Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation

Nature Genetics

Volumn 40, Issue 12, 2008, Pages 1436-1444

  Marsh, Victoria ^a   Winton, Douglas J ^b   Williams, Geraint T ^c   Dubois, Nicole ^d,f   Trumpp, Andreas ^d,g   Sansom, Owen J ^e   Clarke, Alan R ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b Li Ka Shing Centre   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d EPFL   (Switzerland)

^e BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^f UNIVERSITY HEALTH NETWORK   (Canada)

^g GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ADENOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVATION; GENE MUTATION; INTESTINE CARCINOMA; INTESTINE EPITHELIUM; INTESTINE TUMOR; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ADENOMA; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BETA-NAPHTHOFLAVONE; GENE DELETION; INTESTINAL NEOPLASMS; INTESTINE, SMALL; MICE; PTEN PHOSPHOHYDROLASE; TAMOXIFEN;

EID: 56749183466     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.256     Document Type: Article

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