c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin

Cell

Volumn 103, Issue 5, 2000, Pages 745-755

  Szabowski, Axel ^a   Maas Szabowski, Nicole ^a   Andrecht, Sven ^a   Kolbus, Andrea ^a   Schorpp Kistner, Marina ^a   Fusenig, Norbert E ^a   Angel, Peter ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; CYTOKINE; GENE PRODUCT; PROTEIN C JUN; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL INTERACTION; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; CYTOKINE RELEASE; EPIDERMIS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMAN; HUMAN CELL; KERATINOCYTE; MESENCHYME CELL; MOUSE; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0034703709     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)00178-1     Document Type: Article

References (62)

1. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
2. Cell cycle-dependent variations in c-Jun and JunB phosphorylation: A role in the control of cyclin D1 expression
3. Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
4. Living tissue formed in vivo and accepted as skin-equivalent tissue of full thickness
5. Cytokine control of interstitial collagenase and collagenase-3 gene expression in human chondrocytes
6. Transcription factors junB and c-jun are selectively up-regulated and functionally implicated in fibrosarcoma development
7. Induction of apoptosis by the transcription factor c-Jun
8. GM-CSF activates regenerative epidermal growth and stimulates keratinocyte proliferation in human skin in vivo
9. Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha
10. Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis
11. Jun-B differs in its biological properties from, and is a negative regulator of c-Jun
12. TGF-β and retinoic acid: Regulators of growth and modifiers of differentiation in human epidermal cells
13. JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers
14. Biologic basis for interleukin-1 in disease
15. Functions of c-Jun in liver and heart development
16. Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal-epithelial interactions
17. Cloning and characterization of the promoter region of the human keratinocyte growth factor gene
18. Cell interaction and epithelial differentiation
19. Epithelial-mesenchymal interactions regulate keratinocyte growth and differentiation in vitro
20. Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice
21. Keratinocyte growth factor is required for hair development but not for wound healing
22. c-jun is essential for normal mouse development and hepatogenesis
23. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice
24. A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture
25. AP-1 function and regulation
26. Integrin expression and differentiation in transformed human epidermal cells is regulated by fibroblasts
27. c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents
28. The interleukin-1 axis in cutaneous inflammation
29. Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation
30. The role of cytokines and neuroendocrine hormones in cutaneous immunity and inflammation
31. Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism
32. Keratinocyte growth regulation in defined organotypic cultures through IL-1-induced KGF expression in resting fibroblasts
33. Cell-cell signalling in the regulation of blood cell formation and function
34. The biological consequences of excess GM-CSF levels in transgenic mice also lacking high-affinity receptors for GM-CSF
35. Determination of ligand-binding specificity by alternative splicing: Two distinct growth factor receptors encoded by a single gene
36. Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1
37. JunB negatively regulates cell proliferation by transcriptionally activating p16(INK4a)expression
38. Epithelial growth factor and temperature regulate keratinocyte differentiation
39. Correlation between hyperproliferation and suprabasal integrin expression in human epidermis reconstituted in culture
40. Purification and characterization of a newly identified growth factor specific for epithelial cells
41. c-fos is required for malignant progression of skin tumors
42. Psoriatic fibroblasts induce hyperproliferation of normal keratinocytes in a skin equivalent model in vitro
43. JunB is essential for mammalian placentation
44. Control of cell cycle progression by c-Jun is p53 dependent
45. Cytokine networks in the skin
46. Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice
47. jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun
48. Mutual induction of growth factor gene expression by epidermal-dermal cell interaction
49. Dynamics of basement membrane formation by keratinocyte-fibroblast interactions in organotypic skin culture
50. Organotypic keratinocyte cocultures in defined medium with regular epidermal morphogenesis and differentiation
51. Low molecular weight heparin; a novel alternative therapeutic approach for lichen planus
52. Induction of Interleukin-1α and -β gene expression in human keratinocytes exposed to repetitive strain: Their role in strain-induced keratinocyte proliferation and morphological change
53. Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors
54. Differential expression of the fos and jun family members c-fos, fosB, Fra-1, Fra-2, c-jun, junB and junD during human epidermal keratinocyte differentiation
55. Large induction of keratinocyte growth factor expression in the dermis during wound healing
56. The role of KGF in morphogenesis of epithelium and re-epithelialization of wounds
57. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
58. c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms
59. Intradermal transgenic expression of granulocyte-macrophage colony-stimulating factor induces neutrophilia, epidermal hyperplasia, Langerhans' cell/macrophage accumulation, and dermal fibrosis
60. Characterization of the human granulocyte-macrophage colony-stimulating factor gene promoter: An AP1 complex and an Sp1-related complex transactivate the promoter activity that is suppressed by a YY1 complex
61. Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion