Beltless translocation domain of botulinum neurotoxin A embodies a minimum ion-conductive channel

Journal of Biological Chemistry

Volumn 287, Issue 3, 2012, Pages 1657-1661

  Fischer, Audrey ^a,c   Sambashivan, Shilpa ^b,d   Brunger, Axel T ^b   Montal, Mauricio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY APPLIED PHYSICS LABORATORY   (United States)

^d AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOTULINUM NEUROTOXINS; CATALYTIC DOMAINS; CAUSATIVE AGENTS; CHANNEL FORMATION; CONFORMATIONAL CHANGE; HEAVY CHAIN; ION CONDUCTION; LIGHT CHAIN; PH GRADIENTS; RECEPTOR-BINDING DOMAINS; RECEPTOR-MEDIATED ENDOCYTOSIS; SECONDARY STRUCTURES; STRUCTURAL REARRANGEMENT; TRANSMEMBRANES;

MOLECULAR BIOLOGY;

ACIDIFICATION;

BOTULINUM TOXIN A; ION CHANNEL;

ACIDIFICATION; ANIMAL CELL; ARTICLE; BELTLESS TRANSLOCATION DOMAIN; CONFORMATIONAL TRANSITION; HEAVY CHAIN; ION CONDUCTANCE; LIGHT CHAIN; MEMBRANE CHANNEL; NONHUMAN; PH; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TOXIN STRUCTURE;

BOTULINUM TOXINS, TYPE A; BOTULISM; CELL LINE; HUMANS; ION CHANNELS; MOLECULAR CHAPERONES; PEPTIDE MAPPING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTON-MOTIVE FORCE;

EID: 84855837031     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C111.319400     Document Type: Article

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