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Volumn 1, Issue 9, 2010, Pages

Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation

Author keywords

Cytokines; FGF10; GM CSF; KGF; P53; P73

Indexed keywords

ACTIN; ALDEHYDE DEHYDROGENASE ISOENZYME 2; ARTEMIN; BASAL CELL ADHESION MOLECULE PROTEIN; BETA TUBULIN; CLAUDIN 1; CYTOKERATIN 2; FIBROBLAST GROWTH FACTOR 10; FILAGGRIN; GLUCOSE TRANSPORTER 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; INVOLUCRIN; JAGGED1; LORICRIN; METASTASIS SUPPRESSOR 1 PROTEIN; METAXIN 1; OXYSTEROL BINDING PROTEIN LIKE 3; P CADHERIN; PROTEIN; PROTEIN MDM2; PROTEIN P21; PROTEIN P63; PROTEIN P73; S100A2 PROTEIN; SOMATOMEDIN BINDING PROTEIN 3; STRATIFIN; TRANSCRIPTION FACTOR RUNX1; TRISTETRAPROLIN; UNCLASSIFIED DRUG; UVOMORULIN; SMALL INTERFERING RNA; TCF7L1 PROTEIN, HUMAN; TP63 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 1; TUMOR SUPPRESSOR PROTEIN;

EID: 79958279335     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2010.49     Document Type: Article
Times cited : (55)

References (40)
  • 2
    • 0033594491 scopus 로고    scopus 로고
    • P63 is a p53 homologue required for limb and epidermal morphogenesis
    • DOI 10.1038/19531
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999; 398: 708-713. (Pubitemid 29197649)
    • (1999) Nature , vol.398 , Issue.6729 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.-J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 3
    • 0037377761 scopus 로고    scopus 로고
    • The ΔNp63α phosphoprotein binds the p21 and 14-3-3σ promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • DOI 10.1128/MCB.23.7.2264-2276.2003
    • Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA. The delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 2003; 23: 2264-2276. (Pubitemid 36351010)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.7 , pp. 2264-2276
    • Westfall, M.D.1    Mays, D.J.2    Sniezek, J.C.3    Pietenpol, J.A.4
  • 4
    • 33747872417 scopus 로고    scopus 로고
    • Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis
    • DOI 10.1158/0008-5472.CAN-06-2020
    • Barbieri CE, Tang LJ, Brown KA, Pietenpol JA. Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis. Cancer Res 2006; 66: 7589-7597. (Pubitemid 44289215)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7589-7597
    • Barbieri, C.E.1    Tang, L.J.2    Brown, K.A.3    Pietenpol, J.A.4
  • 6
    • 0032161624 scopus 로고    scopus 로고
    • P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominantnegative activities. Mol Cell 1998; 2: 305-316. (Pubitemid 128379271)
    • (1998) Molecular Cell , vol.2 , Issue.3 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6    Andrews, N.C.7    Caput, D.8    McKeon, F.9
  • 7
    • 0037804687 scopus 로고    scopus 로고
    • ΔNp63α functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes
    • DOI 10.1038/sj.onc.1206536
    • King KE, Ponnamperuma RM, Yamashita T, Tokino T, Lee LA, Young MF et al. DeltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes. Oncogene 2003; 22: 3635-3644. (Pubitemid 36765323)
    • (2003) Oncogene , vol.22 , Issue.23 , pp. 3635-3644
    • King, K.E.1    Ponnamperuma, R.M.2    Yamashita, T.3    Tokino, T.4    Lee, L.A.5    Young, M.F.6    Weinberg, W.C.7
  • 8
    • 33646365381 scopus 로고    scopus 로고
    • 2-terminally deleted (ΔN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the ΔN variant of p63
    • DOI 10.1074/jbc.M507964200
    • Helton ES, Zhu J, Chen X. The unique NH2-terminally deleted (deltaN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the deltaN variant of p63. J Biol Chem 2006; 281: 2533-2542. (Pubitemid 43845713)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.5 , pp. 2533-2542
    • Helton, E.S.1    Zhu, J.2    Chen, X.3
  • 11
    • 47949105620 scopus 로고    scopus 로고
    • Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells
    • Li N, Singh S, Cherukuri P, Li H, Yuan Z, Ellisen LW et al. Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells. Stem Cells (Dayton, OH) 2008; 26: 1253-1264.
    • (2008) Stem Cells (Dayton, OH) , vol.26 , pp. 1253-1264
    • Li, N.1    Singh, S.2    Cherukuri, P.3    Li, H.4    Yuan, Z.5    Ellisen, L.W.6
  • 12
    • 0942301281 scopus 로고    scopus 로고
    • P63 is the molecular switch for initiation of an epithelial stratification program
    • DOI 10.1101/gad.1165104
    • Koster MI, Kim S, Mills AA, DeMayo FJ, Roop DR. p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev 2004; 18: 126-131. (Pubitemid 38141780)
    • (2004) Genes and Development , vol.18 , Issue.2 , pp. 126-131
    • Koster, M.I.1    Kim, S.2    Mills, A.A.3    DeMayo, F.J.4    Roop, D.R.5
  • 13
    • 16844386318 scopus 로고    scopus 로고
    • IGFBP-3 is a direct target of transcriptional regulation by ΔNp63α in squamous epithelium
    • DOI 10.1158/0008-5472.CAN-04-3449
    • Barbieri CE, Perez CA, Johnson KN, Ely KA, Billheimer D, Pietenpol JA. IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium. Cancer Res 2005; 65: 2314-2320. (Pubitemid 40490141)
    • (2005) Cancer Research , vol.65 , Issue.6 , pp. 2314-2320
    • Barbieri, C.E.1    Perez, C.A.2    Johnson, K.N.3    Ely, K.A.4    Billheimer, D.5    Pietenpol, J.A.6
  • 15
    • 36148979729 scopus 로고    scopus 로고
    • P63 consensus DNA-binding site: Identification, analysis and application into a p63MH algorithm
    • DOI 10.1038/sj.onc.1210561, PII 1210561
    • Perez CA, Ott J, Mays DJ, Pietenpol JA. p63 consensus DNA-binding site: identification, analysis and application into a p63MH algorithm. Oncogene 2007; 26: 7363-7370. (Pubitemid 350115981)
    • (2007) Oncogene , vol.26 , Issue.52 , pp. 7363-7370
    • Perez, C.A.1    Ott, J.2    Mays, D.J.3    Pietenpol, J.A.4
  • 16
    • 46949086501 scopus 로고    scopus 로고
    • A chromatin immunoprecipitation screen in mouse keratinocytes reveals Runx1 as a direct transcriptional target of ΔNp63
    • DOI 10.1002/jcb.21700
    • Ortt K, Raveh E, Gat U, Sinha S. A chromatin immunoprecipitation screen in mouse keratinocytes reveals Runx1 as a direct transcriptional target of DeltaNp63. J Cell Biochem 2008; 104: 1204-1219. (Pubitemid 351961695)
    • (2008) Journal of Cellular Biochemistry , vol.104 , Issue.4 , pp. 1204-1219
    • Ortt, K.1    Raveh, E.2    Gat, U.3    Sinha, S.4
  • 17
    • 33847057887 scopus 로고    scopus 로고
    • Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells
    • DOI 10.1016/j.molcel.2006.10.018
    • Yang A, Zhu Z, Kapranov P, McKeon F, Church GM, Gingeras TR et al. Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells. Mol Cell 2006; 24: 593-602. (Pubitemid 350284225)
    • (2006) Molecular Cell , vol.24 , Issue.4 , pp. 593-602
    • Yang, A.1    Zhu, Z.2    Kapranov, P.3    McKeon, F.4    Church, G.M.5    Gingeras, T.R.6    Struhl, K.7
  • 19
    • 33751230475 scopus 로고    scopus 로고
    • P63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • DOI 10.1101/gad.1463206
    • Truong AB, Kretz M, Ridky TW, Kimmel R, Khavari PA. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev 2006; 20: 3185-3197. (Pubitemid 44790632)
    • (2006) Genes and Development , vol.20 , Issue.22 , pp. 3185-3197
    • Truong, A.B.1    Kretz, M.2    Ridky, T.W.3    Kimmel, R.4    Khavari, P.A.5
  • 23
    • 63049136592 scopus 로고    scopus 로고
    • A mutant-p53/ Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B et al. A mutant-p53/ Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 2009; 137: 87-98.
    • (2009) Cell , vol.137 , pp. 87-98
    • Adorno, M.1    Cordenonsi, M.2    Montagner, M.3    Dupont, S.4    Wong, C.5    Hann, B.6
  • 24
    • 33646797744 scopus 로고    scopus 로고
    • Differential roles of p63 isoforms in epidermal development: Selective genetic complementation in p63 null mice
    • Candi E, Rufini A, Terrinoni A, Dinsdale D, Ranalli M, Paradisi A et al. Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice. Cell Death Differ 2006; 13: 1037-1047.
    • (2006) Cell Death Differ , vol.13 , pp. 1037-1047
    • Candi, E.1    Rufini, A.2    Terrinoni, A.3    Dinsdale, D.4    Ranalli, M.5    Paradisi, A.6
  • 28
    • 0029855829 scopus 로고    scopus 로고
    • Interleukin-1-induced growth factor expression in postmitotic and resting fibroblasts
    • Maas-Szabowski N, Fusenig NE. Interleukin-1-induced growth factor expression in postmitotic and resting fibroblasts. J Invest Dermatol 1996; 107: 849-855. (Pubitemid 26408203)
    • (1996) Journal of Investigative Dermatology , vol.107 , Issue.6 , pp. 849-855
    • Maas-Szabowski, N.1    Fusenig, N.E.2
  • 29
    • 0032768526 scopus 로고    scopus 로고
    • Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism
    • Maas-Szabowski N, Shimotoyodome A, Fusenig NE. Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism. J Cell Sci 1999; 112 (Part 12): 1843-1853. (Pubitemid 29338810)
    • (1999) Journal of Cell Science , vol.112 , Issue.12 , pp. 1843-1853
    • Maas-Szabowski, N.1    Shimotoyodome, A.2    Fusenig, N.E.3
  • 31
    • 0025091158 scopus 로고
    • Human keratinocyte growth factor activity on proliferation and differentiation of human keratinocytes: Differentiation response distinguishes KGF from EGF family
    • Marchese C, Rubin J, Ron D, Faggioni A, Torrisi MR, Messina A et al. Human keratinocyte growth factor activity on proliferation and differentiation of human keratinocytes: differentiation response distinguishes KGF from EGF family. J Cell Physiol 1990; 144: 326-332.
    • (1990) J Cell Physiol , vol.144 , pp. 326-332
    • Marchese, C.1    Rubin, J.2    Ron, D.3    Faggioni, A.4    Torrisi, M.R.5    Messina, A.6
  • 32
    • 0035395874 scopus 로고    scopus 로고
    • Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
    • DOI 10.1101/gad.891401
    • Merrill BJ, Gat U, DasGupta R, Fuchs E. Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev 2001; 15: 1688-1705. (Pubitemid 32702590)
    • (2001) Genes and Development , vol.15 , Issue.13 , pp. 1688-1705
    • Merrill, B.J.1    Gat, U.2    DasGupta, R.3    Fuchs, E.4
  • 33
    • 33749065765 scopus 로고    scopus 로고
    • Tcf3 Governs Stem Cell Features and Represses Cell Fate Determination in Skin
    • DOI 10.1016/j.cell.2006.07.036, PII S0092867406011627
    • Nguyen H, Rendl M, Fuchs E. Tcf3 governs stem cell features and represses cell fate determination in skin. Cell 2006; 127: 171-183. (Pubitemid 44466637)
    • (2006) Cell , vol.127 , Issue.1 , pp. 171-183
    • Nguyen, H.1    Rendl, M.2    Fuchs, E.3
  • 40
    • 0041842714 scopus 로고    scopus 로고
    • Constitutive overexpression of human telomerase reverse transcriptase but not c-myc blocks terminal differentiation in human HaCaT skin keratinocytes
    • DOI 10.1046/j.1523-1747.2003.12304.x
    • Cerezo A, Stark HJ, Moshir S, Boukamp P. Constitutive overexpression of human telomerase reverse transcriptase but not c-myc blocks terminal differentiation in human HaCaT skin keratinocytes. J Invest Dermatol 2003; 121: 110-119. (Pubitemid 36900462)
    • (2003) Journal of Investigative Dermatology , vol.121 , Issue.1 , pp. 110-119
    • Cerezo, A.1    Stark, H.-J.2    Moshir, S.3    Boukamp, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.