-
1
-
-
78649976005
-
An integrated approach to uncover drivers of cancer
-
Akavia U.D., Litvin O., et al. An integrated approach to uncover drivers of cancer. Cell 2010, 143(6):1005-1017.
-
(2010)
Cell
, vol.143
, Issue.6
, pp. 1005-1017
-
-
Akavia, U.D.1
Litvin, O.2
-
2
-
-
0037096906
-
The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade
-
Albuquerque C., Breukel C., et al. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade. Human Molecular Genetics 2002, 11(13):1549-1560.
-
(2002)
Human Molecular Genetics
, vol.11
, Issue.13
, pp. 1549-1560
-
-
Albuquerque, C.1
Breukel, C.2
-
3
-
-
20244387973
-
Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine
-
Andreu P., Colnot S., et al. Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine. Development 2005, 132(6):1443-1451.
-
(2005)
Development
, vol.132
, Issue.6
, pp. 1443-1451
-
-
Andreu, P.1
Colnot, S.2
-
4
-
-
0033636480
-
Hereditary non-polyposis colorectal cancer: an updated review
-
Anwar S., Hall C., et al. Hereditary non-polyposis colorectal cancer: an updated review. European Journal of Surgical Oncology 2000, 26(7):635-645.
-
(2000)
European Journal of Surgical Oncology
, vol.26
, Issue.7
, pp. 635-645
-
-
Anwar, S.1
Hall, C.2
-
5
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Barker N., Van Es J.H., et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 2007, 449(7165):1003-1007.
-
(2007)
Nature
, vol.449
, Issue.7165
, pp. 1003-1007
-
-
Barker, N.1
Van Es, J.H.2
-
6
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker N., Ridgway R.A., et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 2008, 457(7229):608-611.
-
(2008)
Nature
, vol.457
, Issue.7229
, pp. 608-611
-
-
Barker, N.1
Ridgway, R.A.2
-
7
-
-
21344460054
-
EphB receptor activity suppresses colorectal cancer progression
-
Batlle E., Bacani J., et al. EphB receptor activity suppresses colorectal cancer progression. Nature 2005, 435(7045):1126-1130.
-
(2005)
Nature
, vol.435
, Issue.7045
, pp. 1126-1130
-
-
Batlle, E.1
Bacani, J.2
-
8
-
-
77956624470
-
TGF-β signaling alterations and colon cancer
-
Bellam N., Pasche B. TGF-β signaling alterations and colon cancer. Cancer Genetics 2010, 155:85-103.
-
(2010)
Cancer Genetics
, vol.155
, pp. 85-103
-
-
Bellam, N.1
Pasche, B.2
-
9
-
-
0023256456
-
Prevalence of ras gene mutations in human colorectal cancers
-
Bos J.L., Fearon E.R., et al. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987, 327(6120):293-297.
-
(1987)
Nature
, vol.327
, Issue.6120
, pp. 293-297
-
-
Bos, J.L.1
Fearon, E.R.2
-
10
-
-
77957815238
-
The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis
-
Casorelli I., Pannellini T., et al. The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis. PLoS One 2010, 5(8):e12070.
-
(2010)
PLoS One
, vol.5
, Issue.8
-
-
Casorelli, I.1
Pannellini, T.2
-
11
-
-
33947326117
-
Estrogen receptors α and β are inhibitory modifiers of Apc-dependent tumorigenesis in the proximal colon of Min/+ mice
-
Cho N.L., Javid S.H., et al. Estrogen receptors α and β are inhibitory modifiers of Apc-dependent tumorigenesis in the proximal colon of Min/+ mice. Cancer Research 2007, 67(5):2366-2372.
-
(2007)
Cancer Research
, vol.67
, Issue.5
, pp. 2366-2372
-
-
Cho, N.L.1
Javid, S.H.2
-
12
-
-
0034282465
-
Genetic disruption of Ptgs-1, as well as of Ptgs-2, reduces intestinal tumorigenesis in Min mice
-
Chulada P.C., Thompson M.B., et al. Genetic disruption of Ptgs-1, as well as of Ptgs-2, reduces intestinal tumorigenesis in Min mice. Cancer Research 2000, 60(17):4705-4708.
-
(2000)
Cancer Research
, vol.60
, Issue.17
, pp. 4705-4708
-
-
Chulada, P.C.1
Thompson, M.B.2
-
13
-
-
0028792347
-
Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy
-
Clarke A.R., Cummings M.C., et al. Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy. Oncogene 1995, 11(9):1913-1920.
-
(1995)
Oncogene
, vol.11
, Issue.9
, pp. 1913-1920
-
-
Clarke, A.R.1
Cummings, M.C.2
-
15
-
-
70349747006
-
The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis
-
Dopeso H., Mateo-Lozano S., et al. The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis. Cancer Research 2009, 69(18):7430-7438.
-
(2009)
Cancer Research
, vol.69
, Issue.18
, pp. 7430-7438
-
-
Dopeso, H.1
Mateo-Lozano, S.2
-
16
-
-
0033559202
-
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice
-
Edelmann W., Yang K., et al. Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice. Cancer Research 1999, 59(6):1301-1307.
-
(1999)
Cancer Research
, vol.59
, Issue.6
, pp. 1301-1307
-
-
Edelmann, W.1
Yang, K.2
-
17
-
-
4043059169
-
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium
-
El Marjou F., Janssen K.P., et al. Tissue-specific and inducible Cre-mediated recombination in the gut epithelium. Genesis 2004, 39(3):186-193.
-
(2004)
Genesis
, vol.39
, Issue.3
, pp. 186-193
-
-
El Marjou, F.1
Janssen, K.P.2
-
18
-
-
0035863495
-
K-ras and p16 aberrations confer poor prognosis in human colorectal cancer
-
Esteller M., Gonzalez S., et al. K-ras and p16 aberrations confer poor prognosis in human colorectal cancer. Journal of Clinical Oncology 2001, 19(2):299-304.
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.2
, pp. 299-304
-
-
Esteller, M.1
Gonzalez, S.2
-
19
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990, 61(5):759-767.
-
(1990)
Cell
, vol.61
, Issue.5
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
21
-
-
0031216554
-
Molecular biology of colorectal cancer
-
Gryfe R., Bapat B., et al. Molecular biology of colorectal cancer. Current Problems in Cancer 1997, 21(5):233-299.
-
(1997)
Current Problems in Cancer
, vol.21
, Issue.5
, pp. 233-299
-
-
Gryfe, R.1
Bapat, B.2
-
22
-
-
84872084645
-
Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved preclinical orthotopic and adjuvant therapy colon cancer models
-
Hackl C., Man S., et al. Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved preclinical orthotopic and adjuvant therapy colon cancer models. Gut 2012, 65(2):259-271.
-
(2012)
Gut
, vol.65
, Issue.2
, pp. 259-271
-
-
Hackl, C.1
Man, S.2
-
24
-
-
0037108882
-
Compound disruption of Smad2 accelerates malignant progression of intestinal tumors in Apc knockout mice
-
Hamamoto T., Beppu H., et al. Compound disruption of Smad2 accelerates malignant progression of intestinal tumors in Apc knockout mice. Cancer Research 2002, 62(20):5955-5961.
-
(2002)
Cancer Research
, vol.62
, Issue.20
, pp. 5955-5961
-
-
Hamamoto, T.1
Beppu, H.2
-
25
-
-
0033230616
-
Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene
-
Harada N., Tamai Y., et al. Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene. The EMBO Journal 1999, 18(21):5931-5942.
-
(1999)
The EMBO Journal
, vol.18
, Issue.21
, pp. 5931-5942
-
-
Harada, N.1
Tamai, Y.2
-
26
-
-
2442708845
-
Peroxisome proliferator-activated receptor-δ attenuates colon carcinogenesis
-
Harman F.S., Nicol C.J., et al. Peroxisome proliferator-activated receptor-δ attenuates colon carcinogenesis. Nature Medicine 2004, 10(5):481-483.
-
(2004)
Nature Medicine
, vol.10
, Issue.5
, pp. 481-483
-
-
Harman, F.S.1
Nicol, C.J.2
-
27
-
-
35448972047
-
Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation
-
Hinoi T., Akyol A., et al. Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation. Cancer Research 2007, 67(20):9721-9730.
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 9721-9730
-
-
Hinoi, T.1
Akyol, A.2
-
29
-
-
0030019753
-
Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam
-
Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam. Cancer Research 1996, 56(4):710-714.
-
(1996)
Cancer Research
, vol.56
, Issue.4
, pp. 710-714
-
-
Jacoby, R.F.1
Marshall, D.J.2
-
30
-
-
0034665122
-
The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis
-
Jacoby R.F., Seibert K., et al. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Research 2000, 60(18):5040-5044.
-
(2000)
Cancer Research
, vol.60
, Issue.18
, pp. 5040-5044
-
-
Jacoby, R.F.1
Seibert, K.2
-
31
-
-
73449138781
-
Clinicopathological significance of nuclear PTEN expression in colorectal adenocarcinoma
-
Jang K.S., Song Y.S., et al. Clinicopathological significance of nuclear PTEN expression in colorectal adenocarcinoma. Histopathology 2010, 56(2):229-239.
-
(2010)
Histopathology
, vol.56
, Issue.2
, pp. 229-239
-
-
Jang, K.S.1
Song, Y.S.2
-
32
-
-
0035503172
-
1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
-
1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Research 2001, 61(21):7934-7942.
-
(2001)
Cancer Research
, vol.61
, Issue.21
, pp. 7934-7942
-
-
Kuraguchi, M.1
Yang, K.2
-
33
-
-
34250724015
-
Min/+ on mouse chromosome 18
-
Min/+ on mouse chromosome 18. Genetics 2007, 176(2):1237-1244.
-
(2007)
Genetics
, vol.176
, Issue.2
, pp. 1237-1244
-
-
Kwong, L.N.1
Shedlovsky, A.2
-
34
-
-
70350362333
-
PTEN expression and mutation in colorectal carcinomas
-
Li X.H., Zheng H.C., et al. PTEN expression and mutation in colorectal carcinomas. Oncology Reports 2009, 22(4):757-764.
-
(2009)
Oncology Reports
, vol.22
, Issue.4
, pp. 757-764
-
-
Li, X.H.1
Zheng, H.C.2
-
35
-
-
82255179056
-
Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis
-
March H.N., Rust A.G., et al. Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis. Nature Genetics 2011, 43:1202-1209.
-
(2011)
Nature Genetics
, vol.43
, pp. 1202-1209
-
-
March, H.N.1
Rust, A.G.2
-
36
-
-
56749183466
-
Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation
-
Marsh V., Winton D.J., et al. Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation. Nature Genetics 2008, 40(12):1436-1444.
-
(2008)
Nature Genetics
, vol.40
, Issue.12
, pp. 1436-1444
-
-
Marsh, V.1
Winton, D.J.2
-
37
-
-
0037135130
-
Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice
-
Millar C.B., Guy J., et al. Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice. Science 2002, 297(5580):403-405.
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 403-405
-
-
Millar, C.B.1
Guy, J.2
-
38
-
-
74949093198
-
Transforming growth factor-beta. signaling in epithelial-mesenchymal transition and progression of cancer
-
Miyazono K. Transforming growth factor-beta. signaling in epithelial-mesenchymal transition and progression of cancer. Proceedings of the Japan Academy. Series B, Physical and Biological Sciences 2009, 85(8):314-323.
-
(2009)
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
, vol.85
, Issue.8
, pp. 314-323
-
-
Miyazono, K.1
-
39
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser A., Pitot H., et al. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science (New York, NY) 1990, 247(4940):322-324.
-
(1990)
Science (New York, NY)
, vol.247
, Issue.4940
, pp. 322-324
-
-
Moser, A.1
Pitot, H.2
-
40
-
-
0026568524
-
The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system
-
Moser A.R., Dove W.F., et al. The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system. The Journal of Cell Biology 1992, 116(6):1517-1526.
-
(1992)
The Journal of Cell Biology
, vol.116
, Issue.6
, pp. 1517-1526
-
-
Moser, A.R.1
Dove, W.F.2
-
41
-
-
0029143510
-
Min: a mouse model for intestinal and mammary tumorigenesis
-
Min: a mouse model for intestinal and mammary tumorigenesis. European Journal of Cancer 1995, 31(7):1061-1064.
-
(1995)
European Journal of Cancer
, vol.31
, Issue.7
, pp. 1061-1064
-
-
Moser, A.R.1
Luongo, C.2
-
42
-
-
33750565444
-
Transforming growth factor β receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation
-
Muñoz N.M., Upton M., et al. Transforming growth factor β receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Research 2006, 66(20):9837-9844.
-
(2006)
Cancer Research
, vol.66
, Issue.20
, pp. 9837-9844
-
-
Muñoz, N.M.1
Upton, M.2
-
43
-
-
78650624633
-
Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells
-
Nautiyal J., Banerjee S., et al. Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells. International Journal of Cancer 2010, 128(4):951-961.
-
(2010)
International Journal of Cancer
, vol.128
, Issue.4
, pp. 951-961
-
-
Nautiyal, J.1
Banerjee, S.2
-
44
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien C.A., Pollett A., et al. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2006, 445(7123):106-110.
-
(2006)
Nature
, vol.445
, Issue.7123
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
-
46
-
-
0037330524
-
Min mouse: down-regulation of β-catenin signaling by a combination of tea plus sulindac
-
Min mouse: down-regulation of β-catenin signaling by a combination of tea plus sulindac. Carcinogenesis 2003, 24(2):263-267.
-
(2003)
Carcinogenesis
, vol.24
, Issue.2
, pp. 263-267
-
-
Orner, G.A.1
Dashwood, W.2
-
47
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima M., Oshima H., et al. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proceedings of the National Academy of Sciences of the United States of America 1995, 92(10):4482-4486.
-
(1995)
Proceedings of the National Academy of Sciences of the United States of America
, vol.92
, Issue.10
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
-
48
-
-
0030606299
-
Suppression of intestinal polyposis in Apc(Delta 716) knockout mice by inhibition of cyclooxygenase 2 (COX-2)
-
Oshima M., Dinchuk J.E., et al. Suppression of intestinal polyposis in Apc(Delta 716) knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996, 87(5):803-809.
-
(1996)
Cell
, vol.87
, Issue.5
, pp. 803-809
-
-
Oshima, M.1
Dinchuk, J.E.2
-
49
-
-
77956641496
-
+ cancer stem cells with metastatic capacity in human colorectal cancer
-
+ cancer stem cells with metastatic capacity in human colorectal cancer. Cell Stem Cell 2010, 6(6):603-615.
-
(2010)
Cell Stem Cell
, vol.6
, Issue.6
, pp. 603-615
-
-
Pang, R.1
Law, W.L.2
-
50
-
-
23844445836
-
Colorectal cancer: mutations in a signalling pathway
-
Parsons D., Wang T., et al. Colorectal cancer: mutations in a signalling pathway. Nature 2005, 436(7052):792.
-
(2005)
Nature
, vol.436
, Issue.7052
, pp. 792
-
-
Parsons, D.1
Wang, T.2
-
51
-
-
13244273712
-
Foxl1 is a mesenchymal Modifier of Min in carcinogenesis of stomach and colon
-
Perreault N., Sackett S.D., et al. Foxl1 is a mesenchymal Modifier of Min in carcinogenesis of stomach and colon. Science Signalling 2005, 19(3):311-315.
-
(2005)
Science Signalling
, vol.19
, Issue.3
, pp. 311-315
-
-
Perreault, N.1
Sackett, S.D.2
-
52
-
-
42949112116
-
Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype
-
Petrova T.V., Nykänen A., et al. Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype. Cancer Cell 2008, 13(5):407-419.
-
(2008)
Cancer Cell
, vol.13
, Issue.5
, pp. 407-419
-
-
Petrova, T.V.1
Nykänen, A.2
-
53
-
-
52649117105
-
Deficiency of Mbd2 attenuates Wnt signaling
-
Phesse T.J., Parry L., et al. Deficiency of Mbd2 attenuates Wnt signaling. Molecular and Cellular Biology 2008, 28(19):6094-6103.
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.19
, pp. 6094-6103
-
-
Phesse, T.J.1
Parry, L.2
-
54
-
-
0036559462
-
Pathway-specific tumor suppression: reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice
-
Philipp-Staheli J., Kim K.H., et al. Pathway-specific tumor suppression: reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice. Cancer Cell 2002, 1(4):355-368.
-
(2002)
Cancer Cell
, vol.1
, Issue.4
, pp. 355-368
-
-
Philipp-Staheli, J.1
Kim, K.H.2
-
55
-
-
0031882250
-
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair
-
Prolla T.A., Baker S.M., et al. Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair. Nature Genetics 1998, 18(3):276-279.
-
(1998)
Nature Genetics
, vol.18
, Issue.3
, pp. 276-279
-
-
Prolla, T.A.1
Baker, S.M.2
-
56
-
-
0031979329
-
Piroxicam and acarbose as chemopreventive agents for spontaneous intestinal adenomas in Apc gene 1309 knockout mice
-
Quesada C.F., Kimata H., et al. Piroxicam and acarbose as chemopreventive agents for spontaneous intestinal adenomas in Apc gene 1309 knockout mice. Cancer Science 1998, 89(4):392-396.
-
(1998)
Cancer Science
, vol.89
, Issue.4
, pp. 392-396
-
-
Quesada, C.F.1
Kimata, H.2
-
57
-
-
10644231009
-
PPARδ status and Apc-mediated tumourigenesis in the mouse intestine
-
Reed K.R., Sansom O.J., et al. PPARδ status and Apc-mediated tumourigenesis in the mouse intestine. Oncogene 2004, 23(55):8992-8996.
-
(2004)
Oncogene
, vol.23
, Issue.55
, pp. 8992-8996
-
-
Reed, K.R.1
Sansom, O.J.2
-
58
-
-
8944262831
-
MSH2 deficiency contributes to accelerated Apc-mediated intestinal tumorigenesis
-
Reitmair A.H., Cai J.C., et al. MSH2 deficiency contributes to accelerated Apc-mediated intestinal tumorigenesis. Cancer Research 1996, 56(13):2922-2926.
-
(1996)
Cancer Research
, vol.56
, Issue.13
, pp. 2922-2926
-
-
Reitmair, A.H.1
Cai, J.C.2
-
59
-
-
0033566821
-
Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated β-catenin
-
Romagnolo B., Berrebi D., et al. Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated β-catenin. Cancer Research 1999, 59(16):3875-3879.
-
(1999)
Cancer Research
, vol.59
, Issue.16
, pp. 3875-3879
-
-
Romagnolo, B.1
Berrebi, D.2
-
60
-
-
2942668475
-
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
-
Sansom O., Reed K., et al. Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes & Development 2004, 18(12):1385-1390.
-
(2004)
Genes & Development
, vol.18
, Issue.12
, pp. 1385-1390
-
-
Sansom, O.1
Reed, K.2
-
61
-
-
33748988989
-
Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo
-
Sansom O.J., Meniel V., et al. Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo. Proceedings of the National Academy of Sciences of the United States of America 2006, 103(38):14122-14127.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.38
, pp. 14122-14127
-
-
Sansom, O.J.1
Meniel, V.2
-
62
-
-
34247187543
-
Myc deletion rescues Apc deficiency in the small intestine
-
Sansom O.J., Meniel V.S., et al. Myc deletion rescues Apc deficiency in the small intestine. Nature 2007, 446(7136):676-679.
-
(2007)
Nature
, vol.446
, Issue.7136
, pp. 676-679
-
-
Sansom, O.J.1
Meniel, V.S.2
-
63
-
-
67349123408
-
Single Lgr5 stem cells build crypt villus structures in vitro without a mesenchymal niche
-
Sato T., Vries R.G., et al. Single Lgr5 stem cells build crypt villus structures in vitro without a mesenchymal niche. Nature 2009, 459(7244):262-265.
-
(2009)
Nature
, vol.459
, Issue.7244
, pp. 262-265
-
-
Sato, T.1
Vries, R.G.2
-
64
-
-
0030843461
-
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene
-
Shibata H., Toyama K., et al. Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science 1997, 278(5335):120-123.
-
(1997)
Science
, vol.278
, Issue.5335
, pp. 120-123
-
-
Shibata, H.1
Toyama, K.2
-
65
-
-
0036141923
-
Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia
-
Silverman K.A., Koratkar R., et al. Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia. Genome Research 2002, 12(1):88-97.
-
(2002)
Genome Research
, vol.12
, Issue.1
, pp. 88-97
-
-
Silverman, K.A.1
Koratkar, R.2
-
66
-
-
0037047057
-
Mutations in APC, Kirsten-ras, and p53-alternative genetic pathways to colorectal cancer
-
Smith G., Carey F.A., et al. Mutations in APC, Kirsten-ras, and p53-alternative genetic pathways to colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America 2002, 99(14):9433-9438.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.14
, pp. 9433-9438
-
-
Smith, G.1
Carey, F.A.2
-
68
-
-
20144365496
-
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
Solomon S.D., McMurray J.J.V., et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. New England Journal of Medicine 2005, 352(11):1071-1080.
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.11
, pp. 1071-1080
-
-
Solomon, S.D.1
McMurray, J.J.V.2
-
69
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach G., Lynch P.M., et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. New England Journal of Medicine 2000, 342(26):1946-1952.
-
(2000)
New England Journal of Medicine
, vol.342
, Issue.26
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
-
70
-
-
0033057945
-
An ultra-metastatic model of human colon cancer in nude mice
-
Sun F.X., Sasson A.R., et al. An ultra-metastatic model of human colon cancer in nude mice. Clinical and Experimental Metastasis 1999, 17(1):51-58.
-
(1999)
Clinical and Experimental Metastasis
, vol.17
, Issue.1
, pp. 51-58
-
-
Sun, F.X.1
Sasson, A.R.2
-
71
-
-
33751375493
-
Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice
-
Suraweera N., Haines J., et al. Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice. Human Molecular Genetics 2006, 15(23):3429-3435.
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.23
, pp. 3429-3435
-
-
Suraweera, N.1
Haines, J.2
-
72
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
-
Takaku K., Oshima M., et al. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 1998, 92(5):645-656.
-
(1998)
Cell
, vol.92
, Issue.5
, pp. 645-656
-
-
Takaku, K.1
Oshima, M.2
-
73
-
-
33744979495
-
Crypt dynamics and colorectal cancer: advances in mathematical modelling
-
Van Leeuwen I.M.M., Byrne H.M., et al. Crypt dynamics and colorectal cancer: advances in mathematical modelling. Cell Proliferation 2006, 39(3):157-181.
-
(2006)
Cell Proliferation
, vol.39
, Issue.3
, pp. 157-181
-
-
Van Leeuwen, I.M.M.1
Byrne, H.M.2
-
74
-
-
0034645722
-
Min/+(Min) mouse with R-flurbiprofen
-
Min/+(Min) mouse with R-flurbiprofen. Life Sciences 2000, 66(8):745-753.
-
(2000)
Life Sciences
, vol.66
, Issue.8
, pp. 745-753
-
-
Wechter, W.J.1
Murray, E.D.2
-
75
-
-
85047696958
-
ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model
-
Williams K.J., Telfer B.A., et al. ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model. British Journal of Cancer 2002, 86(7):1157-1161.
-
(2002)
British Journal of Cancer
, vol.86
, Issue.7
, pp. 1157-1161
-
-
Williams, K.J.1
Telfer, B.A.2
-
76
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood L.D., Parsons D.W., et al. The genomic landscapes of human breast and colorectal cancers. Science Signalling 2007, 318(5853):1108-1113.
-
(2007)
Science Signalling
, vol.318
, Issue.5853
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
|