Post-intoxication inhibition of botulinum neurotoxin serotype a within neurons by small-molecule, non-peptidic inhibitors

Toxins

Volumn 3, Issue 3, 2011, Pages 207-217

  Ruthel, Gordon ^a   Burnett, James C ^a   Nuss, Jonathan E ^b   Wanner, Laura M ^a   Tressler, Lyal E ^a   Torres Melendez, Edna ^a   Sandwick, Sarah J ^a   Retterer, Cary J ^a   Bavari, Sina ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Bafilomycin A1; Botulinum neurotoxin; Neutralizing antibody; Small molecule non peptidic inhibitor

Indexed keywords

ANTITOXIN; BAFILOMYCIN A1; BOTULINUM TOXIN A; NSC 104999; NSC 95654; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BOTULISM; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; EMBRYO; IN VITRO STUDY; NONHUMAN;

BAFILOMYCIN A1; BOTULINUM NEUROTOXIN; NEUTRALIZING ANTIBODY; SMALL MOLECULE NON-PEPTIDIC INHIBITOR;

ACONITINE; ANIMALS; BLOTTING, WESTERN; BOTULINUM TOXINS, TYPE A; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CHICK EMBRYO; CYTOSOL; IMIDAZOLES; MACROLIDES; MOLECULAR STRUCTURE; MOTOR NEURONS; PHTHALIMIDES; SMALL MOLECULE LIBRARIES; SPINAL CORD; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25; SYNAPTOSOMES;

EID: 79953249923     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins3030207     Document Type: Article

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