N. E., Varzavand A., Meland M. N., Ashman L. K., Stipp C. S., A critical role for tetraspanin CD151 in α 3 β 1 and α 6 β 4 integrin-dependent tumor cell functions on laminin-5. Molecular Biology of the Cell 2006 17 6 2707 2721 2-s2.0-33744763348 10.1091/mbc.E05-11-1042 (Pubitemid 43825507)
135. Koshikawa N., Minegishi T., Sharabi A., Quaranta V., Seiki M., Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin γ 2 chain. The Journal of Biological Chemistry 2005 280 1 88 93 2-s2.0-12844275940 10.1074/jbc.M411824200 (Pubitemid 40164968)
136. Shen X. M., Wu Y. P., Feng Y. B., Luo M. L., Du X. L., Zhang Y., Cai Y., Xu X., Han Y. L., Zhang X., Zhan Q. M., Wang M. R., Interaction of MT1-MMP and laminin-5 γ 2 chain correlates with metastasis and invasiveness in human esophageal squamous cell carcinoma. Clinical and Experimental Metastasis 2007 24 7 541 550 2-s2.0-34948878106 10.1007/s10585-007-9091-9 (Pubitemid 47524812)
137. Veitch D. P., Nokelainen P., McGowan K. A., Mammalian tolloid metalloproteinase, and not matrix metalloproteinase 2 or membrane type 1 metalloproteinase, processes laminin-5 in keratinocytes and skin. The Journal of Biological Chemistry 2003 278 18 15661 15668 10.1074/jbc.M210588200 (Pubitemid 36799676)
138. Rousselle P., Keene D. R., Ruggiero F., Champliaud M. F., van Rest M. D., Burgeson R. E., Laminin 5 binds the NC-1 domain of type VII collagen. Journal of Cell Biology 1997 138 3 719 728 2-s2.0-0030855296 10.1083/jcb.138.3.719 (Pubitemid 27349850)
139. Bruckner-Tuderman L., Hereditary skin diseases of anchoring fibrils. Journal of Dermatological Science 1999 20 2 122 133 2-s2.0-0032973323 10.1016/S0923-1811(99)00018-3 (Pubitemid 29251588)
140. Villone D., Fritsch A., Koch M., Bruckner-Tuderman L., Hansen U., Bruckner P., Supramolecular interactions in the dermo-epidermal junction zone: anchoring fibril-collagen VII tightly binds to banded collagen fibrils. The Journal of Biological Chemistry 2008 283 36 24506 24513 2-s2.0-54049117263 10.1074/jbc.M802415200
141. Fritsch A., Spassov S., Elfert S., Schlosser A., Gache Y., Meneguzzi G., Bruckner-Tuderman L., Dominant-negative effects of COL7A1 mutations can be rescued by controlled overexpression of normal collagen VII. The Journal of Biological Chemistry 2009 284 44 30248 30256 2-s2.0-71049190003 10.1074/jbc.M109.045294
142. Aumailley M., Has C., Tunggal L., Bruckner-Tuderman L., Molecular basis of inherited skin-blistering disorders, and therapeutic implications. Expert Reviews in Molecular Medicine 2006 8 24 1 21 2-s2.0-33750212860 10.1017/S1462399406000123 (Pubitemid 44605421)
143. Chaudhari P., Marinkovich M. P., What's new in blistering disorders? Current Allergy and Asthma Reports 2007 7 4 255 263 2-s2.0-34250728970 10.1007/s11882-007-0038-7 (Pubitemid 46958742)
144. Marinkovich M. P., Keene D. R., Rimberg C. S., Burgeson R. E., Cellular origin of the dermal-epidermal basement membrane. Developmental Dynamics 1993 197 4 255 267 2-s2.0-0027454382 (Pubitemid 23321876)
145. Ekblom P., Ekblom M., Fecker L., Klein G., Zhang H. Y., Kadoya Y., Chu M. L., Mayer U., Timpl R., Role of mesenchymal nidogen for epithelial morphogenesis in vitro. Development 1994 120 7 2003 2014 2-s2.0-0028246735 (Pubitemid 24209733)
146. Fleischmajer R., Schechter A., MacDonald E. D., Bruns M., Perlish J. S., Pan T. C., Timpl R., Chu M. L., Skin fibroblasts are the only source of nidogen during early basal lamina formation in vitro. Journal of Investigative Dermatology 1995 105 4 597 601 2-s2.0-0028857022
147. Miner J. H., Patton B. L., Lentz S. I., Gilbert D. J., Snider W. D., Jenkins N. A., Copeland N. G., Sanes J. R., The laminin α chains: expression, developmental transitions, and chromosomal locations of α 1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel α 3 isoform. Journal of Cell Biology 1997 137 3 685 701 2-s2.0-0030919488 10.1083/jcb.137.3.685 (Pubitemid 27200670)
148. Spenlé C., Simon-Assmann P., Orend G., Miner J. H., Laminin α 5 guides tissue patterning and organogenesis. Cell Adhesion and Migration 2013 7 1 90 100 10.4161/cam.22236
149. Nischt R., Schmidt C., Mirancea N., Baranowsky A., Mokkapati S., Smyth N., Woenne E. C., Stark H. J., Boukamp P., Breitkreutz D., Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture. Journal of Investigative Dermatology 2007 127 3 545 554 2-s2.0-33847078062 10.1038/sj.jid.5700562
150. Tani T., Lehto V. P., Virtanen I., Expression of laminins 1 and 10 in carcinoma cells and comparison of their roles in cell adhesion. Experimental Cell Research 1999 248 1 115 121 2-s2.0-0033541393 10.1006/excr.1999.4399 (Pubitemid 29393935)
151. Virtanen I., Gullberg D., Rissanen J., Kivilaakso E., Kiviluoto T., Laitinen L. A., Lehto V. P., Ekblom P., Laminin α 1-chain shows a restricted distribution in epithelial basement membranes of fetal and adult human tissues. Experimental Cell Research 2000 257 2 298 309 2-s2.0-0034658727 10.1006/excr.2000.4883 (Pubitemid 30390481)
152. Murshed M., Smyth N., Miosge N., Karolat J., Krieg T., Paulsson M., Nischt R., The absence of nidogen 1 does not affect murine basement membrane formation. Molecular and Cellular Biology 2000 20 18 7007 7012 2-s2.0-0033821010 10.1128/MCB.20.18.7007-7012.2000
153. Schymeinsky J., Nedbal S., Miosge N., Pöschl E., Rao C., Beier D. R., Skarnes W. C., Timpl R., Bader B. L., Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice. Molecular and Cellular Biology 2002 22 19 6820 6830 2-s2.0-0036785584 10.1128/MCB.22.19.6820-6830.2002
154. Miosge N., Sasaki T., Timpl R., Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice. Matrix Biology 2002 21 7 611 621 2-s2.0-0036860601 10.1016/S0945-053X(02)00070-7 (Pubitemid 35435301)
155. Dong L., Chen Y., Lewis M., Hsieh J. C., Reing J., Chaillet J. R., Howell C. Y., Melhem M., Inoue S., Kuszak J. R., DeGeest K., Chung A. E., Neurologic defects and selective disruption of basement membranes in mice lacking entactin-1/nidogen-1. Laboratory Investigation 2002 82 12 1617 1630 2-s2.0-0036903314 (Pubitemid 35462975)
156. Köhling R., Nischt R., Vasudevan A., Ho M., Weiergräber M., Schneider T., Smyth N., Nidogen and nidogen-associated basement membrane proteins and neuronal plasticity. Neurodegenerative Diseases 2006 3 1-2 56 61 2-s2.0-33646806120 10.1159/000092094 (Pubitemid 43760369)
157. Vasudevan A., Ho M. S. P., Weiergräber M., Nischt R., Schneider T., Lie A., Smyth N., Köhling R., Basement membrane protein nidogen-1 shapes hippocampal synaptic plasticity and excitability. Hippocampus 2010 20 5 608 620 2-s2.0-77951594641 10.1002/hipo.20660
158. Willem M., Miosge N., Halfter W., Smyth N., Jannetti I., Burghart E., Timpl R., Mayer U., Specific ablation of the nidogen-binding site in the laminin γ 1 chain interferes with kidney and lung development. Development 2002 129 11 2711 2722 2-s2.0-0036333442 (Pubitemid 34874254)
159. Mirancea N., Hausser I., Beck R., Metze D., Fusenig N. E., Breitkreutz D., Vascular anomalies in lipoid proteinosis (hyalinosis cutis et mucosae): basement membrane components and ultrastructure. Journal of Dermatological Science 2006 42 3 231 239 2-s2.0-33746877537 10.1016/j.jdermsci.2006.01.004
160. Breitkreutz D., Bohnert A., Herzmann E., Bowden P. E., Boukamp P., Fusenig N. E., Differentiation specific functions in cultured and transplanted mouse keratinocytes: environmental influences on ultrastructure and keratin expression. Differentiation 1984 26 2 154 169 2-s2.0-0021267398 (Pubitemid 14100142)
161. Breitkreutz D., Hornung J., Pohlmann J., Brown-Bierman L., Bohnert A., Bowden P. E., Fusenig N. E., Environmental induction of differentiation-specific keratins in malignant mouse keratinocyte lines. European Journal of Cell Biology 1986 42 2 255 267 (Pubitemid 17222761)
162. Boukamp P., Breitkreutz D., Stark H. J., Fusenig N. E., Mesenchyme-mediated and endogenous regulation of growth and differentiation of human skin keratinocytes derived from different body sites. Differentiation 1990 44 2 150 161 2-s2.0-0025083224 10.1111/j.1432-0436.1990.tb00548.x (Pubitemid 20263308)
163. Boukamp P., Dzarlieva-Petrusevska R. T., Breitkreutz D., Hornung J., Markham A., Fusenig N. E., Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. Journal of Cell Biology 1988 106 3 761 771 2-s2.0-0023852747 (Pubitemid 18089976)
164. Ryle C. M., Breitkreutz D., Stark H. J., Leigh I. M., Steinert P. M., Roop D., Fusenig N. E., Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation 1989 40 1 42 54 2-s2.0-0024402762 (Pubitemid 19149292)
165. 2+ Differentiation 1993 54 3 201 217 2-s2.0-0027385999 (Pubitemid 23352264)
166. Breitkreutz D., Boukamp P., Ryle C. M., Stark H. J., Roop D. R., Fusenig N. E., Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumorigenic clones of the human HaCaT cell line. Cancer Research 1991 51 16 4402 4409 2-s2.0-0025942711
167. Limat A., Breitkreutz D., Thiekoetter G., Klein C. E., Braathen L. R., Hunziker T., Fusenig N. E., Formation of a regular neo-epidermis by cultured human outer root sheath cells grafted on nude mice. Transplantation 1995 59 7 1032 1038 2-s2.0-0028918414
168. Limat A., Stockhammer E., Breitkreutz D., Schaffner T., Egelrud T., Salomon D., Fusenig N. E., Braathen L. R., Hunziker T., Endogeneously regulated site-specific differentiation of human palmar skin keratinocytes in organotypic cocultures and in nude mouse transplants. European Journal of Cell Biology 1996 69 3 245 258 2-s2.0-0029981483 (Pubitemid 26095219)
169. Breitkreutz D., Stark H. J., Mirancea N., Tomakidi P., Steinbauer H., Fusenig N. E., Integrin and basement membrane normalization in mouse grafts of human keratinocytes-implications for epidermal homeostasis. Differentiation 1997 61 3 195 209 2-s2.0-0031047074 10.1046/j.1432-0436.1997.6130195.x (Pubitemid 27099869)
170. Breitkreutz D., Schoop V. M., Mirancea N., Baur M., Stark H. J., Fusenig N. E., Epidermal differentiation and basement membrane formation by HaCaT cells in surface transplants. European Journal of Cell Biology 1998 75 3 273 286 2-s2.0-0031945960 (Pubitemid 28174652)
171. Tomakidi P., Stark H. J., Herold-Mende C., Bosch F. X., Steinbauer H., Fusenig N. E., Breitkreutz D., Discriminating expression of differentiation markers evolves in transplants of benign and malignant human skin keratinocytes through stromal interactions. Journal of Pathology 2003 200 3 298 307 2-s2.0-0038011024 10.1002/path.1366 (Pubitemid 36827303)
172. Vosseler S., Mirancea N., Bohlen P., Mueller M. M., Fusenig N. E., Angiogenesis inhibition by vascular endothelial growth factor receptor-2 blockade reduces stromal matrix metalloproteinase expression, normalizes stromal tissue, and reverts epithelial tumor phenotype in surface heterotransplants. Cancer Research 2005 65 4 1294 1305 2-s2.0-13944260479 10.1158/0008-5472.CAN-03- 3986 (Pubitemid 40270156)
173. Iyer P. V., Leong A. S. Y., Poorly differentiated squamous cell carcinomas of the skin can express vimentin. Journal of Cutaneous Pathology 1992 19 1 34 39 2-s2.0-0026532804
174. Breitkreutz D., Braiman-Wiksman L., Daum N., Denning M. F., Tennenbaum T., Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium. Journal of Cancer Research and Clinical Oncology 2007 133 11 793 808 2-s2.0-36849069894 10.1007/s00432-007-0280-3 (Pubitemid 350218916)
175. Mirancea N., Schmidt C., Daum N., Tomakidi P., Stark H. J., Fusenig N. E., Breitkreutz D., Witz I. P., Basement membrane defects in xeno-grafts of malignant human cells. Proceedings of the 2nd International Conference on Tumor Microenvironment 2002 Bologna, Italy Monduzzi 55 58
176. Kiyoshima K., Oda Y., Kinukawa N., Naito S., Tsuneyoshi M., Overexpression of laminin-5 γ 2 chain and its prognostic significance in urothelial carcinoma of urinary bladder: association with expression of cyclooxygenase 2, epidermal growth factor, and human epidermal growth factor 2. Human Pathology 2005 36 5 522 530 2-s2.0-20144386005 10.1016/j.humpath.2005.02. 013 (Pubitemid 40776005)
177. Richter P., Umbreit C., Franz M., Berndt A., Grimm S., Uecker A., Böhmer F. D., Kosmehl H., Berndt A., EGF/TGF β 1 co-stimulation of oral squamous cell carcinoma cells causes an epithelial-mesenchymal transition cell phenotype expressing laminin 332. Journal of Oral Pathology and Medicine 2011 40 1 46 54 2-s2.0-78650767258 10.1111/j.1600-0714.2010.00936.x
178. Asselineau D., Bernard B. A., Bailly C., Darmon M., Retinoic acid improves epidermal morphogenesis. Developmental Biology 1989 133 2 322 335 2-s2.0-0024375514 (Pubitemid 19151286)
179. Fleischmajer R., Perlish J. S., MacDonald E. D. II, Schechter A., Murdoch A. D., Iozzo R. V., Yamada Y., There is binding of collagen IV to β 1 integrin during early skin basement membrane assembly. Annals of the New York Academy of Sciences 1998 857 212 227 2-s2.0-0031790228 (Pubitemid 28526267)
180. Fleischmajer R., Kuroda K., Utani A., MacDonald E. D., Perlish J. S., Arikawa-Hirasawa E., Sekiguchi K., Sanzen N., Timpl R., Yamada Y., Differential expression of laminin α chains during proliferative and differentiation stages in a model for skin morphogenesis. Matrix Biology 2000 19 7 637 647 2-s2.0-0033742196 10.1016/S0945-053X(00)00092-5
181. Fleischmajer R., Utani A., MacDonald E. D. II, Perlish J. S., Pan T. C., Chu M. L., Nomizu M., Ninomiya Y., Yamada Y., Initiation of skin basement membrane formation at the epidermo-dermal interface involves assembly of laminins through binding to cell membrane receptors. Journal of Cell Science 1998 111 14 1929 1940 2-s2.0-0031847121 (Pubitemid 28391059)
182. Smola H., Stark H. J., Thiekötter G., Mirancea N., Krieg T., Fusenig N. E., Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture. Experimental Cell Research 1998 239 2 399 410 2-s2.0-0031845096 10.1006/excr.1997.3910 (Pubitemid 28366640)
183. Stark H. J., Baur M., Breitkreutz D., Mirancea N., Fusenig N. E., Organotypic keratinocyte cocultures in defined medium with regular epidermal morphogenesis and differentiation. Journal of Investigative Dermatology 1999 112 5 681 691 2-s2.0-0032896837 10.1046/j.1523-1747.1999.00573.x (Pubitemid 29220708)
184. Szabowski A., Maas-Szabowski N., Andrecht S., Kolbus A., Schorpp-Kistner M., Fusenig N. E., Angel P., c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cell 2000 103 5 745 755 2-s2.0-0034703709
185. Maas-Szabowski N., Szabowski A., Stark H. J., Andrecht S., Kolbus A., Schorpp-Kistner M., Angel P., Fusenig N. E., Organotypic cocultures with genetically modified mouse fibroblasts as a tool to dissect molecular mechanisms regulating keratinocyte growth and differentiation. Journal of Investigative Dermatology 2001 116 5 816 820 2-s2.0-0035018356 10.1046/j.1523-1747.2001.01349. x (Pubitemid 32467667)
186. Sadagurski M., Yakar S., Weingarten G., Holzenberger M., Rhodes C. J., Breitkreutz D., LeRoith D., Wertheimer E., Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation. Molecular and Cellular Biology 2006 26 7 2675 2687 2-s2.0-33645224054 10.1128/MCB.26.7.2675-2687.2006
187. Barton C. E., Johnson K. N., Mays D. M., Boehnke K., Shyr Y., Boukamp P., Pietenpol J. A., Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation. Cell Death and Disease 2010 1 9, article e74 2-s2.0-79958279335 10.1038/cddis.2010.49
188. Stark H. J., Willhauck M. J., Mirancea N., Boehnke K., Nord I., Breitkreutz D., Pavesio A., Boukamp P., Fusenig N. E., Authentic fibroblast matrix in dermal equivalents normalises epidermal histogenesis and dermo-epidermal junction in organotypic co-culture. European Journal of Cell Biology 2004 83 11-12 631 645 2-s2.0-12344315635 10.1078/0171-9335-00435 (Pubitemid 40123828)
189. Breitkreutz D., Mirancea N., Schmidt C., Beck R., Werner U., Stark H. J., Gerl M., Fusenig N. E., Inhibition of basement membrane formation by a nidogen-binding laminin γ 1-chain fragment in human skin-organotypic cocultures. Journal of Cell Science 2004 117 12 2611 2622 2-s2.0-3042733154 10.1242/jcs.01127 (Pubitemid 38877856)
190. El Ghalbzouri A., Jonkman M. F., Dijkman R., Ponec M., Basement membrane reconstruction in human skin equivalents is regulated by fibroblasts and/or exogenously activated keratinocytes. Journal of Investigative Dermatology 2005 124 1 79 86 2-s2.0-11944260893 10.1111/j.0022-202X.2004.23549.x (Pubitemid 40100951)
191. Marionnet C., Pierrard C., Vioux-Chagnoleau C., Sok J., Asselineau D., Bernerd F., Interactions between fibroblasts and keratinocytes in morphogenesis of dermal epidermal junction in a model of reconstructed skin. Journal of Investigative Dermatology 2006 126 5 971 979 2-s2.0-33646135338 10.1038/sj.jid.5700230
192. Di Nunzio F., Maruggi G., Ferrari S., Di Iorio E., Poletti V., Garcia M., Del Rio M., de Luca M., Larcher F., Pellegrini G., Mavilio F., Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors. Molecular Therapy 2008 16 12 1977 1985 2-s2.0-56749092141 10.1038/mt.2008.204
193. Murauer E. M., Gache Y., Gratz I. K., Klausegger A., Muss W., Gruber C., Meneguzzi G., Hintner H., Bauer J. W., Functional correction of type VII collagen expression in dystrophic epidermolysis bullosa. Journal of Investigative Dermatology 2011 131 1 74 83 2-s2.0-78650297492 10.1038/jid.2010.249
194. Botta A., Delteil F., Mettouchi A., Viera A., Estrach S., Négroni L., Stefani C., Lemichez E., Meneguzzi G., Gagnoux-Palaios L., Confluence switch signaling regulates ECM composition and plasmin proteolytic cascade in keratinocytes. Journal of Cell Science 2012 125 4241 4252 10.1242/jcs.096289
195. Mayer U., Mann K., Timpl R., Murphy G., Sites of nidogen cleavage by proteases involved in tissue homeostasis and remodelling. European Journal of Biochemistry 1993 217 3 877 884 2-s2.0-0027489337 10.1111/j.1432-1033.1993. tb18316.x (Pubitemid 23326868)
196. Lareu R. R., Arsianti I., Subramhanya H. K., Yanxian P., Raghunath M., In vitro enhancement of collagen matrix formation and crosslinking for applications in tissue engineering: a preliminary study. Tissue Engineering 2007 13 2 385 391 2-s2.0-33847035543 10.1089/ten.2006.0224
197. Pouliot N., Saunders N. A., Kaur P., Laminin 10/11: an alternative adhesive ligand for epidermal keratinocytes with a functional role in promoting proliferation and migration. Experimental Dermatology 2002 11 5 387 397 2-s2.0-0036781633 10.1034/j.1600-0625.2002.110501.x (Pubitemid 36934673)
198. Alexander C. M., Howard E. W., Bissell M. J., Werb Z., Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene. Journal of Cell Biology 1996 135 6 I 1669 1677 2-s2.0-0030454231
199. Pujuguet P., Simian M., Liaw J., Timpl R., Werb Z., Bissell M. J., Nidogen-1 regulates laminin-1-dependent mammary-specific gene expression. Journal of Cell Science 2000 113 5 849 858 2-s2.0-0034108469 (Pubitemid 30168653)
200. Baranowsky A., Mokkapati S., Bechtel M., Krügel J., Miosge N., Wickenhauser C., Smyth N., Nischt R., Impaired wound healing in mice lacking the basement membrane protein nidogen 1. Matrix Biology 2010 29 1 15 21 2-s2.0-73449146600 10.1016/j.matbio.2009.09.004
201. Dedhar S., Jewell K., Rojiani M., Gray V., The receptor for the basement membrane glycoprotein entactin is the integrin α 3/ β 1. The Journal of Biological Chemistry 1992 267 26 18908 18914 2-s2.0-0026725843
202. Dong L. J., Hsieh J. C., Chung A. E., Two distinct cell attachment sites in entactin are revealed by amino acid substitutions and deletion of the RGD sequence in the cysteine-rich epidermal growth factor repeat 2. The Journal of Biological Chemistry 1995 270 26 15838 15843 2-s2.0-0029072783 10.1074/jbc.270.26.15838
203. Gresham H. D., Graham I. L., Griffin G. L., Hsieh J. C., Dong L. J., Chung A. E., Senior R. M., Domain-specific interactions between entactin and neutrophil integrins: G2 domain ligation of integrin α 3 β 1 and E domain ligation of the leukocyte response integrin signal for different responses. The Journal of Biological Chemistry 1996 271 48 30587 30594 2-s2.0-0029805953 10.1074/jbc.271.48.30587 (Pubitemid 26404071)
204. Thyboll J., Kortesmaa J., Cao R., Soininen R., Wang L., Iivanainen A., Sorokin L., Risling M., Cao Y., Tryggvason K., Deletion of the laminin α 4 chain leads to impaired microvessel maturation. Molecular and Cellular Biology 2002 22 4 1194 1202 2-s2.0-0036007196 10.1128/MCB.22.4.1194-1202.2002 (Pubitemid 34094855)
205. Hallmann R., Horn N., Selg M., Wendler O., Pausch F., Sorokin L. M., Expression and function of laminins in the embryonic and mature vasculature. Physiological Reviews 2005 85 3 979 1000 2-s2.0-21244438355 10.1152/physrev. 00014.2004 (Pubitemid 40885221)
206. Stenzel D., Franco C. A., Estrach S., Mettouchi A., Sauvaget D., Rosewell I., Schertel A., Armer H., Domogatskaya A., Rodin S., Tryggvason K., Collinson L., Sorokin L., Gerhardt H., Endothelial basement membrane limits tip cell formation by inducing DII4/notch signalling in vivo. EMBO Reports 2011 12 1135 1143 10.1038/embor.2011.194
207. Zhou Z., Doi M., Wang J., Cao R., Liu B., Chan K. M., Kortesmaa J., Sorokin L., Cao Y., Tryggvason K., Deletion of laminin-8 results in increased tumor neovascularization and metastasis in mice. Cancer Research 2004 64 12 4059 4063 2-s2.0-3042663099 10.1158/0008-5472.CAN-04-0291 (Pubitemid 38802404)
208. Ortega N., Werb Z., New functional roles for non-collagenous domains of basement membrane collagens. Journal of Cell Science 2002 115 22 4201 4214 2-s2.0-0037113093 10.1242/jcs.00106 (Pubitemid 35460692)
209. O'Reilly M. S., Boehm T., Shing Y., Fukai N., Vasios G., Lane W. S., Flynn E., Birkhead J. R., Olsen B. R., Folkman J., Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997 88 2 277 285 2-s2.0-0031454617 10.1016/S0092-8674(00)81848-6 (Pubitemid 28015876)
210. Kalluri R., Basement membranes: structure, assembly and role in tumour angiogenesis. Nature Reviews Cancer 2003 3 6 422 433 2-s2.0-0037805549 10.1038/nrc1094 (Pubitemid 37328846)
211. Marneros A. G., Olsen B. R., Physiological role of collagen XVIII and endostatin. FASEB Journal 2005 19 7 716 728 2-s2.0-18144404148 10.1096/fj.04-2134rev (Pubitemid 40617376)
212. Nyberg P., Xie L., Kalluri R., Endogenous inhibitors of angiogenesis. Cancer Research 2005 65 10 3967 3979 2-s2.0-20144379162 10.1158/0008-5472.CAN- 04-2427 (Pubitemid 40775631)
213. Sund M., Hamano Y., Sugimoto H., Sudhakar A., Soubasakos M., Yerramalla U., Benjamin L. E., Lawler J., Kieran M., Shah A., Kalluri R., Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors. Proceedings of the National Academy of Sciences of the United States of America 2005 102 8 2934 2939 2-s2.0-20044386305 10.1073/pnas.0500180102 (Pubitemid 40299894)
214. Nyström A., Shaik Z. P., Gullberg D., Krieg T., Eckes B., Zent R., Pozzi A., Iozzo R. V., Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood 2009 114 23 4897 4906 2-s2.0-74049108220 10.1182/blood-2009-02-207134
215. Xie L., Duncan M. B., Pahler J., Sugimoto H., Martino M., Lively J., Mundel T., Soubasakos M., Rubin K., Takeda T., Inoue M., Lawler J., Hynes R. O., Hanahan D., Kalluri R., Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proceedings of the National Academy of Sciences of the United States of America 2011 108 24 9939 9944 10.1073/pnas.1105041108
216. Zigrino P., Ayachi O., Schild A., Kaltenberg J., Zamek J., Nischt R., Koch M., Mauch C., Loss of epidermal MMP-14 expression interferes with angiogenesis but not with re-epithelialization. European Journal of Cell Biology 2012 91 10 748 756 10.1016/j.ejcb.2012.05.003
217. Wang H., Fu W., Im J. H., Zhou Z., Santoro S. A., Iyer V., DiPersio C. M., Yu Q. C., Quaranta V., Al-Mehdi A., Muschel R. J., Tumor cell α 3 β 1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis. Journal of Cell Biology 2004 164 6 935 941 2-s2.0-4444259670 10.1083/jcb.200309112 (Pubitemid 38366904)
218. Ortiz-Urda S., Garcia J., Green C. L., Chen L., Lin Q., Veitch D. P., Sakai L. Y., Lee H., Marinkovich M. P., Khavari P. A., Type VII collagen is required for ras-driven human epidermal tumorigenesis. Science 2005 307 5716 1773 1776 2-s2.0-20144385966 10.1126/science.1106209 (Pubitemid 40388617)
219. Tran M., Rousselle P., Nokelainen P., Tallapragada S., Nguyen N. T., Fincher E. F., Marinkovich M. P., Targeting a tumor-specific laminin domain critical for human carcinogenesis. Cancer Research 2008 68 8 2885 2894 2-s2.0-42349086700 10.1158/0008-5472.CAN-07-6160 (Pubitemid 351556288)
220. Rodeck U., Uitto J., Recessive dystrophic epidermolysis bullosa-associated squamous-cell carcinoma: an enigmatic entity with complex pathogenesis. Journal of Investigative Dermatology 2007 127 10 2295 2296 2-s2.0-34848918468 10.1038/sj.jid.5700939 (Pubitemid 47619766)
221. Li J., Tzu J., Chen Y., Zhang Y. P., Nguyen N. T., Gao J., Bradley M., Keene D. R., Oro A. E., Miner J. H., Marinkovich M. P., Laminin-10 is crucial for hair morphogenesis. The EMBO Journal 2003 22 10 2400 2410 2-s2.0-0038242298 10.1093/emboj/cdg239 (Pubitemid 36604979)
222. Gao J., DeRouen M. C., Chen C. H., Nguyen M., Nguyen N. T., Ido H., Harada K., Sekiguchi K., Morgan B. A., Miner J. H., Oro A. E., Marinkovich M. P., Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes and Development 2008 22 15 2111 2124 2-s2.0-48749090218 10.1101/gad.1689908
223. Tumbar T., Guasch G., Greco V., Blanpain C., Lowry W. E., Rendl M., Fuchs R., Defining the epithelial stem cell niche in skin. Science 2004 303 5656 359 363 2-s2.0-0347634454 10.1126/science.1092436 (Pubitemid 38095773)
224. Kaur P., Interfollicular epidermal stem cells: identification, challenges, potential. Journal of Investigative Dermatology 2006 126 7 1450 1458 2-s2.0-33745182874 10.1038/sj.jid.5700184
225. Ito M., Cotsarelis G., Is the hair follicle necessary for normal wound healing? Journal of Investigative Dermatology 2008 128 5 1059 1061 2-s2.0-42149137983 10.1038/jid.2008.86 (Pubitemid 351543224)
226. Morrison S. J., Spradling A. C., Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell 2008 132 4 598 611 2-s2.0-39149144034 10.1016/j.cell.2008.01.038 (Pubitemid 351253690)
227. Hsu Y. C., Fuchs E., A family business: stem cell progeny join the niche to regulate homeostasis. Nature Reviews Molecular Cell Biology 2012 13 2 103 114 10.1038/nrm3272
228. Lund A. W., Stegemann J. P., Plopper G. E., Mesenchymal stem cells sense three dimensional type I collagen through discoidin domain receptor 1. Open Stem Cell Journal 2009 1 40 53 10.2174/1876893800901010040
229. Angstmann M., Brinkmann I., Bieback K., Breitkreutz D., Maercker C., Monitoring human mesenchymal stromal cell differentiation by electrochemical impedance sensing. Cytotherapy 2011 13 9 1074 1089 10.3109/14653249.2011.584863
230. Li S., Harrison D., Carbonetto S., Fässler R., Smyth N., Edgar D., Yurchenco P. D., Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation. Journal of Cell Biology 2002 157 7 1279 1290 2-s2.0-0037166935 10.1083/jcb.200203073 (Pubitemid 34847796)
231. Muffler S., Stark H. J., Amoros M., Falkowska-Hansen B., Boehnke K., Bühring H. J., Marmé A., Bickenbach J. R., Boukamp P., A stable niche supports long-term maintenance of human epidermal stem cells in organotypic cultures. Stem Cells 2008 26 10 2506 2515 2-s2.0-55049140193 10.1634/stemcells.2007-0991
232. Sok J., Pineau N., Dalko-Csiba M., Breton L., Bernerd F., Improvement of the dermal epidermal junction in human reconstructed skin by a new c-xylopyranoside derivative. European Journal of Dermatology 2008 18 3 297 302 2-s2.0-44949175934 10.1684/ejd.2008.0392 (Pubitemid 351821233)
233. Mayer U., Zimmermann K., Mann K., Reinhardt D., Timpl R., Nischt R., Binding properties and protease stability of recombinant human nidogen. European Journal of Biochemistry 1995 227 3 681 686 2-s2.0-0028869592 10.1111/j.1432-1033.1995.tb20188.x
234. Kruse M. N., Becker C., Lottaz D., Köhler D., Yiallouros I., Krell H. W., Sterchi E. E., Stöcker W., Human meprin α and β homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors. Biochemical Journal 2004 378 2 383 389 2-s2.0-1642362446 10.1042/BJ20031163 (Pubitemid 38367229)
235. Geurts N., Becker-Pauly C., Martens E., Proost P., Van Den Steen P. E., Stöcker W., Meprins process matrix metalloproteinase-9 (MMP-9)/gelatinase B and enhance the activation kinetics by MMP-3. The FEBS Letters 2012 586 24 4264 4269 10.1016/j.febslet.2012.10.033
236. Sage J., Leblanc-Noblesse E., Nizard C., Sasaki T., Schnebert S., Perrier E., Kurfurst R., Brömme D., Lalmanach G., Lecaille F., Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners. PLoS ONE 2012 7 8 e43494 10.1371/journal.pone.0043494