메뉴 건너뛰기




Volumn 24, Issue 6, 2005, Pages 1146-1156

E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions

Author keywords

E cadherin; Epidermal barrier; Gene targeting; Polarity; Tight junctions

Indexed keywords

CELL ADHESION MOLECULE; PROTEIN KINASE C; RAC PROTEIN; UVOMORULIN;

EID: 17144431742     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600605     Document Type: Article
Times cited : (371)

References (53)
  • 2
    • 0037228253 scopus 로고    scopus 로고
    • Integrated activity of PDZ protein complexes regulates epithelial polarity
    • Bilder D, Schober M, Perrimon N (2003) Integrated activity of PDZ protein complexes regulates epithelial polarity. Nat Cell Biol 5: 53-58
    • (2003) Nat Cell Biol , vol.5 , pp. 53-58
    • Bilder, D.1    Schober, M.2    Perrimon, N.3
  • 3
    • 0036269067 scopus 로고    scopus 로고
    • E-cadherin is a survival factor for the lactating mouse mammary gland
    • Boussadia O, Kutsch S, Hierholzer A, Delmas V, Kemler R (2002) E-cadherin is a survival factor for the lactating mouse mammary gland. Mech Dev 115: 53-62
    • (2002) Mech Dev , vol.115 , pp. 53-62
    • Boussadia, O.1    Kutsch, S.2    Hierholzer, A.3    Delmas, V.4    Kemler, R.5
  • 4
    • 0036774217 scopus 로고    scopus 로고
    • Cell-cell adhesion and signalling
    • Braga VM (2002) Cell-cell adhesion and signalling. Curr Opin Cell Biol 14: 546-556
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 546-556
    • Braga, V.M.1
  • 6
    • 0038701734 scopus 로고    scopus 로고
    • Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture
    • Colegio OR, Van Itallie C, Rahner C, Anderson JM (2003) Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture. Am J Physiol Cell Physiol 284: C1346-C1354
    • (2003) Am J Physiol Cell Physiol , vol.284
    • Colegio, O.R.1    Van Itallie, C.2    Rahner, C.3    Anderson, J.M.4
  • 7
    • 0030014526 scopus 로고    scopus 로고
    • Armadillo is required for adherens junction assembly, cell polarity, and morphogenesis during Drosophila embryogenesis
    • Cox RT, Kirkpatrick C, Peifer M (1996) Armadillo is required for adherens junction assembly, cell polarity, and morphogenesis during Drosophila embryogenesis. J Cell Biol 134: 133-148
    • (1996) J Cell Biol , vol.134 , pp. 133-148
    • Cox, R.T.1    Kirkpatrick, C.2    Peifer, M.3
  • 8
    • 0346025727 scopus 로고    scopus 로고
    • Junctional adhesion molecules (JAMs): More molecules with dual functions?
    • Ebnet K, Suzuki A, Ohno S, Vestweber D (2004) Junctional adhesion molecules (JAMs): more molecules with dual functions? J Cell Sci 117: 19-29
    • (2004) J Cell Sci , vol.117 , pp. 19-29
    • Ebnet, K.1    Suzuki, A.2    Ohno, S.3    Vestweber, D.4
  • 9
    • 0036696823 scopus 로고    scopus 로고
    • Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion
    • Ehrlich JS, Hansen MD, Nelson WJ (2002) Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion. Dev Cell 3: 259-270
    • (2002) Dev Cell , vol.3 , pp. 259-270
    • Ehrlich, J.S.1    Hansen, M.D.2    Nelson, W.J.3
  • 10
    • 0032491391 scopus 로고    scopus 로고
    • The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
    • Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM (1998) The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem 273: 29745-29753
    • (1998) J Biol Chem , vol.273 , pp. 29745-29753
    • Fanning, A.S.1    Jameson, B.J.2    Jesaitis, L.A.3    Anderson, J.M.4
  • 11
    • 0022404897 scopus 로고
    • Epithelial and subepithelial contributions to transmural electrical resistance of intact rat jejunum, in vitro
    • Fromm M, Schulzke JD, Hegel U (1985) Epithelial and subepithelial contributions to transmural electrical resistance of intact rat jejunum, in vitro. Pflugers Arch 405: 400-402
    • (1985) Pflugers Arch , vol.405 , pp. 400-402
    • Fromm, M.1    Schulzke, J.D.2    Hegel, U.3
  • 12
    • 0037128938 scopus 로고    scopus 로고
    • Claudin-based tight junctions are crucial for the mammalian epidermal barrier: A lesson from claudin-1-deficient mice
    • Furuse M, Hata M, Furuse K, Yoshida Y, Haratake A, Sugitani Y, Noda T, Kubo A, Tsukita S (2002) Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol 156: 1099-1111
    • (2002) J Cell Biol , vol.156 , pp. 1099-1111
    • Furuse, M.1    Hata, M.2    Furuse, K.3    Yoshida, Y.4    Haratake, A.5    Sugitani, Y.6    Noda, T.7    Kubo, A.8    Tsukita, S.9
  • 13
    • 1842733459 scopus 로고    scopus 로고
    • Working out the strength and flexibility of desmosomes
    • Getsios S, Huen AC, Green KJ (2004) Working out the strength and flexibility of desmosomes. Nat Rev Mol Cell Biol 5: 271-281
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 271-281
    • Getsios, S.1    Huen, A.C.2    Green, K.J.3
  • 14
    • 0030875296 scopus 로고    scopus 로고
    • Ussing chamber for high-frequency transmural impedance analysis of epithelial tissues
    • Gitter AH, Schulzke JD, Sorgenfrei D, Fromm M (1997) Ussing chamber for high-frequency transmural impedance analysis of epithelial tissues. J Biochem Biophys Methods 35: 81-88
    • (1997) J Biochem Biophys Methods , vol.35 , pp. 81-88
    • Gitter, A.H.1    Schulzke, J.D.2    Sorgenfrei, D.3    Fromm, M.4
  • 16
    • 0024095524 scopus 로고
    • The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex
    • Gumbiner B, Stevenson B, Grimaldi A (1988) The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J Cell Biol 107: 1575-1587
    • (1988) J Cell Biol , vol.107 , pp. 1575-1587
    • Gumbiner, B.1    Stevenson, B.2    Grimaldi, A.3
  • 18
    • 0031865846 scopus 로고    scopus 로고
    • Patterned acquisition of skin barrier function during development
    • Hardman MJ, Sisi P, Banbury DN, Byrne C (1998) Patterned acquisition of skin barrier function during development. Development 125: 1541-1552
    • (1998) Development , vol.125 , pp. 1541-1552
    • Hardman, M.J.1    Sisi, P.2    Banbury, D.N.3    Byrne, C.4
  • 20
    • 0033376599 scopus 로고    scopus 로고
    • Claudin-1 contributes to the epithelial barrier function in MDCK cells
    • Inai T, Kobayashi J, Shibata Y (1999) Claudin-1 contributes to the epithelial barrier function in MDCK cells. Eur J Cell Biol 78: 849-855
    • (1999) Eur J Cell Biol , vol.78 , pp. 849-855
    • Inai, T.1    Kobayashi, J.2    Shibata, Y.3
  • 21
    • 0033552629 scopus 로고    scopus 로고
    • Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins
    • Itoh M, Furuse M, Morita K, Kubota K, Saitou M, Tsukita S (1999) Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol 147: 1351-1363
    • (1999) J Cell Biol , vol.147 , pp. 1351-1363
    • Itoh, M.1    Furuse, M.2    Morita, K.3    Kubota, K.4    Saitou, M.5    Tsukita, S.6
  • 22
    • 0030748548 scopus 로고    scopus 로고
    • Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments
    • Itoh M, Nagafuchi A, Moroi S, Tsukita S (1997) Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol 138: 181-192
    • (1997) J Cell Biol , vol.138 , pp. 181-192
    • Itoh, M.1    Nagafuchi, A.2    Moroi, S.3    Tsukita, S.4
  • 23
    • 0030895772 scopus 로고    scopus 로고
    • E-cadherin and P-cadherin have partially redundant roles in human epidermal stratification
    • Jensen PJ, Telegan B, Lavker RM, Wheelock MJ (1997) E-cadherin and P-cadherin have partially redundant roles in human epidermal stratification. Cell Tissue Res 288: 307-316
    • (1997) Cell Tissue Res , vol.288 , pp. 307-316
    • Jensen, P.J.1    Telegan, B.2    Lavker, R.M.3    Wheelock, M.J.4
  • 24
    • 0034253536 scopus 로고    scopus 로고
    • The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
    • Joberty G, Petersen C, Gao L, Macara IG (2000) The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol 2: 531-539
    • (2000) Nat Cell Biol , vol.2 , pp. 531-539
    • Joberty, G.1    Petersen, C.2    Gao, L.3    Macara, I.G.4
  • 25
    • 0033790539 scopus 로고    scopus 로고
    • The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1
    • Johansson A, Driessens M, Aspenstrom P (2000) The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1. J Cell Sci 113: 3267-3275
    • (2000) J Cell Sci , vol.113 , pp. 3267-3275
    • Johansson, A.1    Driessens, M.2    Aspenstrom, P.3
  • 26
    • 0032514134 scopus 로고    scopus 로고
    • Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases
    • Jou TS, Schneeberger EE, Nelson WJ (1998) Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases. J Cell Biol 142: 101-115
    • (1998) J Cell Biol , vol.142 , pp. 101-115
    • Jou, T.S.1    Schneeberger, E.E.2    Nelson, W.J.3
  • 27
    • 0034711219 scopus 로고    scopus 로고
    • E-cadherin-mediated cell-cell attachment activates Cdc42
    • Kim SH, Li Z, Sacks DB (2000) E-cadherin-mediated cell-cell attachment activates Cdc42. J Biol Chem 275: 36999-37005
    • (2000) J Biol Chem , vol.275 , pp. 36999-37005
    • Kim, S.H.1    Li, Z.2    Sacks, D.B.3
  • 29
    • 0028059290 scopus 로고
    • E-cadherin null mutant embryos fail to form a trophectoderm epithelium
    • Larue L, Ohsugi M, Hirchenhain J, Kemler R (1994) E-cadherin null mutant embryos fail to form a trophectoderm epithelium. Proc Natl Acad Sci USA 91: 8263-8267
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8263-8267
    • Larue, L.1    Ohsugi, M.2    Hirchenhain, J.3    Kemler, R.4
  • 30
    • 0000202186 scopus 로고    scopus 로고
    • A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity
    • Lin D, Edwards AS, Fawcett JP, Mbamalu G, Scott JD, Pawson T (2000) A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nat Cell Biol 2: 540-547
    • (2000) Nat Cell Biol , vol.2 , pp. 540-547
    • Lin, D.1    Edwards, A.S.2    Fawcett, J.P.3    Mbamalu, G.4    Scott, J.D.5    Pawson, T.6
  • 31
    • 1542374119 scopus 로고    scopus 로고
    • Parsing the polarity code
    • Macara IG (2004) Parsing the polarity code. Nat Rev Mol Cell Biol 5: 220-231
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 220-231
    • Macara, I.G.1
  • 33
    • 0029903396 scopus 로고    scopus 로고
    • Armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila
    • Muller HA, Wieschaus E (1996) armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila. J Cell Biol 134: 149-163
    • (1996) J Cell Biol , vol.134 , pp. 149-163
    • Muller, H.A.1    Wieschaus, E.2
  • 34
    • 0025155347 scopus 로고
    • Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines
    • Musil LS, Cunningham BA, Edelman GM, Goodenough DA (1990) Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines. J Cell Biol 111: 2077-2088
    • (1990) J Cell Biol , vol.111 , pp. 2077-2088
    • Musil, L.S.1    Cunningham, B.A.2    Edelman, G.M.3    Goodenough, D.A.4
  • 35
    • 0037452071 scopus 로고    scopus 로고
    • Adaptation of core mechanisms to generate cell polarity
    • Nelson WJ (2003) Adaptation of core mechanisms to generate cell polarity. Nature 422: 766-774
    • (2003) Nature , vol.422 , pp. 766-774
    • Nelson, W.J.1
  • 36
    • 0033620472 scopus 로고    scopus 로고
    • Bricks and mortar of the epidermal barrier
    • Nemes Z, Steinert PM (1999) Bricks and mortar of the epidermal barrier. Exp Mol Med 31: 5-19
    • (1999) Exp Mol Med , vol.31 , pp. 5-19
    • Nemes, Z.1    Steinert, P.M.2
  • 38
    • 0037459077 scopus 로고    scopus 로고
    • Sticky business: Orchestrating cellular signals at adherens junctions
    • Perez-Moreno M, Jamora C, Fuchs E (2003) Sticky business: orchestrating cellular signals at adherens junctions. Cell 112: 535-548
    • (2003) Cell , vol.112 , pp. 535-548
    • Perez-Moreno, M.1    Jamora, C.2    Fuchs, E.3
  • 40
    • 0035725214 scopus 로고    scopus 로고
    • Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes
    • Pummi K, Malminen M, Karvonene SL, Peltonen J, Peltonen S (2001) Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes. J Invest Dermatol 117: 1050-1057
    • (2001) J Invest Dermatol , vol.117 , pp. 1050-1057
    • Pummi, K.1    Malminen, M.2    Karvonene, S.L.3    Peltonen, J.4    Peltonen, S.5
  • 41
    • 7944227353 scopus 로고    scopus 로고
    • Emerging roles for p120-catenin in cell adhesion and cancer
    • Reynolds AB, Roczniak-Ferguson A (2004) Emerging roles for p120-catenin in cell adhesion and cancer. Oncogene 23: 7947-7956
    • (2004) Oncogene , vol.23 , pp. 7947-7956
    • Reynolds, A.B.1    Roczniak-Ferguson, A.2
  • 42
    • 0028981208 scopus 로고
    • Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex
    • Rimm DL, Koslov ER, Kebriaei P, Cianci CD, Morrow JS (1995) Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc Natl Acad Sci USA 92: 8813-8817
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8813-8817
    • Rimm, D.L.1    Koslov, E.R.2    Kebriaei, P.3    Cianci, C.D.4    Morrow, J.S.5
  • 43
    • 0037106581 scopus 로고    scopus 로고
    • aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization
    • Suzuki A, Ishiyama C, Hashiba K, Shimizu M, Ebnet K, Ohno S (2002) aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization. J Cell Sci 115: 3565-3573
    • (2002) J Cell Sci , vol.115 , pp. 3565-3573
    • Suzuki, A.1    Ishiyama, C.2    Hashiba, K.3    Shimizu, M.4    Ebnet, K.5    Ohno, S.6
  • 44
    • 0034645049 scopus 로고    scopus 로고
    • Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis
    • Tanentzapf G, Smith C, McGlade J, Tepass U (2000) Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis. J Cell Biol 151: 891-904
    • (2000) J Cell Biol , vol.151 , pp. 891-904
    • Tanentzapf, G.1    Smith, C.2    McGlade, J.3    Tepass, U.4
  • 45
    • 0037225708 scopus 로고    scopus 로고
    • Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization
    • Tanentzapf G, Tepass U (2003) Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization. Nat Cell Biol 5: 46-52
    • (2003) Nat Cell Biol , vol.5 , pp. 46-52
    • Tanentzapf, G.1    Tepass, U.2
  • 46
    • 0346374819 scopus 로고    scopus 로고
    • Conditional targeting of E-cadherin in skin: Insights into hyperproliferative and degenerative responses
    • Tinkle CL, Lechler T, Pasolli HA, Fuchs E (2004) Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. Proc Natl Acad Sci USA 101: 552-557
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 552-557
    • Tinkle, C.L.1    Lechler, T.2    Pasolli, H.A.3    Fuchs, E.4
  • 47
    • 0036336486 scopus 로고    scopus 로고
    • Permeability barrier dysfunction in transgenic mice overexpressing claudin 6
    • Turksen K, Troy TC (2002) Permeability barrier dysfunction in transgenic mice overexpressing claudin 6. Development 129: 1775-1784
    • (2002) Development , vol.129 , pp. 1775-1784
    • Turksen, K.1    Troy, T.C.2
  • 48
    • 7244219999 scopus 로고    scopus 로고
    • Establishment and characterization of cultured epithelial cells lacking expression of ZO-1
    • Umeda K, Matsui T, Nakayama M, Furuse K, Sasaki H, Furuse M, Tsukita S (2004) Establishment and characterization of cultured epithelial cells lacking expression of ZO-1. J Biol Chem 279: 44785-44794
    • (2004) J Biol Chem , vol.279 , pp. 44785-44794
    • Umeda, K.1    Matsui, T.2    Nakayama, M.3    Furuse, K.4    Sasaki, H.5    Furuse, M.6    Tsukita, S.7
  • 49
    • 0035936807 scopus 로고    scopus 로고
    • Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin
    • Vasioukhin V, Bauer C, Degenstein L, Wise B, Fuchs E (2001) Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin. Cell 104: 605-617
    • (2001) Cell , vol.104 , pp. 605-617
    • Vasioukhin, V.1    Bauer, C.2    Degenstein, L.3    Wise, B.4    Fuchs, E.5
  • 50
    • 0028129695 scopus 로고
    • Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line
    • Watabe M, Nagafuchi A, Tsukita S, Takeichi M (1994) Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J Cell Biol 127: 247-256
    • (1994) J Cell Biol , vol.127 , pp. 247-256
    • Watabe, M.1    Nagafuchi, A.2    Tsukita, S.3    Takeichi, M.4
  • 51
    • 0035427373 scopus 로고    scopus 로고
    • Stem cell fate and patterning in mammalian epidermis
    • Watt FM (2001) Stem cell fate and patterning in mammalian epidermis. Curr Opin Genet Dev 11: 410-417
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 410-417
    • Watt, F.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.